FI106843B - Menetelmä kolestipolihydrokloriditabletin valmistamiseksi - Google Patents

Menetelmä kolestipolihydrokloriditabletin valmistamiseksi Download PDF

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Publication number
FI106843B
FI106843B FI935943A FI935943A FI106843B FI 106843 B FI106843 B FI 106843B FI 935943 A FI935943 A FI 935943A FI 935943 A FI935943 A FI 935943A FI 106843 B FI106843 B FI 106843B
Authority
FI
Finland
Prior art keywords
tablet
povidone
att
triacetin
kännetecknat
Prior art date
Application number
FI935943A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI935943A (fi
FI935943A0 (fi
Inventor
Robert Wu-Wei Shen
Jeffrey Ellis Price
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FI935943A publication Critical patent/FI935943A/fi
Publication of FI935943A0 publication Critical patent/FI935943A0/fi
Application granted granted Critical
Publication of FI106843B publication Critical patent/FI106843B/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
FI935943A 1991-07-03 1993-12-30 Menetelmä kolestipolihydrokloriditabletin valmistamiseksi FI106843B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US72504491A 1991-07-03 1991-07-03
US72504491 1991-07-03
PCT/US1992/005066 WO1993000915A1 (en) 1991-07-03 1992-06-23 Colestipol hydrochloride high-content tablets
US9205066 1992-06-23

Publications (3)

Publication Number Publication Date
FI935943A FI935943A (fi) 1993-12-30
FI935943A0 FI935943A0 (fi) 1993-12-30
FI106843B true FI106843B (fi) 2001-04-30

Family

ID=24912923

Family Applications (1)

Application Number Title Priority Date Filing Date
FI935943A FI106843B (fi) 1991-07-03 1993-12-30 Menetelmä kolestipolihydrokloriditabletin valmistamiseksi

Country Status (18)

Country Link
US (1) US5490987A (de)
EP (1) EP0592594B1 (de)
JP (1) JP3313710B2 (de)
KR (1) KR100240362B1 (de)
AT (1) ATE173931T1 (de)
AU (1) AU669664B2 (de)
CA (1) CA2110166C (de)
CZ (1) CZ286958B6 (de)
DE (1) DE69227773T2 (de)
DK (1) DK0592594T3 (de)
ES (1) ES2124736T3 (de)
FI (1) FI106843B (de)
HU (1) HU222242B1 (de)
NO (1) NO307686B1 (de)
PL (1) PL169045B1 (de)
RU (1) RU2108090C1 (de)
SK (1) SK281920B6 (de)
WO (1) WO1993000915A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2129079C (en) * 1993-08-03 2006-01-17 Tatsuo Nomura Orally administrable cholesterol lowering agent
NZ503086A (en) * 1997-08-29 2002-03-01 Upjohn Co An orally administrable pharmaceutical composition comprising an inner core and two outer layers, which render it substantially free of unpleasant tastes
ATE286386T1 (de) * 1999-10-19 2005-01-15 Genzyme Corp Direktkomprimierter tablettenkern auf polymerbasis
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
EP1699442A2 (de) * 2003-12-31 2006-09-13 Genzyme Corporation Aliphatische amin-polymer-gallensäure-sequestriermittel mit magensaftresistentem überzug
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
JP2009507019A (ja) 2005-09-02 2009-02-19 ジェンザイム・コーポレーション リン酸塩を除去する方法およびそれに使用される重合体
KR101574072B1 (ko) 2005-09-15 2015-12-04 젠자임 코포레이션 아민 중합체에 대한 샤셋 제형
WO2008062437A2 (en) * 2006-09-01 2008-05-29 Usv Limited Process for the preparation of sevelamer hydrochloride and formulation thereof
US7964182B2 (en) * 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
EP2066293A2 (de) 2006-09-29 2009-06-10 Genzyme Corporation Amid-dendrimer-zusammensetzungen
WO2008076242A1 (en) 2006-12-14 2008-06-26 Genzyme Corporation Amido-amine polymer compositions
WO2010041268A2 (en) * 2008-09-02 2010-04-15 Usv Limited Crosslinked polymers
AU2010209293A1 (en) * 2009-01-22 2011-09-08 Usv Limited Pharmaceutical compositions comprising phosphate-binding polymer
US9763928B2 (en) * 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803237A (en) * 1969-11-03 1974-04-09 Upjohn Co Reaction products of polyethylenepolyamines and chlorohydrins or epoxy containing compounds
US3692895A (en) * 1970-09-08 1972-09-19 Norman A Nelson Method of reducing hypercholesteremia in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance, such as epichlorohydria
ZA804914B (en) * 1979-08-29 1981-08-26 Rohm & Haas The production of powdered resin and the powdered resin so produced
US4439419A (en) * 1980-02-20 1984-03-27 The Upjohn Company Method of treating gastric hyperacidity in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance as epichlorhydrin
US4404346A (en) * 1980-08-05 1983-09-13 Rohm And Haas Company Production of powdered resin and the powdered resin so produced
US4631305A (en) * 1985-03-22 1986-12-23 The Upjohn Company Polymeric material as a disintegrant in a compressed tablet
IE63242B1 (en) * 1988-06-24 1995-04-05 Abbott Lab Pharmaceutical granules and tablets made therefrom
KR0152438B1 (ko) * 1988-06-24 1998-10-15 로버트 에이. 아미테이지 미분된 콜레스티폴 하이드로클로라이드
EP0429541B1 (de) * 1988-08-26 1993-12-01 The Upjohn Company Feinkörniges colestipol hydrochlorid

Also Published As

Publication number Publication date
ES2124736T3 (es) 1999-02-16
AU2293392A (en) 1993-02-11
AU669664B2 (en) 1996-06-20
CZ286958B6 (cs) 2000-08-16
HUT69394A (en) 1995-09-28
JP3313710B2 (ja) 2002-08-12
PL169045B1 (pl) 1996-05-31
FI935943A (fi) 1993-12-30
JPH06509097A (ja) 1994-10-13
US5490987A (en) 1996-02-13
DE69227773T2 (de) 1999-05-20
NO940008L (no) 1994-01-03
NO307686B1 (no) 2000-05-15
RU2108090C1 (ru) 1998-04-10
CA2110166A1 (en) 1993-01-21
CA2110166C (en) 2002-11-05
CZ282693A3 (en) 1994-06-15
DE69227773D1 (de) 1999-01-14
HU9400004D0 (en) 1994-05-30
KR100240362B1 (ko) 2000-02-01
SK194A3 (en) 1994-11-09
SK281920B6 (sk) 2001-09-11
NO940008D0 (no) 1994-01-03
ATE173931T1 (de) 1998-12-15
HU222242B1 (hu) 2003-05-28
EP0592594B1 (de) 1998-12-02
FI935943A0 (fi) 1993-12-30
EP0592594A1 (de) 1994-04-20
WO1993000915A1 (en) 1993-01-21
DK0592594T3 (da) 1999-08-16

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Owner name: PHARMACIA & UPJOHN COMPANY

MA Patent expired