FI66598C - Foerfarande foer framstaellning av terapeutiskt anvaendbara sapetersyraestrar av n-(hydroxialkyl)pyridinkarboxamidderiv at - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara sapetersyraestrar av n-(hydroxialkyl)pyridinkarboxamidderiv at Download PDF

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Publication number
FI66598C
FI66598C FI771024A FI771024A FI66598C FI 66598 C FI66598 C FI 66598C FI 771024 A FI771024 A FI 771024A FI 771024 A FI771024 A FI 771024A FI 66598 C FI66598 C FI 66598C
Authority
FI
Finland
Prior art keywords
compound
solution
nitric acid
coronary
effect
Prior art date
Application number
FI771024A
Other languages
English (en)
Finnish (fi)
Other versions
FI66598B (fi
FI771024A (de
Inventor
Hiroyuki Nagano
Takashi Mori
Sakae Takaku
Isao Matsunaga
Tatsuo Kujirai
Toshichika Ogasawara
Shigeru Sugano
Minoru Shindo
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP51036101A external-priority patent/JPS5817463B2/ja
Priority claimed from JP8245876A external-priority patent/JPS6052685B2/ja
Priority claimed from JP8352276A external-priority patent/JPS539775A/ja
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of FI771024A publication Critical patent/FI771024A/fi
Application granted granted Critical
Publication of FI66598B publication Critical patent/FI66598B/fi
Publication of FI66598C publication Critical patent/FI66598C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
FI771024A 1976-04-02 1977-04-01 Foerfarande foer framstaellning av terapeutiskt anvaendbara sapetersyraestrar av n-(hydroxialkyl)pyridinkarboxamidderiv at FI66598C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP51036101A JPS5817463B2 (ja) 1976-04-02 1976-04-02 ニコチン酸アミド誘導体
JP3610176 1976-04-02
JP8245876A JPS6052685B2 (ja) 1976-07-13 1976-07-13 循環器疾患治療剤
JP8245876 1976-07-13
JP8352276A JPS539775A (en) 1976-07-15 1976-07-15 Pyridine derivatives and their preparation
JP8352276 1976-07-15

Publications (3)

Publication Number Publication Date
FI771024A FI771024A (de) 1977-10-03
FI66598B FI66598B (fi) 1984-07-31
FI66598C true FI66598C (fi) 1984-11-12

Family

ID=27288973

Family Applications (1)

Application Number Title Priority Date Filing Date
FI771024A FI66598C (fi) 1976-04-02 1977-04-01 Foerfarande foer framstaellning av terapeutiskt anvaendbara sapetersyraestrar av n-(hydroxialkyl)pyridinkarboxamidderiv at

Country Status (13)

Country Link
AR (2) AR217423A1 (de)
AT (1) AT360532B (de)
AU (1) AU509591B2 (de)
CA (1) CA1088944A (de)
CH (1) CH633535A5 (de)
DE (1) DE2714713C3 (de)
DK (1) DK145608C (de)
ES (2) ES457421A1 (de)
FI (1) FI66598C (de)
FR (1) FR2346334A1 (de)
MX (1) MX5534E (de)
NL (2) NL176674C (de)
SE (1) SE436029B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0653658B2 (ja) * 1984-12-17 1994-07-20 中外製薬株式会社 安定な錠剤の製造法
EP0223811A1 (de) * 1985-05-22 1987-06-03 Beecham Group Plc Verwendung von nicorandil oder pinacidil zur behandlung von periphären gefässkrankheiten
WO1989010757A1 (en) * 1988-05-10 1989-11-16 Leo Pharmaceutical Products Ltd. A/S (Løvens Kemis New ophthalmic preparation for treating glaucoma
US4973565A (en) * 1989-07-17 1990-11-27 Corning Incorporated Fluoroborosilicate glass and clad article
ZA91291B (en) * 1990-01-16 1991-09-25 Hoechst Ag Di(nitroxyalkyl)amides of pyridine-2,4-and-2,5-dicarboxylic acids,a process for the preparation thereof,and the use thereof
US6417207B1 (en) 1999-05-12 2002-07-09 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
US20110082177A1 (en) * 2008-07-01 2011-04-07 Jerzy Gebicki N'-nitroxyalkylnicotinamides for the treatment of cardiovascular diseases
IT1403890B1 (it) 2010-12-28 2013-11-08 Procos Spa Processo per la produzione di nicorandil

Also Published As

Publication number Publication date
NL7703624A (nl) 1977-10-04
DK145608C (da) 1983-07-11
AU2353277A (en) 1978-09-28
NL176674C (nl) 1985-05-17
FR2346334B1 (de) 1980-02-01
AU509591B2 (en) 1980-05-15
ATA235077A (de) 1980-06-15
AR220907A1 (es) 1980-12-15
DE2714713A1 (de) 1977-10-20
FR2346334A1 (fr) 1977-10-28
DE2714713C3 (de) 1980-10-16
ES468462A1 (es) 1979-10-01
SE436029B (sv) 1984-11-05
DK128277A (da) 1977-10-03
NL930042I2 (nl) 1993-09-16
ES457421A1 (es) 1978-11-16
FI66598B (fi) 1984-07-31
FI771024A (de) 1977-10-03
CA1088944A (en) 1980-11-04
DE2714713B2 (de) 1980-02-21
NL176674B (nl) 1984-12-17
DK145608B (da) 1982-12-27
AR217423A1 (es) 1980-03-31
AT360532B (de) 1981-01-12
SE7703868L (sv) 1977-10-03
NL930042I1 (nl) 1993-08-02
MX5534E (es) 1983-09-27
CH633535A5 (en) 1982-12-15

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Legal Events

Date Code Title Description
MA Patent expired
MA Patent expired

Owner name: CHUGAI SEIYAKU KABUSHIKI KAISHA