FI111644B - Menetelmä terapeuttisesti käyttökelpoisten monokvaternaaristen 2,16-bispiperidinyyliandrostaanijohdannaisten valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten monokvaternaaristen 2,16-bispiperidinyyliandrostaanijohdannaisten valmistamiseksi Download PDF

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Publication number
FI111644B
FI111644B FI931794A FI931794A FI111644B FI 111644 B FI111644 B FI 111644B FI 931794 A FI931794 A FI 931794A FI 931794 A FI931794 A FI 931794A FI 111644 B FI111644 B FI 111644B
Authority
FI
Finland
Prior art keywords
pharmaceutically acceptable
formula
compounds
acid
compound
Prior art date
Application number
FI931794A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI931794A0 (fi
FI931794A (fi
Inventor
Thomas Sleigh
Ian Craig Carlyle
Alan William Muir
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI931794A0 publication Critical patent/FI931794A0/fi
Publication of FI931794A publication Critical patent/FI931794A/fi
Application granted granted Critical
Publication of FI111644B publication Critical patent/FI111644B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Fats And Perfumes (AREA)
FI931794A 1992-04-22 1993-04-21 Menetelmä terapeuttisesti käyttökelpoisten monokvaternaaristen 2,16-bispiperidinyyliandrostaanijohdannaisten valmistamiseksi FI111644B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92303612 1992-04-22
EP92303612 1992-04-22

Publications (3)

Publication Number Publication Date
FI931794A0 FI931794A0 (fi) 1993-04-21
FI931794A FI931794A (fi) 1993-10-23
FI111644B true FI111644B (fi) 2003-08-29

Family

ID=8211340

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931794A FI111644B (fi) 1992-04-22 1993-04-21 Menetelmä terapeuttisesti käyttökelpoisten monokvaternaaristen 2,16-bispiperidinyyliandrostaanijohdannaisten valmistamiseksi

Country Status (17)

Country Link
US (1) US5418226A (ko)
EP (1) EP0571012B1 (ko)
JP (1) JP3344764B2 (ko)
KR (1) KR100281296B1 (ko)
AT (1) ATE145918T1 (ko)
AU (1) AU662277B2 (ko)
CA (1) CA2094457C (ko)
CZ (1) CZ286728B6 (ko)
DE (1) DE69306303T2 (ko)
DK (1) DK0571012T3 (ko)
ES (1) ES2097435T3 (ko)
FI (1) FI111644B (ko)
GR (1) GR3022316T3 (ko)
HK (1) HK1001061A1 (ko)
HU (2) HUT64970A (ko)
MX (1) MX9302303A (ko)
NO (1) NO301931B1 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9302455D0 (en) * 1993-02-08 1993-03-24 Lab Inpharm N V Process for preparing a pharmaceutical preparation having neuromuscular blocking activity
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura
WO1999027914A1 (en) * 1997-11-27 1999-06-10 Akzo Nobel N.V. A pharmaceutical formulation of monoquaternary 2,16-bispiperidinylandrostane for intramuscular administration
HU0402017D0 (en) * 2004-10-07 2004-12-28 Richter Gedeon Vegyeszet Environment-friend process for the synthesis of quaternary ammonio-steroids
MX366310B (es) * 2013-07-01 2019-07-04 Maruishi Pharma Preparacion de rocuronio que causa menos dolor, metodo para producirla, y metodo para reducir y/o aliviar dolor vascular a ser inducido utilizando la misma.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
DE2962627D1 (en) * 1978-09-05 1982-06-09 Akzo Nv Acid addition salts of 16-beta-monoquaternary ammonium derivatives of 2-beta, 16-beta-bis-piperidino-androstanes and pharmaceutical preparations containing same
IE50675B1 (en) * 1979-12-12 1986-06-11 Akzo Nv Bis-and mono-quaternary ammonium derivatives of 2beta,16beta-dipiperidino-5alpha-androstanes,processes for their preparation and pharmaceutical preparations
US4337386A (en) * 1980-01-21 1982-06-29 Caterpillar Tractor Co. Welder control

Also Published As

Publication number Publication date
JPH07267984A (ja) 1995-10-17
KR100281296B1 (ko) 2001-03-02
AU662277B2 (en) 1995-08-24
KR930021653A (ko) 1993-11-22
HU9301173D0 (en) 1993-07-28
NO931466D0 (no) 1993-04-21
ES2097435T3 (es) 1997-04-01
CA2094457C (en) 2003-12-09
JP3344764B2 (ja) 2002-11-18
CZ68093A3 (en) 1994-01-19
EP0571012A3 (en) 1995-04-12
FI931794A0 (fi) 1993-04-21
GR3022316T3 (en) 1997-04-30
NO931466L (no) 1993-10-25
CA2094457A1 (en) 1993-10-23
NO301931B1 (no) 1997-12-29
DK0571012T3 (da) 1997-05-12
EP0571012A2 (en) 1993-11-24
HU211859A9 (en) 1995-12-28
MX9302303A (es) 1994-03-31
FI931794A (fi) 1993-10-23
AU3703093A (en) 1993-10-28
HUT64970A (en) 1994-03-28
DE69306303D1 (de) 1997-01-16
US5418226A (en) 1995-05-23
HK1001061A1 (en) 1998-05-22
ATE145918T1 (de) 1996-12-15
CZ286728B6 (en) 2000-06-14
EP0571012B1 (en) 1996-12-04
DE69306303T2 (de) 1997-04-17

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