FI59402C - Foerfarande foer framstaellning av ett terapeutiskt anvaendbart 1-ftalazonderivat - Google Patents

Foerfarande foer framstaellning av ett terapeutiskt anvaendbart 1-ftalazonderivat Download PDF

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Publication number
FI59402C
FI59402C FI3157/74A FI315774A FI59402C FI 59402 C FI59402 C FI 59402C FI 3157/74 A FI3157/74 A FI 3157/74A FI 315774 A FI315774 A FI 315774A FI 59402 C FI59402 C FI 59402C
Authority
FI
Finland
Prior art keywords
compound
formula
group
methyl
phthalazone
Prior art date
Application number
FI3157/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI315774A (xx
FI59402B (fi
Inventor
Michiro Inoue
Masayuki Ishikawa
Takashi Tsuchiya
Takio Shimamoto
Original Assignee
Michiro Inoue
Masayuki Ishikawa
Takashi Tsuchiya
Takio Shimamoto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP12126073A external-priority patent/JPS5732065B2/ja
Priority claimed from JP12175773A external-priority patent/JPS5724786B2/ja
Application filed by Michiro Inoue, Masayuki Ishikawa, Takashi Tsuchiya, Takio Shimamoto filed Critical Michiro Inoue
Publication of FI315774A publication Critical patent/FI315774A/fi
Application granted granted Critical
Publication of FI59402B publication Critical patent/FI59402B/fi
Publication of FI59402C publication Critical patent/FI59402C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/89Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI3157/74A 1973-10-30 1974-10-29 Foerfarande foer framstaellning av ett terapeutiskt anvaendbart 1-ftalazonderivat FI59402C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP12126073 1973-10-30
JP12126073A JPS5732065B2 (xx) 1973-10-30 1973-10-30
JP12175773A JPS5724786B2 (xx) 1973-10-31 1973-10-31
JP12175773 1973-10-31

Publications (3)

Publication Number Publication Date
FI315774A FI315774A (xx) 1975-05-01
FI59402B FI59402B (fi) 1981-04-30
FI59402C true FI59402C (fi) 1981-08-10

Family

ID=26458679

Family Applications (1)

Application Number Title Priority Date Filing Date
FI3157/74A FI59402C (fi) 1973-10-30 1974-10-29 Foerfarande foer framstaellning av ett terapeutiskt anvaendbart 1-ftalazonderivat

Country Status (20)

Country Link
US (1) US3963716A (xx)
AR (1) AR205004A1 (xx)
CA (1) CA1029377A (xx)
CH (2) CH610892A5 (xx)
DD (1) DD119231A5 (xx)
DE (1) DE2451417C3 (xx)
DK (1) DK134345B (xx)
ES (1) ES431454A1 (xx)
FI (1) FI59402C (xx)
FR (1) FR2248841B1 (xx)
GB (1) GB1459606A (xx)
HU (1) HU168797B (xx)
IE (1) IE39831B1 (xx)
IL (1) IL45675A (xx)
IN (1) IN139552B (xx)
LU (1) LU71191A1 (xx)
NL (1) NL7414186A (xx)
PH (1) PH10519A (xx)
SE (1) SE412389B (xx)
YU (1) YU289774A (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4120960A (en) * 1973-10-31 1978-10-17 The Boots Company Limited Therapeutic agents
NL7702763A (nl) * 1976-03-18 1977-09-20 Takio Shimamoto En Masayuki Is Werkwijze voor de bereiding van thromboxaan- -antagonisten en van preparaten die deze stof- fen bevatten.
IE47592B1 (en) * 1977-12-29 1984-05-02 Ici Ltd Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
US4293553A (en) * 1978-08-11 1981-10-06 Masayuki Ishikawa 1-Phthalazone derivatives, and use thereof
US4464532A (en) * 1979-07-31 1984-08-07 Nippon Kayaku Kabushiki Kaisha Intermediates of 7-alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone
JPS5668609A (en) * 1979-11-07 1981-06-09 Nippon Kayaku Co Ltd Phthalazinol preparation
JPS58116471A (ja) * 1981-12-29 1983-07-11 Nippon Kayaku Co Ltd 4−ヒドロキシメチル−1−フタラゾンエステル誘導体およびその塩
GB2127805A (en) * 1982-09-13 1984-04-18 Showa Denko Kk Phthalazones
US4861778A (en) * 1986-06-16 1989-08-29 Research Corporation 2,3-dihydrophthalazine-1,4-diones
CA1334969C (en) * 1988-08-19 1995-03-28 Mark James Suto Substituted dihydroisoquinoline and phthalazine derivatives as potentiators of the lethal effects of radiation and certain chemotherapeutic agents, selected compounds, analogs andprocess
US5177075A (en) * 1988-08-19 1993-01-05 Warner-Lambert Company Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process
DE4333761A1 (de) * 1993-10-04 1995-04-06 Luitpold Pharma Gmbh Heterocyclische Carbamate, Verfahren zu ihrer Herstellung und Arzneimittel
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA3089569C (en) 2007-06-04 2023-12-05 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
ES2525748T3 (es) 2009-11-13 2014-12-29 Toray Industries, Inc. Agente terapéutico o profiláctico para la diabetes
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN108676076A (zh) 2011-03-01 2018-10-19 辛纳吉制药公司 制备鸟苷酸环化酶c激动剂的方法
JP6499591B2 (ja) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
RS65632B1 (sr) 2013-06-05 2024-07-31 Bausch Health Ireland Ltd Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe
WO2015021358A2 (en) 2013-08-09 2015-02-12 Dominique Charmot Compounds and methods for inhibiting phosphate transport
JP2022533251A (ja) 2019-05-21 2022-07-21 アルデリックス, インコーポレイテッド 患者において血清リン酸塩を低下させるための組み合わせ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5116430B2 (xx) * 1971-08-05 1976-05-24
US3870792A (en) * 1972-07-24 1975-03-11 Michiro Inoue Certain dihydrophthalizines for treating hemorrhage and thrombosis

Also Published As

Publication number Publication date
CA1029377A (en) 1978-04-11
SE412389B (sv) 1980-03-03
IL45675A (en) 1978-10-31
FR2248841A1 (xx) 1975-05-23
FI315774A (xx) 1975-05-01
CH610892A5 (xx) 1979-05-15
IE39831L (en) 1975-04-30
YU289774A (en) 1983-01-21
DD119231A5 (xx) 1976-04-12
DK134345B (da) 1976-10-25
DK134345C (xx) 1977-03-21
LU71191A1 (xx) 1975-04-17
SE7413530L (xx) 1975-05-02
IN139552B (xx) 1976-07-03
HU168797B (xx) 1976-07-28
AR205004A1 (es) 1976-03-31
DK561874A (xx) 1975-07-07
DE2451417A1 (de) 1975-05-07
US3963716A (en) 1976-06-15
ES431454A1 (es) 1976-10-16
IL45675A0 (en) 1974-11-29
DE2451417C3 (de) 1981-01-29
NL7414186A (nl) 1975-05-02
IE39831B1 (en) 1979-01-03
AU7295474A (en) 1976-03-11
FR2248841B1 (xx) 1978-07-28
CH611282A5 (xx) 1979-05-31
GB1459606A (en) 1976-12-22
FI59402B (fi) 1981-04-30
PH10519A (en) 1977-05-26
DE2451417B2 (de) 1980-05-14

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