FI67708C - Foerfarande foer framstaellning av antibiotisk n-glukosylderivat av daunorubicin eller adriamycin - Google Patents

Foerfarande foer framstaellning av antibiotisk n-glukosylderivat av daunorubicin eller adriamycin Download PDF

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Publication number
FI67708C
FI67708C FI802332A FI802332A FI67708C FI 67708 C FI67708 C FI 67708C FI 802332 A FI802332 A FI 802332A FI 802332 A FI802332 A FI 802332A FI 67708 C FI67708 C FI 67708C
Authority
FI
Finland
Prior art keywords
daunorubicin
adriamycin
antibiotics
glucosylder
eller
Prior art date
Application number
FI802332A
Other languages
English (en)
Finnish (fi)
Other versions
FI802332A (fi
FI67708B (fi
Inventor
Barbara Stefanska
Leonard Falkowski
Edward Borowski
Original Assignee
Politechnika Gdanska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Gdanska filed Critical Politechnika Gdanska
Publication of FI802332A publication Critical patent/FI802332A/fi
Publication of FI67708B publication Critical patent/FI67708B/fi
Application granted granted Critical
Publication of FI67708C publication Critical patent/FI67708C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI802332A 1979-10-17 1980-07-24 Foerfarande foer framstaellning av antibiotisk n-glukosylderivat av daunorubicin eller adriamycin FI67708C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PL21904979 1979-10-17
PL1979219049A PL124284B1 (en) 1979-10-17 1979-10-17 Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group

Publications (3)

Publication Number Publication Date
FI802332A FI802332A (fi) 1981-04-18
FI67708B FI67708B (fi) 1985-01-31
FI67708C true FI67708C (fi) 1985-05-10

Family

ID=19998972

Family Applications (1)

Application Number Title Priority Date Filing Date
FI802332A FI67708C (fi) 1979-10-17 1980-07-24 Foerfarande foer framstaellning av antibiotisk n-glukosylderivat av daunorubicin eller adriamycin

Country Status (11)

Country Link
US (1) US4351937A (de)
JP (1) JPS5914479B2 (de)
BE (1) BE884318A (de)
DE (1) DE3028148C2 (de)
DK (1) DK305880A (de)
FI (1) FI67708C (de)
FR (1) FR2473524A1 (de)
GB (1) GB2060609B (de)
PL (1) PL124284B1 (de)
SE (1) SE8005099L (de)
SU (2) SU1011051A3 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH648327A5 (de) * 1980-10-16 1985-03-15 Hoffmann La Roche Anthracycline.
JPS6297A (ja) * 1985-06-24 1987-01-06 Microbial Chem Res Found アントラサイクリン化合物
US4863739A (en) * 1987-05-19 1989-09-05 Board Of Regents, The University Of Texas System Liposome compositions of anthracycline derivatives
WO1989006654A1 (en) * 1988-01-19 1989-07-27 Board Of Regents, The University Of Texas System Glycosides, liposomal compositions thereof, and methods for their use
DE69425356T2 (de) * 1993-09-22 2002-04-18 Hoechst Ag Pro-Prodrugs, ihre Herstellung und Anwendung
GB9727546D0 (en) * 1997-12-31 1998-03-18 Pharmacia & Upjohn Spa Anthracycline glycosides
CA2366681C (en) * 1999-03-19 2009-12-22 Waldemar Priebe Methods and compositions for the manufacture of c-3' and c-4' anthracycline antibiotics
CA2394833A1 (en) 2000-01-14 2001-07-19 Binh T. Dang Derivatives of polyene macrolides and preparation and use thereof
CN104211738B (zh) * 2014-08-15 2016-09-28 合肥合源药业有限公司 一种伊达比星中的杂质、其制备方法及其应用
RU2642068C1 (ru) * 2017-04-26 2018-01-24 Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) N-пиперонильные производные даунорубицина, обладающие антипролиферативными свойствами

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI60877C (fi) * 1971-08-13 1982-04-13 Politechnika Gdanska Foerfarande foer framstaellning av terapeutiskt aktiva i vatten laett dispergerbara polyenmakrolidantibiot-n-glykosylderivat
JPS5323961A (en) * 1976-08-16 1978-03-06 Microbial Chem Res Found Antitumors
GB1561507A (en) * 1976-11-17 1980-02-20 Farmaceutici Italia Snthracycline disaccharides
GB2007645B (en) * 1977-10-17 1982-05-12 Stanford Res Inst Int Benzyl anthracyclines and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DK305880A (da) 1981-04-18
JPS5914479B2 (ja) 1984-04-04
SU1011051A3 (ru) 1983-04-07
FR2473524B1 (de) 1983-06-03
PL124284B1 (en) 1983-01-31
SE8005099L (sv) 1981-04-18
FI802332A (fi) 1981-04-18
FI67708B (fi) 1985-01-31
JPS5663994A (en) 1981-05-30
BE884318A (fr) 1980-11-03
DE3028148A1 (de) 1981-04-30
PL219049A1 (de) 1981-05-08
FR2473524A1 (fr) 1981-07-17
SU1054352A1 (ru) 1983-11-15
GB2060609B (en) 1984-09-05
GB2060609A (en) 1981-05-07
US4351937A (en) 1982-09-28
DE3028148C2 (de) 1984-10-25

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Owner name: POLITECHNIKA GDANSKA