FI104638B - Menetelmä flagelliinifuusioproteiinin, sitä koodaavan geenin ja mikro-organismin valmistamiseksi - Google Patents

Menetelmä flagelliinifuusioproteiinin, sitä koodaavan geenin ja mikro-organismin valmistamiseksi Download PDF

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Publication number
FI104638B
FI104638B FI905441A FI905441A FI104638B FI 104638 B FI104638 B FI 104638B FI 905441 A FI905441 A FI 905441A FI 905441 A FI905441 A FI 905441A FI 104638 B FI104638 B FI 104638B
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FI
Finland
Prior art keywords
flagellin
epitope
recombinant
gene
protein
Prior art date
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FI905441A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI905441A0 (fi
Inventor
William Robert Marjarian
Salete Maria Cardozo Newton
Bruce Arnold Dunbar Stocker
Original Assignee
Univ Leland Stanford Junior
American Cyanamid Co
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Publication date
Application filed by Univ Leland Stanford Junior, American Cyanamid Co filed Critical Univ Leland Stanford Junior
Publication of FI905441A0 publication Critical patent/FI905441A0/fi
Application granted granted Critical
Publication of FI104638B publication Critical patent/FI104638B/fi

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445Plasmodium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/55Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI905441A 1988-05-05 1990-11-02 Menetelmä flagelliinifuusioproteiinin, sitä koodaavan geenin ja mikro-organismin valmistamiseksi FI104638B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US19057088A 1988-05-05 1988-05-05
US19057088 1988-05-05
US8901932 1989-05-05
PCT/US1989/001932 WO1989010967A1 (en) 1988-05-05 1989-05-05 Recombinant flagellin vaccines

Publications (2)

Publication Number Publication Date
FI905441A0 FI905441A0 (fi) 1990-11-02
FI104638B true FI104638B (fi) 2000-03-15

Family

ID=22701885

Family Applications (1)

Application Number Title Priority Date Filing Date
FI905441A FI104638B (fi) 1988-05-05 1990-11-02 Menetelmä flagelliinifuusioproteiinin, sitä koodaavan geenin ja mikro-organismin valmistamiseksi

Country Status (10)

Country Link
EP (1) EP0419513B1 (da)
JP (1) JP2793673B2 (da)
AT (1) ATE121782T1 (da)
AU (1) AU637049B2 (da)
CA (1) CA1340817C (da)
DE (1) DE68922394T2 (da)
DK (1) DK263390A (da)
FI (1) FI104638B (da)
NO (1) NO302031B1 (da)
WO (1) WO1989010967A1 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714596A (en) * 1987-11-18 1998-02-03 Chiron Corporation NANBV diagnostics: polynucleotides useful for screening for hepatitis C virus
US5712088A (en) * 1987-11-18 1998-01-27 Chiron Corporation Methods for detecting Hepatitis C virus using polynucleotides specific for same
US6861212B1 (en) 1987-11-18 2005-03-01 Chiron Corporation NANBV diagnostics and vaccines
US5698390A (en) * 1987-11-18 1997-12-16 Chiron Corporation Hepatitis C immunoassays
US6171782B1 (en) 1987-11-18 2001-01-09 Chiron Corporation Antibody compositions to HCV and uses thereof
AU640118B2 (en) * 1988-12-19 1993-08-19 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur Meningococcal class 1 outer-membrane protein vaccine
US7118757B1 (en) 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
US6027729A (en) * 1989-04-20 2000-02-22 Chiron Corporation NANBV Diagnostics and vaccines
IE913456A1 (en) * 1990-10-01 1992-04-08 Mini Agriculture & Fisheries Salmonella polynucleotide sequence
JPH06501934A (ja) * 1990-10-01 1994-03-03 イギリス国 サルモネラのテスト法
GB9101550D0 (en) * 1991-01-24 1991-03-06 Mastico Robert A Antigen-presenting chimaeric protein
IL101639A0 (en) * 1992-04-17 1992-12-30 Yeda Res & Dev Recombinant influenza vaccines
TR200401569T4 (tr) * 1999-12-28 2004-07-21 Akzo Nobel N.V. Flagelin ya da flagelle'ya karşı antikorların oluşumuna sebep olmayan salmonelle aşısı
JPWO2004055045A1 (ja) * 2002-12-16 2006-04-20 株式会社シーエーエフラボラトリーズ サルモネラ抗原処方物、それを使用した抗体検査キット及びサブユニットワクチン
WO2005107381A2 (en) 2004-05-07 2005-11-17 Hans-Gustaf Ljunggren Use of flagellin as an adjuvant for vaccine
RU2007124731A (ru) * 2004-12-02 2009-01-10 Ксир (Za) Грамположительные бактерии, продуцирующие рекомбинантные белки
AU2005325715B2 (en) 2004-12-16 2011-10-06 Wake Forest University Health Sciences Use of flagellin in tumor immunotherapy
CA2594612A1 (en) 2005-01-19 2006-07-27 Vaxinnate Corporation Compositions comprising pathogen-associated molecular patterns and antigens and their use to stimulate an immune response
CA2638760A1 (en) 2006-03-07 2007-09-13 Vaxinnate Corporation Compositions that include hemagglutinin, methods of making and methods of use thereof
JP2011519828A (ja) 2008-04-18 2011-07-14 バクシネート コーポレーション フラジェリンの欠失変異体と使用方法
US8932598B2 (en) 2012-08-28 2015-01-13 Vaxinnate Corporation Fusion proteins and methods of use
CN102816246B (zh) * 2012-09-04 2014-07-23 成都蓉生药业有限责任公司 一种人巨细胞病毒免疫原融合蛋白及其制备方法和用途
NZ729519A (en) 2014-09-26 2024-02-23 Bavarian Nordic As Methods and compositions for intra-nasal immunization with recombinant mva encoding flagellin
EP3221464B1 (en) * 2014-11-18 2022-02-23 The Trustees of Columbia University in the City of New York Detection of analytes using live cells
CN104402974B (zh) * 2014-12-10 2017-11-14 重庆医科大学 一种具有粘膜免疫佐剂活性的多肽及其在制备粘膜免疫佐剂中的用途
US10849938B2 (en) 2017-09-13 2020-12-01 ZBiotics Company Gene expression system for probiotic microorganisms

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735801A (en) * 1982-09-07 1988-04-05 Board Of Trustees Of Leland Stanford Jr. University Novel non-reverting salmonella live vaccines
WO1987002385A1 (en) * 1985-10-11 1987-04-23 Genetics Institute, Inc. Method for producing heterologous proteins
US4886748A (en) * 1986-03-11 1989-12-12 Shionogi & Co., Ltd. DNA encoding flagellin and vector having the same
CA1331355C (en) * 1986-04-21 1994-08-09 Bioenterprises Pty. Ltd Immunopotentation

Also Published As

Publication number Publication date
NO302031B1 (no) 1998-01-12
DK263390A (da) 1991-01-04
EP0419513A1 (en) 1991-04-03
AU637049B2 (en) 1993-05-20
DK263390D0 (da) 1990-11-02
JP2793673B2 (ja) 1998-09-03
DE68922394D1 (de) 1995-06-01
ATE121782T1 (de) 1995-05-15
JPH04502402A (ja) 1992-05-07
CA1340817C (en) 1999-11-09
DE68922394T2 (de) 1995-10-05
FI905441A0 (fi) 1990-11-02
AU3697989A (en) 1989-11-29
EP0419513B1 (en) 1995-04-26
NO904806D0 (no) 1990-11-05
WO1989010967A1 (en) 1989-11-16
NO904806L (no) 1991-01-03

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Date Code Title Description
GB Transfer or assigment of application

Owner name: AMERICAN CYANAMID COMPANY

FG Patent granted

Owner name: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO

Owner name: AMERICAN CYANAMID COMPANY

MA Patent expired