FI3359572T3 - Menetelmä multippeliskleroosin hoitamiseksi - Google Patents
Menetelmä multippeliskleroosin hoitamiseksi Download PDFInfo
- Publication number
- FI3359572T3 FI3359572T3 FIEP16790464.8T FI16790464T FI3359572T3 FI 3359572 T3 FI3359572 T3 FI 3359572T3 FI 16790464 T FI16790464 T FI 16790464T FI 3359572 T3 FI3359572 T3 FI 3359572T3
- Authority
- FI
- Finland
- Prior art keywords
- antibody
- exposure
- use according
- dose
- patient
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 3
- 201000006417 multiple sclerosis Diseases 0.000 title claims 3
- 102100022005 B-lymphocyte antigen CD20 Human genes 0.000 claims 31
- 101000897405 Homo sapiens B-lymphocyte antigen CD20 Proteins 0.000 claims 31
- VKZRWSNIWNFCIQ-WDSKDSINSA-N (2s)-2-[2-[[(1s)-1,2-dicarboxyethyl]amino]ethylamino]butanedioic acid Chemical compound OC(=O)C[C@@H](C(O)=O)NCCN[C@H](C(O)=O)CC(O)=O VKZRWSNIWNFCIQ-WDSKDSINSA-N 0.000 claims 2
- 208000007118 chronic progressive multiple sclerosis Diseases 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 206010063401 primary progressive multiple sclerosis Diseases 0.000 claims 2
- 230000003902 lesion Effects 0.000 claims 1
- 229950005751 ocrelizumab Drugs 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Preliminary Treatment Of Fibers (AREA)
- Spinning Or Twisting Of Yarns (AREA)
- Treatment Of Fiber Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562238103P | 2015-10-06 | 2015-10-06 | |
| US201562238674P | 2015-10-07 | 2015-10-07 | |
| US201562271985P | 2015-12-28 | 2015-12-28 | |
| US201662296049P | 2016-02-16 | 2016-02-16 | |
| US201662322734P | 2016-04-14 | 2016-04-14 | |
| US201662342633P | 2016-05-27 | 2016-05-27 | |
| US201662355299P | 2016-06-27 | 2016-06-27 | |
| PCT/US2016/055841 WO2017062682A2 (en) | 2015-10-06 | 2016-10-06 | Method for treating multiple sclerosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI3359572T3 true FI3359572T3 (fi) | 2025-01-27 |
Family
ID=57223757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP16790464.8T FI3359572T3 (fi) | 2015-10-06 | 2016-10-06 | Menetelmä multippeliskleroosin hoitamiseksi |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US20180327505A1 (enExample) |
| EP (2) | EP3359572B1 (enExample) |
| JP (4) | JP2018529747A (enExample) |
| KR (2) | KR20240107346A (enExample) |
| CN (1) | CN108431038A (enExample) |
| DK (1) | DK3359572T3 (enExample) |
| ES (1) | ES3007182T3 (enExample) |
| FI (1) | FI3359572T3 (enExample) |
| HK (1) | HK1257072A1 (enExample) |
| HR (1) | HRP20250052T1 (enExample) |
| HU (1) | HUE069935T2 (enExample) |
| IL (2) | IL258506A (enExample) |
| LT (1) | LT3359572T (enExample) |
| PL (1) | PL3359572T3 (enExample) |
| PT (1) | PT3359572T (enExample) |
| RS (1) | RS66408B1 (enExample) |
| SI (1) | SI3359572T1 (enExample) |
| WO (1) | WO2017062682A2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023515528A (ja) * | 2020-02-28 | 2023-04-13 | ジェネンテック, インコーポレイテッド | ブルトン型チロシンキナーゼの阻害剤を使用する一次性進行型多発性硬化症の治療方法 |
| EP4196223A1 (en) * | 2020-08-14 | 2023-06-21 | F. Hoffmann-La Roche AG | Methods for treating multiple sclerosis with ocrelizumab |
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| EP1753455A2 (en) | 2004-06-04 | 2007-02-21 | Genentech, Inc. | Method for treating multiple sclerosis |
| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| GB0718684D0 (en) * | 2007-09-24 | 2007-10-31 | Roche Products Ltd | Treatment method |
| TW201438738A (zh) * | 2008-09-16 | 2014-10-16 | Genentech Inc | 治療進展型多發性硬化症之方法 |
| JP2014506258A (ja) * | 2011-01-10 | 2014-03-13 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | 新規使用 |
| EP2530088A1 (en) * | 2011-05-30 | 2012-12-05 | Klinikum rechts der Isar der Technischen Universität München | Means and methods for diagnosing and treating multiple sclerosis |
-
2016
- 2016-10-06 HR HRP20250052TT patent/HRP20250052T1/hr unknown
- 2016-10-06 SI SI201631885T patent/SI3359572T1/sl unknown
- 2016-10-06 JP JP2018517617A patent/JP2018529747A/ja active Pending
- 2016-10-06 EP EP16790464.8A patent/EP3359572B1/en active Active
- 2016-10-06 PL PL16790464.8T patent/PL3359572T3/pl unknown
- 2016-10-06 EP EP24214663.7A patent/EP4491227A3/en active Pending
- 2016-10-06 FI FIEP16790464.8T patent/FI3359572T3/fi active
- 2016-10-06 RS RS20250043A patent/RS66408B1/sr unknown
- 2016-10-06 KR KR1020247020490A patent/KR20240107346A/ko active Pending
- 2016-10-06 PT PT167904648T patent/PT3359572T/pt unknown
- 2016-10-06 HK HK18116241.3A patent/HK1257072A1/zh unknown
- 2016-10-06 ES ES16790464T patent/ES3007182T3/es active Active
- 2016-10-06 DK DK16790464.8T patent/DK3359572T3/da active
- 2016-10-06 WO PCT/US2016/055841 patent/WO2017062682A2/en not_active Ceased
- 2016-10-06 LT LTEPPCT/US2016/055841T patent/LT3359572T/lt unknown
- 2016-10-06 CN CN201680069743.1A patent/CN108431038A/zh active Pending
- 2016-10-06 HU HUE16790464A patent/HUE069935T2/hu unknown
- 2016-10-06 KR KR1020187012496A patent/KR20180075537A/ko not_active Ceased
-
2018
- 2018-04-05 US US15/946,465 patent/US20180327505A1/en not_active Abandoned
- 2018-04-05 IL IL258506A patent/IL258506A/en unknown
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2021
- 2021-03-16 US US17/203,671 patent/US20210388099A1/en not_active Abandoned
- 2021-05-28 JP JP2021090543A patent/JP2021152026A/ja not_active Withdrawn
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2022
- 2022-06-08 IL IL293708A patent/IL293708B1/en unknown
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2023
- 2023-06-07 JP JP2023093742A patent/JP2023123521A/ja active Pending
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2024
- 2024-02-28 US US18/590,267 patent/US20240327536A1/en active Pending
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2025
- 2025-08-13 JP JP2025134905A patent/JP2025170299A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20240107346A (ko) | 2024-07-09 |
| EP4491227A2 (en) | 2025-01-15 |
| JP2025170299A (ja) | 2025-11-18 |
| JP2021152026A (ja) | 2021-09-30 |
| ES3007182T3 (en) | 2025-03-19 |
| WO2017062682A8 (en) | 2018-02-01 |
| JP2018529747A (ja) | 2018-10-11 |
| HRP20250052T1 (hr) | 2025-03-14 |
| IL293708B1 (en) | 2025-12-01 |
| EP4491227A3 (en) | 2025-04-23 |
| DK3359572T3 (da) | 2025-01-27 |
| LT3359572T (lt) | 2025-02-10 |
| WO2017062682A2 (en) | 2017-04-13 |
| US20180327505A1 (en) | 2018-11-15 |
| SI3359572T1 (sl) | 2025-03-31 |
| PL3359572T3 (pl) | 2025-03-17 |
| JP2023123521A (ja) | 2023-09-05 |
| HK1257072A1 (zh) | 2019-10-11 |
| HUE069935T2 (hu) | 2025-04-28 |
| WO2017062682A3 (en) | 2017-05-26 |
| IL293708A (en) | 2022-08-01 |
| PT3359572T (pt) | 2025-01-27 |
| EP3359572A2 (en) | 2018-08-15 |
| US20240327536A1 (en) | 2024-10-03 |
| IL258506A (en) | 2018-05-31 |
| CN108431038A (zh) | 2018-08-21 |
| US20210388099A1 (en) | 2021-12-16 |
| RS66408B1 (sr) | 2025-02-28 |
| KR20180075537A (ko) | 2018-07-04 |
| EP3359572B1 (en) | 2024-11-27 |
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