FI59250C - Foerfarande foer framstaellning av cancerostatiskt och immunstimulerande verkande 4-imino-1,3-diazabicyklo-(3,1,0)-hexan-2-on - Google Patents

Foerfarande foer framstaellning av cancerostatiskt och immunstimulerande verkande 4-imino-1,3-diazabicyklo-(3,1,0)-hexan-2-on Download PDF

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Publication number
FI59250C
FI59250C FI761958A FI761958A FI59250C FI 59250 C FI59250 C FI 59250C FI 761958 A FI761958 A FI 761958A FI 761958 A FI761958 A FI 761958A FI 59250 C FI59250 C FI 59250C
Authority
FI
Finland
Prior art keywords
hexan
diazabicyclo
imino
immunications
immunication
Prior art date
Application number
FI761958A
Other languages
English (en)
Finnish (fi)
Other versions
FI59250B (fi
FI761958A (sv
Inventor
Uwe Bicker
Wolfgang Kampe
Wolfgang Steingross
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of FI761958A publication Critical patent/FI761958A/fi
Application granted granted Critical
Publication of FI59250B publication Critical patent/FI59250B/fi
Publication of FI59250C publication Critical patent/FI59250C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
FI761958A 1975-07-08 1976-07-05 Foerfarande foer framstaellning av cancerostatiskt och immunstimulerande verkande 4-imino-1,3-diazabicyklo-(3,1,0)-hexan-2-on FI59250C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19752530398 DE2530398A1 (de) 1975-07-08 1975-07-08 Organische verbindung
DE2530398 1975-07-08

Publications (3)

Publication Number Publication Date
FI761958A FI761958A (sv) 1977-01-09
FI59250B FI59250B (fi) 1981-03-31
FI59250C true FI59250C (fi) 1981-07-10

Family

ID=5950951

Family Applications (1)

Application Number Title Priority Date Filing Date
FI761958A FI59250C (fi) 1975-07-08 1976-07-05 Foerfarande foer framstaellning av cancerostatiskt och immunstimulerande verkande 4-imino-1,3-diazabicyklo-(3,1,0)-hexan-2-on

Country Status (26)

Country Link
US (1) US4083987A (sv)
JP (1) JPS5210290A (sv)
AR (1) AR208802A1 (sv)
AT (1) AT345846B (sv)
AU (1) AU497292B2 (sv)
BE (1) BE843803A (sv)
CA (1) CA1069125A (sv)
CH (1) CH598259A5 (sv)
CS (1) CS198195B2 (sv)
DD (1) DD125079A5 (sv)
DE (1) DE2530398A1 (sv)
DK (1) DK139752C (sv)
ES (1) ES449597A1 (sv)
FI (1) FI59250C (sv)
FR (1) FR2316945A1 (sv)
GB (1) GB1490486A (sv)
HU (1) HU170252B (sv)
IL (1) IL49964A (sv)
IN (1) IN146367B (sv)
LU (1) LU75314A1 (sv)
NL (1) NL160564C (sv)
PL (1) PL98937B1 (sv)
PT (1) PT65327B (sv)
SE (1) SE409864B (sv)
SU (1) SU604482A3 (sv)
ZA (1) ZA763977B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3825667A1 (de) * 1988-07-28 1990-03-15 Boehringer Mannheim Gmbh Verwendung von imexon als immunsuppressivum
US5369119A (en) * 1988-07-28 1994-11-29 Boehringer Mannheim Gmbh Use of imexon as an immune suppressive and pharmaceutical compositions containing imexon
DE3844655A1 (de) * 1988-07-28 1990-05-17 Boehringer Mannheim Gmbh Verwendung von imexon als immunsuppressivum
DE3841879A1 (de) * 1988-12-13 1990-06-21 Boehringer Mannheim Gmbh Neue imidazolidin-derivate, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
US20030129222A1 (en) * 2000-11-21 2003-07-10 Gabriel Lopez-Berestein Liposomal imexon
CA2431947A1 (en) * 2000-11-21 2002-05-30 Gabriel Lopez-Berestein Composition comprising an imexon or derivatives thereof and lipids
US6476236B1 (en) 2001-11-26 2002-11-05 The Arizona Board Of Regents Synthesis of 2-cyanoaziridine-1-carboxamide
WO2006042662A1 (de) * 2004-10-15 2006-04-27 Heidelberg Pharma Gmbh Parenterale darreichungsformen von imexon sowie verfahren zu deren herstellung
WO2008045686A2 (en) * 2006-10-12 2008-04-17 The Arizona Board Of Regents On Behalf Of The University Of Arizona Enantiomerically enriched iminopyrrolidone azirdine compositions

Also Published As

Publication number Publication date
SE7607675L (sv) 1977-01-09
ZA763977B (en) 1977-06-29
NL160564B (nl) 1979-06-15
JPS543876B2 (sv) 1979-02-27
ES449597A1 (es) 1977-08-01
JPS5210290A (en) 1977-01-26
SU604482A3 (ru) 1978-04-25
FR2316945B1 (sv) 1978-12-15
GB1490486A (en) 1977-11-02
IN146367B (sv) 1979-05-12
CA1069125A (en) 1980-01-01
NL160564C (nl) 1979-11-15
AU497292B2 (en) 1978-12-07
CS198195B2 (en) 1980-05-30
PL98937B1 (pl) 1978-05-31
IL49964A (en) 1978-07-31
DD125079A5 (sv) 1977-03-30
NL7607429A (nl) 1977-01-11
PT65327B (de) 1978-01-05
CH598259A5 (sv) 1978-04-28
LU75314A1 (sv) 1977-02-24
IL49964A0 (en) 1976-09-30
DK297176A (da) 1977-01-09
FR2316945A1 (fr) 1977-02-04
FI59250B (fi) 1981-03-31
HU170252B (sv) 1977-05-28
US4083987A (en) 1978-04-11
FI761958A (sv) 1977-01-09
PT65327A (de) 1976-08-01
DK139752B (da) 1979-04-09
DE2530398A1 (de) 1977-01-27
BE843803A (fr) 1977-01-05
SE409864B (sv) 1979-09-10
ATA493176A (de) 1978-02-15
AU1559676A (en) 1978-01-12
AT345846B (de) 1978-10-10
AR208802A1 (es) 1977-02-28
DK139752C (da) 1979-09-17

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MM Patent lapsed

Owner name: BOEHRINGER MANNHEIM GMBH