FI114826B - Sidontamääritys, jossa käytetään häntäryhmiä sisältäviä sidonta-aineita - Google Patents

Sidontamääritys, jossa käytetään häntäryhmiä sisältäviä sidonta-aineita Download PDF

Info

Publication number
FI114826B
FI114826B FI963560A FI963560A FI114826B FI 114826 B FI114826 B FI 114826B FI 963560 A FI963560 A FI 963560A FI 963560 A FI963560 A FI 963560A FI 114826 B FI114826 B FI 114826B
Authority
FI
Finland
Prior art keywords
att
som
analyte
binding
vid
Prior art date
Application number
FI963560A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI963560A0 (fi
FI963560A (fi
Inventor
Roger Philip Ekins
Original Assignee
Multilyte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Multilyte Ltd filed Critical Multilyte Ltd
Publication of FI963560A0 publication Critical patent/FI963560A0/fi
Publication of FI963560A publication Critical patent/FI963560A/fi
Application granted granted Critical
Publication of FI114826B publication Critical patent/FI114826B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/10—Oligonucleotides as tagging agents for labelling antibodies
FI963560A 1994-03-11 1996-09-10 Sidontamääritys, jossa käytetään häntäryhmiä sisältäviä sidonta-aineita FI114826B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9500521 1994-03-10
GB9404709 1994-03-11
GB9404709A GB9404709D0 (en) 1994-03-11 1994-03-11 Binding assay
PCT/GB1995/000521 WO1995024649A1 (en) 1994-03-11 1995-03-10 Binding assay using binding agents with tail groups

Publications (3)

Publication Number Publication Date
FI963560A0 FI963560A0 (fi) 1996-09-10
FI963560A FI963560A (fi) 1996-09-10
FI114826B true FI114826B (fi) 2004-12-31

Family

ID=10751658

Family Applications (1)

Application Number Title Priority Date Filing Date
FI963560A FI114826B (fi) 1994-03-11 1996-09-10 Sidontamääritys, jossa käytetään häntäryhmiä sisältäviä sidonta-aineita

Country Status (10)

Country Link
US (3) US6316186B1 (ja)
EP (1) EP0749581B1 (ja)
JP (2) JP3431160B2 (ja)
AU (1) AU1857195A (ja)
DE (1) DE69506387T2 (ja)
ES (1) ES2127514T3 (ja)
FI (1) FI114826B (ja)
GB (1) GB9404709D0 (ja)
HK (1) HK1014044A1 (ja)
WO (1) WO1995024649A1 (ja)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9404709D0 (en) * 1994-03-11 1994-04-27 Multilyte Ltd Binding assay
ES2288760T3 (es) 1996-04-25 2008-01-16 Bioarray Solutions Ltd. Ensamblaje electrocinetico controlado por luz de particulas proximas a superficies.
SE9604575D0 (sv) 1996-12-12 1996-12-12 Biacore Ab Method and system for analyte determination
CA2285918C (en) * 1997-04-04 2007-07-03 Biosite Diagnostics Methods for concentrating ligands using magnetic particles
DE19741716A1 (de) * 1997-09-22 1999-03-25 Hoechst Ag Adressierbares modulares Erkennungssystem, seine Herstellung und Verwendung
US7157234B2 (en) 1997-10-24 2007-01-02 Beckman Coulter, Inc. Detection of very low quantities of analyte bound to a solid phase
AUPP103497A0 (en) * 1997-12-19 1998-01-15 Panbio Pty Ltd Assay apparatus
EP2189791A3 (en) 1998-02-04 2011-03-09 Life Technologies Corporation Microarrays and uses therefor
US20010031468A1 (en) * 2000-02-08 2001-10-18 Alex Chenchik Analyte assays employing universal arrays
WO2001083827A1 (en) 2000-05-04 2001-11-08 Yale University High density protein arrays for screening of protein activity
DE60117556T2 (de) 2000-06-21 2006-11-02 Bioarray Solutions Ltd. Multianalytische molekularanalyse durch verwendung anwendungsspezifischer zufallspartikelarrays
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
AU3237902A (en) 2000-10-12 2002-04-29 New York Health Res Inst Oligonucleotide - facilitated coalescence
US20030082571A1 (en) * 2001-04-10 2003-05-01 Kachab Edward Hanna Linear nucleic acid and sequence therefor
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US20040161741A1 (en) 2001-06-30 2004-08-19 Elazar Rabani Novel compositions and processes for analyte detection, quantification and amplification
US9777312B2 (en) 2001-06-30 2017-10-03 Enzo Life Sciences, Inc. Dual polarity analysis of nucleic acids
US9261460B2 (en) 2002-03-12 2016-02-16 Enzo Life Sciences, Inc. Real-time nucleic acid detection processes and compositions
ES2661167T3 (es) 2001-10-15 2018-03-27 Bioarray Solutions Ltd. Análisis multiplexado de loci polimórficos mediante consulta simultánea y detección mediada por enzimas
US9353405B2 (en) 2002-03-12 2016-05-31 Enzo Life Sciences, Inc. Optimized real time nucleic acid detection processes
US7041453B2 (en) * 2002-08-22 2006-05-09 Bioarray Solutions Ltd. Molecular constructs and methods of use for detection of biochemical reactions
US7526114B2 (en) 2002-11-15 2009-04-28 Bioarray Solutions Ltd. Analysis, secure access to, and transmission of array images
US7229763B2 (en) * 2003-04-07 2007-06-12 Beckman Coulter, Inc. Assay system using labeled oligonucleotides
US20040229226A1 (en) * 2003-05-16 2004-11-18 Reddy M. Parameswara Reducing microarray variation with internal reference spots
WO2005029705A2 (en) 2003-09-18 2005-03-31 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
AU2004276761B2 (en) 2003-09-22 2009-12-24 Bioarray Solutions, Ltd. Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
AU2004286252A1 (en) 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
AU2004287069B2 (en) 2003-10-29 2009-07-16 Bioarray Solutions, Ltd. Multiplexed nucleic acid analysis by fragmentation of double-stranded DNA
EP1722228A1 (en) * 2004-03-05 2006-11-15 Nisshinbo Industries, Inc. Immobilized biomolecule and method of detecting substance capable of interacting with biomolecule
WO2005090972A1 (ja) * 2004-03-18 2005-09-29 Nissui Pharmaceutical Co., Ltd. 生物学的物質の分析キット、分析装置及び分析方法
US7364898B2 (en) * 2004-05-04 2008-04-29 Eppendorf Ag Customized micro-array construction and its use for target molecule detection
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
GB0421838D0 (en) 2004-09-30 2004-11-03 Congenia S R L Cancer markers
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
JP4243319B2 (ja) * 2006-04-28 2009-03-25 凸版印刷株式会社 蛋白質チップ
JP2009545747A (ja) * 2006-08-02 2009-12-24 カリフォルニア インスティチュート オブ テクノロジー 標的を検出及び／又は選別する方法並びにシステム
US20090032446A1 (en) * 2007-08-01 2009-02-05 Triwatech, L.L.C. Mobile station and methods for diagnosing and modeling site specific effluent treatment facility requirements
SE533515C2 (sv) 2008-04-16 2010-10-12 Aamic Ab Analysförfarande för samtidig analys av flera analyter
US8309306B2 (en) * 2008-11-12 2012-11-13 Nodality, Inc. Detection composition
EP2389585A2 (en) * 2009-01-22 2011-11-30 Li-Cor, Inc. Single molecule proteomics with dynamic probes
GB201016403D0 (en) 2010-09-29 2010-11-10 Bath Ventures Novel interaction between staphylococcus aureus Sbi and C3d protiens
GB201021909D0 (en) 2010-12-23 2011-02-02 Randox Lab Ltd Multi-analyte microarrays using tag-specific antibodies and tag-anchored antibodies
JP2021510085A (ja) * 2018-01-05 2021-04-15 クオシェント スイッス エスエー 自己組織型診断アレイプラットフォーム
WO2019243391A1 (en) 2018-06-21 2019-12-26 F. Hoffmann-La Roche Ag Hybridizing all-lna oligonucleotides
WO2020099533A1 (en) 2018-11-16 2020-05-22 F. Hoffmann-La Roche Ag Streptavidin-coated solid phases with a member of a binding pair
BR112021024624A2 (pt) 2019-06-07 2022-01-18 Hoffmann La Roche Métodos para selecionar e fornecer um par de ligação de oligonucleotídeos de fita simples, para formar um duplex antiparalelo e para realizar um ensaio, par de ss-oligonucleotídeos complementares separados, duplex antiparalelo, uso de um par de ss-oligonucleotídeos separados, kit para realizar um ensaio e composição líquida

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1944283A (en) 1982-08-27 1984-03-29 Ekins Roger Philip Measurement of analyte concentration
US4748111A (en) * 1984-03-12 1988-05-31 Molecular Diagnostics, Inc. Nucleic acid-protein conjugate used in immunoassay
US5175270A (en) * 1986-09-10 1992-12-29 Polyprobe, Inc. Reagents for detecting and assaying nucleic acid sequences
WO1990012115A1 (en) * 1989-03-21 1990-10-18 Collaborative Research, Inc. A dna diagnostic test using an exonuclease activity
US5120662A (en) 1989-05-09 1992-06-09 Abbott Laboratories Multilayer solid phase immunoassay support and method of use
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
ATE193019T1 (de) * 1989-10-13 2000-06-15 Zeneca Ltd Sonden
US5252743A (en) * 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
JPH04273065A (ja) 1991-02-28 1992-09-29 Hitachi Ltd 免疫分析方法およびその分析装置
US5646001A (en) * 1991-03-25 1997-07-08 Immunivest Corporation Affinity-binding separation and release of one or more selected subset of biological entities from a mixed population thereof
DE69432897T2 (de) * 1993-05-10 2004-05-27 Nissui Pharmaceutical Co., Ltd. Verfahren zur bestimmung von mehr als einem immunologischen liganden und bestimmungsreagenz sowie satz dafuer
GB9404709D0 (en) * 1994-03-11 1994-04-27 Multilyte Ltd Binding assay
US5648213A (en) * 1994-08-30 1997-07-15 Beckman Instruments, Inc. Compositions and methods for use in detection of analytes
US6287778B1 (en) * 1999-10-19 2001-09-11 Affymetrix, Inc. Allele detection using primer extension with sequence-coded identity tags

Also Published As

Publication number Publication date
FI963560A0 (fi) 1996-09-10
EP0749581A1 (en) 1996-12-27
US7588893B2 (en) 2009-09-15
US6316186B1 (en) 2001-11-13
US20020182617A1 (en) 2002-12-05
ES2127514T3 (es) 1999-04-16
WO1995024649A1 (en) 1995-09-14
US20060204983A1 (en) 2006-09-14
JP2003156493A (ja) 2003-05-30
HK1014044A1 (en) 1999-09-17
FI963560A (fi) 1996-09-10
JP3619222B2 (ja) 2005-02-09
JPH10512664A (ja) 1998-12-02
DE69506387T2 (de) 1999-05-12
JP3431160B2 (ja) 2003-07-28
AU1857195A (en) 1995-09-25
EP0749581B1 (en) 1998-12-02
DE69506387D1 (de) 1999-01-14
GB9404709D0 (en) 1994-04-27

Similar Documents

Publication Publication Date Title
FI114826B (fi) Sidontamääritys, jossa käytetään häntäryhmiä sisältäviä sidonta-aineita
US5332659A (en) Light emission-or absorbance-based binding assays for polynucleic acids
Diamandis et al. Europium chelate labels in time-resolved fluorescence immunoassays and DNA hybridization assays
US6743640B2 (en) Fluorescent polymer-QTL approach to biosensing
JP3021038B2 (ja) 標識技術を用いた複数分析物の検出または定量
US20130210003A1 (en) Compositions for use in detection of multiple analytes
CN101545007A (zh) 一种纳米金生物复合探针、检测方法及其应用
WO1999042838A1 (en) Chemiluminescent compositions for use in detection of multiple analytes
KR20060052676A (ko) 크로마토그래피 측정 시스템
CN103608675B (zh) 发光聚合物循环扩增
JPH06505802A (ja) 遊離自在リガンドを用いた特異的結合アッセイ方法
US4921788A (en) Competitive nucleic acid immunoassay for the detection of analytes
JP2007519933A (ja) 動的表面生成及び画像化を使用する、生物学的及び化学的物質の検出のためのシステム、方法、及び試薬
Qin et al. A sensitive gold nanoparticles sensing platform based on resonance energy transfer for chemiluminescence light on detection of biomolecules
US5672475A (en) Mixed luminescent conjugate test
CN106568967A (zh) 一种针对赭曲霉毒素a的灵敏检测方法
CN107923908A (zh) 具有提高的灵敏度的免疫检定
CN108663513A (zh) 一种降低侧流层析试纸检测限的方法
CN101490536A (zh) 非分离式测定方法
US5314802A (en) Light emission- or absorbance-based binding assays
CN1201150C (zh) 一种组合物,化学发光体系及其应用
Bruno et al. Novel immuno-FRET assay method for Bacillus spores and Escherichia coli O157: H7
Kamyshny et al. Fluorescence immunoassay based on fluorescer microparticles
Kamyshny et al. Chemiluminescence immunoassay in microemulsions
US20050148005A1 (en) Dye solubilization binding assay

Legal Events

Date Code Title Description
MA Patent expired