FI106454B - Menetelmä 4-[4-[4-(hydroksidifenyylimetyyli)-1-piperidinyyli]-1-hydroksibutyyli]- ja 4-[4-[4-(hydroksidifenyylimetyyli)-1-piperidinyyli]-1-oksobutyyli]johdannaisten valmistamiseksi - Google Patents
Menetelmä 4-[4-[4-(hydroksidifenyylimetyyli)-1-piperidinyyli]-1-hydroksibutyyli]- ja 4-[4-[4-(hydroksidifenyylimetyyli)-1-piperidinyyli]-1-oksobutyyli]johdannaisten valmistamiseksi Download PDFInfo
- Publication number
- FI106454B FI106454B FI944713A FI944713A FI106454B FI 106454 B FI106454 B FI 106454B FI 944713 A FI944713 A FI 944713A FI 944713 A FI944713 A FI 944713A FI 106454 B FI106454 B FI 106454B
- Authority
- FI
- Finland
- Prior art keywords
- piperidinyl
- hydroxydiphenylmethyl
- oxobutyl
- formula
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86726192A | 1992-04-10 | 1992-04-10 | |
US86726192 | 1992-04-10 | ||
US1725193A | 1993-02-25 | 1993-02-25 | |
US1725193 | 1993-02-25 | ||
PCT/US1993/002103 WO1993021156A1 (en) | 1992-04-10 | 1993-03-10 | 4-diphenylmethyl piperidine derivatives and process for their preparation |
US9302103 | 1993-03-10 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI944713A0 FI944713A0 (fi) | 1994-10-07 |
FI944713A FI944713A (fi) | 1994-12-02 |
FI106454B true FI106454B (fi) | 2001-02-15 |
Family
ID=26689638
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI944713A FI106454B (fi) | 1992-04-10 | 1994-10-07 | Menetelmä 4-[4-[4-(hydroksidifenyylimetyyli)-1-piperidinyyli]-1-hydroksibutyyli]- ja 4-[4-[4-(hydroksidifenyylimetyyli)-1-piperidinyyli]-1-oksobutyyli]johdannaisten valmistamiseksi |
FI20002460A FI20002460A (fi) | 1992-04-10 | 2000-11-09 | 4-difenyylimetyylipiperidiinijohdannaisia |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI20002460A FI20002460A (fi) | 1992-04-10 | 2000-11-09 | 4-difenyylimetyylipiperidiinijohdannaisia |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0635004B1 (ja) |
JP (3) | JP3686950B2 (ja) |
KR (1) | KR100257805B1 (ja) |
AR (1) | AR253777A1 (ja) |
AT (1) | ATE220666T1 (ja) |
AU (1) | AU671822B2 (ja) |
CA (1) | CA2117892C (ja) |
DE (1) | DE69332117T2 (ja) |
DK (1) | DK0635004T3 (ja) |
ES (1) | ES2176201T3 (ja) |
FI (2) | FI106454B (ja) |
HU (1) | HU226561B1 (ja) |
IL (1) | IL105328A (ja) |
MX (1) | MX9302076A (ja) |
NO (5) | NO305076B1 (ja) |
NZ (1) | NZ251132A (ja) |
PT (1) | PT635004E (ja) |
TW (1) | TW362096B (ja) |
WO (1) | WO1993021156A1 (ja) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SK12495A3 (en) * | 1992-08-03 | 1997-01-08 | Sepracor Inc | Drug manufacturing process for use at antihistaminic treatment |
US20020007068A1 (en) | 1999-07-16 | 2002-01-17 | D'ambra Thomas E. | Piperidine derivatives and process for their production |
KR100387347B1 (ko) * | 1993-06-24 | 2003-11-28 | 알바니 몰레큘라 리써치, 인크. | 피페리딘 유도체 및 그의 제조 방법 |
US6147216A (en) * | 1993-06-25 | 2000-11-14 | Merrell Pharmaceuticals Inc. | Intermediates useful for the preparation of antihistaminic piperidine derivatives |
EP2261207A1 (en) | 1993-06-25 | 2010-12-15 | Aventisub II Inc. | Intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives |
WO1995031437A1 (en) * | 1994-05-18 | 1995-11-23 | Hoechst Marrion Roussel, Inc. | Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudormophs thereof |
NZ302926A (en) | 1995-02-28 | 1998-10-28 | Hoechst Marion Roussel Inc | Composition for use as antihistamines comprising piperidinoalkanol derivatives and inert ingredients |
US6153754A (en) * | 1995-12-21 | 2000-11-28 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
US6201124B1 (en) | 1995-12-21 | 2001-03-13 | Albany Molecular Research, Inc. | Process for production of piperidine derivatives |
CN1246312C (zh) * | 1998-07-02 | 2006-03-22 | 阿旺蒂斯制药公司 | 新的抗组胺哌啶衍生物及制备其的中间体 |
WO2002080857A2 (en) * | 2001-04-09 | 2002-10-17 | Teva Pharmaceutical Industries Ltd. | Polymorphs of fexofenadine hydrochloride |
ITRM20010260A1 (it) | 2001-05-17 | 2002-11-18 | Dinamite Dipharma S P A In For | Processo per la preparazione della fexofenadina o acido 4 1-idrossi-4-4- (idrossidifenilmetil)-1-piperidinil|-butil|-alfa,alfa-dimetilbenz |
US6743941B2 (en) * | 2001-06-15 | 2004-06-01 | Aventis Pharma Deutschland Gmbh | Process for the production of piperidine derivatives |
EP1474392A1 (en) | 2002-06-10 | 2004-11-10 | Teva Pharmaceutical Industries Ltd. | Polymorphic form xvi of fexofenadine hydrochloride |
GB0319935D0 (en) | 2003-08-26 | 2003-09-24 | Cipla Ltd | Polymorphs |
ITMI20061492A1 (it) * | 2006-07-27 | 2008-01-28 | Archimica Srl | Processo per la preparazione di fexofenadina. |
ITMI20070987A1 (it) | 2007-05-16 | 2008-11-17 | Dipharma Francis Srl | Procedimento per la preparazione di composti chetonici |
EP2289867A3 (en) | 2009-08-19 | 2012-04-25 | Jubilant Organosys Limited | A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4254129A (en) * | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
US4254130A (en) * | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
-
1993
- 1993-03-10 CA CA002117892A patent/CA2117892C/en not_active Expired - Lifetime
- 1993-03-10 JP JP51831393A patent/JP3686950B2/ja not_active Expired - Lifetime
- 1993-03-10 AT AT93907333T patent/ATE220666T1/de active
- 1993-03-10 WO PCT/US1993/002103 patent/WO1993021156A1/en active IP Right Grant
- 1993-03-10 EP EP93907333A patent/EP0635004B1/en not_active Expired - Lifetime
- 1993-03-10 NZ NZ251132A patent/NZ251132A/en not_active IP Right Cessation
- 1993-03-10 HU HU9402913A patent/HU226561B1/hu unknown
- 1993-03-10 ES ES93907333T patent/ES2176201T3/es not_active Expired - Lifetime
- 1993-03-10 DK DK93907333T patent/DK0635004T3/da active
- 1993-03-10 MX MX9302076A patent/MX9302076A/es unknown
- 1993-03-10 AU AU37973/93A patent/AU671822B2/en not_active Expired
- 1993-03-10 PT PT93907333T patent/PT635004E/pt unknown
- 1993-03-10 DE DE69332117T patent/DE69332117T2/de not_active Expired - Lifetime
- 1993-03-10 KR KR1019940703575A patent/KR100257805B1/ko not_active IP Right Cessation
- 1993-04-07 TW TW082102558A patent/TW362096B/zh not_active IP Right Cessation
- 1993-04-07 AR AR25377793A patent/AR253777A1/es unknown
- 1993-04-07 IL IL105328A patent/IL105328A/en not_active IP Right Cessation
-
1994
- 1994-10-07 NO NO943794A patent/NO305076B1/no not_active IP Right Cessation
- 1994-10-07 FI FI944713A patent/FI106454B/fi not_active IP Right Cessation
-
1998
- 1998-03-30 NO NO981433A patent/NO305024B1/no not_active IP Right Cessation
- 1998-03-30 NO NO981434A patent/NO305025B1/no not_active IP Right Cessation
- 1998-03-30 NO NO981432A patent/NO305077B1/no not_active IP Right Cessation
- 1998-03-30 NO NO981431A patent/NO305023B1/no not_active IP Right Cessation
-
2000
- 2000-11-09 FI FI20002460A patent/FI20002460A/fi unknown
-
2004
- 2004-05-06 JP JP2004137675A patent/JP4266184B2/ja not_active Expired - Lifetime
-
2005
- 2005-04-01 JP JP2005105603A patent/JP2005213268A/ja active Pending
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Transfer of assignment of patent |
Owner name: AVENTIS INC. Free format text: AVENTIS INC. |
|
PC | Transfer of assignment of patent |
Owner name: AVENTISUB II INC. Free format text: AVENTISUB II INC. |
|
MA | Patent expired |