FI2970903T3 - Pluripotenteista kantasoluista tuotettuja fotoreseptoreita ja fotoreseptoreiden esiasteita - Google Patents

Pluripotenteista kantasoluista tuotettuja fotoreseptoreita ja fotoreseptoreiden esiasteita Download PDF

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FI2970903T3
FI2970903T3 FIEP14764825.7T FI14764825T FI2970903T3 FI 2970903 T3 FI2970903 T3 FI 2970903T3 FI 14764825 T FI14764825 T FI 14764825T FI 2970903 T3 FI2970903 T3 FI 2970903T3
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cells
photoreceptor
progenitors
cell
conditions
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FIEP14764825.7T
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Finnish (fi)
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Robert Lanza
Shi-Jiang Lu
Wei Wang
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Astellas Inst For Regenerative Medicine
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/062—Sensory transducers, e.g. photoreceptors; Sensory neurons, e.g. for hearing, taste, smell, pH, touch, temperature, pain
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
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    • C12N2501/38—Hormones with nuclear receptors
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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FIEP14764825.7T 2013-03-15 2014-03-14 Pluripotenteista kantasoluista tuotettuja fotoreseptoreita ja fotoreseptoreiden esiasteita FI2970903T3 (fi)

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US201361793168P 2013-03-15 2013-03-15
PCT/US2014/029790 WO2014145108A1 (en) 2013-03-15 2014-03-14 Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells

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US (5) US10307444B2 (cg-RX-API-DMAC7.html)
EP (2) EP4292600A3 (cg-RX-API-DMAC7.html)
JP (4) JP6581966B2 (cg-RX-API-DMAC7.html)
KR (3) KR102527507B1 (cg-RX-API-DMAC7.html)
CN (2) CN105378070A (cg-RX-API-DMAC7.html)
AU (3) AU2014233403B2 (cg-RX-API-DMAC7.html)
CA (2) CA3177943A1 (cg-RX-API-DMAC7.html)
DK (1) DK2970903T3 (cg-RX-API-DMAC7.html)
ES (1) ES2970720T3 (cg-RX-API-DMAC7.html)
FI (1) FI2970903T3 (cg-RX-API-DMAC7.html)
HK (1) HK1222205A1 (cg-RX-API-DMAC7.html)
IL (5) IL294897B2 (cg-RX-API-DMAC7.html)
PT (1) PT2970903T (cg-RX-API-DMAC7.html)
WO (1) WO2014145108A1 (cg-RX-API-DMAC7.html)

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EP4292600A3 (en) 2013-03-15 2024-04-10 Astellas Institute for Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
IL303401A (en) 2015-03-23 2023-08-01 Astellas Inst For Regenerative Medicine Improved assays for potency of human retinal pigment epithelium (rpe) cells and photoreceptor progenitors
US20160331867A1 (en) * 2015-05-13 2016-11-17 Taipei Veterans General Hospital Multilayered retinal cell implant
SG10201913250SA (en) 2015-08-18 2020-03-30 Astellas Inst For Regenerative Medicine Clinical formulations
CN108350421A (zh) 2015-09-08 2018-07-31 大日本住友制药株式会社 用于制备视网膜色素上皮细胞的方法
CN105567635A (zh) * 2016-02-21 2016-05-11 中国医科大学附属第一医院 一种改良的Neurobasal B27培养基、制备方法及应用
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WO2019054514A1 (ja) * 2017-09-14 2019-03-21 国立研究開発法人理化学研究所 網膜組織の製造方法
WO2019078781A1 (en) * 2017-10-17 2019-04-25 National University Of Singapore SYSTEMS AND METHODS FOR PRODUCING PHOTORECEPTOR PROGENITORS
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CN108795864B (zh) * 2018-05-24 2021-08-24 中山大学中山眼科中心 一种利用人诱导多能干细胞获得富含视锥及视杆细胞的类视网膜组织的方法
US20210315938A1 (en) * 2018-09-07 2021-10-14 Hebecell Corporation Methods and Compositions for Retinal Neuron Generation in Carrier-Free 3D Sphere Suspension Culture
CN113646422B (zh) 2018-09-19 2025-03-11 谱系细胞疗法股份有限公司 用于在动态悬浮培养中分化多能干细胞的方法
CN109486766B (zh) * 2018-11-26 2021-05-07 中山大学 一种泪腺干细胞、泪腺干细胞的培养体系和培养方法
SG11202107732XA (en) 2019-01-23 2021-08-30 Asterias Biotherapeutics Inc Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells
CA3180561A1 (en) * 2020-05-29 2021-12-02 Andrew DIAS Bilayer of retinal pigmented epithelium and photoreceptors and use thereof
AU2021280343A1 (en) * 2020-05-29 2022-12-08 FUJIFILM Cellular Dynamics, Inc. Retinal pigmented epithelium and photoreceptor dual cell aggregates and methods of use thereof
CN112608883B (zh) * 2020-12-25 2023-02-24 武汉睿健医药科技有限公司 一种光感受器神经元细胞的化学诱导方法
US20240052305A1 (en) * 2020-12-25 2024-02-15 Iregene Therapeutics Ltd Chemical induction method for photoreceptor neuron cells
KR102525093B1 (ko) * 2021-04-16 2023-04-27 가톨릭대학교 산학협력단 사람 신경능 유래 코 하비갑개 줄기세포를 유효성분으로 포함하는 망막변성질환 예방 또는 치료용 약학적 조성물
CN113388582A (zh) * 2021-06-21 2021-09-14 香港再生医学有限公司 促使iPSC分化为外周神经干细胞的方法及培养基和系统

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EP4292600A3 (en) 2013-03-15 2024-04-10 Astellas Institute for Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells

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ES2970720T3 (es) 2024-05-30
EP2970903B1 (en) 2023-12-13
JP7245752B2 (ja) 2023-03-24
US20140294778A1 (en) 2014-10-02
JP6581966B2 (ja) 2019-09-25
IL241177B (en) 2019-06-30
JP2022023092A (ja) 2022-02-07
CN118995611A (zh) 2024-11-22
IL266775B (en) 2020-08-31
US20160030490A1 (en) 2016-02-04
IL266775A (en) 2019-07-31
KR102263956B1 (ko) 2021-06-11
AU2022201986B2 (en) 2025-09-18
DK2970903T3 (da) 2024-02-19
JP2016515382A (ja) 2016-05-30
AU2022201986A1 (en) 2022-04-14
WO2014145108A1 (en) 2014-09-18
EP2970903A4 (en) 2016-11-16
IL276173B2 (en) 2023-02-01
IL276173B (en) 2022-10-01
CA2906815A1 (en) 2014-09-18
IL241177A0 (en) 2015-11-30
IL294897B1 (en) 2023-11-01
KR20210070394A (ko) 2021-06-14
US10307444B2 (en) 2019-06-04
KR20230058556A (ko) 2023-05-03
HK1218931A1 (en) 2017-03-17
US20190290701A1 (en) 2019-09-26
AU2014233403A1 (en) 2015-10-08
AU2019253874A1 (en) 2019-11-14
CA3177943A1 (en) 2014-09-18
AU2014233403B2 (en) 2019-08-01
IL276173A (en) 2020-09-30
HK1222205A1 (zh) 2017-06-23
EP4292600A2 (en) 2023-12-20
US20190321414A1 (en) 2019-10-24
PT2970903T (pt) 2024-02-26
IL307568A (en) 2023-12-01
KR20160002779A (ko) 2016-01-08
EP2970903A1 (en) 2016-01-20
KR102527507B1 (ko) 2023-04-28
CN105378070A (zh) 2016-03-02
EP4292600A3 (en) 2024-04-10
JP2024053564A (ja) 2024-04-15
IL294897A (en) 2022-09-01
IL294897B2 (en) 2024-03-01
JP2020031635A (ja) 2020-03-05
US20220347228A1 (en) 2022-11-03

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