HRP20240028T1 - Spojevi - Google Patents
Spojevi Download PDFInfo
- Publication number
- HRP20240028T1 HRP20240028T1 HRP20240028TT HRP20240028T HRP20240028T1 HR P20240028 T1 HRP20240028 T1 HR P20240028T1 HR P20240028T T HRP20240028T T HR P20240028TT HR P20240028 T HRP20240028 T HR P20240028T HR P20240028 T1 HRP20240028 T1 HR P20240028T1
- Authority
- HR
- Croatia
- Prior art keywords
- compound
- spp
- pharmaceutical preparation
- bacteria
- solvates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
- C07K7/62—Polymyxins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862689602P | 2018-06-25 | 2018-06-25 | |
| EP19734346.0A EP3810633B1 (en) | 2018-06-25 | 2019-06-25 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20240028T1 true HRP20240028T1 (hr) | 2024-03-29 |
Family
ID=67107423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20240028TT HRP20240028T1 (hr) | 2018-06-25 | 2019-06-25 | Spojevi |
Country Status (31)
| Country | Link |
|---|---|
| US (3) | US11459357B2 (https=) |
| EP (2) | EP4316504A3 (https=) |
| JP (2) | JP7488774B2 (https=) |
| KR (1) | KR20210054500A (https=) |
| CN (2) | CN112789287B (https=) |
| AR (1) | AR116663A1 (https=) |
| AU (2) | AU2019294261B2 (https=) |
| BR (1) | BR112020026663A2 (https=) |
| CA (1) | CA3103158A1 (https=) |
| CO (1) | CO2020016080A2 (https=) |
| DK (1) | DK3810633T3 (https=) |
| EA (1) | EA202092819A1 (https=) |
| ES (1) | ES2971732T3 (https=) |
| FI (1) | FI3810633T3 (https=) |
| HR (1) | HRP20240028T1 (https=) |
| HU (1) | HUE065134T2 (https=) |
| IL (2) | IL279620B2 (https=) |
| LT (1) | LT3810633T (https=) |
| MA (1) | MA52946B1 (https=) |
| MD (1) | MD3810633T2 (https=) |
| MX (1) | MX2020013811A (https=) |
| PH (1) | PH12020552240A1 (https=) |
| PL (1) | PL3810633T3 (https=) |
| PT (1) | PT3810633T (https=) |
| RS (1) | RS65128B1 (https=) |
| SG (1) | SG11202012747VA (https=) |
| SI (1) | SI3810633T1 (https=) |
| TW (2) | TWI851584B (https=) |
| UA (1) | UA128162C2 (https=) |
| WO (1) | WO2020002325A1 (https=) |
| ZA (1) | ZA202301937B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12146004B2 (en) | 2014-11-26 | 2024-11-19 | Spero Therapeutics, Inc. | Polymyxin compounds and uses thereof |
| RS65128B1 (sr) * | 2018-06-25 | 2024-02-29 | Spero Therapeutics Inc | Jedinjenja |
| WO2022098950A1 (en) | 2020-11-06 | 2022-05-12 | Spero Therapeutics, Inc. | Compounds |
| WO2022262823A1 (zh) * | 2021-06-18 | 2022-12-22 | 华南理工大学 | 活性氧自由基响应的多粘菌素前药化合物及其应用 |
| CN121426894A (zh) * | 2025-07-24 | 2026-01-30 | 中国药科大学 | 一种抗菌肽、药物组合物及应用 |
| CN120699105B (zh) * | 2025-08-19 | 2025-11-21 | 中国药科大学 | 一种氘代抗菌肽及其组合物和应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2128617A (en) | 1982-10-06 | 1984-05-02 | Martti Vaara | Polypeptides for use in antibacterial therapy |
| AU7753787A (en) | 1986-08-06 | 1988-02-24 | Jean-Luc Fauchere | Production of covalent-linked conjugates from an antibiotic and a non-toxic derivative of polymyxine b |
| US20010021697A1 (en) | 1987-09-14 | 2001-09-13 | Henning Lowenstein | Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom, proteinageous or polypeptide components thereof, or analogues of such proteinaceous or polypeptide components |
| TW274552B (https=) | 1992-05-26 | 1996-04-21 | Hoechst Ag | |
| US5767068A (en) | 1997-02-13 | 1998-06-16 | Pathogenesis Corporation | Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections |
| CA2540742A1 (en) | 2003-09-30 | 2005-04-14 | Terry Hicks | Compositions and methods for treating burns |
| US20060004185A1 (en) | 2004-07-01 | 2006-01-05 | Leese Richard A | Peptide antibiotics and peptide intermediates for their prepartion |
| BRPI0715095B8 (pt) | 2006-08-11 | 2021-05-25 | Northern Antibiotics Oy | derivado de polimixina da fórmula geral (i); produto de combinação; composição farmacêutica; método para se sensibilizar bactérias gram-negativas a um agente antibacteriano; método para o desenvolvimento de antibióticos; método para a redução da toxicidade de polimixinas, octapeptinas naturais e seus derivados durante a aplicação das mesmas no tratamento de infecções em um indivíduo; método para melhorar as propriedades farmacocinéticas, de polimixinas, octapeptinas naturais e seus derivados; método para a sensibilização de bactérias gram-negativas clinicamente importantes a um complemento de mecanismo de defesa presente no soro; uso de um derivado; e processo para a preparação de um derivado de polimixina da fórmula (i). |
| US7807637B2 (en) | 2006-08-11 | 2010-10-05 | Northern Antibiotics Oy | Polymyxin derivatives and uses thereof |
| FI20085469A0 (fi) | 2008-02-08 | 2008-05-16 | Northern Antibiotics Oy | Polymyksiinijohdannaiset, joissa on lyhyt rasvahappohäntä, ja niiden käyttöjä |
| US8193148B2 (en) | 2008-02-08 | 2012-06-05 | Northern Antibiotics Ltd. | Short fatty acid tail polymyxin derivatives and uses thereof |
| US8329645B2 (en) | 2008-02-08 | 2012-12-11 | Northern Antibiotics Ltd. | Polymyxin derivatives and uses thereof |
| ES2334547B1 (es) | 2008-09-10 | 2010-12-03 | Universidad De Barcelona | Compuestos peptidicos antibacterianos. |
| CA2747995A1 (en) | 2008-12-23 | 2010-07-01 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| CN101851270A (zh) | 2009-04-03 | 2010-10-06 | 梁浩 | 一种多粘菌素衍生物及其制备方法 |
| WO2010130007A1 (en) | 2009-05-14 | 2010-11-18 | Monash University | Antimicrobial compounds |
| US8415307B1 (en) | 2010-06-23 | 2013-04-09 | Biosource Pharm, Inc. | Antibiotic compositions for the treatment of gram negative infections |
| WO2012051663A1 (en) | 2010-10-21 | 2012-04-26 | Monash University | Antimicrobial compounds |
| WO2012168820A1 (en) * | 2011-06-08 | 2012-12-13 | Pfizer Inc. | Polymyxin derivatives useful as antibacterial agents |
| CA2855916A1 (en) | 2011-11-18 | 2013-05-23 | Novacta Biosystems Limited | Polymyxin derivatives |
| KR102354902B1 (ko) | 2013-05-22 | 2022-01-24 | 에버레스트 메디신즈 (싱가포르) 피티이. 리미티드 | 폴리믹신 유도체 및 상이한 항생제와의 조합 요법에 있어서의 이들의 용도 |
| MX359104B (es) | 2014-03-11 | 2018-09-14 | New Pharma Licence Holdings Ltd | Derivados de polimixina y su uso en terapia de combinacion junto con diferentes antibioticos. |
| JP2017512818A (ja) | 2014-04-01 | 2017-05-25 | モナシュ、ユニバーシティＭｏｎａｓｈ Ｕｎｉｖｅｒｓｉｔｙ | 抗菌性化合物としてのポリミキシン誘導体 |
| US12146004B2 (en) | 2014-11-26 | 2024-11-19 | Spero Therapeutics, Inc. | Polymyxin compounds and uses thereof |
| SG11201704627XA (en) * | 2014-12-17 | 2017-07-28 | Hoffmann La Roche | Enzymatic one-pot reaction for double polypeptide conjugation in a single step using sortase |
| WO2016166103A1 (en) * | 2015-04-13 | 2016-10-20 | Xellia Pharmaceuticals Aps | Polymyxin derivatives |
| EP3356387B1 (en) * | 2015-09-29 | 2024-06-26 | Monash University | Antimicrobial polymyxin derivative compounds |
| US10428122B2 (en) * | 2016-06-16 | 2019-10-01 | International Aids Vaccine Initiative, Inc. | Tuberculosis compositions and methods of treating or preventing tuberculosis |
| RS65128B1 (sr) * | 2018-06-25 | 2024-02-29 | Spero Therapeutics Inc | Jedinjenja |
| WO2020014501A1 (en) | 2018-07-11 | 2020-01-16 | Cidara Therapeutics, Inc. | Compositions and methods for the treatment of bacterial infections |
-
2019
- 2019-06-25 RS RS20240128A patent/RS65128B1/sr unknown
- 2019-06-25 PT PT197343460T patent/PT3810633T/pt unknown
- 2019-06-25 TW TW108122117A patent/TWI851584B/zh active
- 2019-06-25 FI FIEP19734346.0T patent/FI3810633T3/fi active
- 2019-06-25 MA MA52946A patent/MA52946B1/fr unknown
- 2019-06-25 SI SI201930707T patent/SI3810633T1/sl unknown
- 2019-06-25 EA EA202092819A patent/EA202092819A1/ru unknown
- 2019-06-25 TW TW113126533A patent/TW202446783A/zh unknown
- 2019-06-25 ES ES19734346T patent/ES2971732T3/es active Active
- 2019-06-25 IL IL279620A patent/IL279620B2/en unknown
- 2019-06-25 UA UAA202008220A patent/UA128162C2/uk unknown
- 2019-06-25 LT LTEPPCT/EP2019/066819T patent/LT3810633T/lt unknown
- 2019-06-25 MX MX2020013811A patent/MX2020013811A/es unknown
- 2019-06-25 HR HRP20240028TT patent/HRP20240028T1/hr unknown
- 2019-06-25 EP EP23215457.5A patent/EP4316504A3/en active Pending
- 2019-06-25 PL PL19734346.0T patent/PL3810633T3/pl unknown
- 2019-06-25 EP EP19734346.0A patent/EP3810633B1/en active Active
- 2019-06-25 CN CN201980041706.3A patent/CN112789287B/zh active Active
- 2019-06-25 DK DK19734346.0T patent/DK3810633T3/da active
- 2019-06-25 AU AU2019294261A patent/AU2019294261B2/en active Active
- 2019-06-25 JP JP2020571762A patent/JP7488774B2/ja active Active
- 2019-06-25 BR BR112020026663-9A patent/BR112020026663A2/pt unknown
- 2019-06-25 CN CN202410703525.5A patent/CN118878638A/zh active Pending
- 2019-06-25 US US17/253,426 patent/US11459357B2/en active Active
- 2019-06-25 WO PCT/EP2019/066819 patent/WO2020002325A1/en not_active Ceased
- 2019-06-25 CA CA3103158A patent/CA3103158A1/en active Pending
- 2019-06-25 KR KR1020217000402A patent/KR20210054500A/ko active Pending
- 2019-06-25 AR ARP190101764A patent/AR116663A1/es unknown
- 2019-06-25 HU HUE19734346A patent/HUE065134T2/hu unknown
- 2019-06-25 MD MDE20210390T patent/MD3810633T2/ro unknown
- 2019-06-25 SG SG11202012747VA patent/SG11202012747VA/en unknown
-
2020
- 2020-12-21 PH PH12020552240A patent/PH12020552240A1/en unknown
- 2020-12-22 CO CONC2020/0016080A patent/CO2020016080A2/es unknown
-
2022
- 2022-08-23 US US17/893,944 patent/US12528837B2/en active Active
-
2023
- 2023-02-06 ZA ZA2023/01937A patent/ZA202301937B/en unknown
-
2024
- 2024-05-10 JP JP2024077064A patent/JP2024109664A/ja active Pending
- 2024-05-21 AU AU2024203362A patent/AU2024203362A1/en active Pending
-
2025
- 2025-09-25 IL IL323560A patent/IL323560A/en unknown
- 2025-12-10 US US19/415,229 patent/US20260103491A1/en active Pending
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