ATE4452T1 - Tripeptide, verfahren zu ihrer herstellung, sie enthaltende therapeutische zusammensetzungen und methoden ihrer anwendung. - Google Patents
Tripeptide, verfahren zu ihrer herstellung, sie enthaltende therapeutische zusammensetzungen und methoden ihrer anwendung.Info
- Publication number
- ATE4452T1 ATE4452T1 AT80300770T AT80300770T ATE4452T1 AT E4452 T1 ATE4452 T1 AT E4452T1 AT 80300770 T AT80300770 T AT 80300770T AT 80300770 T AT80300770 T AT 80300770T AT E4452 T1 ATE4452 T1 AT E4452T1
- Authority
- AT
- Austria
- Prior art keywords
- polypeptides
- thr
- ala
- methods
- therapeutic compositions
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 230000004069 differentiation Effects 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 230000002992 thymic effect Effects 0.000 abstract 2
- 206010010356 Congenital anomaly Diseases 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N THREONINE Chemical compound CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 210000001541 thymus gland Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/18—Thymus derived hormone or factor; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/020,159 US4215112A (en) | 1979-03-14 | 1979-03-14 | Tripeptides and methods |
| EP80300770A EP0016611B1 (de) | 1979-03-14 | 1980-03-13 | Tripeptide, Verfahren zu ihrer Herstellung, sie enthaltende therapeutische Zusammensetzungen und Methoden ihrer Anwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE4452T1 true ATE4452T1 (de) | 1983-09-15 |
Family
ID=21797075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT80300770T ATE4452T1 (de) | 1979-03-14 | 1980-03-13 | Tripeptide, verfahren zu ihrer herstellung, sie enthaltende therapeutische zusammensetzungen und methoden ihrer anwendung. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4215112A (de) |
| EP (1) | EP0016611B1 (de) |
| JP (1) | JPS55143945A (de) |
| AT (1) | ATE4452T1 (de) |
| AU (1) | AU531556B2 (de) |
| CA (1) | CA1141375A (de) |
| DE (1) | DE3064559D1 (de) |
| DK (1) | DK149092C (de) |
| ES (1) | ES8103027A1 (de) |
| FI (1) | FI67692C (de) |
| GR (1) | GR68039B (de) |
| IE (1) | IE49289B1 (de) |
| IL (1) | IL59604A (de) |
| NO (1) | NO149997C (de) |
| NZ (1) | NZ193063A (de) |
| PT (1) | PT70936B (de) |
| YU (1) | YU41914B (de) |
| ZA (1) | ZA801482B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4298523A (en) * | 1980-06-17 | 1981-11-03 | Ortho Pharmaceutical Corporation | Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R |
| US4369137A (en) * | 1980-06-17 | 1983-01-18 | Ortho Pharmaceutical Corporation | N-Protected pentapeptides useful as intermediates in the preparation of thymopoietin pentapeptide |
| US4454065A (en) * | 1982-05-18 | 1984-06-12 | Smithkline Beckman Corporation | Oligopeptide prodrugs |
| US4481191A (en) * | 1983-03-30 | 1984-11-06 | The Regents Of The University Of California | Method for controlling blood pressure |
| US4683292A (en) * | 1983-08-12 | 1987-07-28 | Immunetech, Inc. | Immunotherapeutic polypeptide agents which bind to lymphocyte immunoglobulin FC receptors |
| AU602483B2 (en) * | 1985-01-18 | 1990-10-18 | Immunetech Pharmaceuticals | Immunoregulatory peptides |
| US4584284A (en) * | 1985-01-31 | 1986-04-22 | Ortho Pharmaceutical Corporation | Bursopoietin |
| IT1188646B (it) * | 1986-04-09 | 1988-01-20 | Ellem Ind Farmaceutica | Tripeptide ad attivita' immunostimolante |
| IT1196958B (it) * | 1986-07-10 | 1988-11-25 | Ellem Ind Farmaceutica | Derivato di timo attivo per via orale, procedimenti per la sua preparazione e relative composizioni farmaceutiche |
| DE68926178T2 (de) * | 1988-05-10 | 1996-11-28 | Alpha 1 Biomedicals Inc | Festphase-Verfahren zur Gewinnung von Thymosin-alpha-1 |
| HU201964B (en) * | 1989-01-13 | 1991-01-28 | Richter Gedeon Vegyeszet | Process for producing peptides inhibiting maturation of t-lymphocytes and activity of macrophages, as well as pharmaceutical compositions comprising same |
| CA2378480A1 (en) * | 1999-08-09 | 2001-02-15 | Tripep Ab | Pharmaceutical compositions containing tripeptides |
| US6258932B1 (en) * | 1999-08-09 | 2001-07-10 | Tripep Ab | Peptides that block viral infectivity and methods of use thereof |
| US6593455B2 (en) * | 2001-08-24 | 2003-07-15 | Tripep Ab | Tripeptide amides that block viral infectivity and methods of use thereof |
| US6455670B1 (en) * | 2001-09-06 | 2002-09-24 | Tripep Ab | Pentamer peptide amide, ALGPG-NH2, that inhibits viral infectivity and methods of use thereof |
| EP1436317A1 (de) * | 2001-09-19 | 2004-07-14 | Tripep Ab | Moleküle, die die virale infektivität hemmen, und verfahren zu deren anwendung |
| WO2004073703A1 (en) * | 2003-02-21 | 2004-09-02 | Tripep Ab | Glycinamide derivative for inhibiting hiv replication |
| US20050096319A1 (en) * | 2003-02-21 | 2005-05-05 | Balzarini Jan M.R. | Identification of compounds that inhibit replication of human immunodeficiency virus |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4098777A (en) * | 1977-03-14 | 1978-07-04 | Merck & Co., Inc. | Process for the preparation of pyroglutamyl-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn |
| FR2391994A1 (fr) * | 1977-05-25 | 1978-12-22 | Anvar | Nouveaux polypeptides a activite thymique ou a activite antagoniste et leurs procedes de synthese |
| SE446866B (sv) * | 1977-11-15 | 1986-10-13 | Sloan Kettering Inst Cancer | Sett att framstella en aktiv polypeptid med formaga att inducera differentiering av bade t-lymfocyter och komplementreceptor (cr?72+) b-lymfocyter |
| SE446867B (sv) * | 1977-11-15 | 1986-10-13 | Sloan Kettering Inst Cancer | Sett att framstella en polypeptid med formaga att inducera differentiering av t-lymfocyter men inte av komplementreceptor (cr?72+) b-lymfocyter |
| NZ189101A (en) * | 1977-12-08 | 1984-07-06 | Ortho Pharma Corp | Polypeptides having the ability to induce differentiation of both th-1+ t-lymphocytes and bu-1+ b-lymphocytes;pharmaceutical compositions |
-
1979
- 1979-03-14 US US06/020,159 patent/US4215112A/en not_active Expired - Lifetime
-
1980
- 1980-03-06 NZ NZ193063A patent/NZ193063A/en unknown
- 1980-03-11 AU AU56312/80A patent/AU531556B2/en not_active Ceased
- 1980-03-11 GR GR61411A patent/GR68039B/el unknown
- 1980-03-12 JP JP3046880A patent/JPS55143945A/ja active Pending
- 1980-03-12 PT PT70936A patent/PT70936B/pt unknown
- 1980-03-13 FI FI800780A patent/FI67692C/fi not_active IP Right Cessation
- 1980-03-13 ES ES489522A patent/ES8103027A1/es not_active Expired
- 1980-03-13 EP EP80300770A patent/EP0016611B1/de not_active Expired
- 1980-03-13 CA CA000347571A patent/CA1141375A/en not_active Expired
- 1980-03-13 IE IE514/80A patent/IE49289B1/en unknown
- 1980-03-13 IL IL59604A patent/IL59604A/xx unknown
- 1980-03-13 ZA ZA00801482A patent/ZA801482B/xx unknown
- 1980-03-13 AT AT80300770T patent/ATE4452T1/de not_active IP Right Cessation
- 1980-03-13 DK DK109280A patent/DK149092C/da active
- 1980-03-13 NO NO800723A patent/NO149997C/no unknown
- 1980-03-13 DE DE8080300770T patent/DE3064559D1/de not_active Expired
- 1980-03-14 YU YU698/80A patent/YU41914B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0016611B1 (de) | 1983-08-17 |
| PT70936A (en) | 1980-04-01 |
| AU5631280A (en) | 1980-09-18 |
| GR68039B (de) | 1981-10-27 |
| NZ193063A (en) | 1984-07-06 |
| DK109280A (da) | 1980-09-15 |
| CA1141375A (en) | 1983-02-15 |
| DK149092B (da) | 1986-01-20 |
| NO149997C (no) | 1984-08-01 |
| IL59604A (en) | 1983-02-23 |
| ES489522A0 (es) | 1981-02-16 |
| US4215112A (en) | 1980-07-29 |
| PT70936B (en) | 1981-06-24 |
| IL59604A0 (en) | 1980-06-30 |
| DE3064559D1 (en) | 1983-09-22 |
| ZA801482B (en) | 1981-10-28 |
| FI67692B (fi) | 1985-01-31 |
| IE49289B1 (en) | 1985-09-04 |
| YU41914B (en) | 1988-02-29 |
| NO149997B (no) | 1984-04-24 |
| JPS55143945A (en) | 1980-11-10 |
| FI800780A7 (fi) | 1980-09-15 |
| IE800514L (en) | 1980-09-14 |
| EP0016611A2 (de) | 1980-10-01 |
| EP0016611A3 (en) | 1981-01-07 |
| YU69880A (en) | 1983-02-28 |
| ES8103027A1 (es) | 1981-02-16 |
| NO800723L (no) | 1980-09-15 |
| AU531556B2 (en) | 1983-08-25 |
| FI67692C (fi) | 1985-05-10 |
| DK149092C (da) | 1986-06-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE4452T1 (de) | Tripeptide, verfahren zu ihrer herstellung, sie enthaltende therapeutische zusammensetzungen und methoden ihrer anwendung. | |
| US3926938A (en) | Synthesis of salmon calcitonin | |
| US4003884A (en) | Peptides having LH-RH/FSH-RH activity | |
| US4261886A (en) | Peptides having thymopoietin-like activity | |
| DE10075019I2 (de) | Neue Proteine mit TNF-Hemmender Wirkung und ihre Herstellung. | |
| ES2001274A6 (es) | Un metodo para preparar peptidos que tienen influencia sobre la funcion de la glandula pituitaria en seres humanos y otros animales | |
| NO932148L (no) | Fusjonspolypeptider | |
| DE3261304D1 (en) | Retro-inverso analogues of c-terminal penta and hexapeptides of substance p. | |
| EP0016612B1 (de) | Peptide mit Ubiquitin-ähnlicher Aktivität, Verfahren zu ihrer Herstellung, sie enthaltende therapeutische Zusammensetzungen und ihrer Anwendung | |
| HUT58765A (en) | Process for producing peptide compounds and pharmaceutical compositions containing them as active components | |
| EP0055113B1 (de) | Deka-, Undeka-, Dodeka- und Tridekapeptide mit thymischer Tätigkeit, Verfahren zu deren Herstellung und diese enthaltende Zusammensetzungen | |
| IE800743L (en) | Peptides having thymopoietin-like activity | |
| IE782423L (en) | Tetrapeptide segment | |
| IE893110L (en) | Peptides having t cell suppressor activity | |
| Rittel | Techniques for the synthesis of ACTH and MSH peptides and analogues | |
| Abiko et al. | Synthesis of [Phe (4F) 3] thymopoietin II and examination of its immunological effect on the impaired blastogenic response of T-lymphocytes of uremic patients | |
| Abiko | Syntheses and Structure-Activity Relationships of Thymopoietin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |