FI106843B - Menetelmä kolestipolihydrokloriditabletin valmistamiseksi - Google Patents

Menetelmä kolestipolihydrokloriditabletin valmistamiseksi Download PDF

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Publication number
FI106843B
FI106843B FI935943A FI935943A FI106843B FI 106843 B FI106843 B FI 106843B FI 935943 A FI935943 A FI 935943A FI 935943 A FI935943 A FI 935943A FI 106843 B FI106843 B FI 106843B
Authority
FI
Finland
Prior art keywords
tablet
povidone
att
triacetin
kännetecknat
Prior art date
Application number
FI935943A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI935943L (fi
FI935943A0 (fi
Inventor
Robert Wu-Wei Shen
Jeffrey Ellis Price
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FI935943L publication Critical patent/FI935943L/fi
Publication of FI935943A0 publication Critical patent/FI935943A0/fi
Application granted granted Critical
Publication of FI106843B publication Critical patent/FI106843B/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
FI935943A 1991-07-03 1993-12-30 Menetelmä kolestipolihydrokloriditabletin valmistamiseksi FI106843B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US72504491A 1991-07-03 1991-07-03
US72504491 1991-07-03
US9205066 1992-06-23
PCT/US1992/005066 WO1993000915A1 (en) 1991-07-03 1992-06-23 Colestipol hydrochloride high-content tablets

Publications (3)

Publication Number Publication Date
FI935943L FI935943L (fi) 1993-12-30
FI935943A0 FI935943A0 (fi) 1993-12-30
FI106843B true FI106843B (fi) 2001-04-30

Family

ID=24912923

Family Applications (1)

Application Number Title Priority Date Filing Date
FI935943A FI106843B (fi) 1991-07-03 1993-12-30 Menetelmä kolestipolihydrokloriditabletin valmistamiseksi

Country Status (18)

Country Link
US (1) US5490987A (cs)
EP (1) EP0592594B1 (cs)
JP (1) JP3313710B2 (cs)
KR (1) KR100240362B1 (cs)
AT (1) ATE173931T1 (cs)
AU (1) AU669664B2 (cs)
CA (1) CA2110166C (cs)
CZ (1) CZ286958B6 (cs)
DE (1) DE69227773T2 (cs)
DK (1) DK0592594T3 (cs)
ES (1) ES2124736T3 (cs)
FI (1) FI106843B (cs)
HU (1) HU222242B1 (cs)
NO (1) NO307686B1 (cs)
PL (1) PL169045B1 (cs)
RU (1) RU2108090C1 (cs)
SK (1) SK281920B6 (cs)
WO (1) WO1993000915A1 (cs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2129079C (en) * 1993-08-03 2006-01-17 Tatsuo Nomura Orally administrable cholesterol lowering agent
NZ503086A (en) * 1997-08-29 2002-03-01 Upjohn Co An orally administrable pharmaceutical composition comprising an inner core and two outer layers, which render it substantially free of unpleasant tastes
ATE286386T1 (de) * 1999-10-19 2005-01-15 Genzyme Corp Direktkomprimierter tablettenkern auf polymerbasis
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
AU2004311849B2 (en) * 2003-12-31 2009-04-02 Genzyme Corporation Enteric coated aliphatic amine polymer bile acid sequestrants
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
CA2620406A1 (en) 2005-09-02 2007-03-08 Genzyme Corporation Method for removing phosphate and polymer used therefore
PT1924246E (pt) 2005-09-15 2016-02-10 Genzyme Corp Formulação sachê para polímeros com funcionalidade amina
BRPI0717008A2 (pt) * 2006-09-01 2014-01-21 Usv Ltd Processo para o preparo de cloridrato de sevelamer e formulação do mesmo
US7964182B2 (en) * 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
BRPI0717545A2 (pt) 2006-09-29 2013-10-22 Gezyme Corp Composição farmacêutica, método para tratar uma doença, polímero de amida, rede de polímero, e, método para preparar um polímero de amida
EP2120972A1 (en) 2006-12-14 2009-11-25 Genzyme Corporation Amido-amine polymer compositions
CA2735962A1 (en) * 2008-09-02 2010-04-15 Usv Limited Crosslinked polymers
AU2010209293A1 (en) * 2009-01-22 2011-09-08 Usv Limited Pharmaceutical compositions comprising phosphate-binding polymer
US9763928B2 (en) * 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803237A (en) * 1969-11-03 1974-04-09 Upjohn Co Reaction products of polyethylenepolyamines and chlorohydrins or epoxy containing compounds
US3692895A (en) * 1970-09-08 1972-09-19 Norman A Nelson Method of reducing hypercholesteremia in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance, such as epichlorohydria
ZA804914B (en) * 1979-08-29 1981-08-26 Rohm & Haas The production of powdered resin and the powdered resin so produced
US4439419A (en) * 1980-02-20 1984-03-27 The Upjohn Company Method of treating gastric hyperacidity in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance as epichlorhydrin
US4404346A (en) * 1980-08-05 1983-09-13 Rohm And Haas Company Production of powdered resin and the powdered resin so produced
US4631305A (en) * 1985-03-22 1986-12-23 The Upjohn Company Polymeric material as a disintegrant in a compressed tablet
CS255081B1 (cs) * 1985-12-21 1988-02-15 Arnost Pospisil Způsob Výroby tablet s časové řízenou liberací obsahující nestálou a/nabo dráidivou fyziologicky aktivní složku
ATE91627T1 (de) * 1988-06-24 1993-08-15 Upjohn Co Feingemahlenes colestipol-hydrochlorid.
IE63242B1 (en) * 1988-06-24 1995-04-05 Abbott Lab Pharmaceutical granules and tablets made therefrom
DE68911146T2 (de) * 1988-08-26 1994-04-14 Upjohn Co Feinkörniges colestipol hydrochlorid.

Also Published As

Publication number Publication date
FI935943L (fi) 1993-12-30
HUT69394A (en) 1995-09-28
WO1993000915A1 (en) 1993-01-21
FI935943A0 (fi) 1993-12-30
US5490987A (en) 1996-02-13
JPH06509097A (ja) 1994-10-13
DE69227773D1 (de) 1999-01-14
JP3313710B2 (ja) 2002-08-12
EP0592594B1 (en) 1998-12-02
RU2108090C1 (ru) 1998-04-10
EP0592594A1 (en) 1994-04-20
PL169045B1 (pl) 1996-05-31
NO940008D0 (no) 1994-01-03
SK281920B6 (sk) 2001-09-11
CA2110166C (en) 2002-11-05
DE69227773T2 (de) 1999-05-20
CA2110166A1 (en) 1993-01-21
HU222242B1 (hu) 2003-05-28
DK0592594T3 (da) 1999-08-16
HU9400004D0 (en) 1994-05-30
NO307686B1 (no) 2000-05-15
CZ282693A3 (en) 1994-06-15
KR100240362B1 (ko) 2000-02-01
ATE173931T1 (de) 1998-12-15
AU2293392A (en) 1993-02-11
AU669664B2 (en) 1996-06-20
ES2124736T3 (es) 1999-02-16
CZ286958B6 (cs) 2000-08-16
SK194A3 (en) 1994-11-09
NO940008L (no) 1994-01-03

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HC Name/ company changed in application

Owner name: PHARMACIA & UPJOHN COMPANY

MA Patent expired