DE2860708D1 - Dihydropyridine derivatives, process for their production and pharmaceutical compositions containing them. - Google Patents

Dihydropyridine derivatives, process for their production and pharmaceutical compositions containing them.

Info

Publication number
DE2860708D1
DE2860708D1 DE7878100165T DE2860708T DE2860708D1 DE 2860708 D1 DE2860708 D1 DE 2860708D1 DE 7878100165 T DE7878100165 T DE 7878100165T DE 2860708 T DE2860708 T DE 2860708T DE 2860708 D1 DE2860708 D1 DE 2860708D1
Authority
DE
Germany
Prior art keywords
production
pharmaceutical compositions
compositions containing
dihydropyridine derivatives
dihydropyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7878100165T
Other languages
English (en)
Inventor
Peter Dr Neumann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of DE2860708D1 publication Critical patent/DE2860708D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE7878100165T 1977-06-20 1978-06-15 Dihydropyridine derivatives, process for their production and pharmaceutical compositions containing them. Expired DE2860708D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH752077 1977-06-20
CH286578 1978-03-16

Publications (1)

Publication Number Publication Date
DE2860708D1 true DE2860708D1 (en) 1981-08-27

Family

ID=25691589

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7878100165T Expired DE2860708D1 (en) 1977-06-20 1978-06-15 Dihydropyridine derivatives, process for their production and pharmaceutical compositions containing them.

Country Status (20)

Country Link
EP (1) EP0000150B1 (de)
JP (1) JPS54103876A (de)
AT (1) AT376220B (de)
AU (1) AU524000B2 (de)
CA (1) CA1105463A (de)
CY (1) CY1239A (de)
DE (1) DE2860708D1 (de)
DK (1) DK149855C (de)
ES (1) ES470917A1 (de)
FI (1) FI64938C (de)
HK (1) HK65184A (de)
IE (1) IE47212B1 (de)
IL (1) IL54948A (de)
IT (1) IT1105364B (de)
LU (1) LU88342I2 (de)
MY (1) MY8500041A (de)
NL (1) NL930126I2 (de)
NZ (1) NZ187617A (de)
PT (1) PT68191A (de)
SG (1) SG20584G (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH639659A5 (de) * 1978-12-18 1983-11-30 Sandoz Ag Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung.
DK525179A (da) * 1978-12-18 1980-06-19 Sandoz Ag Fremgangsmaade til fremstilling af benzoxadiazoler og benzothiazoler
BE886259A (fr) * 1979-11-23 1981-05-20 Sandoz Sa Nouveaux medicament a base de derives de la 1,4-dihydropyridine, pour le traitement de l'insuffisance cerebrovasculaire ou a action spamolytique
CH655658B (de) * 1980-09-18 1986-05-15
FI813460L (fi) * 1980-11-10 1982-05-11 Sandoz Ag Nya 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-pyridinderivat deras framstaellningsfoerfarande och dessa innehaollande farmaceutiska kompositioner
EP0080220B1 (de) * 1981-11-17 1986-02-19 FISONS plc Dihydropyridine, Verfahren zu ihrer Herstellung, ihre Zusammensetzungen und ihre Verwendung als Arzneimittel
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
ZA83959B (en) * 1982-03-10 1984-09-26 Sandoz Ltd 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
FR2528431B1 (fr) * 1982-06-15 1986-01-10 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
FR2554109A1 (fr) * 1983-11-01 1985-05-03 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation en therapeutique comme medicaments
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
HU198844B (en) * 1984-06-14 1989-12-28 Sandoz Ag Process for producing new galenic pharmaceutical composition ensuring retarded release of active ingredient
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
GB8428552D0 (en) * 1984-11-12 1984-12-19 Sandoz Ltd Organic compounds
GB8616047D0 (en) * 1986-07-01 1986-08-06 Sandoz Ltd A 1 4-dihydropyridine derivatives
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof

Also Published As

Publication number Publication date
FI781867A (fi) 1978-12-21
AU524000B2 (en) 1982-08-26
EP0000150B1 (de) 1981-05-20
JPS6360755B2 (de) 1988-11-25
CY1239A (en) 1984-06-29
LU88342I2 (fr) 1994-05-04
DK149855B (da) 1986-10-13
FI64938C (fi) 1984-02-10
NZ187617A (en) 1980-12-19
NL930126I2 (nl) 1995-02-16
PT68191A (fr) 1978-07-01
FI64938B (fi) 1983-10-31
DK149855C (da) 1987-04-21
AT376220B (de) 1984-10-25
AU3725278A (en) 1980-01-03
SG20584G (en) 1985-03-08
IT1105364B (it) 1985-10-28
IL54948A0 (en) 1978-08-31
IE781231L (en) 1978-12-20
HK65184A (en) 1984-08-31
IE47212B1 (en) 1984-01-25
ES470917A1 (es) 1979-10-01
DK262578A (da) 1978-12-21
ATA443178A (de) 1984-03-15
NL930126I1 (nl) 1993-11-01
CA1105463A (en) 1981-07-21
IT7849939A0 (it) 1978-06-19
EP0000150A1 (de) 1979-01-10
IL54948A (en) 1982-01-31
MY8500041A (en) 1985-12-31
JPS54103876A (en) 1979-08-15

Similar Documents

Publication Publication Date Title
DE2860900D1 (en) Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them
IL64345A (en) Substituted phenoxypropanolamine derivatives,process for the production thereof and pharmaceutical compositions containing the same
IL54429A (en) 2-aminoalkylene dihydropyridine compounds,their production and pharmaceutical compositions containing them
MY8500040A (en) Propenylamines, processes for their production and pharmaceutical compositions containing them
IL55236A (en) Prostaglandin i2 derivatives,process for their production and pharmaceutical compositions containing them
DE2860708D1 (en) Dihydropyridine derivatives, process for their production and pharmaceutical compositions containing them.
IL55109A (en) 1-acyl-2-cyanoaziridines,process for their preparation and pharmaceutical compositions containing them
DE2861361D1 (en) 1-n-acylated-4-o-glycosyl-6-o-glycosyl-1,3-diaminocyclitol derivatives, process for their preparation and pharmaceutical compositions containing them
DE2861482D1 (en) Pyrazino-benzoxazepine and -benzthiazepine derivatives, processes for their production and pharmaceutical compositions containing them
IL56105A0 (en) New 1-n-aryl-1,4-dihydropyridines, their production and pharmaceutical compositions containing them
IL55170A (en) Indole derivatives,their production and pharmaceutical compositions containing them
IL54069A0 (en) New 20,21-dinoreburnamenine derivatives,process for preparing them and pharmaceutical compositions
IL55862A0 (en) Novel 6-oxygenated-3,20-dioxo-pregnane derivatives, process for the preparation thereof, and pharmaceutical compositionss containing them
IL54105A (en) 2-acylamino-4-amino-5-benzylpyrimidine derivatives,their production and pharmaceutical compositions containing them
DE2861767D1 (en) Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them
IL53901A0 (en) New ergot derivatives, their production and pharmaceutical compositions containing them
IL54718A (en) 17beta-hydroxy delta4-androsten-3-ones,process for their manufacture and pharmaceutical compositions containing them
DE2860709D1 (en) 1-substituted aminoindolines, process for their production and pharmaceutical compositions containing them
IL54736A0 (en) 4-hydroxythiazolidine-2-thione derivatives, a process for their preparation and pharmaceutical compositions containing them
IL55139A (en) Substituted 2-cyclopropyl-chromones,process for their preparation and pharmaceutical compositions containing them
ZA782432B (en) 2-benzyl-perhydroazepines,process for their preparation and pharmaceutical compositions containing them
DE2861670D1 (en) Antibiotic no. 2-200, process for its production and pharmaceutical compositions containing antibiotic no. 2-200
IL55651A0 (en) Thienobenzazepine derivatives,their production and pharmaceutical compositions containing them
IL54614A0 (en) New pyrandoquinoline derivatives, their production and pharmaceutical compositions containing them
IL54342A0 (en) New ergot derivatives, their production and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SANDOZ-PATENT-GMBH, 7850 LOERRACH, DE

V448 Application of spc

Free format text: PRODUCT NAME: ISRADIPIN; REGISTRATION NO/DATE: 17474.00.00, 17475.00.00, 22629.00.00; 19901029

Spc suppl protection certif: 193 75 088

Filing date: 19930630

V457 Spc granted

Free format text: PRODUCT NAME: ISRADIPIN; REGISTRATION NO/DATE: 17474.00.00, 17475.00.00, 22629.00.00; 19901029

Spc suppl protection certif: 193 75 088

Filing date: 19930630

8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS AG, BASEL, CH

8328 Change in the person/name/address of the agent

Free format text: SPOTT WEINMILLER & PARTNER, 80336 MUENCHEN

V464 Spc expired

Free format text: PRODUCT NAME: ISRADIPIN; REGISTRATION NO/DATE: 17474.00.00, 17475.00.00, 22629.00.00; 19901029

Spc suppl protection certif: 193 75 088

Filing date: 19930630