FI118601B - Menetelmä terapeuttisesti käyttökelpoisen amyliiniagonistianalogin tai sen suolan valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisen amyliiniagonistianalogin tai sen suolan valmistamiseksi Download PDF

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Publication number
FI118601B
FI118601B FI933252A FI933252A FI118601B FI 118601 B FI118601 B FI 118601B FI 933252 A FI933252 A FI 933252A FI 933252 A FI933252 A FI 933252A FI 118601 B FI118601 B FI 118601B
Authority
FI
Finland
Prior art keywords
amylin
analog
prepared
amylinagonist
pro
Prior art date
Application number
FI933252A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI933252A0 (fi
FI933252A (fi
Inventor
Howard Jones
Laura S L Gaeta
Elisabeth Albrecht
Original Assignee
Amylin Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amylin Pharmaceuticals Inc filed Critical Amylin Pharmaceuticals Inc
Publication of FI933252A0 publication Critical patent/FI933252A0/fi
Publication of FI933252A publication Critical patent/FI933252A/fi
Application granted granted Critical
Publication of FI118601B publication Critical patent/FI118601B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI933252A 1991-11-19 1993-07-16 Menetelmä terapeuttisesti käyttökelpoisen amyliiniagonistianalogin tai sen suolan valmistamiseksi FI118601B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US79426691A 1991-11-19 1991-11-19
US79426691 1991-11-19
PCT/US1992/009842 WO1993010146A1 (fr) 1991-11-19 1992-11-19 Peptides a action agoniste a base d'amyline et utilisations de ces peptides
US9209842 1992-11-19

Publications (3)

Publication Number Publication Date
FI933252A0 FI933252A0 (fi) 1993-07-16
FI933252A FI933252A (fi) 1993-08-23
FI118601B true FI118601B (fi) 2008-01-15

Family

ID=25162163

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933252A FI118601B (fi) 1991-11-19 1993-07-16 Menetelmä terapeuttisesti käyttökelpoisen amyliiniagonistianalogin tai sen suolan valmistamiseksi

Country Status (17)

Country Link
EP (2) EP1162207A1 (fr)
JP (4) JP2902115B2 (fr)
AT (1) ATE205854T1 (fr)
AU (1) AU714439B2 (fr)
CA (1) CA2100745C (fr)
CZ (1) CZ288029B6 (fr)
DE (1) DE69232064T2 (fr)
DK (1) DK0567626T3 (fr)
ES (1) ES2161697T3 (fr)
FI (1) FI118601B (fr)
GR (1) GR3036794T3 (fr)
HK (1) HK1041891A1 (fr)
MD (1) MD960317A (fr)
NO (2) NO324405B1 (fr)
RU (1) RU2130463C1 (fr)
SK (1) SK88793A3 (fr)
WO (1) WO1993010146A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU222249B1 (hu) 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
US5625032A (en) * 1993-07-21 1997-04-29 Amylin Pharmaceuticals, Inc. Selective amylin antagonist peptides and uses therefor
CN1134110A (zh) 1993-09-07 1996-10-23 安米林药品公司 调节胃肠动力的方法
US6143718A (en) * 1995-06-07 2000-11-07 Amylin Pharmaceuticals, Inc. Treatment of Type II diabetes mellutis with amylin agonists
US5739106A (en) * 1995-06-07 1998-04-14 Rink; Timothy J. Appetite regulating compositions
US7312196B2 (en) 1997-01-08 2007-12-25 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
US6410511B2 (en) 1997-01-08 2002-06-25 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
US7101853B2 (en) * 1997-05-06 2006-09-05 Amylin Pharmaceuticals, Inc. Method for treating or preventing gastritis using amylin or amylin agonists
US7910548B2 (en) 1997-06-06 2011-03-22 Amylin Pharmaceuticals, Inc. Methods for treating obesity
JP4353544B2 (ja) * 1998-01-09 2009-10-28 アミリン・ファーマシューティカルズ，インコーポレイテッド アミリン作動薬ペプチド用製剤
GB0128583D0 (en) 2001-11-28 2002-01-23 Rsr Ltd Detection of autoantibodies indicative of diabetes
AU2003278929A1 (en) 2002-10-18 2004-05-13 Amylin Pharmaceuticals, Inc. Treatment of pancreatitis with amylin
WO2004083243A1 (fr) * 2003-03-18 2004-09-30 Applied Research Systems Ars Holding N.V. Inhibiteurs d'agregation d'amyline et utilisation desdits inhibiteurs.
BRPI0518390A2 (pt) * 2004-10-26 2008-11-18 Lonza Ag mÉtodo de sÍntese de peptÍdeo, e respectivo peptÍdeo
US8394765B2 (en) 2004-11-01 2013-03-12 Amylin Pharmaceuticals Llc Methods of treating obesity with two different anti-obesity agents
ATE427759T1 (de) 2004-11-01 2009-04-15 Amylin Pharmaceuticals Inc Behandlung von fettsucht und verbundenen erkrankungen
KR101383493B1 (ko) 2005-03-31 2014-04-11 아스트라제네카 파마수티컬스 엘피 정신의학적 질환 및 장애를 치료하기 위한 아밀린 및아밀린 효능제
US8168592B2 (en) 2005-10-21 2012-05-01 Amgen Inc. CGRP peptide antagonists and conjugates
NZ574710A (en) 2006-09-07 2012-02-24 Nycomed Gmbh Combination treatment comprising the PDE4 inhibitor Compound A ((2R,4aR, 10bR)6-(2,6-Dimethoxy-pyridin-3-yl)-9-ethoxy-8-methoxy-1 ,2,3,4,4a,10b-hexahydrophenanthridin-2-ol) for diabetes mellitus
EP2120985B1 (fr) 2007-02-05 2012-06-27 Amylin Pharmaceuticals, Inc. FN-38 peptides pour son utilisation dans le traitement des maladies psychotiques et des troubles anxieux
JP2009149684A (ja) * 2009-03-11 2009-07-09 Amylin Pharmaceut Inc アミリン作動薬ペプチド用製剤
EP2405934B1 (fr) 2009-03-12 2014-03-26 Nordic Bioscience A/S Traitement du diabète et du syndrome métabolique
AR097701A1 (es) * 2013-09-19 2016-04-13 Zealand Pharma As Análogos de amilina
KR20160094956A (ko) 2013-11-05 2016-08-10 벤-구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨럽먼트 어쏘러티 당뇨병 및 당뇨병으로부터 발생하는 합병증 질환의 치료를 위한 화합물
US10072060B2 (en) 2014-05-02 2018-09-11 The Research Foundation For The State University Of New York Islet amyloid polypeptides with improved solubility
EP3271381B1 (fr) 2015-03-18 2021-09-08 Zealand Pharma A/S Analogues d'amyline
US10071140B2 (en) 2016-09-09 2018-09-11 Zealand Pharma A/S Amylin analogues
WO2018144671A1 (fr) 2017-02-01 2018-08-09 The Research Foundation For The State University Of New York Polypeptides à îlots amyloïdes mutants présentant une solubilité améliorée et leurs procédés d'utilisation
KR102130354B1 (ko) * 2019-08-14 2020-07-06 엘아이지넥스원 주식회사 코어 제거용 이형장치
US20240335513A1 (en) 2022-05-30 2024-10-10 Zealand Pharma A/S Liquid formulations of amylin analogues
WO2024061919A1 (fr) 2022-09-19 2024-03-28 Zealand Pharma A/S Polythérapie

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8720115D0 (en) * 1987-08-26 1987-09-30 Cooper G J S Treatment of diabetes mellitus
AU631112B2 (en) * 1988-01-11 1992-11-19 Amylin Corporation Treatment of type 2 diabetes mellitus
ATE128032T1 (de) * 1989-07-10 1995-10-15 Amylin Pharmaceuticals Inc Verwendung eines amylinantagonisten zur herstellung eines artzneimittels zur behandlung von fettsucht und essentieller hypertonie und damit zusammenhängenden krankheiten.
US5234906A (en) * 1991-01-10 1993-08-10 Amylin Pharmaceuticals, Inc. Hyperglycemic compositions
WO1992015317A1 (fr) * 1991-03-08 1992-09-17 Amylin Pharmaceuticals, Inc. Preparation synthetique d'amyline et d'analogues d'amyline

Also Published As

Publication number Publication date
FI933252A0 (fi) 1993-07-16
AU3075392A (en) 1993-06-15
AU1245697A (en) 1997-03-27
NO932603L (no) 1993-09-17
ES2161697T3 (es) 2001-12-16
EP0567626B1 (fr) 2001-09-19
FI933252A (fi) 1993-08-23
SK88793A3 (en) 1994-12-07
NO932603D0 (no) 1993-07-19
HK1041891A1 (zh) 2002-07-26
JP2902115B2 (ja) 1999-06-07
CA2100745C (fr) 2007-07-31
EP1162207A1 (fr) 2001-12-12
WO1993010146A1 (fr) 1993-05-27
GR3036794T3 (en) 2002-01-31
AU714439B2 (en) 2000-01-06
RU2130463C1 (ru) 1999-05-20
AU673147B2 (en) 1996-10-31
CA2100745A1 (fr) 1993-05-20
MD960317A (ro) 1998-05-31
JP2006213716A (ja) 2006-08-17
ATE205854T1 (de) 2001-10-15
NO324405B1 (no) 2007-10-08
DE69232064D1 (de) 2001-10-25
DK0567626T3 (da) 2001-12-17
EP0567626A1 (fr) 1993-11-03
JP2003238594A (ja) 2003-08-27
CZ288029B6 (cs) 2001-04-11
JP4018116B2 (ja) 2007-12-05
CZ168993A3 (en) 1994-04-13
NO20073265L (no) 1993-09-17
DE69232064T2 (de) 2002-03-28
JPH11152299A (ja) 1999-06-08
JPH06504794A (ja) 1994-06-02

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