FI2970903T3 - Pluripotenteista kantasoluista tuotettuja fotoreseptoreita ja fotoreseptoreiden esiasteita - Google Patents

Pluripotenteista kantasoluista tuotettuja fotoreseptoreita ja fotoreseptoreiden esiasteita Download PDF

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FI2970903T3
FI2970903T3 FIEP14764825.7T FI14764825T FI2970903T3 FI 2970903 T3 FI2970903 T3 FI 2970903T3 FI 14764825 T FI14764825 T FI 14764825T FI 2970903 T3 FI2970903 T3 FI 2970903T3
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cells
photoreceptor
progenitors
cell
conditions
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FIEP14764825.7T
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Finnish (fi)
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Robert Lanza
Shi-Jiang Lu
Wei Wang
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Astellas Inst For Regenerative Medicine
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/062—Sensory transducers, e.g. photoreceptors; Sensory neurons, e.g. for hearing, taste, smell, pH, touch, temperature, pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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FIEP14764825.7T 2013-03-15 2014-03-14 Pluripotenteista kantasoluista tuotettuja fotoreseptoreita ja fotoreseptoreiden esiasteita FI2970903T3 (fi)

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US201361793168P 2013-03-15 2013-03-15
PCT/US2014/029790 WO2014145108A1 (en) 2013-03-15 2014-03-14 Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells

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US (5) US20160030490A1 (enExample)
EP (2) EP4292600A3 (enExample)
JP (4) JP6581966B2 (enExample)
KR (3) KR102263956B1 (enExample)
CN (2) CN118995611A (enExample)
AU (3) AU2014233403B2 (enExample)
CA (2) CA2906815A1 (enExample)
DK (1) DK2970903T3 (enExample)
ES (1) ES2970720T3 (enExample)
FI (1) FI2970903T3 (enExample)
HK (1) HK1222205A1 (enExample)
IL (5) IL294897B2 (enExample)
PT (1) PT2970903T (enExample)
WO (1) WO2014145108A1 (enExample)

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AU2014233403B2 (en) 2013-03-15 2019-08-01 Astellas Institute For Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
US11241460B2 (en) 2013-03-15 2022-02-08 Astellas Institute For Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
EP4343331A3 (en) * 2015-03-23 2024-06-19 Astellas Institute for Regenerative Medicine Improved assays for potency of human retinal pigment epithelium (rpe) cells and photoreceptor progenitors
TWI711455B (zh) * 2015-05-13 2020-12-01 臺北榮民總醫院 多層視網膜細胞移植物
AU2016308818B2 (en) 2015-08-18 2022-04-21 Astellas Institute For Regenerative Medicine Clinical formulations
ES2922475T3 (es) 2015-09-08 2022-09-15 Sumitomo Pharma Co Ltd Método para producir células epiteliales pigmentarias de la retina
CN105567635A (zh) * 2016-02-21 2016-05-11 中国医科大学附属第一医院 一种改良的Neurobasal B27培养基、制备方法及应用
US11920155B2 (en) 2016-03-30 2024-03-05 Asterias Biotherapeutics, Inc. Oligodendrocyte progenitor cell compositions
EP3824906A1 (en) 2016-12-21 2021-05-26 Amgen Inc. Anti-tnf alpha antibody formulations
IL268666B2 (en) * 2017-02-17 2025-06-01 Univ Sorbonne Feeder-free methods for obtaining retinal progenitors, retinal pigmented epithelial cells and neural retinal cells
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CA3055706A1 (en) 2017-03-08 2018-09-13 Sumitomo Dainippon Pharma Co., Ltd. Method for producing retinal pigment epithelial cells
US20200277571A1 (en) * 2017-09-14 2020-09-03 Riken Method for amplifying cone photoreceptors or rod photoreceptors using dorsalization signal transmitter or ventralization signal transmitter
US12090252B2 (en) 2017-09-14 2024-09-17 Riken Method for producing retinal tissues
WO2019078781A1 (en) * 2017-10-17 2019-04-25 National University Of Singapore SYSTEMS AND METHODS FOR PRODUCING PHOTORECEPTOR PROGENITORS
AU2019256723B2 (en) 2018-04-20 2025-09-04 FUJIFILM Cellular Dynamics, Inc. Method for differentiation of ocular cells and use thereof
CN108795864B (zh) * 2018-05-24 2021-08-24 中山大学中山眼科中心 一种利用人诱导多能干细胞获得富含视锥及视杆细胞的类视网膜组织的方法
AU2019335025A1 (en) * 2018-09-07 2021-04-08 Hebecell Corporation Methods and compositions for retinal neuron generation in carrier-free 3D sphere suspension culture
US12365872B2 (en) 2018-09-19 2025-07-22 Lineage Cell Therapeutics, Inc. Methods for differentiating pluripotent stem cells in dynamic suspension culture
CN109486766B (zh) * 2018-11-26 2021-05-07 中山大学 一种泪腺干细胞、泪腺干细胞的培养体系和培养方法
US11603518B2 (en) 2019-01-23 2023-03-14 Asterias Biotherapeutics, Inc. Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells
US20230212509A1 (en) * 2020-05-29 2023-07-06 FUJIFILM Cellular Dynamics, Inc. Bilayer of retinal pigmented epithelium and photoreceptors and use thereof
JP2023528377A (ja) * 2020-05-29 2023-07-04 フジフィルム セルラー ダイナミクス，インコーポレイテッド 網膜色素上皮及び光受容体の二重細胞凝集体、並びにその使用方法
CN112608883B (zh) * 2020-12-25 2023-02-24 武汉睿健医药科技有限公司 一种光感受器神经元细胞的化学诱导方法
EP4269564A4 (en) * 2020-12-25 2025-03-05 Iregene Therapeutics Ltd CHEMICAL INDUCTION METHOD FOR PHOTORECEPTOR NEURONAL CELLS
KR102525093B1 (ko) * 2021-04-16 2023-04-27 가톨릭대학교 산학협력단 사람 신경능 유래 코 하비갑개 줄기세포를 유효성분으로 포함하는 망막변성질환 예방 또는 치료용 약학적 조성물
CN113388582A (zh) * 2021-06-21 2021-09-14 香港再生医学有限公司 促使iPSC分化为外周神经干细胞的方法及培养基和系统

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JP6223963B2 (ja) 2011-05-18 2017-11-01 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 網膜疾患を処置するための組成物および方法
ES2688019T3 (es) * 2012-06-05 2018-10-30 The Regents Of The University Of California Métodos y composiciones para la producción acelerada de células epiteliales pigmentadas retinianas a partir de células pluripotentes
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AU2014233403B2 (en) 2013-03-15 2019-08-01 Astellas Institute For Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
US20160175362A1 (en) 2014-03-14 2016-06-23 Ocata Therapeutics, Inc. Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells

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ES2970720T3 (es) 2024-05-30
EP4292600A3 (en) 2024-04-10
JP7245752B2 (ja) 2023-03-24
AU2019253874A1 (en) 2019-11-14
CN118995611A (zh) 2024-11-22
IL307568A (en) 2023-12-01
DK2970903T3 (da) 2024-02-19
KR20160002779A (ko) 2016-01-08
EP2970903A1 (en) 2016-01-20
KR20230058556A (ko) 2023-05-03
JP2024053564A (ja) 2024-04-15
IL294897B1 (en) 2023-11-01
HK1218931A1 (en) 2017-03-17
KR102527507B1 (ko) 2023-04-28
IL294897B2 (en) 2024-03-01
IL294897A (en) 2022-09-01
US20140294778A1 (en) 2014-10-02
IL276173A (en) 2020-09-30
JP2016515382A (ja) 2016-05-30
KR102263956B1 (ko) 2021-06-11
IL266775B (en) 2020-08-31
PT2970903T (pt) 2024-02-26
US20160030490A1 (en) 2016-02-04
HK1222205A1 (zh) 2017-06-23
AU2014233403B2 (en) 2019-08-01
IL241177A0 (en) 2015-11-30
CN105378070A (zh) 2016-03-02
US20220347228A1 (en) 2022-11-03
US20190290701A1 (en) 2019-09-26
WO2014145108A1 (en) 2014-09-18
JP2022023092A (ja) 2022-02-07
IL276173B2 (en) 2023-02-01
JP2020031635A (ja) 2020-03-05
US20190321414A1 (en) 2019-10-24
IL266775A (en) 2019-07-31
JP6581966B2 (ja) 2019-09-25
AU2022201986B2 (en) 2025-09-18
IL276173B (en) 2022-10-01
IL241177B (en) 2019-06-30
EP2970903B1 (en) 2023-12-13
CA3177943A1 (en) 2014-09-18
AU2014233403A1 (en) 2015-10-08
CA2906815A1 (en) 2014-09-18
US10307444B2 (en) 2019-06-04
AU2022201986A1 (en) 2022-04-14
KR20210070394A (ko) 2021-06-14
EP4292600A2 (en) 2023-12-20
EP2970903A4 (en) 2016-11-16

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