FI61703C - Foerfarande foer framstaellning av farmakologiskt vaerdefulla hydroxialkylxantiner - Google Patents

Foerfarande foer framstaellning av farmakologiskt vaerdefulla hydroxialkylxantiner Download PDF

Info

Publication number
FI61703C
FI61703C FI2065/74A FI206574A FI61703C FI 61703 C FI61703 C FI 61703C FI 2065/74 A FI2065/74 A FI 2065/74A FI 206574 A FI206574 A FI 206574A FI 61703 C FI61703 C FI 61703C
Authority
FI
Finland
Prior art keywords
compounds
carbon atoms
group
xanthine
methyl
Prior art date
Application number
FI2065/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI61703B (fi
FI206574A (fr
Inventor
Werner Mohler
Manfred Jayme
Heinz-Joachim Hinze
Jaromir Komarek
Mario Reiser
Alfons Soeder
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI206574A publication Critical patent/FI206574A/fi
Application granted granted Critical
Publication of FI61703B publication Critical patent/FI61703B/fi
Publication of FI61703C publication Critical patent/FI61703C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/10Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI2065/74A 1973-07-11 1974-07-05 Foerfarande foer framstaellning av farmakologiskt vaerdefulla hydroxialkylxantiner FI61703C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2335170A DE2335170C2 (de) 1973-07-11 1973-07-11 1,3-Dialkyl-7-(hydroxyalkyl)-xanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE2335170 1973-07-11

Publications (3)

Publication Number Publication Date
FI206574A FI206574A (fr) 1975-01-12
FI61703B FI61703B (fi) 1982-05-31
FI61703C true FI61703C (fi) 1982-09-10

Family

ID=5886518

Family Applications (1)

Application Number Title Priority Date Filing Date
FI2065/74A FI61703C (fi) 1973-07-11 1974-07-05 Foerfarande foer framstaellning av farmakologiskt vaerdefulla hydroxialkylxantiner

Country Status (17)

Country Link
US (1) US4108995A (fr)
AR (4) AR199915A1 (fr)
AT (1) AT333300B (fr)
BE (1) BE816869R (fr)
CA (1) CA1062709A (fr)
CH (4) CH587852A5 (fr)
DE (1) DE2335170C2 (fr)
DK (1) DK147004C (fr)
ES (3) ES417828A1 (fr)
FI (1) FI61703C (fr)
FR (1) FR2236501B2 (fr)
GB (1) GB1480836A (fr)
IE (1) IE41822B1 (fr)
NL (1) NL168703C (fr)
NO (2) NO140596C (fr)
SE (1) SE415354B (fr)
ZA (1) ZA744373B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207321A (en) * 1977-04-02 1980-06-10 Hoechst Aktiengesellschaft Pharmaceutical compositions containing xanthines
DE3138397A1 (de) * 1981-09-26 1983-04-07 Hoechst Ag, 6230 Frankfurt "arzneimittel, darin enthaltene vicinale dihydroxyalkylxanthine und herstellungsverfahren fuer diese xanthinverbindungen"
US4636507A (en) * 1984-04-30 1987-01-13 Hoechst-Roussel Pharmaceuticals Inc. Host defense mechanism enhancement
DE3525801A1 (de) * 1985-07-19 1987-01-22 Hoechst Ag Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
US5338741A (en) * 1986-10-27 1994-08-16 Nestec S.A. 1-hydroxyalkylxanthines and medicaments containing them
DE3725554A1 (de) * 1987-08-01 1989-02-09 Hoechst Ag Pharmazeutisches kombinationspraeparat sowie dessen herstellung und verwendung
DE3942871A1 (de) * 1989-12-23 1991-06-27 Hoechst Ag R-(-)-1-(5-hydroxyhexyl)-3-methyl-7-propylxanthin, verfahren zu dessen herstellung und diese verbindung enthaltende arzneimittel
EP0570831A2 (fr) * 1992-05-20 1993-11-24 Hoechst Aktiengesellschaft Utilisation de dérivés de Xanthine pour le traitement de dommages cérébraux après interruption de la circulation sanguine
US5856330A (en) * 1996-07-31 1999-01-05 Hoechst Aktiengesellschaft Use of xanthine derivatives for the inhibition of dephosphorylation of cofilin
US5981536A (en) * 1996-07-31 1999-11-09 Hoechst Aktiengesellschaft Use of xanthine derivatives for the modulation of apoptosis
WO1999031101A1 (fr) * 1997-12-17 1999-06-24 University Of South Florida Antagonistes du recepteur de l'adenosine presentant une bioactivite amelioree

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2756229A (en) * 1956-07-24 Xanthine derivatives
US2517410A (en) * 1947-08-15 1950-08-01 Searle & Co Hydroxy alkyl xanthines and the production thereof
DE926788C (de) * 1952-11-07 1955-04-25 Geigy Ag J R Verfahren zur Herstellung von 1, 3-dialkylierten 7-Oxyalkyl-xanthinabkoemmlingen
FR1211333A (fr) * 1955-10-19 1960-03-15 Boehringer Sohn Ingelheim Perfectionnements apportés aux procédés pour fabriquer des oxyalcoylxanthines
DE1810705C3 (de) * 1968-11-25 1980-11-27 Hoechst Ag, 6000 Frankfurt Stabilisierung von Vitaminen
DE1911279A1 (de) * 1969-03-05 1970-11-12 Eckert Dr Theodor Verfahren zur Erhoehung der Resorptionsfaehigkeit von Arzneistoffen

Also Published As

Publication number Publication date
CH587851A5 (fr) 1977-05-13
DE2335170A1 (de) 1975-01-30
SE415354B (sv) 1980-09-29
AU7101974A (en) 1976-01-15
NL168703C (nl) 1982-05-17
DE2335170C2 (de) 1989-07-20
ES437151A1 (es) 1977-01-16
NO790627L (no) 1975-01-14
FR2236501A2 (fr) 1975-02-07
AR202662A1 (es) 1975-06-30
GB1480836A (en) 1977-07-27
NL7311123A (nl) 1975-01-14
CA1062709A (fr) 1979-09-18
IE41822L (en) 1975-01-11
NL168703B (nl) 1981-12-16
AT333300B (de) 1976-11-10
NO742464L (fr) 1975-02-10
NO140596B (no) 1979-06-25
FR2236501B2 (fr) 1979-08-10
AR199915A1 (es) 1974-10-08
ES437150A1 (es) 1977-01-16
BE816869R (fr) 1974-12-27
AR202663A1 (es) 1975-06-30
ES417828A1 (es) 1976-03-16
DK438373A (fr) 1975-03-03
ZA744373B (en) 1975-07-30
NO143064B (no) 1980-09-01
CH587852A5 (fr) 1977-05-13
NO143064C (no) 1980-12-10
ATA684573A (de) 1976-03-15
NO140596C (no) 1979-10-03
DK147004C (da) 1984-08-20
AR200626A1 (es) 1974-11-22
IE41822B1 (en) 1980-04-09
CH587850A5 (fr) 1977-05-13
DK147004B (da) 1984-03-12
SE7310986L (sv) 1975-01-13
FI61703B (fi) 1982-05-31
US4108995A (en) 1978-08-22
FI206574A (fr) 1975-01-12
CH587853A5 (fr) 1977-05-13

Similar Documents

Publication Publication Date Title
US4289776A (en) Xanthine derivatives
FI89921B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara tertiaera hydroxialkylxantiner
FI61703C (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla hydroxialkylxantiner
EP0103497B1 (fr) Nouveaux dérivés de la xanthine, leur procédé de préparation et les compositions pharmaceutiques les renfermant
EP0051829A1 (fr) Acides oméga-(2-oxo-4-imidazolin-1-yl)alcanoiques N-substitués, leurs sels et esters, leur procédé de fabrication et compositions pharmaceutiques contenant ces substances actives
PL163884B1 (pl) Sposób wytwarzania fluoksetyny PL PL PL
JPS62116583A (ja) プリン誘導体
JPH0222075B2 (fr)
US3734911A (en) Dialkyl-xanthine derivatives
ITMI941494A1 (it) Derivati del fenilcarbammato atti all'impiego come anticolinesterasici
Montgomery et al. Synthesis of potential anticancer agents. XXX.(1-Aziridinyl) purines
US5314890A (en) 1-7 disubstituted xanthine derivatives having antiasthmatic activity, their physiologically acceptable salts, pharmaceutical compositions containing them and process for their preparation
CA1075237A (fr) Derives de la purine
US4512990A (en) Benzthiazine analogs as antiinflammatory agents
US3905990A (en) Basically substituted benzimidazole derivatives
RU2159617C2 (ru) Производные ксантина, их стереоизомеры и физиологически переносимые соли, фармацевтическая композиция, обладающая уменьшающей патологическую гиперактивность эозинофильных гранулятов активностью
US3926995A (en) Theophylline derivatives
JPS6141915B2 (fr)
CA1086316A (fr) Nucleosides acycliques de purine
HU187650B (en) Process for preparing of new 12-substituated carbamide derivatives of ergolins
KR930010559B1 (ko) 1-히드록시알킬크산틴류, 그의 제조방법
US3414572A (en) Basic substituted alkylxanthine derivatives
DE2366527C2 (fr)
GB1561380A (en) Esters of hydroxyalkoxyalkyl purines their preparation and pharmaceutical compositions containing them
CA1075692A (fr) Derives de la xanthine