DK134345C - - Google Patents

Info

Publication number
DK134345C
DK134345C DK561874A DK561874A DK134345C DK 134345 C DK134345 C DK 134345C DK 561874 A DK561874 A DK 561874A DK 561874 A DK561874 A DK 561874A DK 134345 C DK134345 C DK 134345C
Authority
DK
Denmark
Application number
DK561874A
Other languages
Danish (da)
Other versions
DK134345B (da
DK561874A (xx
Inventor
M Inoue
M Ishikawa
T Tsuchiya
T Shimamoto
Original Assignee
M Inoue
M Ishikawa
T Tsuchiya
T Shimamoto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP12126073A external-priority patent/JPS5732065B2/ja
Priority claimed from JP12175773A external-priority patent/JPS5724786B2/ja
Application filed by M Inoue, M Ishikawa, T Tsuchiya, T Shimamoto filed Critical M Inoue
Publication of DK561874A publication Critical patent/DK561874A/da
Publication of DK134345B publication Critical patent/DK134345B/da
Application granted granted Critical
Publication of DK134345C publication Critical patent/DK134345C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/89Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK561874AA 1973-10-30 1974-10-28 Analogifremgangsmåde til fremstilling af 4-hydroxymethyl-1-phthalazonderivater. DK134345B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12126073A JPS5732065B2 (xx) 1973-10-30 1973-10-30
JP12175773A JPS5724786B2 (xx) 1973-10-31 1973-10-31

Publications (3)

Publication Number Publication Date
DK561874A DK561874A (xx) 1975-07-07
DK134345B DK134345B (da) 1976-10-25
DK134345C true DK134345C (xx) 1977-03-21

Family

ID=26458679

Family Applications (1)

Application Number Title Priority Date Filing Date
DK561874AA DK134345B (da) 1973-10-30 1974-10-28 Analogifremgangsmåde til fremstilling af 4-hydroxymethyl-1-phthalazonderivater.

Country Status (20)

Country Link
US (1) US3963716A (xx)
AR (1) AR205004A1 (xx)
CA (1) CA1029377A (xx)
CH (2) CH611282A5 (xx)
DD (1) DD119231A5 (xx)
DE (1) DE2451417C3 (xx)
DK (1) DK134345B (xx)
ES (1) ES431454A1 (xx)
FI (1) FI59402C (xx)
FR (1) FR2248841B1 (xx)
GB (1) GB1459606A (xx)
HU (1) HU168797B (xx)
IE (1) IE39831B1 (xx)
IL (1) IL45675A (xx)
IN (1) IN139552B (xx)
LU (1) LU71191A1 (xx)
NL (1) NL7414186A (xx)
PH (1) PH10519A (xx)
SE (1) SE412389B (xx)
YU (1) YU289774A (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4120960A (en) * 1973-10-31 1978-10-17 The Boots Company Limited Therapeutic agents
NL7702763A (nl) * 1976-03-18 1977-09-20 Takio Shimamoto En Masayuki Is Werkwijze voor de bereiding van thromboxaan- -antagonisten en van preparaten die deze stof- fen bevatten.
IE47592B1 (en) * 1977-12-29 1984-05-02 Ici Ltd Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
US4293553A (en) * 1978-08-11 1981-10-06 Masayuki Ishikawa 1-Phthalazone derivatives, and use thereof
US4464532A (en) * 1979-07-31 1984-08-07 Nippon Kayaku Kabushiki Kaisha Intermediates of 7-alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone
JPS5668609A (en) * 1979-11-07 1981-06-09 Nippon Kayaku Co Ltd Phthalazinol preparation
JPS58116471A (ja) * 1981-12-29 1983-07-11 Nippon Kayaku Co Ltd 4−ヒドロキシメチル−1−フタラゾンエステル誘導体およびその塩
GB2127805A (en) * 1982-09-13 1984-04-18 Showa Denko Kk Phthalazones
US4861778A (en) * 1986-06-16 1989-08-29 Research Corporation 2,3-dihydrophthalazine-1,4-diones
ES2067508T3 (es) * 1988-08-19 1995-04-01 Warner Lambert Co Dihidroisoquinolinonas sustituidas y compuestos relacionados como potenciadores de los efectos letales de la radiacion y de ciertos agentes quimioterapeuticos; compuestos seleccionados, analogos y proceso.
US5177075A (en) * 1988-08-19 1993-01-05 Warner-Lambert Company Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process
DE4333761A1 (de) * 1993-10-04 1995-04-06 Luitpold Pharma Gmbh Heterocyclische Carbamate, Verfahren zu ihrer Herstellung und Arzneimittel
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2328910B1 (en) 2008-06-04 2014-08-06 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
ES2525748T3 (es) 2009-11-13 2014-12-29 Toray Industries, Inc. Agente terapéutico o profiláctico para la diabetes
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA3100941C (en) 2011-03-01 2024-03-05 Synergy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
JP6499591B2 (ja) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
US10011637B2 (en) 2013-06-05 2018-07-03 Synergy Pharmaceuticals, Inc. Ultra-pure agonists of guanylate cyclase C, method of making and using same
KR102456567B1 (ko) 2013-08-09 2022-10-19 알데릭스, 인코포레이티드 인산염 수송을 억제하기 위한 화합물 및 방법
EP3972599A1 (en) 2019-05-21 2022-03-30 Ardelyx, Inc. Combination for lowering serum phosphate in a patient

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5116430B2 (xx) * 1971-08-05 1976-05-24
US3870792A (en) * 1972-07-24 1975-03-11 Michiro Inoue Certain dihydrophthalizines for treating hemorrhage and thrombosis

Also Published As

Publication number Publication date
CH611282A5 (xx) 1979-05-31
FR2248841A1 (xx) 1975-05-23
FI315774A (xx) 1975-05-01
PH10519A (en) 1977-05-26
HU168797B (xx) 1976-07-28
ES431454A1 (es) 1976-10-16
GB1459606A (en) 1976-12-22
FI59402B (fi) 1981-04-30
IL45675A0 (en) 1974-11-29
IL45675A (en) 1978-10-31
DE2451417B2 (de) 1980-05-14
YU289774A (en) 1983-01-21
DE2451417A1 (de) 1975-05-07
DK134345B (da) 1976-10-25
FR2248841B1 (xx) 1978-07-28
SE412389B (sv) 1980-03-03
DK561874A (xx) 1975-07-07
DD119231A5 (xx) 1976-04-12
DE2451417C3 (de) 1981-01-29
SE7413530L (xx) 1975-05-02
FI59402C (fi) 1981-08-10
IN139552B (xx) 1976-07-03
IE39831L (en) 1975-04-30
AR205004A1 (es) 1976-03-31
CH610892A5 (xx) 1979-05-15
NL7414186A (nl) 1975-05-02
IE39831B1 (en) 1979-01-03
AU7295474A (en) 1976-03-11
US3963716A (en) 1976-06-15
CA1029377A (en) 1978-04-11
LU71191A1 (xx) 1975-04-17

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Legal Events

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PBP Patent lapsed