FI120589B - Modifioituja Kluyveromyces-hiivoja, niiden valmistus ja käyttö sekä menetelmä yhdistelmä-DNA-proteiinien tuottamiseksi - Google Patents
Modifioituja Kluyveromyces-hiivoja, niiden valmistus ja käyttö sekä menetelmä yhdistelmä-DNA-proteiinien tuottamiseksi Download PDFInfo
- Publication number
- FI120589B FI120589B FI946076A FI946076A FI120589B FI 120589 B FI120589 B FI 120589B FI 946076 A FI946076 A FI 946076A FI 946076 A FI946076 A FI 946076A FI 120589 B FI120589 B FI 120589B
- Authority
- FI
- Finland
- Prior art keywords
- gene
- ser
- leu
- yeast
- gly
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
- C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9207785A FR2692907B1 (fr) | 1992-06-25 | 1992-06-25 | Levures kluyveromyces modifiees, preparation et utilisation. |
| FR9207785 | 1992-06-25 | ||
| PCT/FR1993/000623 WO1994000579A1 (fr) | 1992-06-25 | 1993-06-23 | Levures kluyveromyces modifiees, preparation et utilisation |
| FR9300623 | 1993-06-23 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI946076A FI946076A (fi) | 1994-12-23 |
| FI946076A0 FI946076A0 (fi) | 1994-12-23 |
| FI120589B true FI120589B (fi) | 2009-12-15 |
Family
ID=9431166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI946076A FI120589B (fi) | 1992-06-25 | 1994-12-23 | Modifioituja Kluyveromyces-hiivoja, niiden valmistus ja käyttö sekä menetelmä yhdistelmä-DNA-proteiinien tuottamiseksi |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | USRE37447E1 (de) |
| EP (1) | EP0672150B1 (de) |
| JP (1) | JPH07508166A (de) |
| AT (1) | ATE363539T1 (de) |
| AU (1) | AU4333793A (de) |
| CA (1) | CA2139117A1 (de) |
| DE (1) | DE69334143T2 (de) |
| DK (1) | DK0672150T3 (de) |
| ES (1) | ES2287928T3 (de) |
| FI (1) | FI120589B (de) |
| FR (1) | FR2692907B1 (de) |
| PT (1) | PT672150E (de) |
| WO (1) | WO1994000579A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL116696A (en) * | 1995-01-25 | 1999-08-17 | Bio Technology General Corp | Production of enzymatically active recombinant carboxypeptidase b |
| WO1997012044A2 (en) * | 1995-09-25 | 1997-04-03 | Chiron Corporation | Pichia secretory leader for protein expression |
| US6110703A (en) * | 1996-07-05 | 2000-08-29 | Novo Nordisk A/S | Method for the production of polypeptides |
| JP2000078978A (ja) * | 1998-09-04 | 2000-03-21 | Kirin Brewery Co Ltd | プロテアーゼ活性の低下したカンジダ・ボイジニ株及び異種タンパク質製造用宿主としてのその使用 |
| US7517671B2 (en) * | 2002-02-28 | 2009-04-14 | New England Biolabs, Inc. | Methods and compositions for concentrating secreted recombinant protein |
| AR107872A1 (es) * | 2016-03-16 | 2018-06-13 | Godo Sushei Co Ltd | Proteinasa b y solución de lactasa usando sus propiedades y método para producirlo |
| CA3050607A1 (en) * | 2017-02-02 | 2018-08-09 | Lallemand Hungary Liquidity Management Llc | Heterologous protease expression for improving alcoholic fermentation |
| CN113717874B (zh) * | 2021-09-27 | 2023-04-11 | 四川大学 | 一种耐高温、耐高糖的酿酒酵母菌株及其构建方法和应用 |
| WO2023215221A2 (en) * | 2022-05-02 | 2023-11-09 | North Carolina State University | Engineered microorganisms with enhanced protein expression and secretion |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0240224A3 (de) * | 1986-03-31 | 1989-02-01 | Interferon Sciences, Inc. | Alpha-Interferon-Analogon |
| HU208553B (en) * | 1987-07-28 | 1993-11-29 | Gist Brocades Nv | Process for producing polypeptides, plasmides coding them and transformed kluyveromyces |
| ES2204884T3 (es) * | 1988-01-05 | 2004-05-01 | Roche Diagnostics Gmbh | Procedimiento para la obtencion de proteinas o productos genicos que contienen proteinas. |
| EP0336056B1 (de) * | 1988-01-27 | 1995-04-05 | M & D RESEARCH CO., LTD. | Protease |
| FR2645175B1 (fr) * | 1989-03-31 | 1994-02-18 | Transgene Sa | Souche de saccharomyces cerevisiaeproductrice d'une proteine heterologue et procede de preparation de ladite proteine heterologue par fermentation de ladite souche |
| BE1004360A3 (fr) * | 1989-03-31 | 1992-11-10 | Debergh Ludo | Dispositif de fermeture etanche pour regard. |
| AU661844B2 (en) * | 1991-04-01 | 1995-08-10 | Merck Sharp & Dohme Corp. | Genes which influence (pichia) proteolytic activity, and uses therefor |
-
1992
- 1992-06-25 FR FR9207785A patent/FR2692907B1/fr not_active Expired - Fee Related
-
1993
- 1993-06-23 WO PCT/FR1993/000623 patent/WO1994000579A1/fr active IP Right Grant
- 1993-06-23 DE DE69334143T patent/DE69334143T2/de not_active Expired - Lifetime
- 1993-06-23 JP JP6502100A patent/JPH07508166A/ja active Pending
- 1993-06-23 AT AT93913176T patent/ATE363539T1/de active
- 1993-06-23 US US09/640,305 patent/USRE37447E1/en not_active Expired - Lifetime
- 1993-06-23 AU AU43337/93A patent/AU4333793A/en not_active Abandoned
- 1993-06-23 ES ES93913176T patent/ES2287928T3/es not_active Expired - Lifetime
- 1993-06-23 PT PT93913176T patent/PT672150E/pt unknown
- 1993-06-23 DK DK93913176T patent/DK0672150T3/da active
- 1993-06-23 US US08/360,673 patent/US5679544A/en not_active Ceased
- 1993-06-23 EP EP93913176A patent/EP0672150B1/de not_active Expired - Lifetime
- 1993-06-23 CA CA002139117A patent/CA2139117A1/fr not_active Abandoned
-
1994
- 1994-12-23 FI FI946076A patent/FI120589B/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US5679544A (en) | 1997-10-21 |
| JPH07508166A (ja) | 1995-09-14 |
| CA2139117A1 (fr) | 1994-01-06 |
| DE69334143D1 (de) | 2007-07-12 |
| AU4333793A (en) | 1994-01-24 |
| PT672150E (pt) | 2007-09-07 |
| ATE363539T1 (de) | 2007-06-15 |
| FR2692907A1 (fr) | 1993-12-31 |
| USRE37447E1 (en) | 2001-11-13 |
| EP0672150B1 (de) | 2007-05-30 |
| DE69334143T2 (de) | 2008-01-31 |
| EP0672150A1 (de) | 1995-09-20 |
| ES2287928T3 (es) | 2007-12-16 |
| FI946076A (fi) | 1994-12-23 |
| FR2692907B1 (fr) | 1995-06-30 |
| DK0672150T3 (da) | 2007-10-08 |
| FI946076A0 (fi) | 1994-12-23 |
| WO1994000579A1 (fr) | 1994-01-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer of assignment of patent |
Owner name: AVENTIS PHARMA S.A. |
|
| FG | Patent granted |
Ref document number: 120589 Country of ref document: FI |
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| MA | Patent expired |