FI68623C - Foerfarande foer framstaellning av nya terapeutiskt aktiva halogenvincamonderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt aktiva halogenvincamonderivat Download PDF

Info

Publication number
FI68623C
FI68623C FI802483A FI802483A FI68623C FI 68623 C FI68623 C FI 68623C FI 802483 A FI802483 A FI 802483A FI 802483 A FI802483 A FI 802483A FI 68623 C FI68623 C FI 68623C
Authority
FI
Finland
Prior art keywords
acid
general formula
framework
active
optically active
Prior art date
Application number
FI802483A
Other languages
English (en)
Finnish (fi)
Other versions
FI68623B (fi
FI802483A (fi
Inventor
Csaba Szantay
Lajos Szabo
Gyoergy Kalaus
Lajos Dancsi
Tibor Keve
Ferenc Drexler
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of FI802483A publication Critical patent/FI802483A/fi
Publication of FI68623B publication Critical patent/FI68623B/fi
Application granted granted Critical
Publication of FI68623C publication Critical patent/FI68623C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI802483A 1979-08-13 1980-08-07 Foerfarande foer framstaellning av nya terapeutiskt aktiva halogenvincamonderivat FI68623C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU79RI722A HU180929B (en) 1979-08-13 1979-08-13 Process for producing new bromo-vincamone derivatives
HURI000722 1979-08-13

Publications (3)

Publication Number Publication Date
FI802483A FI802483A (fi) 1981-02-14
FI68623B FI68623B (fi) 1985-06-28
FI68623C true FI68623C (fi) 1985-10-10

Family

ID=11001105

Family Applications (1)

Application Number Title Priority Date Filing Date
FI802483A FI68623C (fi) 1979-08-13 1980-08-07 Foerfarande foer framstaellning av nya terapeutiskt aktiva halogenvincamonderivat

Country Status (22)

Country Link
US (1) US4356305A (no)
JP (1) JPS5822154B2 (no)
AT (1) AT374200B (no)
AU (1) AU530761B2 (no)
BE (1) BE884620A (no)
CA (1) CA1152076A (no)
CH (1) CH645643A5 (no)
DE (1) DE3026654A1 (no)
DK (1) DK154083C (no)
ES (1) ES8106516A1 (no)
FI (1) FI68623C (no)
FR (1) FR2463139A1 (no)
GB (1) GB2056452B (no)
HU (1) HU180929B (no)
IL (1) IL60588A (no)
IT (1) IT1132403B (no)
NL (1) NL8004348A (no)
NO (1) NO154396C (no)
NZ (1) NZ194653A (no)
PH (1) PH16002A (no)
SE (1) SE441925B (no)
ZA (1) ZA804341B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU187139B (en) * 1982-06-30 1985-11-28 Richter Gedeon Vegyeszet Process for preparing new eburnan derivatives
LU84664A1 (fr) * 1983-02-25 1984-11-08 Onmichem S A Alkyl-4-indolonaphtyridines et leur application therapeutique
DE3340025C2 (de) * 1983-11-03 1986-01-09 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 2-Brom-8-ergolinyl-Verbindungen
JP2581570B2 (ja) * 1987-10-19 1997-02-12 富士写真フイルム株式会社 ビデオ用磁気記録媒体
FR2623501B1 (fr) * 1987-11-19 1990-03-16 Roussel Uclaf Nouveaux derives substitues de 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les renfermant
US5202338A (en) * 1990-10-31 1993-04-13 Vilmos Bar Dihydroquinoline derivatives, pharmaceutical compositions and methods of use of dihydroquinoline derivatives as modulators of the arachidonic acid cascade
JP3135741B2 (ja) * 1993-05-07 2001-02-19 富士写真フイルム株式会社 研磨体
US5573444A (en) * 1993-06-22 1996-11-12 Fuji Photo Film Co., Ltd. Polishing method
US5611826A (en) * 1994-03-01 1997-03-18 Fuji Photo Film Co., Ltd. Abrasive tape

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2085630A1 (en) * 1970-04-07 1971-12-31 Le Men Georges Vincamone compsn - having vasodilator ganglioplegic and antihistamine activity
FR2168853B1 (no) * 1972-01-24 1975-04-25 Centre Etd Ind Pharma
US3852453A (en) * 1972-05-26 1974-12-03 Synthelabo Method of enhancing vincamine compositions
FR2206090A1 (en) * 1972-11-16 1974-06-07 Omnium Chimique Sa Homovincamone-contg. medicaments - with vasodilating, spasmolytic anti-arrhythmic and anti-ischaemic properties
US4146643A (en) * 1973-12-18 1979-03-27 Sandoz Ltd. Increasing vigilance or treating cerebral insufficiency with substituted vincamines
DE2458164A1 (de) * 1973-12-18 1975-06-26 Sandoz Ag Verfahren zur herstellung von neuen heterocyclischen verbindungen
DE2538095A1 (de) * 1974-09-06 1976-03-25 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
FR2339618A1 (fr) * 1976-01-30 1977-08-26 Omnium Chimique Sa Procede de preparation de (-)11-aminovincamone, de 11-aminoeburamonine, de 11-aminovincamone racemique et derives indoliques nouveaux
DE2703920A1 (de) * 1976-02-05 1977-08-11 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
FR2398746A1 (fr) * 1977-07-25 1979-02-23 Roussel Uclaf Nouveaux derives d'alcaloides pentacycliques, leur procede de preparation, leur application comme medicaments, et leur application a la synthese de produits du groupe de l'eburnamonine
FR2407931A1 (fr) * 1977-11-02 1979-06-01 Synthelabo Derives de l'eburnamenine et leur application en therapeutique
DE2922316A1 (de) * 1978-06-12 1979-12-20 Omnium Chimique Sa Neue halogenderivate des vincamins, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
FR2428646A1 (fr) * 1978-06-12 1980-01-11 Omnium Chimique Sa Bromo-10-oxo-16-eburnane et bromo-16-14,15-eburnane, procede pour leur preparation et leur application comme medicaments
FR2428644A2 (fr) * 1978-06-12 1980-01-11 Omnium Chimique Sa Bromo-10-vincamine et bromo-10-14, 15-vincamine, procede pour leur preparation et leur application comme medicaments
FR2445328A1 (fr) * 1978-07-12 1980-07-25 Richter Gedeon Vegyeszet Derives du 14-oxo-e-homo-eburnane, leur procede de preparation et leur utilisation comme medicament
US4285949A (en) * 1978-12-11 1981-08-25 Omnichem Societe Anonyme Vincamine derivatives, their preparation and therapeutical use
HU180928B (en) * 1979-08-06 1983-05-30 Richter Gedeon Vegyeszet Process for preparing new brominated 15-hydroxy-e-homo-eburane derivatives
HU181496B (en) * 1979-08-13 1983-07-28 Richter Gedeon Vegyeszet Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes

Also Published As

Publication number Publication date
NO154396B (no) 1986-06-02
CH645643A5 (de) 1984-10-15
DK347980A (da) 1981-02-14
GB2056452B (en) 1983-10-05
NO802402L (no) 1981-02-16
AU530761B2 (en) 1983-07-28
IT1132403B (it) 1986-07-02
FR2463139B1 (no) 1983-08-26
IT8024150A0 (it) 1980-08-13
HU180929B (en) 1983-05-30
CA1152076A (en) 1983-08-16
IL60588A (en) 1984-05-31
FI68623B (fi) 1985-06-28
ES494086A0 (es) 1981-08-01
ATA396380A (de) 1983-08-15
JPS5626890A (en) 1981-03-16
FI802483A (fi) 1981-02-14
AT374200B (de) 1984-03-26
JPS5822154B2 (ja) 1983-05-06
DK154083B (da) 1988-10-10
DK154083C (da) 1989-02-27
NZ194653A (en) 1982-12-21
SE8005686L (sv) 1981-02-14
ZA804341B (en) 1981-07-29
BE884620A (fr) 1981-02-04
ES8106516A1 (es) 1981-08-01
GB2056452A (en) 1981-03-18
NL8004348A (nl) 1981-02-17
FR2463139A1 (fr) 1981-02-20
IL60588A0 (en) 1980-09-16
US4356305A (en) 1982-10-26
SE441925B (sv) 1985-11-18
PH16002A (en) 1983-05-20
DE3026654A1 (de) 1981-04-16
AU6136980A (en) 1981-02-19
NO154396C (no) 1986-09-10

Similar Documents

Publication Publication Date Title
EP0846118B1 (en) Cyclic gmp-specific phosphodiesterase inhibitors
FI68623C (fi) Foerfarande foer framstaellning av nya terapeutiskt aktiva halogenvincamonderivat
US4605653A (en) 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2H,4H-[1,3]oxazino- or -thiazino-[4,3-a]isoquinoline derivatives and pharmaceutical compositions containing them
US5439906A (en) Antiarrhythmic benzodiazepines
EP0417631A2 (de) Kondensierte Diazepinone, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
HU203891B (en) Process for producing pyrrolidino-piperazine-dion derivatives and pharmaceutical compositions contianing them as active components
US5116837A (en) 2,9-dihydro-(6 or 7)-(3-oxo-2,3,4,5-tetrahydropyridazinyl)-pyrazolo [4,3-B]-1,4-benzoxazines
DD249271A5 (de) Verfahren zur herstellung von 9-chlor-1,5-benzothiazepin-derivaten
CZ100094A3 (en) 2-amino-4-quinolyl dihydropyridines, process of their preparation, medicaments in which they are comprised, process of their preparation and the use of said compounds
FI67382B (fi) Foerfarande foer framstaellning av ny kaerlvidgande 10-brom-14-oxo-15-hydroxi-e-homo-eburnan
US4138564A (en) Tetrahydro[1H]pyrazino[1,2-a]azaquinoxalin-5(6H)-ones and derivatives thereof
CA1299574C (en) (1)-1.beta.-ETHYL-1.alpha.-HYDROXYMETHYL-1,2,3,4,6,7,12,12-.beta. .alpha.-OCTAHYDROINDOLO ¬2,3-A| QUINOLIZINE, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
CS203184B2 (en) Process for preparing new pyrroloquinoxalinones and pyrrolobenzodiazepinones
EP0443312B1 (en) 3H,6H-1,4,5a,8a-Tetraazaacenaphthylene-3,5-(4H)-diones
US4843080A (en) 1,12-disubstituted octahydroindolo[2,3-]quinolizine derivatives, pharmaceutical compositions
EP0653426B1 (en) Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same
HU192728B (en) Process for producing 4-oxo-pyrido/2,3-d/pyrimidine derivatives and pharmaceutical compositions containing them
US4225713A (en) Tetrahydro(1H)pyrazino(1,2-A)azaquinoxalin-5(6H)-ones and derivatives thereof
EP0200436A2 (en) 12b-Substituted 1-hydroxymethyl-octahydroindolo[2,3-a]quinolizine derivatives
KR100390767B1 (ko) 아지리디닐퀴놀린디온 유도체와 그의 제조방법
US4681885A (en) 5-oxo-pyrido[4,3-]pyrimidine derivatives
HU194863B (en) Process for producing 5-amino-1,2-dithiol-3-one derivatives and pharmaceutical compositions containing them
EP4101848A1 (en) Pde4 inhibitor compound and medical use thereof
KR950013764B1 (ko) 피로글루타미드 유도체, 그 제조방법, 및 그것을 함유하는 치매증 치료제
FI81580B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara pyridazopyridazinderivat och nya mellanprodukter.

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: RICHTER GEDEON VEGYESZETI GYOER R.T.