FI63033C - Foerfarande foer framstaellning av anxiolytiska tranquilliserande sedativa och/eller neuroleptiska substituerade 1-piperazinyl-4h-s-triazolo(3,4-c)tieno(2,3-e)-1,4-diazepiner - Google Patents

Foerfarande foer framstaellning av anxiolytiska tranquilliserande sedativa och/eller neuroleptiska substituerade 1-piperazinyl-4h-s-triazolo(3,4-c)tieno(2,3-e)-1,4-diazepiner Download PDF

Info

Publication number
FI63033C
FI63033C FI782025A FI782025A FI63033C FI 63033 C FI63033 C FI 63033C FI 782025 A FI782025 A FI 782025A FI 782025 A FI782025 A FI 782025A FI 63033 C FI63033 C FI 63033C
Authority
FI
Finland
Prior art keywords
triazolo
thieno
piperazinyl
formula
compounds
Prior art date
Application number
FI782025A
Other languages
English (en)
Finnish (fi)
Other versions
FI782025A (fi
FI63033B (fi
Inventor
Karl-Heinz Weber
Adolf Langbein
Claus Schneider
Erich Lehr
Karin Boeke
Franz Josef Kuhn
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19772732943 external-priority patent/DE2732943A1/de
Priority claimed from DE19772732921 external-priority patent/DE2732921A1/de
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of FI782025A publication Critical patent/FI782025A/fi
Publication of FI63033B publication Critical patent/FI63033B/fi
Application granted granted Critical
Publication of FI63033C publication Critical patent/FI63033C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI782025A 1977-07-21 1978-06-26 Foerfarande foer framstaellning av anxiolytiska tranquilliserande sedativa och/eller neuroleptiska substituerade 1-piperazinyl-4h-s-triazolo(3,4-c)tieno(2,3-e)-1,4-diazepiner FI63033C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19772732943 DE2732943A1 (de) 1977-07-21 1977-07-21 Neue substituierte 1-piperazinyl- 4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE2732921 1977-07-21
DE2732943 1977-07-21
DE19772732921 DE2732921A1 (de) 1977-07-21 1977-07-21 Neue substituierte 1-acyl-piperidino- bzw. -piperazino-4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4- diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen

Publications (3)

Publication Number Publication Date
FI782025A FI782025A (fi) 1979-01-22
FI63033B FI63033B (fi) 1982-12-31
FI63033C true FI63033C (fi) 1983-04-11

Family

ID=25772369

Family Applications (1)

Application Number Title Priority Date Filing Date
FI782025A FI63033C (fi) 1977-07-21 1978-06-26 Foerfarande foer framstaellning av anxiolytiska tranquilliserande sedativa och/eller neuroleptiska substituerade 1-piperazinyl-4h-s-triazolo(3,4-c)tieno(2,3-e)-1,4-diazepiner

Country Status (30)

Country Link
US (1) US4180573A (da)
EP (1) EP0000479B1 (da)
JP (1) JPS5422395A (da)
AT (1) AT363949B (da)
AU (1) AU515885B2 (da)
CA (1) CA1087182A (da)
CH (1) CH642374A5 (da)
CS (1) CS209897B2 (da)
DD (1) DD137934A5 (da)
DE (1) DE2860404D1 (da)
DK (1) DK150306C (da)
ES (2) ES471886A1 (da)
FI (1) FI63033C (da)
FR (1) FR2398070A1 (da)
GB (1) GB2001972B (da)
GR (1) GR65022B (da)
HU (1) HU176485B (da)
IE (1) IE47336B1 (da)
IL (1) IL55169A (da)
IT (1) IT1107490B (da)
LU (1) LU80002A1 (da)
NL (1) NL7807762A (da)
NO (1) NO149889C (da)
NZ (1) NZ187915A (da)
PH (1) PH14236A (da)
PL (1) PL115061B1 (da)
PT (1) PT68330A (da)
RO (1) RO75609A (da)
SE (1) SE439920B (da)
SU (2) SU725564A3 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2830782A1 (de) * 1978-07-13 1980-01-24 Boehringer Sohn Ingelheim Neue substituierte 4h-s-triazolo eckige klammer auf 3,4c eckige klammer zu thieno eckige klammer auf 2,3e eckige klammer zu 1,4-diazepine, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
ES2037013T3 (es) * 1986-01-21 1993-06-16 Boehringer Ingelheim Kg Procedimiento para preparar tieno-1,4-diazepinas.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12303A (en) * 1973-02-08 1979-01-16 Hoffmann La Roche Thienotriazolodiazepine derivatives
AT338799B (de) * 1974-03-02 1977-09-12 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer substituierter 6-aryl-4h-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine und ihrer salze
US3894025A (en) * 1974-03-21 1975-07-08 Upjohn Co 1-Piperazino-6-phenyl-4H-s-triazolo{8 4,3-a{9 {8 1,4{9 -benzodiazepine compounds
JPS5747916B2 (da) * 1974-05-13 1982-10-13
DE2503235A1 (de) * 1975-01-27 1976-07-29 Boehringer Sohn Ingelheim Neues verfahren zur herstellung von 8-brom-thieno-triazolo-1,4-diazepinen
DE2533924C3 (de) * 1975-07-30 1979-05-03 C.H. Boehringer Sohn, 6507 Ingelheim Verfahren zur Herstellung von 6- Aryl-4H-striazolo [3,4-c] thieno [2,3-e] 1,4-diazepinen
DE2531678C3 (de) * 1975-07-16 1979-06-28 C.H. Boehringer Sohn, 6507 Ingelheim Thieno [2,3e] triazole [3,4c] 5,6-dihydro-l,4diazepine und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
SE439920B (sv) 1985-07-08
NO782499L (no) 1979-01-23
CA1087182A (en) 1980-10-07
FR2398070A1 (fr) 1979-02-16
GB2001972B (en) 1982-01-06
DK325178A (da) 1979-01-22
IT1107490B (it) 1985-11-25
GB2001972A (en) 1979-02-14
ES471886A1 (es) 1979-02-01
ES472812A1 (es) 1979-02-16
IE47336B1 (en) 1984-02-22
LU80002A1 (de) 1979-09-06
DK150306C (da) 1987-11-09
JPS6254114B2 (da) 1987-11-13
AU515885B2 (en) 1981-05-07
CS209897B2 (en) 1981-12-31
NZ187915A (en) 1980-10-08
RO75609A (ro) 1981-01-30
SU725564A1 (ru) 1980-03-30
AU3820978A (en) 1980-01-24
HU176485B (en) 1981-03-28
SU725564A3 (en) 1980-03-30
SE7808019L (sv) 1979-01-22
FR2398070B1 (da) 1982-05-21
JPS5422395A (en) 1979-02-20
DD137934A5 (de) 1979-10-03
EP0000479B1 (de) 1981-01-07
SU793402A3 (ru) 1980-12-30
PT68330A (de) 1978-08-01
FI782025A (fi) 1979-01-22
FI63033B (fi) 1982-12-31
GR65022B (en) 1980-06-16
IE781456L (en) 1979-01-21
EP0000479A1 (de) 1979-02-07
IT7850381A0 (it) 1978-07-19
IL55169A0 (en) 1978-09-29
NL7807762A (nl) 1979-01-23
PH14236A (en) 1981-04-09
CH642374A5 (de) 1984-04-13
PL208542A1 (pl) 1979-06-04
NO149889B (no) 1984-04-02
PL115061B1 (en) 1981-03-31
IL55169A (en) 1982-04-30
NO149889C (no) 1984-07-11
US4180573A (en) 1979-12-25
AT363949B (de) 1981-09-10
DK150306B (da) 1987-02-02
ATA498978A (de) 1981-02-15
DE2860404D1 (en) 1981-02-26

Similar Documents

Publication Publication Date Title
US4062848A (en) Tetracyclic compounds
FI63582B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 11(1-piperazinyl)-pyrazino(2,3-b)(1,5)bensoxazepiner och -b enotiazepiner
FI68835C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-minoacyl-1,4,9,10-tetrahydropyrazolo(4,3-b)(1,5)bensodiaz epn-10-oner
FI63033C (fi) Foerfarande foer framstaellning av anxiolytiska tranquilliserande sedativa och/eller neuroleptiska substituerade 1-piperazinyl-4h-s-triazolo(3,4-c)tieno(2,3-e)-1,4-diazepiner
NZ233574A (en) Thieno-triazolo-diazepine derivatives
Press et al. Thiophene systems. 5. Thieno [3, 4-b][1, 5] benzoxazepines, thieno [3, 4-b][1, 5] benzothiazepines, and thieno [3, 4-b][1, 4] benzodiazepines as potential central nervous system agents
FI71150C (fi) Foerfarande foer framstaellning av som neuroleptiska laekemedel anvaendbara 2,4-dihydro-1,2,3-triazolo/4,5-b/ /1,5/bensodiazepinderivat
CS255897B2 (en) Process for preparing 1,2,4-triazolocarbamates
US4447361A (en) Aryl substituted pyrido[1,4]benzodiazepines
EP0057428B1 (de) Tricyclische Pyrrole, Verfahren zu ihrer Herstellung, ihre Anwendung sowie sie enthaltende Arzneimittel
DE2233682A1 (de) 2- eckige klammer auf 3-(subst. aminomethyl)-4-h-1,2,4-triazol-4-yl eckige klammer zu -benzophenone, ein verfahren zu ihrer herstellung sowie diese enthaltende arzneimittel
CA1128935A (en) Pyrimido(1,6-a)indole derivatives
PT97570A (pt) Processo para a preparacao de derivados de benzotienopiridina
Di Braccio et al. 1, 5-Benzodiazepines XIV. Synthesis of new substituted 9H-bis-[1, 2, 4] triazolo [4, 3-a: 3′, 4′-d][1, 5] benzodiazepines and relate compounds endowed with in vitro cytotoxic properties
US4028356A (en) Triazinobenzodiazepines
US4016165A (en) Triazino benzodiazepines
WO1981000568A1 (en) Benzodiazepinones,a process for their preparation,their use and medicaments containing them
DD220307A5 (de) Verfahren zur herstellung von polycyclische carbonsaeureverbindungen
FI71935C (fi) FOERFARANDE FOER FRAMSTAELLNING AV 6-FENYL-11H-PYRIDO/2,3-B//1,4/BENSODIAZEPINER MED ANTIDEPRESSIV VERKAN. SIIRRETTY PAEIVAEMAEAERAE-FOERSKJUTET DATUM PL 14 ç 10.06.82.
FI60016B (fi) Foerfarande foer framstaellning av terapeutiskt vaerdefulla substituerade 6-fenyl-4h-s-triazolo-(3,4c)-tieno(2,3e)-1,4-diazepiner
DE2460776C2 (de) 1-substituierte 6-Aryl-4H-s-triazolo-(3,4c)-thieno-(2,3e)-1,4-diazepine, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate sowie Zwischenprodukte und Verfahren zur Herstellung dieser Zwischenprodukte
FI63589B (fi) Foerfarande foer framstaellning av terapeutiskt aktiva 6-(7-klor-1,8-naftyridin-2-yl)-5-karbamoyloxi-7-oxo-6,7-dihydro-5h-pyrrolo(3,4-b)pyraziner
CA1140934A (en) Aminobenzoic acid derivatives, their preparation and their use as pharmaceutical compositions or as intermediates
CS203085B2 (cs) Způsob výroby nových substituovaných B-aryl-4H-s- -triazolo[3,4-c ] thieno(2,3-e ] -1,4-diazepinů
EP0076017A2 (en) Phenyl substituted pyrido(1,4)benzodiazepines and intermediates therefor

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: C.H. BOEHRINGER SOHN