FI74995C - Foerfarande foer mikrobiologisk framstaellning av fermenteringsmedia, som innehaoller antingen nebramycin-5' eller en blandning av nebramycin-2, nebramycin-4 och nebramycin-5'. - Google Patents
Foerfarande foer mikrobiologisk framstaellning av fermenteringsmedia, som innehaoller antingen nebramycin-5' eller en blandning av nebramycin-2, nebramycin-4 och nebramycin-5'. Download PDFInfo
- Publication number
- FI74995C FI74995C FI824483A FI824483A FI74995C FI 74995 C FI74995 C FI 74995C FI 824483 A FI824483 A FI 824483A FI 824483 A FI824483 A FI 824483A FI 74995 C FI74995 C FI 74995C
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- FI
- Finland
- Prior art keywords
- nebramycin
- mng
- streptomyces tenebrarius
- fermentation
- strain
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- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 1
- 229960000367 inositol Drugs 0.000 description 1
- 229960000318 kanamycin Drugs 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000010699 lard oil Substances 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 229940061634 magnesium sulfate heptahydrate Drugs 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 239000003471 mutagenic agent Substances 0.000 description 1
- 231100000707 mutagenic chemical Toxicity 0.000 description 1
- 230000003505 mutagenic effect Effects 0.000 description 1
- 230000000422 nocturnal effect Effects 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 238000012803 optimization experiment Methods 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- DLYUQMMRRRQYAE-UHFFFAOYSA-N phosphorus pentoxide Inorganic materials O1P(O2)(=O)OP3(=O)OP1(=O)OP2(=O)O3 DLYUQMMRRRQYAE-UHFFFAOYSA-N 0.000 description 1
- 239000010773 plant oil Substances 0.000 description 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- NGFMICBWJRZIBI-UJPOAAIJSA-N salicin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=CC=C1CO NGFMICBWJRZIBI-UJPOAAIJSA-N 0.000 description 1
- 229940120668 salicin Drugs 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
- 239000011686 zinc sulphate Substances 0.000 description 1
- 235000009529 zinc sulphate Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
- C12P19/48—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
- C12P19/485—Having two saccharide radicals bound through only oxygen to non-adjacent ring carbons of the cyclohexyl radical, e.g. gentamycin, kanamycin, sisomycin, verdamycin, mutamycin, tobramycin, nebramycin, antibiotics 66-40B, 66-40D, XK-62-2, 66-40, G-418, G-52
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
- C12P19/48—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
- C12P19/50—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin having two saccharide radicals bound through only oxygen to adjacent ring carbon atoms of the cyclohexyl radical, e.g. ambutyrosin, ribostamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU813954A HU190680B (en) | 1981-12-28 | 1981-12-28 | Process for preparing 6''-0-carbamoyl-tobramycin microbiologically |
| HU395481 | 1981-12-28 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI824483A0 FI824483A0 (fi) | 1982-12-28 |
| FI824483L FI824483L (fi) | 1983-06-29 |
| FI74995B FI74995B (fi) | 1987-12-31 |
| FI74995C true FI74995C (fi) | 1988-04-11 |
Family
ID=10966213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI824483A FI74995C (fi) | 1981-12-28 | 1982-12-28 | Foerfarande foer mikrobiologisk framstaellning av fermenteringsmedia, som innehaoller antingen nebramycin-5' eller en blandning av nebramycin-2, nebramycin-4 och nebramycin-5'. |
Country Status (9)
| Country | Link |
|---|---|
| AT (1) | AT379171B (en, 2012) |
| BE (1) | BE895455A (en, 2012) |
| CH (2) | CH658072A5 (en, 2012) |
| DE (1) | DE3248420A1 (en, 2012) |
| FI (1) | FI74995C (en, 2012) |
| FR (1) | FR2519023B1 (en, 2012) |
| GB (1) | GB2114978B (en, 2012) |
| HU (1) | HU190680B (en, 2012) |
| NL (1) | NL8205011A (en, 2012) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3691279A (en) * | 1970-04-15 | 1972-09-12 | Lilly Co Eli | Antibiotic nebramycin and preparation thereof |
| US3853709A (en) * | 1970-10-26 | 1974-12-10 | Lilly Co Eli | Process for preparing nebramycin factors ii and vii |
| US4032404A (en) * | 1976-07-14 | 1977-06-28 | Bristol-Myers Company | Fermentation process for producing apramycin and nebramycin factor V' |
-
1981
- 1981-12-28 HU HU813954A patent/HU190680B/hu not_active IP Right Cessation
-
1982
- 1982-12-23 BE BE1/10669A patent/BE895455A/fr not_active IP Right Cessation
- 1982-12-27 FR FR8221803A patent/FR2519023B1/fr not_active Expired
- 1982-12-27 CH CH3108/85A patent/CH658072A5/de not_active IP Right Cessation
- 1982-12-27 CH CH7558/82A patent/CH657374A5/de not_active IP Right Cessation
- 1982-12-28 FI FI824483A patent/FI74995C/fi not_active IP Right Cessation
- 1982-12-28 NL NL8205011A patent/NL8205011A/nl not_active Application Discontinuation
- 1982-12-28 AT AT0470482A patent/AT379171B/de not_active IP Right Cessation
- 1982-12-28 DE DE19823248420 patent/DE3248420A1/de active Granted
- 1982-12-30 GB GB08236905A patent/GB2114978B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| HU190680B (en) | 1986-10-28 |
| DE3248420C2 (en, 2012) | 1990-11-08 |
| GB2114978A (en) | 1983-09-01 |
| AT379171B (de) | 1985-11-25 |
| DE3248420A1 (de) | 1983-07-21 |
| FI824483L (fi) | 1983-06-29 |
| ATA470482A (de) | 1985-04-15 |
| FR2519023A1 (fr) | 1983-07-01 |
| FI824483A0 (fi) | 1982-12-28 |
| CH658072A5 (de) | 1986-10-15 |
| NL8205011A (nl) | 1983-07-18 |
| GB2114978B (en) | 1985-09-11 |
| BE895455A (fr) | 1983-06-23 |
| CH657374A5 (de) | 1986-08-29 |
| FR2519023B1 (fr) | 1985-10-25 |
| FI74995B (fi) | 1987-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed | ||
| MM | Patent lapsed |
Owner name: BIOGAL GYOGYSZERGYAR RT. |