CA1094062A - 9-(2-hydroxyethoxymethyl) guanine monophosphate derivatives - Google Patents

9-(2-hydroxyethoxymethyl) guanine monophosphate derivatives

Info

Publication number
CA1094062A
CA1094062A CA297,833A CA297833A CA1094062A CA 1094062 A CA1094062 A CA 1094062A CA 297833 A CA297833 A CA 297833A CA 1094062 A CA1094062 A CA 1094062A
Authority
CA
Canada
Prior art keywords
formula
hydroxyethoxymethyl
guanine
compound
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA297,833A
Other languages
English (en)
French (fr)
Inventor
Howard J. Schaeffer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Application granted granted Critical
Publication of CA1094062A publication Critical patent/CA1094062A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
CA297,833A 1977-02-24 1978-02-24 9-(2-hydroxyethoxymethyl) guanine monophosphate derivatives Expired CA1094062A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US77177877A 1977-02-24 1977-02-24
US771,778 1977-02-24
GB53905/77 1977-12-24
GB5390577 1977-12-24

Publications (1)

Publication Number Publication Date
CA1094062A true CA1094062A (en) 1981-01-20

Family

ID=26267373

Family Applications (1)

Application Number Title Priority Date Filing Date
CA297,833A Expired CA1094062A (en) 1977-02-24 1978-02-24 9-(2-hydroxyethoxymethyl) guanine monophosphate derivatives

Country Status (27)

Country Link
JP (1) JPS53108999A (it)
AR (2) AR219735A1 (it)
AT (1) AT353286B (it)
AU (1) AU521577B2 (it)
CA (1) CA1094062A (it)
CH (1) CH643858A5 (it)
DD (1) DD134098A5 (it)
DE (1) DE2808096A1 (it)
DK (1) DK147198C (it)
ES (2) ES467300A1 (it)
FI (1) FI68402C (it)
FR (1) FR2381781A1 (it)
GR (1) GR64404B (it)
HU (1) HU178808B (it)
IE (1) IE46210B1 (it)
IL (1) IL54130A0 (it)
IN (1) IN149483B (it)
IT (1) IT1105259B (it)
LU (1) LU79126A1 (it)
MC (1) MC1182A1 (it)
NL (1) NL7802111A (it)
NO (1) NO153260C (it)
NZ (1) NZ186555A (it)
PH (1) PH13996A (it)
PL (1) PL114474B1 (it)
PT (1) PT67706B (it)
SE (1) SE430507B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0015584A3 (de) * 1979-03-12 1980-12-10 Kailash Kumar Dr. Prof. Gauri Neue Nukleotide, Verfahren zu ihrer Herstellung und Arzneimittel
EP0272446B1 (en) * 1983-05-24 1992-11-11 Sri International Novel antiviral agents
US5047533A (en) * 1983-05-24 1991-09-10 Sri International Acyclic purine phosphonate nucleotide analogs
US4579849A (en) * 1984-04-06 1986-04-01 Merck & Co., Inc. N-alkylguanine acyclonucleosides as antiviral agents
CS264222B1 (en) * 1986-07-18 1989-06-13 Holy Antonin N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them
AU5511196A (en) * 1995-04-21 1996-11-07 Centre National De La Recherche Scientifique (Cnrs) Acyclovir derivatives as antiviral agents
FR2733234B1 (fr) * 1995-04-21 1997-07-04 Centre Nat Rech Scient Derives de l'acyclovir comme agents antiviraux

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof

Also Published As

Publication number Publication date
NO153260B (no) 1985-11-04
LU79126A1 (fr) 1978-10-17
NZ186555A (en) 1981-02-11
IT7848192A0 (it) 1978-02-24
AR219735A1 (es) 1980-09-15
IE46210B1 (en) 1983-03-23
ATA134678A (de) 1979-04-15
AR218718A1 (es) 1980-06-30
PL114474B1 (en) 1981-01-31
DD134098A5 (de) 1979-02-07
FR2381781A1 (fr) 1978-09-22
ES470383A1 (es) 1979-09-16
PT67706B (en) 1980-03-04
FI780626A (fi) 1978-08-25
NL7802111A (nl) 1978-08-28
IT1105259B (it) 1985-10-28
DK147198B (da) 1984-05-14
AT353286B (de) 1979-11-12
GR64404B (en) 1980-03-21
DK85178A (da) 1978-08-25
PL204885A1 (pl) 1979-04-23
AU521577B2 (en) 1982-04-22
IL54130A0 (en) 1978-04-30
ES467300A1 (es) 1978-10-16
PT67706A (en) 1978-03-01
PH13996A (en) 1980-11-28
NO153260C (no) 1986-02-12
FI68402C (fi) 1985-09-10
DE2808096C2 (it) 1988-02-18
SE430507B (sv) 1983-11-21
IN149483B (it) 1981-12-26
MC1182A1 (fr) 1978-12-22
HU178808B (en) 1982-06-28
JPS53108999A (en) 1978-09-22
CH643858A5 (en) 1984-06-29
FI68402B (fi) 1985-05-31
SE7802140L (sv) 1978-08-25
DE2808096A1 (de) 1978-08-31
NO780644L (no) 1978-08-25
IE780397L (en) 1978-08-24
FR2381781B1 (it) 1980-04-25
DK147198C (da) 1984-11-12
AU3356078A (en) 1979-08-30

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Legal Events

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