FI57412C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 2-(tienyl-3'-amino)-1,3-diazasyklopenten-(2)-foereningar och deras syraadditionssalter - Google Patents
Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 2-(tienyl-3'-amino)-1,3-diazasyklopenten-(2)-foereningar och deras syraadditionssalter Download PDFInfo
- Publication number
- FI57412C FI57412C FI224770A FI224770A FI57412C FI 57412 C FI57412 C FI 57412C FI 224770 A FI224770 A FI 224770A FI 224770 A FI224770 A FI 224770A FI 57412 C FI57412 C FI 57412C
- Authority
- FI
- Finland
- Prior art keywords
- formula
- thienyl
- defined above
- amino
- group
- Prior art date
Links
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- BWKQVWQYYSAKHC-UHFFFAOYSA-N methylthiourea;hydroiodide Chemical compound I.CNC(N)=S BWKQVWQYYSAKHC-UHFFFAOYSA-N 0.000 description 1
- 150000002823 nitrates Chemical class 0.000 description 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 description 1
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl chloride Substances ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 description 1
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Substances [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 239000013558 reference substance Substances 0.000 description 1
- 210000002254 renal artery Anatomy 0.000 description 1
- 238000006798 ring closing metathesis reaction Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 238000001256 steam distillation Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 150000003512 tertiary amines Chemical class 0.000 description 1
- DKGYESBFCGKOJC-UHFFFAOYSA-N thiophen-3-amine Chemical class NC=1C=CSC=1 DKGYESBFCGKOJC-UHFFFAOYSA-N 0.000 description 1
- QUUCKKYYXIGURD-UHFFFAOYSA-N thiophen-3-ylthiourea Chemical compound NC(=S)NC=1C=CSC=1 QUUCKKYYXIGURD-UHFFFAOYSA-N 0.000 description 1
- LBLYYCQCTBFVLH-UHFFFAOYSA-M toluenesulfonate group Chemical class C=1(C(=CC=CC1)S(=O)(=O)[O-])C LBLYYCQCTBFVLH-UHFFFAOYSA-M 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- IMFACGCPASFAPR-UHFFFAOYSA-N tributylamine Chemical compound CCCCN(CCCC)CCCC IMFACGCPASFAPR-UHFFFAOYSA-N 0.000 description 1
- 238000001665 trituration Methods 0.000 description 1
- 230000036269 ulceration Effects 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- 150000003672 ureas Chemical class 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1941761 | 1969-08-16 | ||
| DE19691941761 DE1941761C3 (de) | 1969-08-16 | 2-(Thienyl-3 '-amino) -1.3-diazacyclopentene und Verfahren zu ihrer Herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI57412B FI57412B (fi) | 1980-04-30 |
| FI57412C true FI57412C (fi) | 1980-08-11 |
Family
ID=5742998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI224770A FI57412C (fi) | 1969-08-16 | 1970-08-14 | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 2-(tienyl-3'-amino)-1,3-diazasyklopenten-(2)-foereningar och deras syraadditionssalter |
Country Status (12)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10224892A1 (de) * | 2002-06-04 | 2003-12-18 | Aventis Pharma Gmbh | Substituierte Thiophene, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1969
- 1969-12-19 BR BR21536269A patent/BR6915362D0/pt unknown
-
1970
- 1970-07-31 IE IE99070A patent/IE34428B1/xx unknown
- 1970-08-11 IL IL35093A patent/IL35093A/xx unknown
- 1970-08-11 ZA ZA705543A patent/ZA705543B/xx unknown
- 1970-08-13 YU YU206970A patent/YU34295B/xx unknown
- 1970-08-14 NO NO311170A patent/NO129573B/no unknown
- 1970-08-14 SU SU1723841A patent/SU404244A3/ru active
- 1970-08-14 SU SU1723840A patent/SU423297A3/ru active
- 1970-08-14 DK DK419670A patent/DK144035C/da not_active IP Right Cessation
- 1970-08-14 FI FI224770A patent/FI57412C/fi active
- 1970-08-15 PL PL14272270A patent/PL81180B1/pl unknown
- 1970-08-17 JP JP7169970A patent/JPS5416500B1/ja active Pending
-
1972
- 1972-12-26 ES ES410034A patent/ES410034A1/es not_active Expired
- 1972-12-26 ES ES410035A patent/ES410035A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BR6915362D0 (pt) | 1973-01-04 |
| PL81180B1 (enrdf_load_stackoverflow) | 1975-08-30 |
| JPS5416500B1 (enrdf_load_stackoverflow) | 1979-06-22 |
| SU404244A3 (enrdf_load_stackoverflow) | 1973-10-26 |
| YU34295B (en) | 1979-04-30 |
| YU206970A (en) | 1978-10-31 |
| IE34428B1 (en) | 1975-05-14 |
| FI57412B (fi) | 1980-04-30 |
| NO129573B (enrdf_load_stackoverflow) | 1974-04-29 |
| DK144035C (da) | 1982-04-26 |
| SU399126A3 (enrdf_load_stackoverflow) | 1973-09-27 |
| ES410034A1 (es) | 1975-12-01 |
| ES410035A1 (es) | 1975-12-01 |
| IE34428L (en) | 1971-02-16 |
| DK144035B (da) | 1981-11-23 |
| ZA705543B (en) | 1971-04-28 |
| IL35093A0 (en) | 1970-10-30 |
| IL35093A (en) | 1974-01-14 |
| SU423297A3 (enrdf_load_stackoverflow) | 1974-04-05 |
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