IL59604A - Tripeptides having the ability to induce differentiation of t-lymphocytes and b-lymphocytes,their preparation and pharmaceutical compositions containing them - Google Patents

Tripeptides having the ability to induce differentiation of t-lymphocytes and b-lymphocytes,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL59604A
IL59604A IL59604A IL5960480A IL59604A IL 59604 A IL59604 A IL 59604A IL 59604 A IL59604 A IL 59604A IL 5960480 A IL5960480 A IL 5960480A IL 59604 A IL59604 A IL 59604A
Authority
IL
Israel
Prior art keywords
lymphocytes
polypeptides
thr
ala
tripeptides
Prior art date
Application number
IL59604A
Other languages
English (en)
Other versions
IL59604A0 (en
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of IL59604A0 publication Critical patent/IL59604A0/xx
Publication of IL59604A publication Critical patent/IL59604A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/18—Thymus derived hormone or factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL59604A 1979-03-14 1980-03-13 Tripeptides having the ability to induce differentiation of t-lymphocytes and b-lymphocytes,their preparation and pharmaceutical compositions containing them IL59604A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/020,159 US4215112A (en) 1979-03-14 1979-03-14 Tripeptides and methods

Publications (2)

Publication Number Publication Date
IL59604A0 IL59604A0 (en) 1980-06-30
IL59604A true IL59604A (en) 1983-02-23

Family

ID=21797075

Family Applications (1)

Application Number Title Priority Date Filing Date
IL59604A IL59604A (en) 1979-03-14 1980-03-13 Tripeptides having the ability to induce differentiation of t-lymphocytes and b-lymphocytes,their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (1) US4215112A (xx)
EP (1) EP0016611B1 (xx)
JP (1) JPS55143945A (xx)
AT (1) ATE4452T1 (xx)
AU (1) AU531556B2 (xx)
CA (1) CA1141375A (xx)
DE (1) DE3064559D1 (xx)
DK (1) DK149092C (xx)
ES (1) ES489522A0 (xx)
FI (1) FI67692C (xx)
GR (1) GR68039B (xx)
IE (1) IE49289B1 (xx)
IL (1) IL59604A (xx)
NO (1) NO149997C (xx)
NZ (1) NZ193063A (xx)
PT (1) PT70936B (xx)
YU (1) YU41914B (xx)
ZA (1) ZA801482B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4298523A (en) * 1980-06-17 1981-11-03 Ortho Pharmaceutical Corporation Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R
US4369137A (en) * 1980-06-17 1983-01-18 Ortho Pharmaceutical Corporation N-Protected pentapeptides useful as intermediates in the preparation of thymopoietin pentapeptide
US4454065A (en) * 1982-05-18 1984-06-12 Smithkline Beckman Corporation Oligopeptide prodrugs
US4481191A (en) * 1983-03-30 1984-11-06 The Regents Of The University Of California Method for controlling blood pressure
US4683292A (en) * 1983-08-12 1987-07-28 Immunetech, Inc. Immunotherapeutic polypeptide agents which bind to lymphocyte immunoglobulin FC receptors
AU602483B2 (en) * 1985-01-18 1990-10-18 Immunetech Pharmaceuticals Immunoregulatory peptides
US4584284A (en) * 1985-01-31 1986-04-22 Ortho Pharmaceutical Corporation Bursopoietin
IT1188646B (it) * 1986-04-09 1988-01-20 Ellem Ind Farmaceutica Tripeptide ad attivita' immunostimolante
IT1196958B (it) * 1986-07-10 1988-11-25 Ellem Ind Farmaceutica Derivato di timo attivo per via orale, procedimenti per la sua preparazione e relative composizioni farmaceutiche
EP0341935B1 (en) * 1988-05-10 1996-04-10 Alpha-1 Biomedicals, Inc. A solid phase process for synthesizing Thymosin alpha 1
HU201964B (en) * 1989-01-13 1991-01-28 Richter Gedeon Vegyeszet Process for producing peptides inhibiting maturation of t-lymphocytes and activity of macrophages, as well as pharmaceutical compositions comprising same
PL354122A1 (en) * 1999-08-09 2003-12-29 Tripep Abtripep Ab Pharmaceutical compositions containing tripeptides
US6258932B1 (en) * 1999-08-09 2001-07-10 Tripep Ab Peptides that block viral infectivity and methods of use thereof
US6593455B2 (en) * 2001-08-24 2003-07-15 Tripep Ab Tripeptide amides that block viral infectivity and methods of use thereof
US6455670B1 (en) * 2001-09-06 2002-09-24 Tripep Ab Pentamer peptide amide, ALGPG-NH2, that inhibits viral infectivity and methods of use thereof
WO2003024995A1 (en) * 2001-09-19 2003-03-27 Tripep Ab Molecules that block viral infectivity and methods of use thereof
US20050096319A1 (en) * 2003-02-21 2005-05-05 Balzarini Jan M.R. Identification of compounds that inhibit replication of human immunodeficiency virus
US20040180893A1 (en) * 2003-02-21 2004-09-16 Balzarini Jan Maria Rene Identification of compounds that inhibit replication of human immunodeficiency virus

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4098777A (en) * 1977-03-14 1978-07-04 Merck & Co., Inc. Process for the preparation of pyroglutamyl-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn
FR2391994A1 (fr) * 1977-05-25 1978-12-22 Anvar Nouveaux polypeptides a activite thymique ou a activite antagoniste et leurs procedes de synthese
SE446867B (sv) * 1977-11-15 1986-10-13 Sloan Kettering Inst Cancer Sett att framstella en polypeptid med formaga att inducera differentiering av t-lymfocyter men inte av komplementreceptor (cr?72+) b-lymfocyter
SE446866B (sv) * 1977-11-15 1986-10-13 Sloan Kettering Inst Cancer Sett att framstella en aktiv polypeptid med formaga att inducera differentiering av bade t-lymfocyter och komplementreceptor (cr?72+) b-lymfocyter
NZ189101A (en) * 1977-12-08 1984-07-06 Ortho Pharma Corp Polypeptides having the ability to induce differentiation of both th-1+ t-lymphocytes and bu-1+ b-lymphocytes;pharmaceutical compositions

Also Published As

Publication number Publication date
PT70936B (en) 1981-06-24
IE800514L (en) 1980-09-14
DK109280A (da) 1980-09-15
IE49289B1 (en) 1985-09-04
EP0016611A2 (en) 1980-10-01
JPS55143945A (en) 1980-11-10
DK149092B (da) 1986-01-20
EP0016611A3 (en) 1981-01-07
IL59604A0 (en) 1980-06-30
NO800723L (no) 1980-09-15
FI800780A (fi) 1980-09-15
ATE4452T1 (de) 1983-09-15
ZA801482B (en) 1981-10-28
ES8103027A1 (es) 1981-02-16
FI67692B (fi) 1985-01-31
YU69880A (en) 1983-02-28
DE3064559D1 (en) 1983-09-22
ES489522A0 (es) 1981-02-16
AU531556B2 (en) 1983-08-25
CA1141375A (en) 1983-02-15
YU41914B (en) 1988-02-29
GR68039B (xx) 1981-10-27
NO149997B (no) 1984-04-24
NO149997C (no) 1984-08-01
DK149092C (da) 1986-06-16
AU5631280A (en) 1980-09-18
EP0016611B1 (en) 1983-08-17
US4215112A (en) 1980-07-29
PT70936A (en) 1980-04-01
NZ193063A (en) 1984-07-06
FI67692C (fi) 1985-05-10

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