FI103887B1 - Menetelmä terapeuttisesti käyttökelpoisten imidatsolyylimetyyli-pyridiinien valmistamiseksi - Google Patents
Menetelmä terapeuttisesti käyttökelpoisten imidatsolyylimetyyli-pyridiinien valmistamiseksiInfo
- Publication number
- FI103887B1 FI103887B1 FI924233A FI924233A FI103887B1 FI 103887 B1 FI103887 B1 FI 103887B1 FI 924233 A FI924233 A FI 924233A FI 924233 A FI924233 A FI 924233A FI 103887 B1 FI103887 B1 FI 103887B1
- Authority
- FI
- Finland
- Prior art keywords
- carbon atoms
- alkyl
- imidazolylmethyl
- pyridines
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Luminescent Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4131584A DE4131584A1 (de) | 1991-09-23 | 1991-09-23 | Imidazolylmethyl-pyridine, ihre herstellung und anwendung als pharmazeutika |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI924233A0 FI924233A0 (fi) | 1992-09-21 |
| FI924233A FI924233A (fi) | 1993-03-24 |
| FI103887B FI103887B (fi) | 1999-10-15 |
| FI103887B1 true FI103887B1 (fi) | 1999-10-15 |
Family
ID=6441240
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI924233A FI103887B1 (fi) | 1991-09-23 | 1992-09-21 | Menetelmä terapeuttisesti käyttökelpoisten imidatsolyylimetyyli-pyridiinien valmistamiseksi |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0534904B1 (fi) |
| JP (1) | JP2568356B2 (fi) |
| KR (1) | KR100254085B1 (fi) |
| AT (1) | ATE144509T1 (fi) |
| AU (1) | AU650569B2 (fi) |
| CA (1) | CA2078700C (fi) |
| CZ (1) | CZ281675B6 (fi) |
| DE (2) | DE4131584A1 (fi) |
| DK (1) | DK0534904T3 (fi) |
| ES (1) | ES2092666T3 (fi) |
| FI (1) | FI103887B1 (fi) |
| GR (1) | GR3021444T3 (fi) |
| HU (2) | HUT61993A (fi) |
| IL (1) | IL103229A (fi) |
| MX (1) | MX9205365A (fi) |
| MY (1) | MY110450A (fi) |
| NO (1) | NO301162B1 (fi) |
| NZ (1) | NZ244420A (fi) |
| RO (1) | RO109337B1 (fi) |
| RU (1) | RU2058312C1 (fi) |
| SG (1) | SG43079A1 (fi) |
| SK (1) | SK279224B6 (fi) |
| TW (1) | TW222630B (fi) |
| ZA (1) | ZA927279B (fi) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10165349A (ja) * | 1996-12-06 | 1998-06-23 | Matsushita Electric Ind Co Ltd | 食器洗浄機 |
| DE10000161A1 (de) * | 2000-01-06 | 2001-07-19 | Boehringer Ingelheim Pharma | Verfahren zur Identifikation eines Proteaseinhibitors |
| GB0009037D0 (en) * | 2000-04-13 | 2000-05-31 | Novartis Ag | Organic compounds |
| EP1919477B1 (en) * | 2005-07-29 | 2012-07-11 | Vanda Pharmaceuticals Inc. | Use of [2-(2-methylimidazol-1-yl)methyl]pyridine for treating sleep disorders |
| AU2007214487A1 (en) * | 2006-02-13 | 2007-08-23 | Vanda Pharmaceuticals, Inc. | Stable dosage formulations of imidazolylalkyl-pyridines |
| WO2009097416A1 (en) * | 2008-01-29 | 2009-08-06 | Vanda Pharmaceuticals, Inc. | Imidazolylalkyl- pyridines as dbh inhibitors |
| CA2740873C (en) | 2008-10-17 | 2019-09-10 | Wisconsin Alumni Research Foundation | Method of making biologically active alpha-beta peptides |
| WO2012052540A1 (en) * | 2010-10-21 | 2012-04-26 | Universitaet Des Saarlandes | Selective cyp11b1 inhibitors for the treatment of cortisol dependent diseases |
| JP2020520952A (ja) * | 2017-05-22 | 2020-07-16 | トーリー パインズ インスティテュート フォー モレキュラー スタディーズＴｏｒｒｅｙ Ｐｉｎｅｓ Ｉｎｓｔｉｔｕｔｅ Ｆｏｒ Ｍｏｌｅｃｕｌａｒ Ｓｔｕｄｉｅｓ | 組成物、使用方法、及び治療方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2862340D1 (en) * | 1978-02-01 | 1983-11-24 | Wellcome Found | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof |
| GB2028317B (en) * | 1978-08-15 | 1982-11-10 | Pfizer Ltd | 2-(imidazol-1-ylmethyl)-pyridine and -quinoline thromboxane synthetase inhibitors |
| US4634711A (en) * | 1985-08-02 | 1987-01-06 | Smithkline Beckman Corporation | Pyridylalkyl imidazole-2-thiols |
| DE3811574A1 (de) * | 1988-03-31 | 1989-10-19 | Schering Ag | N-substituierte imidazole, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
-
1991
- 1991-09-23 DE DE4131584A patent/DE4131584A1/de not_active Withdrawn
-
1992
- 1992-09-09 HU HU9202886A patent/HUT61993A/hu unknown
- 1992-09-18 MY MYPI92001673A patent/MY110450A/en unknown
- 1992-09-21 ES ES92810719T patent/ES2092666T3/es not_active Expired - Lifetime
- 1992-09-21 IL IL10322992A patent/IL103229A/en not_active IP Right Cessation
- 1992-09-21 CA CA002078700A patent/CA2078700C/en not_active Expired - Fee Related
- 1992-09-21 CZ CS922896A patent/CZ281675B6/cs not_active IP Right Cessation
- 1992-09-21 SK SK2896-92A patent/SK279224B6/sk not_active IP Right Cessation
- 1992-09-21 AU AU25226/92A patent/AU650569B2/en not_active Ceased
- 1992-09-21 SG SG1996003366A patent/SG43079A1/en unknown
- 1992-09-21 FI FI924233A patent/FI103887B1/fi not_active IP Right Cessation
- 1992-09-21 DK DK92810719.2T patent/DK0534904T3/da active
- 1992-09-21 AT AT92810719T patent/ATE144509T1/de active
- 1992-09-21 NO NO923653A patent/NO301162B1/no not_active IP Right Cessation
- 1992-09-21 NZ NZ244420A patent/NZ244420A/xx not_active IP Right Cessation
- 1992-09-21 EP EP92810719A patent/EP0534904B1/de not_active Expired - Lifetime
- 1992-09-21 DE DE59207425T patent/DE59207425D1/de not_active Expired - Lifetime
- 1992-09-22 RU SU925052552A patent/RU2058312C1/ru active
- 1992-09-22 MX MX9205365A patent/MX9205365A/es unknown
- 1992-09-22 JP JP4252692A patent/JP2568356B2/ja not_active Expired - Fee Related
- 1992-09-22 RO RO92-01218A patent/RO109337B1/ro unknown
- 1992-09-22 KR KR1019920017228A patent/KR100254085B1/ko not_active IP Right Cessation
- 1992-09-23 ZA ZA927279A patent/ZA927279B/xx unknown
- 1992-09-24 TW TW081107550A patent/TW222630B/zh active
-
1995
- 1995-06-13 HU HU95P/P00198P patent/HU211261A9/hu unknown
-
1996
- 1996-10-24 GR GR960402593T patent/GR3021444T3/el unknown
Also Published As
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| EP0239445A3 (en) | 1,2,5,6-tetrahydropyridine-3-carboxaldehyde oxime derivatives, process for their preparation, compositions containing them and their use as medicines | |
| FI103887B (fi) | Menetelmä terapeuttisesti käyttökelpoisten imidatsolyylimetyyli-pyridiinien valmistamiseksi | |
| MX12708A (es) | Derivados de oxima de 1,2,5,6-tetrahidropiridina yprocedimiento para su preparacion | |
| JPS6468356A (en) | Novel 1,2,5,6-tetrahydropyridine-3-carboxaldehydro oxime derivatives, use as drug and composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or assigment of application |
Owner name: NOVARTIS AG |
|
| MM | Patent lapsed |