SU604482A3 - Способ получени 4-имино1,3-диазабицикло-(3,1,0)гексан-2она - Google Patents
Способ получени 4-имино1,3-диазабицикло-(3,1,0)гексан-2онаInfo
- Publication number
- SU604482A3 SU604482A3 SU762379563A SU2379563A SU604482A3 SU 604482 A3 SU604482 A3 SU 604482A3 SU 762379563 A SU762379563 A SU 762379563A SU 2379563 A SU2379563 A SU 2379563A SU 604482 A3 SU604482 A3 SU 604482A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- hexan
- preparing
- diazadicyclo
- amino
- imino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Description
(54) СПОСОБ ПОЛУЧШИЯ 4-ИМИНО-1,3-ДИАЗАБИЦИКЛО 3,1,0 ГЕКСАН-2-ОНА 34
Найдено, %: С 42,62; Н 4,03; N 37,52.тем, что 1-карбоксамидо-2-цианазиридин подвергаСцНдОМзют иэомеризавди в безводном пол рном раствориВычмслено , %: С 43,24; Н 4,53, N 37,82.теле, таком как спирт Ci-C4, с добавлением катаФормула изобретени Источники информации, прин тые во внимание
1. Способ получени 4-имино-1,3-диазабицикл }- Р экспертизе: 3,1,0 гексан-2-она, отличающийс 1. Патент ГДР N 110492, кл. С 07 D, 20.12.74.
604482 ,
литических коликств щелочи.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19752530398 DE2530398A1 (de) | 1975-07-08 | 1975-07-08 | Organische verbindung |
Publications (1)
Publication Number | Publication Date |
---|---|
SU604482A3 true SU604482A3 (ru) | 1978-04-25 |
Family
ID=5950951
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SU762379563A SU604482A3 (ru) | 1975-07-08 | 1976-07-08 | Способ получени 4-имино1,3-диазабицикло-(3,1,0)гексан-2она |
Country Status (26)
Country | Link |
---|---|
US (1) | US4083987A (ru) |
JP (1) | JPS5210290A (ru) |
AR (1) | AR208802A1 (ru) |
AT (1) | AT345846B (ru) |
AU (1) | AU497292B2 (ru) |
BE (1) | BE843803A (ru) |
CA (1) | CA1069125A (ru) |
CH (1) | CH598259A5 (ru) |
CS (1) | CS198195B2 (ru) |
DD (1) | DD125079A5 (ru) |
DE (1) | DE2530398A1 (ru) |
DK (1) | DK139752C (ru) |
ES (1) | ES449597A1 (ru) |
FI (1) | FI59250C (ru) |
FR (1) | FR2316945A1 (ru) |
GB (1) | GB1490486A (ru) |
HU (1) | HU170252B (ru) |
IL (1) | IL49964A (ru) |
IN (1) | IN146367B (ru) |
LU (1) | LU75314A1 (ru) |
NL (1) | NL160564C (ru) |
PL (1) | PL98937B1 (ru) |
PT (1) | PT65327B (ru) |
SE (1) | SE409864B (ru) |
SU (1) | SU604482A3 (ru) |
ZA (1) | ZA763977B (ru) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3825667A1 (de) * | 1988-07-28 | 1990-03-15 | Boehringer Mannheim Gmbh | Verwendung von imexon als immunsuppressivum |
US5369119A (en) * | 1988-07-28 | 1994-11-29 | Boehringer Mannheim Gmbh | Use of imexon as an immune suppressive and pharmaceutical compositions containing imexon |
DE3844655A1 (de) * | 1988-07-28 | 1990-05-17 | Boehringer Mannheim Gmbh | Verwendung von imexon als immunsuppressivum |
DE3841879A1 (de) * | 1988-12-13 | 1990-06-21 | Boehringer Mannheim Gmbh | Neue imidazolidin-derivate, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
US20030129222A1 (en) * | 2000-11-21 | 2003-07-10 | Gabriel Lopez-Berestein | Liposomal imexon |
CA2431947A1 (en) * | 2000-11-21 | 2002-05-30 | Gabriel Lopez-Berestein | Composition comprising an imexon or derivatives thereof and lipids |
US6476236B1 (en) | 2001-11-26 | 2002-11-05 | The Arizona Board Of Regents | Synthesis of 2-cyanoaziridine-1-carboxamide |
WO2006042662A1 (de) * | 2004-10-15 | 2006-04-27 | Heidelberg Pharma Gmbh | Parenterale darreichungsformen von imexon sowie verfahren zu deren herstellung |
WO2008045686A2 (en) * | 2006-10-12 | 2008-04-17 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Enantiomerically enriched iminopyrrolidone azirdine compositions |
-
1975
- 1975-07-08 DE DE19752530398 patent/DE2530398A1/de not_active Withdrawn
-
1976
- 1976-05-26 US US05/690,340 patent/US4083987A/en not_active Expired - Lifetime
- 1976-06-28 CA CA255,790A patent/CA1069125A/en not_active Expired
- 1976-06-29 DD DD193619A patent/DD125079A5/xx unknown
- 1976-07-01 DK DK297176A patent/DK139752C/da active
- 1976-07-02 AR AR263845A patent/AR208802A1/es active
- 1976-07-02 IL IL49964A patent/IL49964A/en unknown
- 1976-07-02 GB GB27657/76A patent/GB1490486A/en not_active Expired
- 1976-07-05 CH CH859076A patent/CH598259A5/xx not_active IP Right Cessation
- 1976-07-05 FI FI761958A patent/FI59250C/fi not_active IP Right Cessation
- 1976-07-05 HU HUBO1622A patent/HU170252B/hu unknown
- 1976-07-05 AU AU15596/76A patent/AU497292B2/en not_active Expired
- 1976-07-05 CS CS764432A patent/CS198195B2/cs unknown
- 1976-07-05 SE SE7607675A patent/SE409864B/xx unknown
- 1976-07-05 ZA ZA763977A patent/ZA763977B/xx unknown
- 1976-07-05 BE BE168650A patent/BE843803A/xx unknown
- 1976-07-06 ES ES449597A patent/ES449597A1/es not_active Expired
- 1976-07-06 LU LU75314A patent/LU75314A1/xx unknown
- 1976-07-06 AT AT493176A patent/AT345846B/de not_active IP Right Cessation
- 1976-07-06 NL NL7607429.A patent/NL160564C/xx not_active IP Right Cessation
- 1976-07-07 FR FR7620739A patent/FR2316945A1/fr active Granted
- 1976-07-07 PT PT65327A patent/PT65327B/pt unknown
- 1976-07-07 PL PL1976190969A patent/PL98937B1/pl unknown
- 1976-07-08 SU SU762379563A patent/SU604482A3/ru active
- 1976-07-08 JP JP51081456A patent/JPS5210290A/ja active Granted
-
1977
- 1977-07-01 IN IN992/CAL/77A patent/IN146367B/en unknown
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