FI111130B - Menetelmä syklosporiinijohdannaista sisältävän farmaseuttisen koostumuksen valmistamiseksi - Google Patents

Menetelmä syklosporiinijohdannaista sisältävän farmaseuttisen koostumuksen valmistamiseksi Download PDF

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Publication number
FI111130B
FI111130B FI944978A FI944978A FI111130B FI 111130 B FI111130 B FI 111130B FI 944978 A FI944978 A FI 944978A FI 944978 A FI944978 A FI 944978A FI 111130 B FI111130 B FI 111130B
Authority
FI
Finland
Prior art keywords
weight
carrier medium
pharmaceutical composition
hydrophilic phase
composition
Prior art date
Application number
FI944978A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI944978A0 (fi
FI944978A (fi
Inventor
Jacky Vonderscher
Friedrich Richter
Armin Meinzer
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of FI944978A0 publication Critical patent/FI944978A0/fi
Publication of FI944978A publication Critical patent/FI944978A/fi
Application granted granted Critical
Publication of FI111130B publication Critical patent/FI111130B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
FI944978A 1992-04-22 1994-10-21 Menetelmä syklosporiinijohdannaista sisältävän farmaseuttisen koostumuksen valmistamiseksi FI111130B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB929208712A GB9208712D0 (en) 1992-04-22 1992-04-22 Pharmaceutical compositions containing cyclosporin derivates
GB9208712 1992-04-22
PCT/EP1993/000955 WO1993020833A1 (en) 1992-04-22 1993-04-20 Pharmaceutical composition containing cyclosporin derivative
EP9300955 1993-04-20

Publications (3)

Publication Number Publication Date
FI944978A0 FI944978A0 (fi) 1994-10-21
FI944978A FI944978A (fi) 1994-10-21
FI111130B true FI111130B (fi) 2003-06-13

Family

ID=10714386

Family Applications (1)

Application Number Title Priority Date Filing Date
FI944978A FI111130B (fi) 1992-04-22 1994-10-21 Menetelmä syklosporiinijohdannaista sisältävän farmaseuttisen koostumuksen valmistamiseksi

Country Status (22)

Country Link
EP (1) EP0637248B1 (no)
JP (1) JP2818298B2 (no)
KR (2) KR950701227A (no)
AT (1) ATE219940T1 (no)
AU (1) AU672793B2 (no)
CA (1) CA2132740C (no)
CY (1) CY2399B1 (no)
CZ (1) CZ287359B6 (no)
DE (1) DE69332078T2 (no)
DK (1) DK0637248T3 (no)
ES (1) ES2179052T3 (no)
FI (1) FI111130B (no)
GB (1) GB9208712D0 (no)
HU (1) HU218279B (no)
NO (1) NO315075B1 (no)
NZ (1) NZ252681A (no)
PT (1) PT637248E (no)
RU (1) RU2126263C1 (no)
SG (1) SG50692A1 (no)
SK (1) SK282745B6 (no)
UA (1) UA34454C2 (no)
WO (1) WO1993020833A1 (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
WO1993023010A1 (en) 1992-05-13 1993-11-25 Sandoz Ltd. Ophthalmic compositions containing a cyclosporin
ES2168271T3 (es) 1992-09-25 2002-06-16 Novartis Ag Composiciones farmaceuticas que contienen ciclosporinas.
CH686761A5 (de) * 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
GB2278780B (en) * 1993-05-27 1998-10-14 Sandoz Ltd Macrolide formulations
GB2315216B (en) * 1993-10-05 1998-10-14 Ciba Geigy Ag Microemulsion preconcentrates comprising FK506 or 33-epi-chloro-33-desoxy-ascomycin
EP0789580B1 (de) 1994-11-03 2002-06-05 Novartis AG Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung
HU215966B (hu) * 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
DE19544507B4 (de) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
GB9601120D0 (en) * 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
DE69823663T2 (de) * 1997-07-29 2005-05-19 Pharmacia & Upjohn Co., Kalamazoo Selbstemulgierbare formulierung enthaltend lipophile verbindungen
DE69808463T2 (de) * 1997-07-29 2003-06-26 Pharmacia & Upjohn Co., Kalamazoo Selbstemulgierende formulierung enthaltend saure lipophile verbindungen
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
US6187747B1 (en) 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
US6346511B1 (en) 1997-09-08 2002-02-12 Panacea Biotec Limited Pharmaceutical composition comprising cyclosporin
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
JP2005500314A (ja) 2001-06-21 2005-01-06 ファイザー・プロダクツ・インク コレステロールエステル転送蛋白インヒビターの自己乳化性製剤
US6828301B2 (en) 2002-02-07 2004-12-07 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for hepatitis C viral protease inhibitors
EP2204167A1 (en) * 2009-01-05 2010-07-07 Azad Pharma AG Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules
ME01718B (me) 2009-07-07 2014-09-20 Boehringer Ingelheim Int Farmaceutska kompozicija za inhibitor proteaze virusnog Hepatitis C

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI65914C (fi) * 1978-03-07 1984-08-10 Sandoz Ag Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
DE3884470T2 (de) * 1987-06-17 1994-03-10 Sandoz Ag Cyclosporine und deren Benutzung als Arzneimittel.
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물

Also Published As

Publication number Publication date
ES2179052T3 (es) 2003-01-16
WO1993020833A1 (en) 1993-10-28
DE69332078D1 (de) 2002-08-08
DE69332078T2 (de) 2002-12-19
PT637248E (pt) 2002-11-29
HU218279B (en) 2000-07-28
FI944978A0 (fi) 1994-10-21
CY2399B1 (en) 2004-09-10
EP0637248A1 (en) 1995-02-08
NO943998L (no) 1994-10-21
FI944978A (fi) 1994-10-21
RU94046413A (ru) 1996-11-10
SK282745B6 (sk) 2002-12-03
NO315075B1 (no) 2003-07-07
SG50692A1 (en) 1999-05-25
AU672793B2 (en) 1996-10-17
DK0637248T3 (da) 2002-10-28
AU4261193A (en) 1993-11-18
GB9208712D0 (en) 1992-06-10
RU2126263C1 (ru) 1999-02-20
KR950701227A (ko) 1995-03-23
CA2132740A1 (en) 1993-10-28
ATE219940T1 (de) 2002-07-15
HUT71580A (en) 1995-12-28
NZ252681A (en) 1996-02-27
JPH07505872A (ja) 1995-06-29
JP2818298B2 (ja) 1998-10-30
SK127294A3 (en) 1995-04-12
KR100414853B1 (no) 2004-01-13
EP0637248B1 (en) 2002-07-03
CZ261794A3 (en) 1995-02-15
HU9403055D0 (en) 1994-12-28
CA2132740C (en) 2008-01-15
UA34454C2 (uk) 2001-03-15
NO943998D0 (no) 1994-10-21
CZ287359B6 (en) 2000-11-15

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Owner name: NOVARTIS AG