PH10519A - 4-hydroxymethyl-1-phthalazone derivatives and pharmaceutical compositions thereof - Google Patents
4-hydroxymethyl-1-phthalazone derivatives and pharmaceutical compositions thereofInfo
- Publication number
- PH10519A PH10519A PH16465A PH16465A PH10519A PH 10519 A PH10519 A PH 10519A PH 16465 A PH16465 A PH 16465A PH 16465 A PH16465 A PH 16465A PH 10519 A PH10519 A PH 10519A
- Authority
- PH
- Philippines
- Prior art keywords
- hydroxymethyl
- pharmaceutical compositions
- phthalazone derivatives
- phthalazone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/89—Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12126073A JPS5732065B2 (xx) | 1973-10-30 | 1973-10-30 | |
| JP12175773A JPS5724786B2 (xx) | 1973-10-31 | 1973-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH10519A true PH10519A (en) | 1977-05-26 |
Family
ID=26458679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH16465A PH10519A (en) | 1973-10-30 | 1974-10-30 | 4-hydroxymethyl-1-phthalazone derivatives and pharmaceutical compositions thereof |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US3963716A (xx) |
| AR (1) | AR205004A1 (xx) |
| CA (1) | CA1029377A (xx) |
| CH (2) | CH610892A5 (xx) |
| DD (1) | DD119231A5 (xx) |
| DE (1) | DE2451417C3 (xx) |
| DK (1) | DK134345B (xx) |
| ES (1) | ES431454A1 (xx) |
| FI (1) | FI59402C (xx) |
| FR (1) | FR2248841B1 (xx) |
| GB (1) | GB1459606A (xx) |
| HU (1) | HU168797B (xx) |
| IE (1) | IE39831B1 (xx) |
| IL (1) | IL45675A (xx) |
| IN (1) | IN139552B (xx) |
| LU (1) | LU71191A1 (xx) |
| NL (1) | NL7414186A (xx) |
| PH (1) | PH10519A (xx) |
| SE (1) | SE412389B (xx) |
| YU (1) | YU289774A (xx) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4120960A (en) * | 1973-10-31 | 1978-10-17 | The Boots Company Limited | Therapeutic agents |
| NL7702763A (nl) * | 1976-03-18 | 1977-09-20 | Takio Shimamoto En Masayuki Is | Werkwijze voor de bereiding van thromboxaan- -antagonisten en van preparaten die deze stof- fen bevatten. |
| IE47592B1 (en) * | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
| US4293553A (en) * | 1978-08-11 | 1981-10-06 | Masayuki Ishikawa | 1-Phthalazone derivatives, and use thereof |
| US4464532A (en) * | 1979-07-31 | 1984-08-07 | Nippon Kayaku Kabushiki Kaisha | Intermediates of 7-alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone |
| JPS5668609A (en) * | 1979-11-07 | 1981-06-09 | Nippon Kayaku Co Ltd | Phthalazinol preparation |
| JPS58116471A (ja) * | 1981-12-29 | 1983-07-11 | Nippon Kayaku Co Ltd | ４−ヒドロキシメチル−１−フタラゾンエステル誘導体およびその塩 |
| GB2127805A (en) * | 1982-09-13 | 1984-04-18 | Showa Denko Kk | Phthalazones |
| US4861778A (en) * | 1986-06-16 | 1989-08-29 | Research Corporation | 2,3-dihydrophthalazine-1,4-diones |
| CA1334969C (en) * | 1988-08-19 | 1995-03-28 | Mark James Suto | Substituted dihydroisoquinoline and phthalazine derivatives as potentiators of the lethal effects of radiation and certain chemotherapeutic agents, selected compounds, analogs andprocess |
| US5177075A (en) * | 1988-08-19 | 1993-01-05 | Warner-Lambert Company | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process |
| DE4333761A1 (de) * | 1993-10-04 | 1995-04-06 | Luitpold Pharma Gmbh | Heterocyclische Carbamate, Verfahren zu ihrer Herstellung und Arzneimittel |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US20100120694A1 (en) | 2008-06-04 | 2010-05-13 | Synergy Pharmaceuticals, Inc. | Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA3089569C (en) | 2007-06-04 | 2023-12-05 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| EP2321341B1 (en) | 2008-07-16 | 2017-02-22 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| ES2525748T3 (es) | 2009-11-13 | 2014-12-29 | Toray Industries, Inc. | Agente terapéutico o profiláctico para la diabetes |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| CN108676076A (zh) | 2011-03-01 | 2018-10-19 | 辛纳吉制药公司 | 制备鸟苷酸环化酶c激动剂的方法 |
| JP6499591B2 (ja) | 2013-02-25 | 2019-04-10 | シナジー ファーマシューティカルズ インコーポレイテッド | 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト |
| EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| JP2016514670A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト |
| RS65632B1 (sr) | 2013-06-05 | 2024-07-31 | Bausch Health Ireland Ltd | Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe |
| WO2015021358A2 (en) | 2013-08-09 | 2015-02-12 | Dominique Charmot | Compounds and methods for inhibiting phosphate transport |
| JP2022533251A (ja) | 2019-05-21 | 2022-07-21 | アルデリックス， インコーポレイテッド | 患者において血清リン酸塩を低下させるための組み合わせ |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5116430B2 (xx) * | 1971-08-05 | 1976-05-24 | ||
| US3870792A (en) * | 1972-07-24 | 1975-03-11 | Michiro Inoue | Certain dihydrophthalizines for treating hemorrhage and thrombosis |
-
1974
- 1974-01-01 AR AR256326A patent/AR205004A1/es active
- 1974-09-03 IE IE1825/74A patent/IE39831B1/en unknown
- 1974-09-04 GB GB3870874A patent/GB1459606A/en not_active Expired
- 1974-09-10 US US05/504,745 patent/US3963716A/en not_active Expired - Lifetime
- 1974-09-16 IL IL45675A patent/IL45675A/xx unknown
- 1974-10-23 FR FR7435550A patent/FR2248841B1/fr not_active Expired
- 1974-10-24 CA CA212,163A patent/CA1029377A/en not_active Expired
- 1974-10-28 DK DK561874AA patent/DK134345B/da not_active IP Right Cessation
- 1974-10-28 LU LU71191A patent/LU71191A1/xx unknown
- 1974-10-28 SE SE7413530A patent/SE412389B/xx not_active IP Right Cessation
- 1974-10-29 ES ES431454A patent/ES431454A1/es not_active Expired
- 1974-10-29 HU HUIO218A patent/HU168797B/hu unknown
- 1974-10-29 DE DE2451417A patent/DE2451417C3/de not_active Expired
- 1974-10-29 FI FI3157/74A patent/FI59402C/fi active
- 1974-10-29 YU YU02897/74A patent/YU289774A/xx unknown
- 1974-10-30 CH CH1454674A patent/CH610892A5/xx not_active IP Right Cessation
- 1974-10-30 CH CH497878A patent/CH611282A5/xx not_active IP Right Cessation
- 1974-10-30 DD DD182046A patent/DD119231A5/xx unknown
- 1974-10-30 NL NL7414186A patent/NL7414186A/xx not_active Application Discontinuation
- 1974-10-30 PH PH16465A patent/PH10519A/en unknown
-
1976
- 1976-02-25 IN IN330/CAL/76A patent/IN139552B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA1029377A (en) | 1978-04-11 |
| SE412389B (sv) | 1980-03-03 |
| IL45675A (en) | 1978-10-31 |
| FR2248841A1 (xx) | 1975-05-23 |
| FI315774A (xx) | 1975-05-01 |
| CH610892A5 (xx) | 1979-05-15 |
| IE39831L (en) | 1975-04-30 |
| YU289774A (en) | 1983-01-21 |
| DD119231A5 (xx) | 1976-04-12 |
| DK134345B (da) | 1976-10-25 |
| DK134345C (xx) | 1977-03-21 |
| LU71191A1 (xx) | 1975-04-17 |
| SE7413530L (xx) | 1975-05-02 |
| IN139552B (xx) | 1976-07-03 |
| HU168797B (xx) | 1976-07-28 |
| AR205004A1 (es) | 1976-03-31 |
| DK561874A (xx) | 1975-07-07 |
| DE2451417A1 (de) | 1975-05-07 |
| US3963716A (en) | 1976-06-15 |
| ES431454A1 (es) | 1976-10-16 |
| IL45675A0 (en) | 1974-11-29 |
| DE2451417C3 (de) | 1981-01-29 |
| NL7414186A (nl) | 1975-05-02 |
| IE39831B1 (en) | 1979-01-03 |
| AU7295474A (en) | 1976-03-11 |
| FR2248841B1 (xx) | 1978-07-28 |
| CH611282A5 (xx) | 1979-05-31 |
| GB1459606A (en) | 1976-12-22 |
| FI59402C (fi) | 1981-08-10 |
| FI59402B (fi) | 1981-04-30 |
| DE2451417B2 (de) | 1980-05-14 |
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