FI67692C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tripeptider - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tripeptider Download PDF

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Publication number
FI67692C
FI67692C FI800780A FI800780A FI67692C FI 67692 C FI67692 C FI 67692C FI 800780 A FI800780 A FI 800780A FI 800780 A FI800780 A FI 800780A FI 67692 C FI67692 C FI 67692C
Authority
FI
Finland
Prior art keywords
resin
cells
amino
sar
amino acid
Prior art date
Application number
FI800780A
Other languages
English (en)
Finnish (fi)
Other versions
FI800780A (fi
FI67692B (fi
Inventor
Gideon Goldstein
George Heavner
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of FI800780A publication Critical patent/FI800780A/fi
Publication of FI67692B publication Critical patent/FI67692B/fi
Application granted granted Critical
Publication of FI67692C publication Critical patent/FI67692C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/18—Thymus derived hormone or factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI800780A 1979-03-14 1980-03-13 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tripeptider FI67692C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/020,159 US4215112A (en) 1979-03-14 1979-03-14 Tripeptides and methods
US2015979 1979-03-14

Publications (3)

Publication Number Publication Date
FI800780A FI800780A (fi) 1980-09-15
FI67692B FI67692B (fi) 1985-01-31
FI67692C true FI67692C (fi) 1985-05-10

Family

ID=21797075

Family Applications (1)

Application Number Title Priority Date Filing Date
FI800780A FI67692C (fi) 1979-03-14 1980-03-13 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tripeptider

Country Status (18)

Country Link
US (1) US4215112A (fr)
EP (1) EP0016611B1 (fr)
JP (1) JPS55143945A (fr)
AT (1) ATE4452T1 (fr)
AU (1) AU531556B2 (fr)
CA (1) CA1141375A (fr)
DE (1) DE3064559D1 (fr)
DK (1) DK149092C (fr)
ES (1) ES8103027A1 (fr)
FI (1) FI67692C (fr)
GR (1) GR68039B (fr)
IE (1) IE49289B1 (fr)
IL (1) IL59604A (fr)
NO (1) NO149997C (fr)
NZ (1) NZ193063A (fr)
PT (1) PT70936B (fr)
YU (1) YU41914B (fr)
ZA (1) ZA801482B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4369137A (en) * 1980-06-17 1983-01-18 Ortho Pharmaceutical Corporation N-Protected pentapeptides useful as intermediates in the preparation of thymopoietin pentapeptide
US4298523A (en) * 1980-06-17 1981-11-03 Ortho Pharmaceutical Corporation Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R
US4454065A (en) * 1982-05-18 1984-06-12 Smithkline Beckman Corporation Oligopeptide prodrugs
US4481191A (en) * 1983-03-30 1984-11-06 The Regents Of The University Of California Method for controlling blood pressure
US4683292A (en) * 1983-08-12 1987-07-28 Immunetech, Inc. Immunotherapeutic polypeptide agents which bind to lymphocyte immunoglobulin FC receptors
EP0215805A1 (fr) * 1985-01-18 1987-04-01 MERCK PATENT GmbH Peptides de regulation immunitaire
US4584284A (en) * 1985-01-31 1986-04-22 Ortho Pharmaceutical Corporation Bursopoietin
IT1188646B (it) * 1986-04-09 1988-01-20 Ellem Ind Farmaceutica Tripeptide ad attivita' immunostimolante
IT1196958B (it) * 1986-07-10 1988-11-25 Ellem Ind Farmaceutica Derivato di timo attivo per via orale, procedimenti per la sua preparazione e relative composizioni farmaceutiche
ATE136551T1 (de) * 1988-05-10 1996-04-15 Alpha 1 Biomedicals Inc Festphase-verfahren zur gewinnung von thymosin- alpha-1
HU201964B (en) * 1989-01-13 1991-01-28 Richter Gedeon Vegyeszet Process for producing peptides inhibiting maturation of t-lymphocytes and activity of macrophages, as well as pharmaceutical compositions comprising same
US6258932B1 (en) * 1999-08-09 2001-07-10 Tripep Ab Peptides that block viral infectivity and methods of use thereof
MXPA02001349A (es) * 1999-08-09 2002-07-22 Tripep Ab Inhibidores de la polimerizacion de proteinas y metodos de uso.
US6593455B2 (en) * 2001-08-24 2003-07-15 Tripep Ab Tripeptide amides that block viral infectivity and methods of use thereof
US6455670B1 (en) * 2001-09-06 2002-09-24 Tripep Ab Pentamer peptide amide, ALGPG-NH2, that inhibits viral infectivity and methods of use thereof
EP1436317A1 (fr) * 2001-09-19 2004-07-14 Tripep Ab Molecules bloquant l'infectivite virale et methodes d'utilisation associees
US20050096319A1 (en) * 2003-02-21 2005-05-05 Balzarini Jan M.R. Identification of compounds that inhibit replication of human immunodeficiency virus
KR20050101221A (ko) * 2003-02-21 2005-10-20 트리펩 아베 Ｈｉｖ 복제의 억제를 위한 글리신아미드 유도체

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4098777A (en) * 1977-03-14 1978-07-04 Merck & Co., Inc. Process for the preparation of pyroglutamyl-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn
FR2391994A1 (fr) * 1977-05-25 1978-12-22 Anvar Nouveaux polypeptides a activite thymique ou a activite antagoniste et leurs procedes de synthese
SE446867B (sv) * 1977-11-15 1986-10-13 Sloan Kettering Inst Cancer Sett att framstella en polypeptid med formaga att inducera differentiering av t-lymfocyter men inte av komplementreceptor (cr?72+) b-lymfocyter
SE446866B (sv) * 1977-11-15 1986-10-13 Sloan Kettering Inst Cancer Sett att framstella en aktiv polypeptid med formaga att inducera differentiering av bade t-lymfocyter och komplementreceptor (cr?72+) b-lymfocyter
NZ189101A (en) * 1977-12-08 1984-07-06 Ortho Pharma Corp Polypeptides having the ability to induce differentiation of both th-1+ t-lymphocytes and bu-1+ b-lymphocytes;pharmaceutical compositions

Also Published As

Publication number Publication date
PT70936B (en) 1981-06-24
EP0016611A3 (en) 1981-01-07
DE3064559D1 (en) 1983-09-22
ZA801482B (en) 1981-10-28
IL59604A (en) 1983-02-23
GR68039B (fr) 1981-10-27
NO800723L (no) 1980-09-15
DK109280A (da) 1980-09-15
AU531556B2 (en) 1983-08-25
FI800780A (fi) 1980-09-15
FI67692B (fi) 1985-01-31
JPS55143945A (en) 1980-11-10
DK149092C (da) 1986-06-16
DK149092B (da) 1986-01-20
PT70936A (en) 1980-04-01
ES489522A0 (es) 1981-02-16
IE49289B1 (en) 1985-09-04
NO149997B (no) 1984-04-24
IE800514L (en) 1980-09-14
NZ193063A (en) 1984-07-06
NO149997C (no) 1984-08-01
EP0016611B1 (fr) 1983-08-17
ES8103027A1 (es) 1981-02-16
YU69880A (en) 1983-02-28
EP0016611A2 (fr) 1980-10-01
CA1141375A (fr) 1983-02-15
IL59604A0 (en) 1980-06-30
ATE4452T1 (de) 1983-09-15
YU41914B (en) 1988-02-29
US4215112A (en) 1980-07-29
AU5631280A (en) 1980-09-18

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FI70905B (fi) Analogifoerfarande foer framstaellning av terapeutiskt anvaendbara pentapeptidderivat vilka har biologisk foermaoga att inucera differentiering av t-lymfocyter men ej av komplemen trceptor-(cr+)-b-lymfocyter
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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: ORTHO PHARMACEUTICAL CORPORATION