FI68402C - Foerfarande foer framstaellning av ett terapeutiskt anvaendbart 9-(2-hydroxietoximetyl)guaninmonofosfatderivat - Google Patents

Foerfarande foer framstaellning av ett terapeutiskt anvaendbart 9-(2-hydroxietoximetyl)guaninmonofosfatderivat Download PDF

Info

Publication number
FI68402C
FI68402C FI780626A FI780626A FI68402C FI 68402 C FI68402 C FI 68402C FI 780626 A FI780626 A FI 780626A FI 780626 A FI780626 A FI 780626A FI 68402 C FI68402 C FI 68402C
Authority
FI
Finland
Prior art keywords
compound
formula
process according
group
converted
Prior art date
Application number
FI780626A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI780626A (fi
FI68402B (fi
Inventor
Howard John Schaeffer
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI780626A publication Critical patent/FI780626A/fi
Application granted granted Critical
Publication of FI68402B publication Critical patent/FI68402B/fi
Publication of FI68402C publication Critical patent/FI68402C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
FI780626A 1977-02-24 1978-02-24 Foerfarande foer framstaellning av ett terapeutiskt anvaendbart 9-(2-hydroxietoximetyl)guaninmonofosfatderivat FI68402C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US77177877A 1977-02-24 1977-02-24
US77177877 1977-02-24
GB5390577 1977-12-24
GB5390577 1977-12-24

Publications (3)

Publication Number Publication Date
FI780626A FI780626A (fi) 1978-08-25
FI68402B FI68402B (fi) 1985-05-31
FI68402C true FI68402C (fi) 1985-09-10

Family

ID=26267373

Family Applications (1)

Application Number Title Priority Date Filing Date
FI780626A FI68402C (fi) 1977-02-24 1978-02-24 Foerfarande foer framstaellning av ett terapeutiskt anvaendbart 9-(2-hydroxietoximetyl)guaninmonofosfatderivat

Country Status (27)

Country Link
JP (1) JPS53108999A (it)
AR (2) AR219735A1 (it)
AT (1) AT353286B (it)
AU (1) AU521577B2 (it)
CA (1) CA1094062A (it)
CH (1) CH643858A5 (it)
DD (1) DD134098A5 (it)
DE (1) DE2808096A1 (it)
DK (1) DK147198C (it)
ES (2) ES467300A1 (it)
FI (1) FI68402C (it)
FR (1) FR2381781A1 (it)
GR (1) GR64404B (it)
HU (1) HU178808B (it)
IE (1) IE46210B1 (it)
IL (1) IL54130A0 (it)
IN (1) IN149483B (it)
IT (1) IT1105259B (it)
LU (1) LU79126A1 (it)
MC (1) MC1182A1 (it)
NL (1) NL7802111A (it)
NO (1) NO153260C (it)
NZ (1) NZ186555A (it)
PH (1) PH13996A (it)
PL (1) PL114474B1 (it)
PT (1) PT67706B (it)
SE (1) SE430507B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0015584A3 (de) * 1979-03-12 1980-12-10 Kailash Kumar Dr. Prof. Gauri Neue Nukleotide, Verfahren zu ihrer Herstellung und Arzneimittel
EP0272446B1 (en) * 1983-05-24 1992-11-11 Sri International Novel antiviral agents
US5047533A (en) * 1983-05-24 1991-09-10 Sri International Acyclic purine phosphonate nucleotide analogs
US4579849A (en) * 1984-04-06 1986-04-01 Merck & Co., Inc. N-alkylguanine acyclonucleosides as antiviral agents
CS264222B1 (en) * 1986-07-18 1989-06-13 Holy Antonin N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them
AU5511196A (en) * 1995-04-21 1996-11-07 Centre National De La Recherche Scientifique (Cnrs) Acyclovir derivatives as antiviral agents
FR2733234B1 (fr) * 1995-04-21 1997-07-04 Centre Nat Rech Scient Derives de l'acyclovir comme agents antiviraux

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof

Also Published As

Publication number Publication date
NO153260B (no) 1985-11-04
LU79126A1 (fr) 1978-10-17
NZ186555A (en) 1981-02-11
IT7848192A0 (it) 1978-02-24
AR219735A1 (es) 1980-09-15
IE46210B1 (en) 1983-03-23
ATA134678A (de) 1979-04-15
AR218718A1 (es) 1980-06-30
PL114474B1 (en) 1981-01-31
DD134098A5 (de) 1979-02-07
FR2381781A1 (fr) 1978-09-22
ES470383A1 (es) 1979-09-16
PT67706B (en) 1980-03-04
FI780626A (fi) 1978-08-25
NL7802111A (nl) 1978-08-28
IT1105259B (it) 1985-10-28
DK147198B (da) 1984-05-14
AT353286B (de) 1979-11-12
CA1094062A (en) 1981-01-20
GR64404B (en) 1980-03-21
DK85178A (da) 1978-08-25
PL204885A1 (pl) 1979-04-23
AU521577B2 (en) 1982-04-22
IL54130A0 (en) 1978-04-30
ES467300A1 (es) 1978-10-16
PT67706A (en) 1978-03-01
PH13996A (en) 1980-11-28
NO153260C (no) 1986-02-12
DE2808096C2 (it) 1988-02-18
SE430507B (sv) 1983-11-21
IN149483B (it) 1981-12-26
MC1182A1 (fr) 1978-12-22
HU178808B (en) 1982-06-28
JPS53108999A (en) 1978-09-22
CH643858A5 (en) 1984-06-29
FI68402B (fi) 1985-05-31
SE7802140L (sv) 1978-08-25
DE2808096A1 (de) 1978-08-31
NO780644L (no) 1978-08-25
IE780397L (en) 1978-08-24
FR2381781B1 (it) 1980-04-25
DK147198C (da) 1984-11-12
AU3356078A (en) 1979-08-30

Similar Documents

Publication Publication Date Title
US4579849A (en) N-alkylguanine acyclonucleosides as antiviral agents
US4287188A (en) Purine derivatives
US4670424A (en) Cyclic pyrophosphates of purine and pyrimidine acyclonucleosides
US6767900B2 (en) Phosphonate nucleotide compound
EP0785208B1 (en) Phosphonate nucleotide compounds
US4608368A (en) 1-hydroxy-1,1-diphosphonic acids and cytostatic use thereof
FI68402B (fi) Foerfarande foer framstaellning av ett terapeutiskt anvaendbart 9-(2-hydroxietoximetyl)guaninmonofosfatderivat
US4590269A (en) Process for preparing the cyclic phosphate ester of substituted 9-(1,3-dihydroxy-2-propoxymethyl)purines
GB2122198A (en) Antiviral guanine derivatives
GB1590500A (en) Phosphorus containing guanine derivatives having antiviral activity
EP0138683A2 (en) Purine derivatives, their application in anti-viral compositions
CA2037687C (en) 7-(diphenylmethyl)oxy-9a-methoxymitosane and making and use thereof
CA2181474C (en) Process for the production of asymmetrical phosphoric acid diesters
IE51332B1 (en) Novel adenine nucleoside derivatives,their preparation and pharmaceutical compositions containing them
US4897479A (en) Arylsulfonyloxy purine intermediates
Kazimierczuk et al. http://rcin. org. pl
US3868361A (en) s-Triazolo{8 2,3-A{9 {0 pryimidine nucleosides
CS248005B2 (cs) Způsob výroby derivátů 9-hydroxyethoxymethylguaninu
US5733890A (en) Adenylate analogs as potent anti-herpes virus agents
JP3148139B2 (ja) ホスホナートヌクレオチド化合物
CS248003B2 (cs) Způsob výroby derivátů 9-hydroxyethoxymethylguaninu
US4966895A (en) Cyclic monophosphates of purine and pyrimidine acyclonucleosides as anti-retroviral agents
KR840002464B1 (ko) 지방족 포스포노포름산 모노에스테르의 제조방법
CA1287832C (en) Anti-viral compounds
HU190787B (en) Process for producing new guanine derivatives

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: THE WELLCOME FOUNDATION LIMITED