FI3810633T3 - Yhdisteitä - Google Patents
Yhdisteitä Download PDFInfo
- Publication number
- FI3810633T3 FI3810633T3 FIEP19734346.0T FI19734346T FI3810633T3 FI 3810633 T3 FI3810633 T3 FI 3810633T3 FI 19734346 T FI19734346 T FI 19734346T FI 3810633 T3 FI3810633 T3 FI 3810633T3
- Authority
- FI
- Finland
- Prior art keywords
- compound
- spp
- pharmaceutical composition
- solvates
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
- C07K7/62—Polymyxins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862689602P | 2018-06-25 | 2018-06-25 | |
| PCT/EP2019/066819 WO2020002325A1 (en) | 2018-06-25 | 2019-06-25 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI3810633T3 true FI3810633T3 (fi) | 2024-02-09 |
Family
ID=67107423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP19734346.0T FI3810633T3 (fi) | 2018-06-25 | 2019-06-25 | Yhdisteitä |
Country Status (31)
| Country | Link |
|---|---|
| US (3) | US11459357B2 (https=) |
| EP (2) | EP3810633B1 (https=) |
| JP (2) | JP7488774B2 (https=) |
| KR (1) | KR20210054500A (https=) |
| CN (2) | CN112789287B (https=) |
| AR (1) | AR116663A1 (https=) |
| AU (2) | AU2019294261B2 (https=) |
| BR (1) | BR112020026663A2 (https=) |
| CA (1) | CA3103158A1 (https=) |
| CO (1) | CO2020016080A2 (https=) |
| DK (1) | DK3810633T3 (https=) |
| EA (1) | EA202092819A1 (https=) |
| ES (1) | ES2971732T3 (https=) |
| FI (1) | FI3810633T3 (https=) |
| HR (1) | HRP20240028T1 (https=) |
| HU (1) | HUE065134T2 (https=) |
| IL (2) | IL279620B2 (https=) |
| LT (1) | LT3810633T (https=) |
| MA (1) | MA52946B1 (https=) |
| MD (1) | MD3810633T2 (https=) |
| MX (1) | MX2020013811A (https=) |
| PH (1) | PH12020552240A1 (https=) |
| PL (1) | PL3810633T3 (https=) |
| PT (1) | PT3810633T (https=) |
| RS (1) | RS65128B1 (https=) |
| SG (1) | SG11202012747VA (https=) |
| SI (1) | SI3810633T1 (https=) |
| TW (2) | TW202446783A (https=) |
| UA (1) | UA128162C2 (https=) |
| WO (1) | WO2020002325A1 (https=) |
| ZA (1) | ZA202301937B (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107108699A (zh) | 2014-11-26 | 2017-08-29 | 新药物许可控股有限公司 | 化合物 |
| MD3810633T2 (ro) * | 2018-06-25 | 2024-05-31 | Spero Therapeutics Inc | Compuşi |
| TW202233649A (zh) | 2020-11-06 | 2022-09-01 | 美商斯佩羅治療學股份有限公司 | 化合物 |
| WO2022262823A1 (zh) * | 2021-06-18 | 2022-12-22 | 华南理工大学 | 活性氧自由基响应的多粘菌素前药化合物及其应用 |
| CN120574287A (zh) * | 2025-06-10 | 2025-09-02 | 中国药科大学 | 一种抗菌肽、组合物及应用 |
| CN120518715B (zh) * | 2025-07-24 | 2025-10-03 | 中国药科大学 | 一种抗菌肽、药物组合物及应用 |
| CN120699105B (zh) * | 2025-08-19 | 2025-11-21 | 中国药科大学 | 一种氘代抗菌肽及其组合物和应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2128617A (en) | 1982-10-06 | 1984-05-02 | Martti Vaara | Polypeptides for use in antibacterial therapy |
| WO1988000950A2 (fr) | 1986-08-06 | 1988-02-11 | Fauchere Jean Luc | Fabrication de conjugues a liaisons de covalence a partir d'un antibiotique et d'un derive non toxique de la polymyxine b |
| US20010021697A1 (en) | 1987-09-14 | 2001-09-13 | Henning Lowenstein | Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom, proteinageous or polypeptide components thereof, or analogues of such proteinaceous or polypeptide components |
| TW274552B (https=) | 1992-05-26 | 1996-04-21 | Hoechst Ag | |
| US5767068A (en) | 1997-02-13 | 1998-06-16 | Pathogenesis Corporation | Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections |
| AU2004277977B2 (en) | 2003-09-30 | 2010-10-28 | Biomechanisms Inc. | Compositions and methods for treating burns |
| US20060004185A1 (en) | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
| US7807637B2 (en) | 2006-08-11 | 2010-10-05 | Northern Antibiotics Oy | Polymyxin derivatives and uses thereof |
| HUE028271T2 (en) | 2006-08-11 | 2016-12-28 | Northern Antibiotics Oy | Polymixin derivatives and their applications |
| FI20085469A0 (fi) | 2008-02-08 | 2008-05-16 | Northern Antibiotics Oy | Polymyksiinijohdannaiset, joissa on lyhyt rasvahappohäntä, ja niiden käyttöjä |
| US8193148B2 (en) | 2008-02-08 | 2012-06-05 | Northern Antibiotics Ltd. | Short fatty acid tail polymyxin derivatives and uses thereof |
| US8329645B2 (en) | 2008-02-08 | 2012-12-11 | Northern Antibiotics Ltd. | Polymyxin derivatives and uses thereof |
| ES2334547B1 (es) | 2008-09-10 | 2010-12-03 | Universidad De Barcelona | Compuestos peptidicos antibacterianos. |
| TW201035111A (en) | 2008-12-23 | 2010-10-01 | Biosource Pharm Inc | Antibiotic compositions for the treatment of gram negative infections |
| CN101851270A (zh) | 2009-04-03 | 2010-10-06 | 梁浩 | 一种多粘菌素衍生物及其制备方法 |
| WO2010130007A1 (en) | 2009-05-14 | 2010-11-18 | Monash University | Antimicrobial compounds |
| US8415307B1 (en) | 2010-06-23 | 2013-04-09 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| WO2012051663A1 (en) | 2010-10-21 | 2012-04-26 | Monash University | Antimicrobial compounds |
| WO2012168820A1 (en) * | 2011-06-08 | 2012-12-13 | Pfizer Inc. | Polymyxin derivatives useful as antibacterial agents |
| BR112014012016A2 (pt) | 2011-11-18 | 2017-05-16 | Cantab Anti-Infectives Ltd | compostos |
| JP6643758B2 (ja) | 2013-05-22 | 2020-02-12 | スペロ・セラピューティクス・インコーポレーテッド | 異なった抗生物質と一緒の組合せ療法におけるポリミキシン誘導体及びその使用 |
| RU2740190C2 (ru) | 2014-03-11 | 2021-01-12 | Сперо Терапьютикс, Инк. | Производные полимиксина и их применение в комбинированной терапии совместно с различными антибиотиками |
| US10047126B2 (en) | 2014-04-01 | 2018-08-14 | Monash University | Polymyxin derivatives as antimicrobial compounds |
| CN107108699A (zh) | 2014-11-26 | 2017-08-29 | 新药物许可控股有限公司 | 化合物 |
| KR20170098821A (ko) * | 2014-12-17 | 2017-08-30 | 에프. 호프만-라 로슈 아게 | 소르타아제를 사용한 １ 단계로의 이중 폴리펩티드 컨쥬게이션을 위한 효소 원-포트 반응 |
| WO2016166103A1 (en) * | 2015-04-13 | 2016-10-20 | Xellia Pharmaceuticals Aps | Polymyxin derivatives |
| EP3356387B1 (en) * | 2015-09-29 | 2024-06-26 | Monash University | Antimicrobial polymyxin derivative compounds |
| AU2017285424B2 (en) * | 2016-06-16 | 2022-08-18 | International Aids Vaccine Initiative, Inc. | Tuberculosis compositions and methods of treating or preventing tuberculosis |
| MD3810633T2 (ro) * | 2018-06-25 | 2024-05-31 | Spero Therapeutics Inc | Compuşi |
| WO2020014501A1 (en) | 2018-07-11 | 2020-01-16 | Cidara Therapeutics, Inc. | Compositions and methods for the treatment of bacterial infections |
-
2019
- 2019-06-25 MD MDE20210390T patent/MD3810633T2/ro unknown
- 2019-06-25 EP EP19734346.0A patent/EP3810633B1/en active Active
- 2019-06-25 TW TW113126533A patent/TW202446783A/zh unknown
- 2019-06-25 AR ARP190101764A patent/AR116663A1/es unknown
- 2019-06-25 FI FIEP19734346.0T patent/FI3810633T3/fi active
- 2019-06-25 BR BR112020026663-9A patent/BR112020026663A2/pt unknown
- 2019-06-25 PT PT197343460T patent/PT3810633T/pt unknown
- 2019-06-25 AU AU2019294261A patent/AU2019294261B2/en active Active
- 2019-06-25 MA MA52946A patent/MA52946B1/fr unknown
- 2019-06-25 RS RS20240128A patent/RS65128B1/sr unknown
- 2019-06-25 MX MX2020013811A patent/MX2020013811A/es unknown
- 2019-06-25 CA CA3103158A patent/CA3103158A1/en active Pending
- 2019-06-25 ES ES19734346T patent/ES2971732T3/es active Active
- 2019-06-25 EP EP23215457.5A patent/EP4316504A3/en active Pending
- 2019-06-25 DK DK19734346.0T patent/DK3810633T3/da active
- 2019-06-25 CN CN201980041706.3A patent/CN112789287B/zh active Active
- 2019-06-25 PL PL19734346.0T patent/PL3810633T3/pl unknown
- 2019-06-25 US US17/253,426 patent/US11459357B2/en active Active
- 2019-06-25 IL IL279620A patent/IL279620B2/en unknown
- 2019-06-25 KR KR1020217000402A patent/KR20210054500A/ko active Pending
- 2019-06-25 CN CN202410703525.5A patent/CN118878638A/zh active Pending
- 2019-06-25 UA UAA202008220A patent/UA128162C2/uk unknown
- 2019-06-25 SI SI201930707T patent/SI3810633T1/sl unknown
- 2019-06-25 EA EA202092819A patent/EA202092819A1/ru unknown
- 2019-06-25 HR HRP20240028TT patent/HRP20240028T1/hr unknown
- 2019-06-25 LT LTEPPCT/EP2019/066819T patent/LT3810633T/lt unknown
- 2019-06-25 JP JP2020571762A patent/JP7488774B2/ja active Active
- 2019-06-25 SG SG11202012747VA patent/SG11202012747VA/en unknown
- 2019-06-25 TW TW108122117A patent/TWI851584B/zh active
- 2019-06-25 HU HUE19734346A patent/HUE065134T2/hu unknown
- 2019-06-25 WO PCT/EP2019/066819 patent/WO2020002325A1/en not_active Ceased
-
2020
- 2020-12-21 PH PH12020552240A patent/PH12020552240A1/en unknown
- 2020-12-22 CO CONC2020/0016080A patent/CO2020016080A2/es unknown
-
2022
- 2022-08-23 US US17/893,944 patent/US12528837B2/en active Active
-
2023
- 2023-02-06 ZA ZA2023/01937A patent/ZA202301937B/en unknown
-
2024
- 2024-05-10 JP JP2024077064A patent/JP2024109664A/ja active Pending
- 2024-05-21 AU AU2024203362A patent/AU2024203362A1/en active Pending
-
2025
- 2025-09-25 IL IL323560A patent/IL323560A/en unknown
- 2025-12-10 US US19/415,229 patent/US20260103491A1/en active Pending
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