FI120147B - Enterokineettinen bentsamidi - Google Patents

Enterokineettinen bentsamidi Download PDF

Info

Publication number
FI120147B
FI120147B FI972203A FI972203A FI120147B FI 120147 B FI120147 B FI 120147B FI 972203 A FI972203 A FI 972203A FI 972203 A FI972203 A FI 972203A FI 120147 B FI120147 B FI 120147B
Authority
FI
Finland
Prior art keywords
compound
formula
preparation
dihydro
chloro
Prior art date
Application number
FI972203A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI972203A (fi
FI972203A0 (fi
Inventor
Daele Georges Henri Paul Van
Jean-Paul Rene Marie A Bosmans
Marie-Louise Hendrickx
Daele Kurt Godfried Cornel Van
Joannes Adrianus Jac Schuurkes
Daele Peter Jules Victor Van
Daele Glenn Kurt Ludo Van
Original Assignee
Movetis N V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8217407&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI120147(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Movetis N V filed Critical Movetis N V
Publication of FI972203A publication Critical patent/FI972203A/fi
Publication of FI972203A0 publication Critical patent/FI972203A0/fi
Application granted granted Critical
Publication of FI120147B publication Critical patent/FI120147B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI972203A 1994-11-24 1997-05-23 Enterokineettinen bentsamidi FI120147B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP94203421 1994-11-24
EP94203421 1994-11-24
EP9504519 1995-11-16
PCT/EP1995/004519 WO1996016060A1 (en) 1994-11-24 1995-11-16 Enterokinetic benzamide

Publications (3)

Publication Number Publication Date
FI972203A FI972203A (fi) 1997-05-23
FI972203A0 FI972203A0 (fi) 1997-05-23
FI120147B true FI120147B (fi) 2009-07-15

Family

ID=8217407

Family Applications (1)

Application Number Title Priority Date Filing Date
FI972203A FI120147B (fi) 1994-11-24 1997-05-23 Enterokineettinen bentsamidi

Country Status (40)

Country Link
US (3) US5854260A (cs)
EP (1) EP0807110B1 (cs)
JP (1) JP3046076B2 (cs)
KR (1) KR100233489B1 (cs)
CN (1) CN1071332C (cs)
AP (1) AP777A (cs)
AR (1) AR001769A1 (cs)
AT (1) ATE217306T1 (cs)
AU (1) AU704043B2 (cs)
BG (1) BG63710B1 (cs)
BR (1) BRPI9509819B8 (cs)
CA (1) CA2205573C (cs)
CY (2) CY2296B1 (cs)
CZ (1) CZ292847B6 (cs)
DE (2) DE69526679T2 (cs)
DK (1) DK0807110T3 (cs)
EE (1) EE03313B1 (cs)
ES (1) ES2177671T3 (cs)
FI (1) FI120147B (cs)
FR (1) FR10C0001I2 (cs)
HR (1) HRP950571B1 (cs)
HU (1) HU226560B1 (cs)
IL (1) IL116101A (cs)
LU (1) LU91644I2 (cs)
MY (1) MY112944A (cs)
NL (1) NL300435I1 (cs)
NO (3) NO312726B1 (cs)
NZ (1) NZ297753A (cs)
OA (1) OA10422A (cs)
PL (1) PL183713B1 (cs)
PT (1) PT807110E (cs)
RO (1) RO116279B1 (cs)
RU (1) RU2154643C2 (cs)
SI (1) SI0807110T1 (cs)
SK (1) SK283499B6 (cs)
TR (1) TR199501483A2 (cs)
TW (1) TW490465B (cs)
UA (1) UA59334C2 (cs)
WO (1) WO1996016060A1 (cs)
ZA (1) ZA959996B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW490465B (en) * 1994-11-24 2002-06-11 Janssen Pharmaceutica Nv Enterokinetic benzamide, the preparation process and the pharmaceutical compositions thereof
TW548103B (en) * 1997-07-11 2003-08-21 Janssen Pharmaceutica Nv Bicyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives
EP1077973A2 (en) * 1998-05-14 2001-02-28 Egis Gyogyszergyar Rt. Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
WO2000030640A1 (en) * 1998-11-23 2000-06-02 Janssen Pharmaceutica N.V. Use of prucalopride for the manufacture of a medicament for the treatment of dyspepsia
TW592709B (en) * 1999-04-29 2004-06-21 Janssen Pharmaceutica Nv Prucalopride oral solution
CN1288730A (zh) * 1999-09-07 2001-03-28 麦克内尔-Ppc股份有限公司 轻泻组合物
PL214274B1 (pl) * 2002-01-16 2013-07-31 Movetis N V N-Tlenek prukaloprydu, sposób jego wytwarzania i zastosowanie oraz zawierająca go kompozycja i sposób jej wytwarzania
CN104958298A (zh) * 2009-09-18 2015-10-07 阿得罗公司 阿片样受体拮抗剂用于胃肠道疾病的用途
GB201103397D0 (cs) 2011-02-28 2011-04-13 Shire Movetis N V
CN102295594B (zh) * 2011-07-12 2016-01-20 上海医药工业研究院 4-n-取代-1-(3-甲氧基丙基)-4-哌啶胺类化合物及制备和应用
CA2845039A1 (en) 2011-08-18 2013-02-21 Shire Ag Combinations of a 5-ht4 receptor agonist and a pde4 inhibitor for use in therapy
WO2017137910A1 (en) * 2016-02-11 2017-08-17 Symed Labs Limited Processes for the preparation of highly pure prucalopride succinate and its intermediates
CN108727351B (zh) * 2017-04-19 2021-08-31 鲁南制药集团股份有限公司 一种普芦卡必利的精制方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374637A (en) * 1989-03-22 1994-12-20 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives
GB9005014D0 (en) * 1990-03-06 1990-05-02 Janssen Pharmaceutica Nv N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives
TW490465B (en) * 1994-11-24 2002-06-11 Janssen Pharmaceutica Nv Enterokinetic benzamide, the preparation process and the pharmaceutical compositions thereof

Also Published As

Publication number Publication date
NO2019044I1 (no) 2019-12-11
NO972143D0 (no) 1997-05-09
BG63710B1 (bg) 2002-10-31
BG101605A (en) 1998-02-27
CZ155597A3 (en) 1997-09-17
SK65297A3 (en) 1997-10-08
CA2205573C (en) 2006-05-09
FI972203A (fi) 1997-05-23
TR199501483A2 (tr) 1996-07-21
TW490465B (en) 2002-06-11
OA10422A (en) 2002-03-19
FR10C0001I1 (cs) 2010-02-12
CZ292847B6 (cs) 2003-12-17
US6310077B1 (en) 2001-10-30
CN1071332C (zh) 2001-09-19
JP3046076B2 (ja) 2000-05-29
NZ297753A (en) 1998-05-27
BRPI9509819B8 (pt) 2021-07-06
NO2010003I1 (no) 2010-03-05
EP0807110A1 (en) 1997-11-19
CA2205573A1 (en) 1996-05-30
MX9703869A (es) 1997-09-30
CN1164233A (zh) 1997-11-05
FI972203A0 (fi) 1997-05-23
HUT77375A (hu) 1998-04-28
DE122010000002I1 (de) 2011-12-01
AP9700992A0 (en) 1997-07-31
DE69526679T2 (de) 2002-12-05
AP777A (en) 1999-10-28
IL116101A (en) 1999-08-17
EP0807110B1 (en) 2002-05-08
ATE217306T1 (de) 2002-05-15
NO972143L (no) 1997-05-09
BRPI9509819B1 (pt) 2018-05-15
EE03313B1 (et) 2000-12-15
AU4299296A (en) 1996-06-17
NO312726B1 (no) 2002-06-24
DE69526679D1 (de) 2002-06-13
NL300435I1 (nl) 2010-04-01
DK0807110T3 (da) 2002-09-02
WO1996016060A1 (en) 1996-05-30
PL320297A1 (en) 1997-09-15
HRP950571B1 (en) 2001-12-31
US5948794A (en) 1999-09-07
CY2010001I2 (el) 2010-07-28
US5854260A (en) 1998-12-29
BR9509819A (pt) 1997-09-30
RO116279B1 (ro) 2000-12-29
AU704043B2 (en) 1999-04-15
RU2154643C2 (ru) 2000-08-20
LU91644I2 (en) 2010-03-29
CY2010001I1 (el) 2010-07-28
HU226560B1 (en) 2009-04-28
KR100233489B1 (ko) 1999-12-01
SI0807110T1 (en) 2002-08-31
ES2177671T3 (es) 2002-12-16
FR10C0001I2 (fr) 2011-04-01
HRP950571A2 (en) 1997-08-31
NO2010003I2 (no) 2012-08-27
UA59334C2 (uk) 2003-09-15
ZA959996B (en) 1997-05-23
CY2296B1 (en) 2003-07-04
MY112944A (en) 2001-10-31
PL183713B1 (pl) 2002-07-31
PT807110E (pt) 2002-10-31
SK283499B6 (sk) 2003-08-05
AR001769A1 (es) 1997-12-10
JPH09512832A (ja) 1997-12-22
IL116101A0 (en) 1996-01-31

Similar Documents

Publication Publication Date Title
FI120147B (fi) Enterokineettinen bentsamidi
CA2498275C (en) Hydroxy alkyl substituted 1,3,8-triazaspiro[4.5]decan-4-one derivatives useful for the treatment of orl-1 receptor mediated disorders
RU2413721C2 (ru) Замещенные имидазолы, фармацевтическая композиция, способ лечения заболевания, связанного по крайней мере с активностью ksp, и способ ингибирования ksp
US6774241B2 (en) 1-sulfonyl-4-aminoalkoxy indole derivatives and uses thereof
WO2016039408A1 (ja) 複素環化合物
JP2502343B2 (ja) 薬学的に活性な置換ベンズアミド
JP2024516633A (ja) オレキシン-2受容体アゴニスト活性を有する置換されるアミド大環状化合物
EP1611126B1 (de) Chromenonindole
JP2012503000A (ja) Orl−1受容体調節因子として有用な5−オキサゾリジン−2−オン置換1,3,8−トリアザスピロ[4.5]デカン−4−オン誘導体
EP1888577B1 (en) Ocaperidone salts and pharmaceutical compositions containing the same
MXPA97003869A (en) Benzamida enterocinet
JPH06179685A (ja) ピロロチアゾールカルボキサミド誘導体

Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: MOVETIS N.V.

Free format text: MOVETIS N.V.

FG Patent granted

Ref document number: 120147

Country of ref document: FI

SPCF Supplementary protection certificate application filed

Free format text: SPC C20100004

PC Transfer of assignment of patent

Owner name: SHIRE-MOVETIS N.V

Free format text: SHIRE-MOVETIS N.V

SPCG Supplementary protection certificate granted

Spc suppl protection certif: 370

Extension date: 20201116

MA Patent expired
SPCP Extension of a supplementary protection certificate [pediatric extension]

Spc suppl protection certif: 370

Extension date: 20210516