FI69306C - Foerfarande foer framstaellning av antikonvulsiv 2-(3-(4-(3-klor-4-fluorfenyl)-1-piperazinyl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-on - Google Patents

Foerfarande foer framstaellning av antikonvulsiv 2-(3-(4-(3-klor-4-fluorfenyl)-1-piperazinyl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-on Download PDF

Info

Publication number
FI69306C
FI69306C FI811000A FI811000A FI69306C FI 69306 C FI69306 C FI 69306C FI 811000 A FI811000 A FI 811000A FI 811000 A FI811000 A FI 811000A FI 69306 C FI69306 C FI 69306C
Authority
FI
Finland
Prior art keywords
compounds
chloro
triazolo
propyl
pyridin
Prior art date
Application number
FI811000A
Other languages
English (en)
Finnish (fi)
Other versions
FI69306B (fi
FI811000L (fi
Inventor
Bruno Silvestrini
Leandro Baiocchi
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Publication of FI811000L publication Critical patent/FI811000L/fi
Application granted granted Critical
Publication of FI69306B publication Critical patent/FI69306B/fi
Publication of FI69306C publication Critical patent/FI69306C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI811000A 1980-04-09 1981-04-01 Foerfarande foer framstaellning av antikonvulsiv 2-(3-(4-(3-klor-4-fluorfenyl)-1-piperazinyl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-on FI69306C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2124680 1980-04-09
IT21246/80A IT1147349B (it) 1980-04-09 1980-04-09 2-parentesi quadra aperta 3-parentesi quadra aperta 4-(3-cloro-4-fluorofenil)-1-piperfrazinil parentesi quadra propil parentesi quadra chiusa-1,2,4-triazolo parentesi quadra aperta 4,3 parentesi quadra chiusa piridin-3(2h)-one

Publications (3)

Publication Number Publication Date
FI811000L FI811000L (fi) 1981-10-10
FI69306B FI69306B (fi) 1985-09-30
FI69306C true FI69306C (fi) 1986-01-10

Family

ID=11178966

Family Applications (1)

Application Number Title Priority Date Filing Date
FI811000A FI69306C (fi) 1980-04-09 1981-04-01 Foerfarande foer framstaellning av antikonvulsiv 2-(3-(4-(3-klor-4-fluorfenyl)-1-piperazinyl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-on

Country Status (21)

Country Link
US (1) US4402956A (es)
JP (1) JPS56158784A (es)
KR (1) KR840002292B1 (es)
AR (1) AR225076A1 (es)
AT (1) AT377262B (es)
AU (1) AU529605B2 (es)
BE (1) BE887547A (es)
CA (1) CA1176253A (es)
CH (1) CH652397A5 (es)
DE (1) DE3112984A1 (es)
ES (1) ES501188A0 (es)
FI (1) FI69306C (es)
FR (1) FR2480285A1 (es)
GB (1) GB2073747B (es)
GR (1) GR73620B (es)
IL (1) IL62101A (es)
IT (1) IT1147349B (es)
NL (1) NL8100998A (es)
PT (1) PT72813B (es)
SE (1) SE442201B (es)
YU (1) YU83181A (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2269608A1 (en) 1996-11-12 1998-05-22 Sepracor Inc. 2r,4s,s,s- and 2s,4r,s,s-hydroxyitraconazole
JP2001504121A (ja) * 1996-11-12 2001-03-27 セプラコール,インク. 2r,4s,r,s―および2s,4r,r,s―ヒドロキシイトラコナゾール―およびヒドロキシサパーコナゾール誘導体
US6147077A (en) * 1999-04-29 2000-11-14 Sepracor Inc. 2R,4S-hydroxyitraconazole isomers
US8686158B2 (en) * 2008-06-05 2014-04-01 President And Fellows Of Harvard College High-valent palladium fluoride complexes and uses thereof
AU2009316478A1 (en) 2008-11-20 2010-05-27 President And Fellows Of Harvard College Fluorination of organic compounds
AU2010203461A1 (en) * 2009-01-09 2011-07-28 President And Fellows Of Harvard College Fluorine containing compounds and methods of use thereof
US9150516B2 (en) 2011-04-12 2015-10-06 President And Fellows Of Harvard College Fluorination of organic compounds
US9273083B2 (en) 2012-09-26 2016-03-01 President And Fellows Of Harvard College Nickel fluorinating complexes and uses thereof
WO2015058047A2 (en) 2013-10-18 2015-04-23 President And Fellows Of Harvard College Fluorination of organic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
FR8135M (es) * 1968-12-31 1970-08-10
US4218458A (en) * 1978-06-23 1980-08-19 Janssen Pharmaceutica, N.V. Heterocyclic derivatives of (4-aryloxy-methyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
UST100505I4 (en) 1980-03-17 1981-04-07 Triazolo[4,3-a]pyridin-3(2H)-ones

Also Published As

Publication number Publication date
ES8202817A1 (es) 1982-02-01
FR2480285B1 (es) 1984-02-24
KR840002292B1 (ko) 1984-12-15
BE887547A (fr) 1981-06-15
GB2073747B (en) 1983-09-07
US4402956A (en) 1983-09-06
SE442201B (sv) 1985-12-09
AT377262B (de) 1985-02-25
NL8100998A (nl) 1981-11-02
PT72813A (en) 1981-05-01
SE8102093L (sv) 1981-10-10
GR73620B (es) 1984-03-26
YU83181A (en) 1983-12-31
CH652397A5 (it) 1985-11-15
AU6904381A (en) 1981-10-15
AU529605B2 (en) 1983-06-16
IL62101A (en) 1984-01-31
PT72813B (en) 1982-04-02
KR830005218A (ko) 1983-08-03
IT8021246A0 (it) 1980-04-09
FR2480285A1 (fr) 1981-10-16
DE3112984A1 (de) 1981-12-24
FI69306B (fi) 1985-09-30
IL62101A0 (en) 1981-03-31
AR225076A1 (es) 1982-02-15
FI811000L (fi) 1981-10-10
ATA165081A (de) 1984-07-15
JPS56158784A (en) 1981-12-07
GB2073747A (en) 1981-10-21
CA1176253A (en) 1984-10-16
IT1147349B (it) 1986-11-19
ES501188A0 (es) 1982-02-01

Similar Documents

Publication Publication Date Title
DK174618B1 (da) Dibenzothiazepinforbindelse, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater, der indeholder forbindelsen
JP6357475B2 (ja) P2x4受容体拮抗剤
US6316470B1 (en) Benzylpiperazinyl and piperidinyl ethanone derivatives: dopamine receptor subtype specific ligands
SK12332002A3 (sk) Deriváty chinolínu ako alfa 2 antagonisty
FI69306C (fi) Foerfarande foer framstaellning av antikonvulsiv 2-(3-(4-(3-klor-4-fluorfenyl)-1-piperazinyl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2h)-on
AU569537B2 (en) Novel 1-piperazinecarboxamide derivatives
FI80448C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara piperazinkarboxamidderivat.
EP1068193A1 (en) Benzylpiperazinyl- and benzylpiperidinyl ethanone derivatives, their preparation and their use as dopamine d 4? receptor antagonists
FI82454C (fi) Foerfarande foer framstaellning av terapeutiskt aktiva iminotiazolidinderivat.
BG63336B1 (bg) Нови производни на хидроксамови киселини, фармацевтични състави на тяхна основа и метод за получаването им
US6288230B1 (en) 2-(2, 3-dihydrobenzofuran-5-yl)-4-aminomethylimidazoles: dopamine receptor subtype specific ligands
AU2009225272B2 (en) Compounds with antiparasitic activity and medicaments containing them
SE463715B (sv) Psykogeriatriska 1-(2-pyrimidinyl)-piperazinyl-derivat av 1-pyrrolidin-2-oner och foerfarande foer framstaellning av dessa
US5439940A (en) Benz[e]indene derivatives
JP2799892B2 (ja) 新規な誘導体類
JP2021104931A (ja) 含窒素複素環を有するジベンゾアゼピン誘導体
KR900000676B1 (ko) 방향족 w-알킬이미노-테트라하이드로-6h-1,3-티아진-6-온 유도체
CZ327494A3 (en) Esters of nicotinic acid and process for preparing thereof
Obniska et al. Synthesis, physicochemical and anticonvulsant properties of new N-[(4-arylpiperazin-1-yl) alkyl]-3-phenyl-and 3-(3-methyl-phenyl)-pyrrolidine-2, 5-diones
US4094871A (en) 1,3,4-Benzotriazepine-2-thiones
US3536702A (en) 3-aminoalkyl-4,1,3-benzothiadiazepin-2-(1h,3h)-one 4,4-dioxides
US3919311A (en) 3A,12B-Dihydro-8H-dibenzo{8 3,4,6,7{9 cyclohept{8 1,2-d{9 oxazol-8-ones and process for their preparation
WO2000018763A2 (en) 2-(2,3-dihydrobenzofuran-5-yl)-4-aminomethylimidazoles: dopamine receptor subtype specific ligands
CS262163B1 (cs) Aminoacyl- a amínoalkyl-deriváty 6,ll-dihydrodibenzo{b,ejthiepin- -11 aminu a jeha humoíogu, jakož i jejich soli
GB2271994A (en) Benz[e]indene derivatives

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: AZIENDE CHIMICHE RIUNITE ANGELINI