FI3982960T3 - Perinnöllisen angioödeeman hoitoja - Google Patents
Perinnöllisen angioödeeman hoitoja Download PDFInfo
- Publication number
- FI3982960T3 FI3982960T3 FIEP20734283.3T FI20734283T FI3982960T3 FI 3982960 T3 FI3982960 T3 FI 3982960T3 FI 20734283 T FI20734283 T FI 20734283T FI 3982960 T3 FI3982960 T3 FI 3982960T3
- Authority
- FI
- Finland
- Prior art keywords
- compound
- formula
- solvate
- pharmaceutically acceptable
- acceptable salt
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962861725P | 2019-06-14 | 2019-06-14 | |
| GBGB1910116.1A GB201910116D0 (en) | 2019-07-15 | 2019-07-15 | Treatments of hereditary angioedema |
| PCT/GB2020/051439 WO2020249977A1 (en) | 2019-06-14 | 2020-06-15 | Treatments of hereditary angioedema |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI3982960T3 true FI3982960T3 (fi) | 2023-08-29 |
Family
ID=67700145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP20734283.3T FI3982960T3 (fi) | 2019-06-14 | 2020-06-15 | Perinnöllisen angioödeeman hoitoja |
Country Status (34)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201609607D0 (en) | 2016-06-01 | 2016-07-13 | Kalvista Pharmaceuticals Ltd | Polymorphs of N-(3-Fluoro-4-methoxypyridin-2-yl)methyl)-3-(methoxymethyl)-1-({4-((2-oxopy ridin-1-yl)methyl)phenyl}methyl)pyrazole-4-carboxamide and salts |
| GB201719881D0 (en) | 2017-11-29 | 2018-01-10 | Kalvista Pharmaceuticals Ltd | Solid forms of plasma kallikrein inhibitor and salts thereof |
| GB201910116D0 (en) * | 2019-07-15 | 2019-08-28 | Kalvista Pharmaceuticals Ltd | Treatments of hereditary angioedema |
| CN114206852A (zh) | 2019-08-09 | 2022-03-18 | 卡尔维斯塔制药有限公司 | 血浆激肽释放酶抑制剂 |
| WO2022084693A1 (en) * | 2020-10-23 | 2022-04-28 | Kalvista Pharmaceuticals Limited | Treatments of angioedema |
| EP4291186A1 (en) | 2021-02-09 | 2023-12-20 | Kalvista Pharmaceuticals Limited | Treatments of hereditary angioedema |
| ES2991820T3 (es) | 2022-04-27 | 2024-12-05 | Kalvista Pharmaceuticals Ltd | Formulaciones de un inhibidor de la calicreína plasmática |
| CN116003386B (zh) * | 2022-11-20 | 2024-03-26 | 药康众拓(北京)医药科技有限公司 | 一种氘代n-苄基吡啶酮吡唑甲酰胺类化合物、药物组合物和用途 |
| WO2025172693A1 (en) | 2024-02-13 | 2025-08-21 | Kalvista Pharmaceuticals Limited | Oral sebetralstat for the treatment of an attack of hereditary angioedema |
| WO2025172692A1 (en) | 2024-02-13 | 2025-08-21 | Kalvista Pharmaceuticals Limited | Oral sebetralstat for the treatment of an attack of hereditary angioedema |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5187157A (en) | 1987-06-05 | 1993-02-16 | Du Pont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
| GB9019558D0 (en) | 1990-09-07 | 1990-10-24 | Szelke Michael | Enzyme inhibitors |
| SE9301911D0 (sv) | 1993-06-03 | 1993-06-03 | Ab Astra | New peptide derivatives |
| US5589467A (en) | 1993-09-17 | 1996-12-31 | Novo Nordisk A/S | 2,5',N6-trisubstituted adenosine derivatives |
| GB0205527D0 (en) | 2002-03-08 | 2002-04-24 | Ferring Bv | Inhibitors |
| US7429604B2 (en) | 2004-06-15 | 2008-09-30 | Bristol Myers Squibb Company | Six-membered heterocycles useful as serine protease inhibitors |
| EP2051707B1 (en) | 2006-07-31 | 2013-07-17 | Activesite Pharmaceuticals, Inc. | Inhibitors of plasma kallikrein |
| DE102006050672A1 (de) | 2006-10-24 | 2008-04-30 | Curacyte Discovery Gmbh | Hemmstoffe des Plasmins und des Plasmakallikreins |
| JP2013121919A (ja) | 2010-03-25 | 2013-06-20 | Astellas Pharma Inc | 血漿カリクレイン阻害剤 |
| WO2012004678A2 (en) | 2010-07-07 | 2012-01-12 | The Medicines Company (Leipzig) Gmbh | Serine protease inhibitors |
| WO2012009009A2 (en) | 2010-07-14 | 2012-01-19 | Addex Pharma S.A. | Novel 2-amino-4-pyrazolyl-thiazole derivatives and their use as allosteric modulators of metabotropic glutamate receptors |
| US9290485B2 (en) | 2010-08-04 | 2016-03-22 | Novartis Ag | N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides |
| GB2494851A (en) | 2011-07-07 | 2013-03-27 | Kalvista Pharmaceuticals Ltd | Plasma kallikrein inhibitors |
| GB201300304D0 (en) | 2013-01-08 | 2013-02-20 | Kalvista Pharmaceuticals Ltd | Benzylamine derivatives |
| CN105452240B (zh) | 2013-05-23 | 2018-06-26 | 卡尔维斯塔制药有限公司 | 杂环衍生物 |
| EP2815749A1 (en) * | 2013-06-20 | 2014-12-24 | IP Gesellschaft für Management mbH | Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern |
| EP2886107A1 (en) * | 2013-12-17 | 2015-06-24 | ObsEva S.A. | Oral formulations of pyrrolydine derivatives |
| GB201421083D0 (en) | 2014-11-27 | 2015-01-14 | Kalvista Pharmaceuticals Ltd | Enzyme inhibitors |
| GB201721515D0 (en) * | 2017-12-21 | 2018-02-07 | Kalvista Pharmaceuticals Ltd | Dosage forms comprising a plasma kallikrein inhibtor |
| GB201910116D0 (en) | 2019-07-15 | 2019-08-28 | Kalvista Pharmaceuticals Ltd | Treatments of hereditary angioedema |
-
2019
- 2019-07-15 GB GBGB1910116.1A patent/GB201910116D0/en not_active Ceased
-
2020
- 2020-06-15 DK DK20734283.3T patent/DK3982960T3/da active
- 2020-06-15 AU AU2020293614A patent/AU2020293614B2/en active Active
- 2020-06-15 ES ES20734283T patent/ES2956471T3/es active Active
- 2020-06-15 HR HRP20230696TT patent/HRP20230696T1/hr unknown
- 2020-06-15 BR BR112021024664A patent/BR112021024664A2/pt not_active Application Discontinuation
- 2020-06-15 RS RS20230620A patent/RS64412B1/sr unknown
- 2020-06-15 CN CN202080043365.6A patent/CN114126612A/zh active Pending
- 2020-06-15 SG SG11202113304YA patent/SG11202113304YA/en unknown
- 2020-06-15 KR KR1020217043374A patent/KR102748728B1/ko active Active
- 2020-06-15 UA UAA202106869A patent/UA129869C2/uk unknown
- 2020-06-15 TW TW109120108A patent/TW202112370A/zh unknown
- 2020-06-15 JP JP2021571931A patent/JP7356518B2/ja active Active
- 2020-06-15 HU HUE20734283A patent/HUE063163T2/hu unknown
- 2020-06-15 MA MA56187A patent/MA56187B1/fr unknown
- 2020-06-15 CA CA3142218A patent/CA3142218A1/en active Pending
- 2020-06-15 FI FIEP20734283.3T patent/FI3982960T3/fi active
- 2020-06-15 EP EP23181261.1A patent/EP4282474A3/en active Pending
- 2020-06-15 MD MDE20220440T patent/MD3982960T2/ro unknown
- 2020-06-15 PL PL20734283.3T patent/PL3982960T3/pl unknown
- 2020-06-15 EA EA202193019A patent/EA202193019A1/ru unknown
- 2020-06-15 SI SI202030247T patent/SI3982960T1/sl unknown
- 2020-06-15 MY MYPI2021007320A patent/MY205687A/en unknown
- 2020-06-15 SM SM20230261T patent/SMT202300261T1/it unknown
- 2020-06-15 US US17/617,439 patent/US20220218680A1/en active Pending
- 2020-06-15 EP EP20734283.3A patent/EP3982960B1/en active Active
- 2020-06-15 PT PT207342833T patent/PT3982960T/pt unknown
- 2020-06-15 LT LTEPPCT/GB2020/051439T patent/LT3982960T/lt unknown
- 2020-06-15 MX MX2021014557A patent/MX2021014557A/es unknown
- 2020-06-15 WO PCT/GB2020/051439 patent/WO2020249977A1/en not_active Ceased
- 2020-06-15 PH PH1/2021/552966A patent/PH12021552966A1/en unknown
- 2020-06-16 AR ARP200101681A patent/AR119158A1/es unknown
-
2021
- 2021-12-02 IL IL288615A patent/IL288615A/en unknown
- 2021-12-06 CL CL2021003244A patent/CL2021003244A1/es unknown
- 2021-12-20 ZA ZA2021/10685A patent/ZA202110685B/en unknown
-
2023
- 2023-03-06 CL CL2023000639A patent/CL2023000639A1/es unknown
- 2023-08-14 JP JP2023131860A patent/JP7688078B2/ja active Active
-
2025
- 2025-05-21 JP JP2025084646A patent/JP2025124716A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI3982960T3 (fi) | Perinnöllisen angioödeeman hoitoja | |
| RU2004129324A (ru) | Применения бисфосфоновых кислот для лечения и профилактики остеопороза | |
| JP2011168580A (ja) | 医薬組成物 | |
| JPH0920659A (ja) | 炎症性腹部疾患のためのカッパ−アヘン製剤作働薬 | |
| JP2016507500A5 (enExample) | ||
| CN102036669A (zh) | 用于治疗早泄的药物组合物 | |
| JPWO2020249977A5 (enExample) | ||
| US3557292A (en) | Compositions and methods for treating parkinson's disease with combinations of l-3,4-dihydroxyphenylalanine and a hydrazine | |
| JP2011079854A (ja) | 洞房結節Ｉｆ電流阻害剤およびアンギオテンシン変換酵素阻害剤の新規な組み合わせならびにそれを含む医薬組成物 | |
| US20180125792A1 (en) | Non-steroidal anti-inflammatory drugs for cough | |
| US20080194877A1 (en) | Benzamidine Derivatives for Treatment and Prevention of Cancer Therapy Induced Mucositis | |
| Shao et al. | Treatment of infantile hemangioma by intralesional injection of propranolol combined with compound betamethasone | |
| JPWO2020249979A5 (enExample) | ||
| US20150079183A1 (en) | Lercanidipine Hydrochloride and Losartan Potassium Compound Preparation and Preparation Method Thereof | |
| KR100692235B1 (ko) | 안지오텐신 ⅱ 길항물질의 신규한 용도 | |
| US20190224208A1 (en) | Pharmaceutical composition for treating premature ejaculation and method for treating premature ejaculation | |
| NZ782935B2 (en) | Treatments of hereditary angioedema | |
| RU2412701C2 (ru) | Способ снижения непереносимости противотуберкулезных препаратов | |
| US5876751A (en) | Antispasmodic and antinflammatory composition and a process for the manufacture thereof | |
| CA2612179A1 (en) | A pharmaceutical composition comprising loratadine and its use to treat patients with upper respiratory mucosal congestion | |
| CN100409850C (zh) | 2h-[1,3]-噁嗪并[3,2-a]吲哚衍生物在制备治疗神经性疼痛的药物中的用途 | |
| NO333599B1 (no) | Anvendelse av distrontiumsalter av 2-[N,N-di(karboksymetyl)amino]-3-cyano-4-karboksymetyl-tiofen-5-karboksylsyre for fremstillingen av medikamenter for behandlingen av gastro-duodenal smerte | |
| CN1076195C (zh) | 含有锌化合物和对乙酰氨基苯乙酸的组合物 | |
| EP1611901B1 (en) | Preventive or remedy for teeth grinding | |
| EP0868915A1 (en) | An anti-spasmodic and antiinflammatory composition containing a NSAID, pentifenone and fenpiverinium |