SE390304B - Analogiforfarande for framstellning av 4-hydroxi-5-etyl-6-fonylpyrimidin - Google Patents
Analogiforfarande for framstellning av 4-hydroxi-5-etyl-6-fonylpyrimidinInfo
- Publication number
- SE390304B SE390304B SE7410488A SE7410488A SE390304B SE 390304 B SE390304 B SE 390304B SE 7410488 A SE7410488 A SE 7410488A SE 7410488 A SE7410488 A SE 7410488A SE 390304 B SE390304 B SE 390304B
- Authority
- SE
- Sweden
- Prior art keywords
- phonylpyrimidine
- hydroxy
- ethyl
- preparation
- analogical procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7821670A | 1970-10-05 | 1970-10-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7410488L SE7410488L (xx) | 1974-08-16 |
| SE390304B true SE390304B (sv) | 1976-12-13 |
Family
ID=22142671
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7112534-8A SE385885B (sv) | 1970-10-05 | 1971-10-04 | Foerfarande foer framstaellning av 4-amino-6-arylpyrimidinderivat |
| SE7410488A SE390304B (sv) | 1970-10-05 | 1971-10-04 | Analogiforfarande for framstellning av 4-hydroxi-5-etyl-6-fonylpyrimidin |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7112534-8A SE385885B (sv) | 1970-10-05 | 1971-10-04 | Foerfarande foer framstaellning av 4-amino-6-arylpyrimidinderivat |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US3707560A (xx) |
| JP (2) | JPS5648511B1 (xx) |
| AT (4) | AT315856B (xx) |
| AU (1) | AU465734B2 (xx) |
| BE (1) | BE773484A (xx) |
| CA (1) | CA988519A (xx) |
| CH (4) | CH554346A (xx) |
| DE (2) | DE2165962C2 (xx) |
| DK (1) | DK131858C (xx) |
| ES (4) | ES395676A1 (xx) |
| FI (1) | FI55502C (xx) |
| FR (1) | FR2110227B1 (xx) |
| GB (2) | GB1373536A (xx) |
| NL (1) | NL168511C (xx) |
| SE (2) | SE385885B (xx) |
| ZA (1) | ZA716615B (xx) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3859288A (en) * | 1970-10-05 | 1975-01-07 | Pfizer | Arylpyrimidines - inhibitors of platelet aggregation and bronchodilators |
| US3895112A (en) * | 1970-10-05 | 1975-07-15 | Pfizer | Arylpyrimidines in the relaxation of smooth muscle |
| US3908012A (en) * | 1970-10-05 | 1975-09-23 | Pfizer | Arylpyrimidines-inhibitors of platelet aggregation and bronchodilators |
| US3835132A (en) * | 1972-02-01 | 1974-09-10 | Shell Oil Co | Morpholino-piperazinyl pyrimidines |
| US3950525A (en) * | 1973-06-19 | 1976-04-13 | Pfizer Inc. | Relaxation of smooth muscle in a mammal |
| DE2343419A1 (de) * | 1973-08-29 | 1975-03-13 | Gruenenthal Chemie | Verfahren zur herstellung von pyrimidinderivaten |
| US4725600A (en) * | 1984-07-13 | 1988-02-16 | Fujisawa Pharmaceutical Co., Ltd. | Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent |
| JPH0625157B2 (ja) * | 1988-01-29 | 1994-04-06 | 宇部興産株式会社 | ４―ヒドロキシピリミジン類の製造方法 |
| US4935516A (en) * | 1988-01-29 | 1990-06-19 | Ube Industries, Ltd. | Process for preparing 4-hydroxypyrimidine |
| DE3825647A1 (de) * | 1988-07-28 | 1990-02-01 | Geyer Gmbh & Co Christian | Vorrichtung zur befestigung eines elektrischen schaltgeraetes |
| DE3905364A1 (de) * | 1989-02-22 | 1990-08-23 | Hoechst Ag | Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool |
| DE60005355T2 (de) * | 1999-07-15 | 2004-07-01 | Pharmacopeia, Inc. | Bradikinin b1 rezeptor antagonisten |
| WO2003077656A1 (en) * | 2002-03-15 | 2003-09-25 | Ciba Specialty Chemicals Holding Inc. | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces |
| CA2486376A1 (en) * | 2002-05-22 | 2003-12-04 | Amgen Inc. | Amino-pyridine, -pyridine and pyridazine derivatives for use as vanilloid receptor ligands for the treatment of pain |
| JP2006521345A (ja) * | 2003-03-28 | 2006-09-21 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | ニコチン性アセチルコリン受容体の正のアロステリック調節剤 |
| US20060235036A1 (en) * | 2005-04-15 | 2006-10-19 | Doherty Elizabeth M | Vanilloid receptor ligands and their use in treatments |
| JP2009164373A (ja) * | 2008-01-08 | 2009-07-23 | Toshiba Corp | 半導体装置 |
| EP2528441A4 (en) * | 2010-01-25 | 2013-07-10 | Chdi Foundation Inc | CERTAIN KYNURENIN-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF |
| SG2014011654A (en) | 2011-08-30 | 2014-08-28 | Chdi Foundation Inc | Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
| AU2012302144B2 (en) | 2011-08-30 | 2017-06-15 | Chdi Foundation, Inc. | Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
| CA2955379C (en) | 2014-07-17 | 2022-12-13 | Chdi Foundation, Inc. | Methods and compositions for treating hiv-related disorders |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3047462A (en) * | 1959-03-06 | 1962-07-31 | Lab Jacques Logeais Soc D Expl | Quinazolone anti-inflammatory composition |
-
1970
- 1970-10-05 US US78216A patent/US3707560A/en not_active Expired - Lifetime
-
1971
- 1971-09-30 FI FI2734/71A patent/FI55502C/fi active
- 1971-10-01 DK DK480171A patent/DK131858C/da not_active IP Right Cessation
- 1971-10-02 DE DE2165962A patent/DE2165962C2/de not_active Expired
- 1971-10-02 DE DE2149249A patent/DE2149249C3/de not_active Expired
- 1971-10-04 ZA ZA716615A patent/ZA716615B/xx unknown
- 1971-10-04 SE SE7112534-8A patent/SE385885B/xx unknown
- 1971-10-04 GB GB3831673A patent/GB1373536A/en not_active Expired
- 1971-10-04 SE SE7410488A patent/SE390304B/xx unknown
- 1971-10-04 GB GB4615871A patent/GB1373535A/en not_active Expired
- 1971-10-04 CA CA124,312A patent/CA988519A/en not_active Expired
- 1971-10-04 ES ES395676A patent/ES395676A1/es not_active Expired
- 1971-10-05 CH CH1532172A patent/CH554346A/fr not_active IP Right Cessation
- 1971-10-05 CH CH1452971A patent/CH554876A/fr not_active IP Right Cessation
- 1971-10-05 BE BE773484A patent/BE773484A/xx not_active IP Right Cessation
- 1971-10-05 JP JP7823771A patent/JPS5648511B1/ja active Pending
- 1971-10-05 FR FR7135815A patent/FR2110227B1/fr not_active Expired
- 1971-10-05 AT AT00148/73A patent/AT315856B/de not_active IP Right Cessation
- 1971-10-05 CH CH772973A patent/CH542218A/fr not_active IP Right Cessation
- 1971-10-05 AT AT858071A patent/AT314540B/de not_active IP Right Cessation
- 1971-10-05 AT AT00149/73A patent/AT316563B/de not_active IP Right Cessation
- 1971-10-05 NL NLAANVRAGE7113670,A patent/NL168511C/xx not_active IP Right Cessation
- 1971-10-05 CH CH1521472A patent/CH554875A/fr not_active IP Right Cessation
- 1971-10-05 AT AT605473A patent/AT317229B/de not_active IP Right Cessation
- 1971-10-06 AU AU34259/71A patent/AU465734B2/en not_active Expired
-
1973
- 1973-11-02 ES ES420210A patent/ES420210A1/es not_active Expired
- 1973-11-02 ES ES420209A patent/ES420209A1/es not_active Expired
- 1973-11-02 ES ES420211A patent/ES420211A1/es not_active Expired
-
1980
- 1980-08-11 JP JP11016380A patent/JPS5636468A/ja active Granted
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