FI64938C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensoxa- och bensotiadiazolyl-1,4-dihydropyridinderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensoxa- och bensotiadiazolyl-1,4-dihydropyridinderivat Download PDF

Info

Publication number
FI64938C
FI64938C FI781867A FI781867A FI64938C FI 64938 C FI64938 C FI 64938C FI 781867 A FI781867 A FI 781867A FI 781867 A FI781867 A FI 781867A FI 64938 C FI64938 C FI 64938C
Authority
FI
Finland
Prior art keywords
formula
therapeutic
procedure
derivatives
reacted
Prior art date
Application number
FI781867A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI781867A (fi
FI64938B (fi
Inventor
Peter Neumann
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI781867A publication Critical patent/FI781867A/fi
Application granted granted Critical
Publication of FI64938B publication Critical patent/FI64938B/fi
Publication of FI64938C publication Critical patent/FI64938C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI781867A 1977-06-20 1978-06-12 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensoxa- och bensotiadiazolyl-1,4-dihydropyridinderivat FI64938C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH752077 1977-06-20
CH752077 1977-06-20
CH286578 1978-03-16
CH286578 1978-03-16

Publications (3)

Publication Number Publication Date
FI781867A FI781867A (fi) 1978-12-21
FI64938B FI64938B (fi) 1983-10-31
FI64938C true FI64938C (fi) 1984-02-10

Family

ID=25691589

Family Applications (1)

Application Number Title Priority Date Filing Date
FI781867A FI64938C (fi) 1977-06-20 1978-06-12 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensoxa- och bensotiadiazolyl-1,4-dihydropyridinderivat

Country Status (20)

Country Link
EP (1) EP0000150B1 (ja)
JP (1) JPS54103876A (ja)
AT (1) AT376220B (ja)
AU (1) AU524000B2 (ja)
CA (1) CA1105463A (ja)
CY (1) CY1239A (ja)
DE (1) DE2860708D1 (ja)
DK (1) DK149855C (ja)
ES (1) ES470917A1 (ja)
FI (1) FI64938C (ja)
HK (1) HK65184A (ja)
IE (1) IE47212B1 (ja)
IL (1) IL54948A (ja)
IT (1) IT1105364B (ja)
LU (1) LU88342I2 (ja)
MY (1) MY8500041A (ja)
NL (1) NL930126I2 (ja)
NZ (1) NZ187617A (ja)
PT (1) PT68191A (ja)
SG (1) SG20584G (ja)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH639659A5 (de) * 1978-12-18 1983-11-30 Sandoz Ag Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung.
DK525179A (da) * 1978-12-18 1980-06-19 Sandoz Ag Fremgangsmaade til fremstilling af benzoxadiazoler og benzothiazoler
BE886259A (fr) * 1979-11-23 1981-05-20 Sandoz Sa Nouveaux medicament a base de derives de la 1,4-dihydropyridine, pour le traitement de l'insuffisance cerebrovasculaire ou a action spamolytique
CH655658B (ja) * 1980-09-18 1986-05-15
FI813460L (fi) * 1980-11-10 1982-05-11 Sandoz Ag Nya 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-pyridinderivat deras framstaellningsfoerfarande och dessa innehaollande farmaceutiska kompositioner
EP0080220B1 (en) * 1981-11-17 1986-02-19 FISONS plc Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
ZA83959B (en) * 1982-03-10 1984-09-26 Sandoz Ltd 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
FR2528431B1 (fr) * 1982-06-15 1986-01-10 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
FR2554109A1 (fr) * 1983-11-01 1985-05-03 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation en therapeutique comme medicaments
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
HU198844B (en) * 1984-06-14 1989-12-28 Sandoz Ag Process for producing new galenic pharmaceutical composition ensuring retarded release of active ingredient
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
GB8428552D0 (en) * 1984-11-12 1984-12-19 Sandoz Ltd Organic compounds
GB8616047D0 (en) * 1986-07-01 1986-08-06 Sandoz Ltd A 1 4-dihydropyridine derivatives
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof

Also Published As

Publication number Publication date
FI781867A (fi) 1978-12-21
AU524000B2 (en) 1982-08-26
EP0000150B1 (en) 1981-05-20
JPS6360755B2 (ja) 1988-11-25
CY1239A (en) 1984-06-29
LU88342I2 (fr) 1994-05-04
DK149855B (da) 1986-10-13
NZ187617A (en) 1980-12-19
NL930126I2 (nl) 1995-02-16
PT68191A (fr) 1978-07-01
FI64938B (fi) 1983-10-31
DK149855C (da) 1987-04-21
AT376220B (de) 1984-10-25
AU3725278A (en) 1980-01-03
SG20584G (en) 1985-03-08
IT1105364B (it) 1985-10-28
IL54948A0 (en) 1978-08-31
IE781231L (en) 1978-12-20
HK65184A (en) 1984-08-31
IE47212B1 (en) 1984-01-25
ES470917A1 (es) 1979-10-01
DE2860708D1 (en) 1981-08-27
DK262578A (da) 1978-12-21
ATA443178A (de) 1984-03-15
NL930126I1 (nl) 1993-11-01
CA1105463A (en) 1981-07-21
IT7849939A0 (it) 1978-06-19
EP0000150A1 (en) 1979-01-10
IL54948A (en) 1982-01-31
MY8500041A (en) 1985-12-31
JPS54103876A (en) 1979-08-15

Similar Documents

Publication Publication Date Title
FI64938C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensoxa- och bensotiadiazolyl-1,4-dihydropyridinderivat
US4466972A (en) Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them
US4921863A (en) Cyclic amine derivatives
NL193066C (nl) Methyl,isopropyl-4-(2,1,3-benzoxadiazool-4-yl)-2,6-dimethyl-1,4-dihydro pyridine-3,5-dicarboxylaat en farmaceutisch preparaat dat deze verbinding bevat.
CS228506B2 (en) Method for the production of optical active ester of 1,4-dihydropyridincarboxyl acid
CH633266A5 (en) Process for preparing 1,4-dihydropyridine compounds
SE446265B (sv) 2-metyl-1,4-dihydropyridinforeningar
US4808718A (en) Fused polycyclic and bridged compounds useful as calcium channel blockers
US4753936A (en) Circulation-active substituted 1,4-dihydropyridine-3-carboxylic acid piperazides
US4069322A (en) Pro-drugs for the improved delivery of certain selected anti-inflammatory steroids
Taylor et al. 2-(2-Aryl-2-oxoethylidene)-1, 2, 3, 4-tetrahydropyridines. Novel isomers of 1, 4-dihydropyridine calcium channel blockers
EP0220653B1 (en) 3-aminocarbonyl-1,4-dihydropyridine-5-carboxylic acid compounds, process for preparation and use thereof, and pharmaceutical composition containing the same
JP2005505621A5 (ja)
JPH01319479A (ja) ５―アミノメチル―２―フラノメタノールの新規な誘導体、その製造及び使用
US4562203A (en) Rifamycins derivatives and preparation and pharmaceutical compositions thereof
US4180581A (en) N-9,10-dihydrolysergyl-m-aminobenzoic acid amide derivative
EP0106276B1 (en) 1,4-dihydropyridine derivatives
EP0093945A2 (en) 1,4-Dihydropyridine derivatives
EP0160451B1 (en) Dihydropyridine-3,5-dicarboxylic acid ester derivative isomers, their preparation, and pharmaceutical compositions containing them
EP0039919B1 (en) Benzoxazole and benzothiazole derivatives with anti-allergic activity
US4659707A (en) Aminoacyl derivatives of 4,9-dihydro-10H-pyrido[3,2-b]thieno[3,2-e][1,4]diazepinone and of 4,9-dihydro-10H-pyrido[3,2-b]thieno[3,4-e][1,4]diazepinone, their preparation and pharmaceutical compositions containing them
US4138482A (en) 3-Cyano-N-(N,N-dimethylaminopropyl)-iminodibenzyl and salts thereof
US4567271A (en) Benzoxadiazoles and benzothiadiazoles
US4491581A (en) 4-(2,1,3-Benzoxadiazol-4-yl)-1,4-dihydropyridazine derivatives, their production and pharmaceutical compositions
JPH0155268B2 (ja)

Legal Events

Date Code Title Description
MA Patent expired
ND Supplementary protection certificate (spc) granted
SPCG Supplementary protection certificate granted

Spc suppl protection certif: L45

Extension date: 20030612

PC Transfer of assignment of patent

Owner name: NOVARTIS AG

MA Patent expired

Owner name: NOVARTIS AG