FI111552B - Menetelmä rekombinanttisen isäntäsolukannan tuottamiseksi ja näin saatu rekombinanttinen isäntäsolu - Google Patents

Menetelmä rekombinanttisen isäntäsolukannan tuottamiseksi ja näin saatu rekombinanttinen isäntäsolu Download PDF

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Publication number
FI111552B
FI111552B FI932559A FI932559A FI111552B FI 111552 B FI111552 B FI 111552B FI 932559 A FI932559 A FI 932559A FI 932559 A FI932559 A FI 932559A FI 111552 B FI111552 B FI 111552B
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Finland
Prior art keywords
gene
host cell
expression
mutation
ethanol
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FI932559A
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English (en)
Finnish (fi)
Swedish (sv)
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FI932559A0 (fi
FI932559A (fi
Inventor
Lonnie O Ingram
Kazuyoshi Ohta
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Univ Florida
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • C12N15/902Stable introduction of foreign DNA into chromosome using homologous recombination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • C12P7/065Ethanol, i.e. non-beverage with microorganisms other than yeasts
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI932559A 1990-12-07 1993-06-04 Menetelmä rekombinanttisen isäntäsolukannan tuottamiseksi ja näin saatu rekombinanttinen isäntäsolu FI111552B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US62422790A 1990-12-07 1990-12-07
US62422790 1990-12-07
PCT/US1991/008835 WO1992010561A1 (en) 1990-12-07 1991-12-04 Recombinant cells that highly express chromosomally-integrated heterologous genes
US9108835 1991-12-04

Publications (3)

Publication Number Publication Date
FI932559A0 FI932559A0 (fi) 1993-06-04
FI932559A FI932559A (fi) 1993-07-27
FI111552B true FI111552B (fi) 2003-08-15

Family

ID=24501169

Family Applications (1)

Application Number Title Priority Date Filing Date
FI932559A FI111552B (fi) 1990-12-07 1993-06-04 Menetelmä rekombinanttisen isäntäsolukannan tuottamiseksi ja näin saatu rekombinanttinen isäntäsolu

Country Status (12)

Country Link
EP (1) EP0560885B1 (da)
JP (2) JP3593125B2 (da)
AT (1) ATE177784T1 (da)
AU (3) AU668677B2 (da)
BR (1) BR9107210A (da)
CA (1) CA2097803C (da)
DE (1) DE69131015T2 (da)
DK (1) DK0560885T3 (da)
ES (1) ES2132116T3 (da)
FI (1) FI111552B (da)
GR (1) GR3030570T3 (da)
WO (1) WO1992010561A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5424202A (en) * 1988-08-31 1995-06-13 The University Of Florida Ethanol production by recombinant hosts
US5641670A (en) * 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
US5968502A (en) * 1991-11-05 1999-10-19 Transkaryotic Therapies, Inc. Protein production and protein delivery
TW402639B (en) * 1992-12-03 2000-08-21 Transkaryotic Therapies Inc Protein production and protein delivery
ATE244311T1 (de) 1993-12-23 2003-07-15 Merck & Co Inc Expressionssystem von antikörpern bei homologischer rekombinierung in murinezellen
US5958727A (en) * 1996-09-13 1999-09-28 Novo Nordisk Biotech, Inc Methods for modifying the production of a polypeptide
WO2001018222A1 (en) * 1999-09-07 2001-03-15 University Of Florida Methods and compositions for the chromosomal integration of heterologous sequences
KR100814313B1 (ko) * 2000-04-06 2008-03-18 교와 핫꼬 고교 가부시끼가이샤 대장균의 염색체 재조합에 사용되는 플라스미드
WO2001096573A1 (fr) 2000-06-16 2001-12-20 Research Institute Of Innovative Technology For The Earth Procede de production d'ethanol au moyen d'une bacterie coryneforme de recombinaison
US6566107B1 (en) * 2000-11-01 2003-05-20 Midwest Research Institute Recombinant Zymomonas mobilis with improved xylose utilization
NZ574777A (en) * 2006-08-09 2012-02-24 Univ Florida Re-engineering bacteria for ethanol production
JP5634710B2 (ja) * 2007-03-19 2014-12-03 国立大学法人 岡山大学 タンパク質産生用およびウイルス増殖用の培地

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4551433A (en) * 1981-05-18 1985-11-05 Genentech, Inc. Microbial hybrid promoters

Also Published As

Publication number Publication date
AU9098891A (en) 1992-07-08
WO1992010561A1 (en) 1992-06-25
ATE177784T1 (de) 1999-04-15
EP0560885A4 (en) 1994-06-08
DE69131015T2 (de) 1999-11-18
AU668677B2 (en) 1996-05-16
BR9107210A (pt) 1994-02-08
AU1858699A (en) 1999-09-09
DE69131015D1 (de) 1999-04-22
CA2097803A1 (en) 1992-06-08
GR3030570T3 (en) 1999-10-29
AU6194696A (en) 1996-10-31
FI932559A0 (fi) 1993-06-04
CA2097803C (en) 2010-08-03
JP3593125B2 (ja) 2004-11-24
JP2004283176A (ja) 2004-10-14
EP0560885B1 (en) 1999-03-17
FI932559A (fi) 1993-07-27
ES2132116T3 (es) 1999-08-16
AU694674B2 (en) 1998-07-23
DK0560885T3 (da) 1999-10-11
EP0560885A1 (en) 1993-09-22
JPH06504436A (ja) 1994-05-26

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