DE69227773D1 - Tabletten mit hohem gehalt an colestipolhydrochlorid - Google Patents

Tabletten mit hohem gehalt an colestipolhydrochlorid

Info

Publication number
DE69227773D1
DE69227773D1 DE69227773T DE69227773T DE69227773D1 DE 69227773 D1 DE69227773 D1 DE 69227773D1 DE 69227773 T DE69227773 T DE 69227773T DE 69227773 T DE69227773 T DE 69227773T DE 69227773 D1 DE69227773 D1 DE 69227773D1
Authority
DE
Germany
Prior art keywords
tablet
scus
mins
excipients
inch
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69227773T
Other languages
English (en)
Other versions
DE69227773T2 (de
Inventor
Robert Shen
Jeffrey Price
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Application granted granted Critical
Publication of DE69227773D1 publication Critical patent/DE69227773D1/de
Publication of DE69227773T2 publication Critical patent/DE69227773T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
DE69227773T 1991-07-03 1992-06-23 Tabletten mit hohem gehalt an colestipolhydrochlorid Expired - Lifetime DE69227773T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72504491A 1991-07-03 1991-07-03
PCT/US1992/005066 WO1993000915A1 (en) 1991-07-03 1992-06-23 Colestipol hydrochloride high-content tablets

Publications (2)

Publication Number Publication Date
DE69227773D1 true DE69227773D1 (de) 1999-01-14
DE69227773T2 DE69227773T2 (de) 1999-05-20

Family

ID=24912923

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69227773T Expired - Lifetime DE69227773T2 (de) 1991-07-03 1992-06-23 Tabletten mit hohem gehalt an colestipolhydrochlorid

Country Status (18)

Country Link
US (1) US5490987A (de)
EP (1) EP0592594B1 (de)
JP (1) JP3313710B2 (de)
KR (1) KR100240362B1 (de)
AT (1) ATE173931T1 (de)
AU (1) AU669664B2 (de)
CA (1) CA2110166C (de)
CZ (1) CZ286958B6 (de)
DE (1) DE69227773T2 (de)
DK (1) DK0592594T3 (de)
ES (1) ES2124736T3 (de)
FI (1) FI106843B (de)
HU (1) HU222242B1 (de)
NO (1) NO307686B1 (de)
PL (1) PL169045B1 (de)
RU (1) RU2108090C1 (de)
SK (1) SK281920B6 (de)
WO (1) WO1993000915A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2129079C (en) * 1993-08-03 2006-01-17 Tatsuo Nomura Orally administrable cholesterol lowering agent
NZ503086A (en) * 1997-08-29 2002-03-01 Upjohn Co An orally administrable pharmaceutical composition comprising an inner core and two outer layers, which render it substantially free of unpleasant tastes
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
ES2235969T3 (es) * 1999-10-19 2005-07-16 Genzyme Corporation Nucleo de comprimido polimerico por compresion directa.
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
JP2007517047A (ja) * 2003-12-31 2007-06-28 ジェンザイム・コーポレーション 腸溶コーティングされた脂肪族アミンポリマーの胆汁酸捕捉因子
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US8986669B2 (en) 2005-09-02 2015-03-24 Genzyme Corporation Method for removing phosphate and polymer used therefore
WO2007035313A2 (en) 2005-09-15 2007-03-29 Genzyme Corporation Sachet formulation for amine polymers
US7964182B2 (en) * 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
RU2009111853A (ru) * 2006-09-01 2010-10-10 Юсв Лимитед (In) Способ получения гидрохлорида севеламера и его лекарственной формы
JP2010504975A (ja) 2006-09-29 2010-02-18 ゲンズイメ コーポレーション アミドデンドリマー組成物
BRPI0720234A2 (pt) 2006-12-14 2013-12-24 Genzyme Corp Composição farmacêutica
RU2011112694A (ru) * 2008-09-02 2012-10-10 Юсв Лимитед (In) Сшитые полимеры
US20110081413A1 (en) * 2009-01-22 2011-04-07 Ashok Omray Pharmaceutical Compositions Comprising Phosphate-Binding Polymer
US9763928B2 (en) * 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803237A (en) * 1969-11-03 1974-04-09 Upjohn Co Reaction products of polyethylenepolyamines and chlorohydrins or epoxy containing compounds
US3692895A (en) * 1970-09-08 1972-09-19 Norman A Nelson Method of reducing hypercholesteremia in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance, such as epichlorohydria
ZA804914B (en) * 1979-08-29 1981-08-26 Rohm & Haas The production of powdered resin and the powdered resin so produced
US4439419A (en) * 1980-02-20 1984-03-27 The Upjohn Company Method of treating gastric hyperacidity in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance as epichlorhydrin
US4404346A (en) * 1980-08-05 1983-09-13 Rohm And Haas Company Production of powdered resin and the powdered resin so produced
US4631305A (en) * 1985-03-22 1986-12-23 The Upjohn Company Polymeric material as a disintegrant in a compressed tablet
IE63242B1 (en) * 1988-06-24 1995-04-05 Abbott Lab Pharmaceutical granules and tablets made therefrom
DE68907721T2 (de) * 1988-06-24 1993-11-18 Upjohn Co Feingemahlenes colestipol-hydrochlorid.
KR900701285A (ko) * 1988-08-26 1990-12-01 로버어트 에이 아미테이지 미세-구슬상 콜레스티폴 염산염

Also Published As

Publication number Publication date
CZ282693A3 (en) 1994-06-15
FI935943A0 (fi) 1993-12-30
NO307686B1 (no) 2000-05-15
SK194A3 (en) 1994-11-09
CA2110166A1 (en) 1993-01-21
NO940008D0 (no) 1994-01-03
ATE173931T1 (de) 1998-12-15
DE69227773T2 (de) 1999-05-20
FI935943A (fi) 1993-12-30
PL169045B1 (pl) 1996-05-31
US5490987A (en) 1996-02-13
KR100240362B1 (ko) 2000-02-01
HU222242B1 (hu) 2003-05-28
AU2293392A (en) 1993-02-11
EP0592594A1 (de) 1994-04-20
RU2108090C1 (ru) 1998-04-10
CZ286958B6 (cs) 2000-08-16
JPH06509097A (ja) 1994-10-13
EP0592594B1 (de) 1998-12-02
HU9400004D0 (en) 1994-05-30
SK281920B6 (sk) 2001-09-11
NO940008L (no) 1994-01-03
AU669664B2 (en) 1996-06-20
WO1993000915A1 (en) 1993-01-21
ES2124736T3 (es) 1999-02-16
JP3313710B2 (ja) 2002-08-12
DK0592594T3 (da) 1999-08-16
CA2110166C (en) 2002-11-05
HUT69394A (en) 1995-09-28
FI106843B (fi) 2001-04-30

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R071 Expiry of right

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