FI108131B - Menetelmä terapeuttisesti käyttökelpoisen triatsolijohdannaisen valmistamiseksi sekä uusi välituote - Google Patents
Menetelmä terapeuttisesti käyttökelpoisen triatsolijohdannaisen valmistamiseksi sekä uusi välituote Download PDFInfo
- Publication number
- FI108131B FI108131B FI941644A FI941644A FI108131B FI 108131 B FI108131 B FI 108131B FI 941644 A FI941644 A FI 941644A FI 941644 A FI941644 A FI 941644A FI 108131 B FI108131 B FI 108131B
- Authority
- FI
- Finland
- Prior art keywords
- formula
- compound
- alkyl
- preparation
- process according
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cephalosporin Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9121456 | 1991-10-10 | ||
| GB919121456A GB9121456D0 (en) | 1991-10-10 | 1991-10-10 | Triazole antifungal agents |
| PCT/EP1992/002278 WO1993007139A1 (en) | 1991-10-10 | 1992-10-01 | Triazole antifungal agents |
| EP9202278 | 1992-10-01 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI941644A0 FI941644A0 (fi) | 1994-04-08 |
| FI941644A FI941644A (fi) | 1994-04-08 |
| FI108131B true FI108131B (fi) | 2001-11-30 |
Family
ID=10702663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI941644A FI108131B (fi) | 1991-10-10 | 1994-04-08 | Menetelmä terapeuttisesti käyttökelpoisen triatsolijohdannaisen valmistamiseksi sekä uusi välituote |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5541203A (ja) |
| EP (1) | EP0607193B1 (ja) |
| JP (1) | JPH07502022A (ja) |
| AT (1) | ATE196293T1 (ja) |
| CA (1) | CA2118937C (ja) |
| DE (1) | DE69231445T2 (ja) |
| DK (1) | DK0607193T3 (ja) |
| ES (1) | ES2149777T3 (ja) |
| FI (1) | FI108131B (ja) |
| GB (1) | GB9121456D0 (ja) |
| GR (1) | GR3034769T3 (ja) |
| PT (1) | PT100942B (ja) |
| WO (1) | WO1993007139A1 (ja) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9317491D0 (en) * | 1993-08-23 | 1993-10-06 | Fujisawa Pharmaceutical Co | New compound and a process for preparation thereof |
| NZ270418A (en) * | 1994-02-07 | 1997-09-22 | Eisai Co Ltd | Polycyclic triazole & imidazole derivatives, antifungal compositions |
| GB9512961D0 (en) * | 1995-06-26 | 1995-08-30 | Pfizer Ltd | Antifungal agents |
| GB9605705D0 (en) * | 1996-03-19 | 1996-05-22 | Pfizer Ltd | Therapeutic agents |
| KR100889937B1 (ko) * | 2007-08-06 | 2009-03-20 | 한미약품 주식회사 | 보리코나졸의 제조방법 |
| GB2452049A (en) * | 2007-08-21 | 2009-02-25 | Alpharma Aps | Process for the preparation of voriconazole |
| BR102012015179B1 (pt) * | 2011-06-19 | 2021-09-14 | Mycovia Pharmaceuticals, Inc | Métodos para tratar ou prevenir uma doença ou desordem mediada por metaloenzima ou fúngica, tratar ou prevenir o crescimento fúngico ou inibir micro-organismos em ou sobre uma planta e composições que compreendem compostos inibidores de metaloenzima |
| IN2014MN00093A (ja) * | 2011-06-19 | 2015-06-19 | Viamet Pharmaceuticals Inc | |
| DK2804858T3 (da) * | 2012-01-20 | 2020-03-16 | Mycovia Pharmaceuticals Inc | Metalloenzym-inhibitorforbindelser |
| TWI561515B (en) * | 2012-03-16 | 2016-12-11 | Viamet Pharmaceuticals Inc | Metalloenzyme inhibitor compounds |
| US11051514B2 (en) | 2015-05-18 | 2021-07-06 | Mycovia Pharmaceuticals, Inc. | Antifungal compounds |
| MA46075B1 (fr) * | 2016-11-22 | 2020-05-29 | Dow Agrosciences Llc | Composés et mélanges fongicides destinés à lutter contre les champignons dans les céréales |
| WO2018098256A1 (en) * | 2016-11-22 | 2018-05-31 | Vps-3, Inc. | Use of a difluoro-(2-hydroxypropyl)pyridine compound as a fungicide for control of phytopathogenic fungi of rice |
| UA124887C2 (uk) | 2016-11-22 | 2021-12-08 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Фунгіцидні сполуки і суміші для боротьби із грибковими захворюваннями зернових культур |
| RU2759948C2 (ru) * | 2016-11-22 | 2021-11-19 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Фунгицидные соединения и смеси для борьбы с грибковыми заболеваниями зерновых культур |
| US20190297890A1 (en) * | 2016-11-22 | 2019-10-03 | Dow Agrosciences Llc | Fungicidal compounds and mixtures for fungal control in cereals |
| EP3544429A4 (en) * | 2016-11-22 | 2020-04-29 | Dow Agrosciences Llc | USE OF A DIFLUOR (2-HYDROXYPROPYL) PYRIDINE COMPOUND AS A FUNGICIDE FOR COMBATING PHYTOPATHOGENIC MUSHROOMS OF WHEAT |
| AR110209A1 (es) * | 2016-11-22 | 2019-03-06 | Viamet Pharmaceuticals Inc | Uso de un compuesto de difluoro-(2-hidroxipropil)piridina como fungicida para el control de hongos fitopatógenos en maíz |
| EP3544433A4 (en) * | 2016-11-22 | 2020-04-29 | Dow AgroSciences LLC | FUNGICIDE COMPOUNDS AND MIXTURES FOR REGULATING MUSHROOMS IN CEREALS |
| RU2019118628A (ru) * | 2016-11-22 | 2020-12-24 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Применение соединений дифтор-(2-гидроксипропил)пиридина в качестве фунгицида для борьбы с пятнистостью листьев сахарной свеклы |
| JP2020500201A (ja) * | 2016-11-22 | 2020-01-09 | ダウ アグロサイエンシィズ エルエルシー | オオムギの植物病原性真菌の防除のための殺真菌剤としてのジフルオロ−（２−ヒドロキシプロピル）ピリジン化合物の使用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE322526C (de) * | 1918-08-31 | 1920-07-01 | Hermann Meyer | Sicherheitskettenverschluss fuer Korridortueren u. dgl. |
| DE3175673D1 (en) * | 1980-11-19 | 1987-01-15 | Ici Plc | Triazole compounds, a process for preparing them, their use as plant fungicides and fungicidal compositions containing them |
| ES523184A0 (es) * | 1982-06-17 | 1985-04-01 | Pfizer | Un procedimiento para la preparacion de un compuesto dotado de propiedades fungicidas |
| DE3245504A1 (de) * | 1982-12-09 | 1984-06-14 | Bayer Ag, 5090 Leverkusen | Fungizide mittel, deren herstellung und verwendung |
| US4952232A (en) * | 1987-04-29 | 1990-08-28 | E. I. Du Pont De Nemours And Company | Antifungal carbinols |
| DE3813841A1 (de) * | 1987-06-03 | 1988-12-15 | Bayer Ag | Heterocyclische hydroxyethylazole |
| DE3732385A1 (de) * | 1987-09-25 | 1989-04-06 | Bayer Ag | Hydroxyalkylcyclopropyl1-1,2,4-triazolyl- oder -imidazolyl-derivate und ihre verwendung als antimykotische mittel |
| WO1989005801A1 (en) * | 1987-12-17 | 1989-06-29 | E.I. Du Pont De Nemours And Company | Antifungal carbinols |
| DK105189A (da) * | 1988-03-04 | 1989-09-05 | Sankyo Co | Triazolderivater og fremgangsmaade til fremstilling deraf samt fungicide midler indeholdende derivaterne |
| GB8819308D0 (en) * | 1988-08-13 | 1988-09-14 | Pfizer Ltd | Triazole antifungal agents |
| GB9002375D0 (en) * | 1990-02-02 | 1990-04-04 | Pfizer Ltd | Triazole antifungal agents |
-
1991
- 1991-10-10 GB GB919121456A patent/GB9121456D0/en active Pending
-
1992
- 1992-10-01 AT AT92920368T patent/ATE196293T1/de not_active IP Right Cessation
- 1992-10-01 US US08/211,609 patent/US5541203A/en not_active Expired - Fee Related
- 1992-10-01 CA CA002118937A patent/CA2118937C/en not_active Expired - Fee Related
- 1992-10-01 EP EP92920368A patent/EP0607193B1/en not_active Expired - Lifetime
- 1992-10-01 ES ES92920368T patent/ES2149777T3/es not_active Expired - Lifetime
- 1992-10-01 DE DE69231445T patent/DE69231445T2/de not_active Expired - Fee Related
- 1992-10-01 JP JP5506608A patent/JPH07502022A/ja not_active Withdrawn
- 1992-10-01 DK DK92920368T patent/DK0607193T3/da active
- 1992-10-01 WO PCT/EP1992/002278 patent/WO1993007139A1/en active IP Right Grant
- 1992-10-09 PT PT100942A patent/PT100942B/pt active IP Right Grant
-
1994
- 1994-04-08 FI FI941644A patent/FI108131B/fi active
-
2000
- 2000-11-07 GR GR20000402458T patent/GR3034769T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GB9121456D0 (en) | 1991-11-27 |
| DE69231445D1 (de) | 2000-10-19 |
| WO1993007139A1 (en) | 1993-04-15 |
| EP0607193B1 (en) | 2000-09-13 |
| FI941644A0 (fi) | 1994-04-08 |
| JPH07502022A (ja) | 1995-03-02 |
| US5541203A (en) | 1996-07-30 |
| CA2118937C (en) | 1998-04-28 |
| PT100942A (pt) | 1993-10-29 |
| PT100942B (pt) | 1999-07-30 |
| DK0607193T3 (da) | 2000-10-09 |
| CA2118937A1 (en) | 1993-04-15 |
| ES2149777T3 (es) | 2000-11-16 |
| EP0607193A1 (en) | 1994-07-27 |
| DE69231445T2 (de) | 2001-01-11 |
| GR3034769T3 (en) | 2001-02-28 |
| FI941644A (fi) | 1994-04-08 |
| ATE196293T1 (de) | 2000-09-15 |
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