HK1001061A1 - Monoquaternary 2,16-bispiperidinylandrostane derivatives - Google Patents

Monoquaternary 2,16-bispiperidinylandrostane derivatives

Info

Publication number
HK1001061A1
HK1001061A1 HK97102514A HK97102514A HK1001061A1 HK 1001061 A1 HK1001061 A1 HK 1001061A1 HK 97102514 A HK97102514 A HK 97102514A HK 97102514 A HK97102514 A HK 97102514A HK 1001061 A1 HK1001061 A1 HK 1001061A1
Authority
HK
Hong Kong
Prior art keywords
bispiperidinylandrostane
monoquaternary
derivatives
pharmaceutically acceptable
allyl
Prior art date
Application number
HK97102514A
Other languages
English (en)
Inventor
Thomas Sleigh
Ian Craig Carlyle
Alan William Muir
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of HK1001061A1 publication Critical patent/HK1001061A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Fats And Perfumes (AREA)
HK97102514A 1992-04-22 1997-12-19 Monoquaternary 2,16-bispiperidinylandrostane derivatives HK1001061A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92303612 1992-04-22

Publications (1)

Publication Number Publication Date
HK1001061A1 true HK1001061A1 (en) 1998-05-22

Family

ID=8211340

Family Applications (1)

Application Number Title Priority Date Filing Date
HK97102514A HK1001061A1 (en) 1992-04-22 1997-12-19 Monoquaternary 2,16-bispiperidinylandrostane derivatives

Country Status (17)

Country Link
US (1) US5418226A (xx)
EP (1) EP0571012B1 (xx)
JP (1) JP3344764B2 (xx)
KR (1) KR100281296B1 (xx)
AT (1) ATE145918T1 (xx)
AU (1) AU662277B2 (xx)
CA (1) CA2094457C (xx)
CZ (1) CZ286728B6 (xx)
DE (1) DE69306303T2 (xx)
DK (1) DK0571012T3 (xx)
ES (1) ES2097435T3 (xx)
FI (1) FI111644B (xx)
GR (1) GR3022316T3 (xx)
HK (1) HK1001061A1 (xx)
HU (2) HUT64970A (xx)
MX (1) MX9302303A (xx)
NO (1) NO301931B1 (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9302455D0 (en) * 1993-02-08 1993-03-24 Lab Inpharm N V Process for preparing a pharmaceutical preparation having neuromuscular blocking activity
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura
AU1874499A (en) * 1997-11-27 1999-06-16 Akzo Nobel N.V. A pharmaceutical formulation of monoquaternary 2,16-bispiperidinylandrostane forintramuscular administration
HU0402017D0 (en) * 2004-10-07 2004-12-28 Richter Gedeon Vegyeszet Environment-friend process for the synthesis of quaternary ammonio-steroids
BR112015030877B1 (pt) * 2013-07-01 2020-10-06 Maruishi Pharmaceutical Co., Ltd Preparação de rocurônio, método para produzir a mesma, e uso de rocurônio

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
DE2962627D1 (en) * 1978-09-05 1982-06-09 Akzo Nv Acid addition salts of 16-beta-monoquaternary ammonium derivatives of 2-beta, 16-beta-bis-piperidino-androstanes and pharmaceutical preparations containing same
IE50675B1 (en) * 1979-12-12 1986-06-11 Akzo Nv Bis-and mono-quaternary ammonium derivatives of 2beta,16beta-dipiperidino-5alpha-androstanes,processes for their preparation and pharmaceutical preparations
US4337386A (en) * 1980-01-21 1982-06-29 Caterpillar Tractor Co. Welder control

Also Published As

Publication number Publication date
US5418226A (en) 1995-05-23
ES2097435T3 (es) 1997-04-01
FI931794A (fi) 1993-10-23
KR930021653A (ko) 1993-11-22
HUT64970A (en) 1994-03-28
DK0571012T3 (da) 1997-05-12
FI111644B (fi) 2003-08-29
HU211859A9 (en) 1995-12-28
MX9302303A (es) 1994-03-31
DE69306303D1 (de) 1997-01-16
JP3344764B2 (ja) 2002-11-18
AU662277B2 (en) 1995-08-24
EP0571012B1 (en) 1996-12-04
CA2094457A1 (en) 1993-10-23
DE69306303T2 (de) 1997-04-17
CA2094457C (en) 2003-12-09
KR100281296B1 (ko) 2001-03-02
CZ68093A3 (en) 1994-01-19
HU9301173D0 (en) 1993-07-28
NO301931B1 (no) 1997-12-29
AU3703093A (en) 1993-10-28
NO931466D0 (no) 1993-04-21
FI931794A0 (fi) 1993-04-21
EP0571012A3 (en) 1995-04-12
NO931466L (no) 1993-10-25
GR3022316T3 (en) 1997-04-30
EP0571012A2 (en) 1993-11-24
CZ286728B6 (en) 2000-06-14
JPH07267984A (ja) 1995-10-17
ATE145918T1 (de) 1996-12-15

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090420