FI103890B1 - Menetelmä terapeuttisesti käyttökelpoisten pyratsolo[4,3-c]pyridiinien valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten pyratsolo[4,3-c]pyridiinien valmistamiseksi

Info

Publication number
FI103890B1
FI103890B1 FI934621A FI934621A FI103890B1 FI 103890 B1 FI103890 B1 FI 103890B1 FI 934621 A FI934621 A FI 934621A FI 934621 A FI934621 A FI 934621A FI 103890 B1 FI103890 B1 FI 103890B1
Authority
FI
Finland
Prior art keywords
loweralkyl
chem
hydrogen
pyridines
preparation
Prior art date
Application number
FI934621A
Other languages
English (en)
Swedish (sv)
Other versions
FI103890B (fi
FI934621A0 (fi
FI934621A (fi
Inventor
Gregory M Shutske
Kevin J Kapples
John D Tomer Iv
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of FI934621A0 publication Critical patent/FI934621A0/fi
Publication of FI934621A publication Critical patent/FI934621A/fi
Application granted granted Critical
Publication of FI103890B publication Critical patent/FI103890B/fi
Publication of FI103890B1 publication Critical patent/FI103890B1/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
FI934621A 1992-10-22 1993-10-20 Menetelmä terapeuttisesti käyttökelpoisten pyratsolo[4,3-c]pyridiinien valmistamiseksi FI103890B1 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/964,690 US5264576A (en) 1992-10-22 1992-10-22 Pyrazolo[4,3-c]pyridines which are intermediates
US96469092 1992-10-22

Publications (4)

Publication Number Publication Date
FI934621A0 FI934621A0 (fi) 1993-10-20
FI934621A FI934621A (fi) 1994-04-23
FI103890B FI103890B (fi) 1999-10-15
FI103890B1 true FI103890B1 (fi) 1999-10-15

Family

ID=25508857

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934621A FI103890B1 (fi) 1992-10-22 1993-10-20 Menetelmä terapeuttisesti käyttökelpoisten pyratsolo[4,3-c]pyridiinien valmistamiseksi

Country Status (18)

Country Link
US (4) US5264576A (fi)
EP (1) EP0594001B1 (fi)
JP (1) JP2656211B2 (fi)
KR (1) KR100295026B1 (fi)
CN (1) CN1049658C (fi)
AT (1) ATE195522T1 (fi)
AU (1) AU671305B2 (fi)
CA (1) CA2108941A1 (fi)
DE (1) DE69329231T2 (fi)
DK (1) DK0594001T3 (fi)
ES (1) ES2152237T3 (fi)
FI (1) FI103890B1 (fi)
GR (1) GR3034819T3 (fi)
MX (1) MX9306552A (fi)
NO (1) NO300374B1 (fi)
NZ (1) NZ250003A (fi)
PT (1) PT594001E (fi)
TW (1) TW252114B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300498A (en) * 1993-06-04 1994-04-05 Hoechst-Roussel Pharmaceuticals Incorporated 6-piperazinyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acids, esters, amides and related compounds
US5618824A (en) * 1994-03-09 1997-04-08 Merrell Pharmaceuticals Inc. Treatment of obsessive-compulsive disorders with 5-HT2 antagonists
US5565413A (en) * 1994-12-06 1996-10-15 Zeneca Limited Substituted pyridyl phenyl ketone herbicides
WO2002014317A2 (en) * 2000-08-14 2002-02-21 Ortho Mcneil Pharmaceutical, Inc. Substituted pyrazoles
US20070117785A1 (en) * 2000-08-14 2007-05-24 Butler Christopher R Substituted pyrazoles and methods of treatment with substituted pyrazoles
JP5140225B2 (ja) 2000-08-14 2013-02-06 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 置換ピラゾール
US7332494B2 (en) 2000-08-14 2008-02-19 Janssen Pharmaceutica, N.V. Method for treating allergies using substituted pyrazoles
AU2001286454B2 (en) 2000-08-14 2006-09-14 Ortho-Mcneil Pharmaceutical, Inc. Substituted pyrazoles
US20050101587A9 (en) * 2000-08-14 2005-05-12 Butler Christopher R. Method for treating allergies using substituted pyrazoles
AU2001288714A1 (en) 2000-09-06 2002-03-22 Ortho-Mcneil Pharmaceutical, Inc. A method for treating allergies
WO2003101968A1 (fr) * 2002-05-31 2003-12-11 Eisai Co., Ltd. Compose de pyrazole et composition medicinale le contenant
EP2328895B1 (en) * 2008-09-16 2013-03-27 Proximagen Limited Pyrazolo[4,3-c]pyridine compounds and their use as inhibitors of SSAO
CN102558174B (zh) * 2011-08-23 2014-03-19 天津市斯芬克司药物研发有限公司 一种全新吡唑并[4,3-c]吡啶化合物的发明及其合成方法
CA2871388A1 (en) 2012-06-27 2014-01-03 F. Hoffmann-La Roche Ag 5-azaindazole compounds and methods of use

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3994890A (en) * 1974-01-31 1976-11-30 Chugai Seiyaku Kabushiki Kaisha 1-Aminoalkyl, 3-phenyl indazoles
JPS5944314B2 (ja) * 1975-01-15 1984-10-29 中外製薬株式会社 インダゾ−ル誘導体の製法
JPS5936627B2 (ja) * 1975-07-25 1984-09-05 中外製薬株式会社 インダゾ−ル誘導体の製法
DK27383A (da) * 1982-02-17 1983-08-18 Lepetit Spa Fremgangsmaade til fremstilling af pyrazol(4,3-c)pyridiner
JPH0615542B2 (ja) * 1986-07-22 1994-03-02 吉富製薬株式会社 ピラゾロピリジン化合物
EP0338087A4 (en) * 1987-10-13 1991-07-24 Yoshitomi Pharmaceutical Industries, Ltd. Fused pyrazole compounds, process for their preparation, and their medicinal use
DK181190D0 (da) * 1990-07-30 1990-07-30 Lundbeck & Co As H 3-aryl-indol- eller 3-aryl-indazolderivater
EP0494774A1 (en) * 1991-01-11 1992-07-15 MERCK SHARP & DOHME LTD. Indazole-substituted fivemembered heteroaromatic compounds
GB9216783D0 (en) * 1992-08-07 1992-09-23 Ici Plc Heterocyclic derivatives
US5300478A (en) * 1993-01-28 1994-04-05 Zeneca Limited Substituted fused pyrazolo compounds

Also Published As

Publication number Publication date
EP0594001B1 (en) 2000-08-16
ES2152237T3 (es) 2001-02-01
CN1099033A (zh) 1995-02-22
CA2108941A1 (en) 1994-04-23
NO933784D0 (no) 1993-10-21
US5380847A (en) 1995-01-10
US5428169A (en) 1995-06-27
EP0594001A1 (en) 1994-04-27
AU671305B2 (en) 1996-08-22
DK0594001T3 (da) 2000-10-30
GR3034819T3 (en) 2001-02-28
ATE195522T1 (de) 2000-09-15
FI103890B (fi) 1999-10-15
NO300374B1 (no) 1997-05-20
CN1049658C (zh) 2000-02-23
KR100295026B1 (ko) 2001-09-17
PT594001E (pt) 2001-01-31
DE69329231T2 (de) 2001-03-29
FI934621A0 (fi) 1993-10-20
US5264576A (en) 1993-11-23
KR940009185A (ko) 1994-05-20
MX9306552A (es) 1994-06-30
JPH06192257A (ja) 1994-07-12
TW252114B (fi) 1995-07-21
DE69329231D1 (de) 2000-09-21
NZ250003A (en) 1996-03-26
NO933784L (no) 1994-04-25
US5296491A (en) 1994-03-22
JP2656211B2 (ja) 1997-09-24
AU4912893A (en) 1994-05-05
FI934621A (fi) 1994-04-23

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Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: HOECHST MARION ROUSSEL, INC.