FI55502B - Foerfarande foer framstaellning av trombos foerhindrande 4-amino-6-arylpyrimidiner - Google Patents
Foerfarande foer framstaellning av trombos foerhindrande 4-amino-6-arylpyrimidinerInfo
- Publication number
- FI55502B FI55502B FI2734/71A FI273471A FI55502B FI 55502 B FI55502 B FI 55502B FI 2734/71 A FI2734/71 A FI 2734/71A FI 273471 A FI273471 A FI 273471A FI 55502 B FI55502 B FI 55502B
- Authority
- FI
- Finland
- Prior art keywords
- arylpyrimidines
- amino
- procedure
- frame station
- station
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI773287A FI55834C (fi) | 1970-10-05 | 1977-11-02 | Foerfarande foer framstaellning av 4-hydroxi-5-etyl-6-fenylpyrimidin med bronchodilaterande verkan |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7821670A | 1970-10-05 | 1970-10-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI55502B true FI55502B (fi) | 1979-04-30 |
| FI55502C FI55502C (fi) | 1979-08-10 |
Family
ID=22142671
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI2734/71A FI55502C (fi) | 1970-10-05 | 1971-09-30 | Foerfarande foer framstaellning av trombos foerhindrande 4-amino-6-arylpyrimidiner |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US3707560A (fi) |
| JP (2) | JPS5648511B1 (fi) |
| AT (4) | AT314540B (fi) |
| AU (1) | AU465734B2 (fi) |
| BE (1) | BE773484A (fi) |
| CA (1) | CA988519A (fi) |
| CH (4) | CH554876A (fi) |
| DE (2) | DE2165962C2 (fi) |
| DK (1) | DK131858C (fi) |
| ES (4) | ES395676A1 (fi) |
| FI (1) | FI55502C (fi) |
| FR (1) | FR2110227B1 (fi) |
| GB (2) | GB1373536A (fi) |
| NL (1) | NL168511C (fi) |
| SE (2) | SE385885B (fi) |
| ZA (1) | ZA716615B (fi) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3895112A (en) * | 1970-10-05 | 1975-07-15 | Pfizer | Arylpyrimidines in the relaxation of smooth muscle |
| US3859288A (en) * | 1970-10-05 | 1975-01-07 | Pfizer | Arylpyrimidines - inhibitors of platelet aggregation and bronchodilators |
| US3908012A (en) * | 1970-10-05 | 1975-09-23 | Pfizer | Arylpyrimidines-inhibitors of platelet aggregation and bronchodilators |
| US3835132A (en) * | 1972-02-01 | 1974-09-10 | Shell Oil Co | Morpholino-piperazinyl pyrimidines |
| US3950525A (en) * | 1973-06-19 | 1976-04-13 | Pfizer Inc. | Relaxation of smooth muscle in a mammal |
| DE2343419A1 (de) * | 1973-08-29 | 1975-03-13 | Gruenenthal Chemie | Verfahren zur herstellung von pyrimidinderivaten |
| US4725600A (en) * | 1984-07-13 | 1988-02-16 | Fujisawa Pharmaceutical Co., Ltd. | Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent |
| JPH0625157B2 (ja) * | 1988-01-29 | 1994-04-06 | 宇部興産株式会社 | ４―ヒドロキシピリミジン類の製造方法 |
| US4935516A (en) * | 1988-01-29 | 1990-06-19 | Ube Industries, Ltd. | Process for preparing 4-hydroxypyrimidine |
| DE3825647A1 (de) * | 1988-07-28 | 1990-02-01 | Geyer Gmbh & Co Christian | Vorrichtung zur befestigung eines elektrischen schaltgeraetes |
| DE3905364A1 (de) * | 1989-02-22 | 1990-08-23 | Hoechst Ag | Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool |
| JP2003505384A (ja) | 1999-07-15 | 2003-02-12 | ファーマコピーア，インコーポレーティッド | ブラジキニンｂ１受容体アンタゴニスト |
| US7731985B2 (en) * | 2002-03-15 | 2010-06-08 | Ciba Specialty Chemicals Corporation | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces |
| AU2003247425B2 (en) * | 2002-05-22 | 2007-03-08 | Amgen Inc. | Amino-pyridine, -pyridine and pyridazine derivatives for use as vanilloid receptor ligands for the treatment of pain |
| CA2519265A1 (en) * | 2003-03-28 | 2004-10-07 | Pharmacia & Upjohn Company Llc | Positive allosteric modulators of the nicotinic acetylcholine receptor |
| WO2006113769A1 (en) * | 2005-04-15 | 2006-10-26 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| JP2009164373A (ja) * | 2008-01-08 | 2009-07-23 | Toshiba Corp | 半導体装置 |
| RU2012133475A (ru) * | 2010-01-25 | 2014-03-10 | Схди Фаундейшн, Инк. | Ингибиторы кинуренин-3-монооксигеназы, фармацевтические композиции и способы их применения |
| ES2629194T3 (es) | 2011-08-30 | 2017-08-07 | Chdi Foundation, Inc. | Inhibidores de kinurenina-3-monoxigenasa, composiciones farmacéuticas y métodos de utilización del mismo |
| MX2014002459A (es) | 2011-08-30 | 2014-04-10 | Chdi Foundation Inc | Inhibidores de quinurenina-3-monooxigenasa, composiciones farmaceuticas y metodos de uso de los mismos. |
| EP3169684B1 (en) | 2014-07-17 | 2019-06-26 | CHDI Foundation, Inc. | Combination of kmo inhibitor 6-(3-chloro-4-cyclopropoxyphenyl)pyrimidine-4-carboxylic acid with antiviral agent for treating hiv related neurological disorders |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3047462A (en) * | 1959-03-06 | 1962-07-31 | Lab Jacques Logeais Soc D Expl | Quinazolone anti-inflammatory composition |
-
1970
- 1970-10-05 US US78216A patent/US3707560A/en not_active Expired - Lifetime
-
1971
- 1971-09-30 FI FI2734/71A patent/FI55502C/fi active
- 1971-10-01 DK DK480171A patent/DK131858C/da not_active IP Right Cessation
- 1971-10-02 DE DE2165962A patent/DE2165962C2/de not_active Expired
- 1971-10-02 DE DE2149249A patent/DE2149249C3/de not_active Expired
- 1971-10-04 SE SE7112534-8A patent/SE385885B/xx unknown
- 1971-10-04 GB GB3831673A patent/GB1373536A/en not_active Expired
- 1971-10-04 ES ES395676A patent/ES395676A1/es not_active Expired
- 1971-10-04 SE SE7410488A patent/SE390304B/xx unknown
- 1971-10-04 CA CA124,312A patent/CA988519A/en not_active Expired
- 1971-10-04 ZA ZA716615A patent/ZA716615B/xx unknown
- 1971-10-04 GB GB4615871A patent/GB1373535A/en not_active Expired
- 1971-10-05 JP JP7823771A patent/JPS5648511B1/ja active Pending
- 1971-10-05 CH CH1452971A patent/CH554876A/fr not_active IP Right Cessation
- 1971-10-05 NL NLAANVRAGE7113670,A patent/NL168511C/xx not_active IP Right Cessation
- 1971-10-05 CH CH1521472A patent/CH554875A/fr not_active IP Right Cessation
- 1971-10-05 FR FR7135815A patent/FR2110227B1/fr not_active Expired
- 1971-10-05 CH CH772973A patent/CH542218A/fr not_active IP Right Cessation
- 1971-10-05 AT AT858071A patent/AT314540B/de not_active IP Right Cessation
- 1971-10-05 AT AT605473A patent/AT317229B/de not_active IP Right Cessation
- 1971-10-05 AT AT00149/73A patent/AT316563B/de not_active IP Right Cessation
- 1971-10-05 AT AT00148/73A patent/AT315856B/de not_active IP Right Cessation
- 1971-10-05 BE BE773484A patent/BE773484A/xx not_active IP Right Cessation
- 1971-10-05 CH CH1532172A patent/CH554346A/fr not_active IP Right Cessation
- 1971-10-06 AU AU34259/71A patent/AU465734B2/en not_active Expired
-
1973
- 1973-11-02 ES ES420211A patent/ES420211A1/es not_active Expired
- 1973-11-02 ES ES420210A patent/ES420210A1/es not_active Expired
- 1973-11-02 ES ES420209A patent/ES420209A1/es not_active Expired
-
1980
- 1980-08-11 JP JP11016380A patent/JPS5636468A/ja active Granted
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