FI64143C - Foerfarande foer framstaellning av en ny terapeutiskt anvaendbar 3-fluor-6-(4-metyl-1-piperazinyl)-morfantridin - Google Patents

Foerfarande foer framstaellning av en ny terapeutiskt anvaendbar 3-fluor-6-(4-metyl-1-piperazinyl)-morfantridin Download PDF

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Publication number
FI64143C
FI64143C FI773273A FI773273A FI64143C FI 64143 C FI64143 C FI 64143C FI 773273 A FI773273 A FI 773273A FI 773273 A FI773273 A FI 773273A FI 64143 C FI64143 C FI 64143C
Authority
FI
Finland
Prior art keywords
compound
formula
fluoro
piperazinyl
therapeutic
Prior art date
Application number
FI773273A
Other languages
English (en)
Finnish (fi)
Other versions
FI64143B (fi
FI773273A (fi
Inventor
Fritz Hunziker
Rudolf Fischer
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI773273A publication Critical patent/FI773273A/fi
Application granted granted Critical
Publication of FI64143B publication Critical patent/FI64143B/fi
Publication of FI64143C publication Critical patent/FI64143C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI773273A 1976-11-10 1977-11-01 Foerfarande foer framstaellning av en ny terapeutiskt anvaendbar 3-fluor-6-(4-metyl-1-piperazinyl)-morfantridin FI64143C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1415776 1976-11-10
CH1415776A CH624682A5 (xx) 1976-11-10 1976-11-10

Publications (3)

Publication Number Publication Date
FI773273A FI773273A (fi) 1978-05-11
FI64143B FI64143B (fi) 1983-06-30
FI64143C true FI64143C (fi) 1983-10-10

Family

ID=4398460

Family Applications (1)

Application Number Title Priority Date Filing Date
FI773273A FI64143C (fi) 1976-11-10 1977-11-01 Foerfarande foer framstaellning av en ny terapeutiskt anvaendbar 3-fluor-6-(4-metyl-1-piperazinyl)-morfantridin

Country Status (26)

Country Link
US (1) US4308207A (xx)
JP (1) JPS5929076B2 (xx)
AT (1) AT366682B (xx)
AU (1) AU517829B2 (xx)
BE (1) BE860613A (xx)
CA (1) CA1086315A (xx)
CH (1) CH624682A5 (xx)
CY (1) CY1269A (xx)
DE (1) DE2748920C2 (xx)
DK (1) DK140724B (xx)
ES (1) ES463971A1 (xx)
FI (1) FI64143C (xx)
FR (1) FR2370745A1 (xx)
GB (2) GB1592329A (xx)
HK (1) HK32282A (xx)
IE (1) IE46262B1 (xx)
IL (1) IL53332A (xx)
KE (1) KE3472A (xx)
MY (1) MY8400056A (xx)
NL (1) NL175297C (xx)
NZ (2) NZ185642A (xx)
PH (1) PH13515A (xx)
PT (1) PT67247B (xx)
SE (1) SE435510B (xx)
SG (1) SG66584G (xx)
SU (1) SU686616A1 (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3402060A1 (de) * 1984-01-21 1985-08-01 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte 5,11-dihydro-6h-dibenz(b,e)azepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
EP0552245A1 (en) * 1990-10-10 1993-07-28 Schering Corporation Bis-benzo cyclohepta piperidylidene, piperidine and piperazine compounds, compositions and methods of use
BR0314108A (pt) * 2002-09-18 2006-04-25 Fmc Corp derivados tricìclios inseticidas
US20050250767A1 (en) * 2003-01-23 2005-11-10 Weiner David M Use of N-desmethylclozapine to treat human neuropsychiatric disease
AU2004206931A1 (en) * 2003-01-23 2004-08-05 Acadia Pharmaceuticals Inc. Use of N-desmethylclozapine to treat human neuropsychiatric disease
US20050085463A1 (en) * 2003-01-23 2005-04-21 Weiner David M. Use of N-desmethylclozapine to treat human neuropsychiatric disease
DE602004020263D1 (de) * 2003-12-22 2009-05-07 Acadia Pharm Inc Amino-substituierte diaryläa,dücyclohepten- analoga als muscarinische agonisten und verfahren zur behandlung von neuropsychiatrischen erkrankungen
JP2007536216A (ja) * 2004-04-01 2007-12-13 アカディア ファーマシューティカルズ，インコーポレーテッド 固体ｎ−デスメチルクロザピンおよびその結晶形を合成および単離する方法
US20070105836A1 (en) * 2005-10-31 2007-05-10 Lars Pettersson Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL140242B (nl) * 1963-03-01 1973-11-15 Wander Ag Dr A Werkwijze voor het bereiden van op de 11-plaats door een basische groep gesubstitueerde dibenz (b.f.)(1.4) oxazepinen.
US3389139A (en) * 1963-06-14 1968-06-18 Wander Ag Dr A 6-homopiperazino and piperazinomorphanthridines
GB1006156A (en) * 1963-06-14 1965-09-29 Wander Ag Dr A 6-basic substituted morphanthridines
US3539573A (en) * 1967-03-22 1970-11-10 Jean Schmutz 11-basic substituted dibenzodiazepines and dibenzothiazepines
US3962248A (en) * 1972-04-04 1976-06-08 Sandoz, Inc. Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines
CH601287A5 (xx) * 1975-08-06 1978-07-14 Sandoz Ag

Also Published As

Publication number Publication date
DK485677A (xx) 1978-05-11
ES463971A1 (es) 1978-12-01
BE860613A (fr) 1978-05-08
DE2748920A1 (de) 1978-05-11
SE435510B (sv) 1984-10-01
JPS5359686A (en) 1978-05-29
SU686616A3 (ru) 1979-09-15
NL7712171A (nl) 1978-05-12
NZ185642A (en) 1980-09-12
NL175297B (nl) 1984-05-16
CA1086315A (en) 1980-09-23
CH624682A5 (xx) 1981-08-14
DK140724B (da) 1979-11-05
JPS5929076B2 (ja) 1984-07-18
AU3046777A (en) 1979-05-17
FI64143B (fi) 1983-06-30
US4308207A (en) 1981-12-29
NZ191043A (en) 1980-09-12
PT67247A (en) 1977-12-01
FR2370745A1 (fr) 1978-06-09
IL53332A0 (en) 1978-01-31
KE3472A (en) 1984-11-09
AU517829B2 (en) 1981-08-27
SE7712387L (sv) 1978-05-11
AT366682B (de) 1982-04-26
SU686616A1 (en) 1979-09-15
HK32282A (en) 1982-07-23
NL175297C (nl) 1984-10-16
IE46262B1 (en) 1983-04-20
DK140724C (xx) 1980-03-31
SG66584G (en) 1985-03-15
GB1592329A (en) 1981-07-08
GB1592330A (en) 1981-07-08
FI773273A (fi) 1978-05-11
DE2748920C2 (de) 1982-12-02
FR2370745B1 (xx) 1980-08-22
MY8400056A (en) 1984-12-31
IE46262L (en) 1978-05-10
CY1269A (en) 1984-11-23
PH13515A (en) 1980-06-03
IL53332A (en) 1981-11-30
ATA799177A (de) 1981-09-15
PT67247B (en) 1979-11-12

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MM Patent lapsed

Owner name: SANDOZ AG