FI102922B1 - Fluoresenssiin perustuva immunomääritysmenetelmä - Google Patents

Fluoresenssiin perustuva immunomääritysmenetelmä

Info

Publication number
FI102922B1
FI102922B1 FI962686A FI962686A FI102922B1 FI 102922 B1 FI102922 B1 FI 102922B1 FI 962686 A FI962686 A FI 962686A FI 962686 A FI962686 A FI 962686A FI 102922 B1 FI102922 B1 FI 102922B1
Authority
FI
Finland
Prior art keywords
based immunoassay
fluorescence
fluorescence based
analyte
molecules
Prior art date
Application number
FI962686A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI102922B (fi
FI962686A0 (fi
FI962686A (fi
Inventor
Kari Keinaenen
Marja-Leena Laukkanen
Hans Soederlund
Original Assignee
Valtion Teknillinen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valtion Teknillinen filed Critical Valtion Teknillinen
Publication of FI962686A0 publication Critical patent/FI962686A0/fi
Priority to FI962686A priority Critical patent/FI102922B1/fi
Priority to PT97928295T priority patent/PT932830E/pt
Priority to CA002257941A priority patent/CA2257941A1/fr
Priority to US09/202,976 priority patent/US6235535B1/en
Priority to ES97928295T priority patent/ES2181007T3/es
Priority to NZ333472A priority patent/NZ333472A/xx
Priority to AU32647/97A priority patent/AU722353B2/en
Priority to JP50386198A priority patent/JP3436374B2/ja
Priority to PCT/FI1997/000419 priority patent/WO1998000714A1/fr
Priority to DE69716454T priority patent/DE69716454T2/de
Priority to DK97928295T priority patent/DK0932830T3/da
Priority to AT97928295T priority patent/ATE226323T1/de
Priority to EP97928295A priority patent/EP0932830B1/fr
Publication of FI962686A publication Critical patent/FI962686A/fi
Priority to NO986043A priority patent/NO986043L/no
Application granted granted Critical
Publication of FI102922B publication Critical patent/FI102922B/fi
Publication of FI102922B1 publication Critical patent/FI102922B1/fi

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/5436Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/805Optical property
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/819Multifunctional antigen or antibody
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/829Liposomes, e.g. encapsulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Luminescent Compositions (AREA)
  • Steroid Compounds (AREA)
FI962686A 1996-06-28 1996-06-28 Fluoresenssiin perustuva immunomääritysmenetelmä FI102922B1 (fi)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FI962686A FI102922B1 (fi) 1996-06-28 1996-06-28 Fluoresenssiin perustuva immunomääritysmenetelmä
PCT/FI1997/000419 WO1998000714A1 (fr) 1996-06-28 1997-06-30 Dosage par interaction de ligand a transfert d'energie fluorescente sur une couche lipidique
DK97928295T DK0932830T3 (da) 1996-06-28 1997-06-30 Fluorescens-energioverførselsligandvekselvirkningsanalyse på en lipidfilm
US09/202,976 US6235535B1 (en) 1996-06-28 1997-06-30 Fluorescent energy transfer ligand interaction assay on a lipid film
ES97928295T ES2181007T3 (es) 1996-06-28 1997-06-30 Ensayo de interaccion de ligandos con transferencia de energia fluorescente sobre una pelicula lipidica.
NZ333472A NZ333472A (en) 1996-06-28 1997-06-30 Fluorescent energy transfer ligand interaction assay on a lipid film
AU32647/97A AU722353B2 (en) 1996-06-28 1997-06-30 Fluorescent energy transfer ligand interaction assay on a lipid film
JP50386198A JP3436374B2 (ja) 1996-06-28 1997-06-30 脂質皮膜における蛍光エネルギー移動リガンド相互作用検定
PT97928295T PT932830E (pt) 1996-06-28 1997-06-30 Ensaio de transferencia de energia de fluorescencia por interaccao de ligados num filme lipidico
DE69716454T DE69716454T2 (de) 1996-06-28 1997-06-30 Nachweisverfahren mit hilfe von fluoreszent-energietransferliganden auf lipidfilmen
CA002257941A CA2257941A1 (fr) 1996-06-28 1997-06-30 Dosage par interaction de ligand a transfert d'energie fluorescente sur une couche lipidique
AT97928295T ATE226323T1 (de) 1996-06-28 1997-06-30 Nachweisverfahren mit hilfe von fluoreszent- energietransferliganden auf lipidfilmen
EP97928295A EP0932830B1 (fr) 1996-06-28 1997-06-30 Dosage par interaction de ligand a transfert d'energie fluorescente sur une couche lipidique
NO986043A NO986043L (no) 1996-06-28 1998-12-22 Fluorescent energioverf°ringsligand interaksjonsassay pÕ en lipid film

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI962686 1996-06-28
FI962686A FI102922B1 (fi) 1996-06-28 1996-06-28 Fluoresenssiin perustuva immunomääritysmenetelmä

Publications (4)

Publication Number Publication Date
FI962686A0 FI962686A0 (fi) 1996-06-28
FI962686A FI962686A (fi) 1997-12-29
FI102922B FI102922B (fi) 1999-03-15
FI102922B1 true FI102922B1 (fi) 1999-03-15

Family

ID=8546307

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962686A FI102922B1 (fi) 1996-06-28 1996-06-28 Fluoresenssiin perustuva immunomääritysmenetelmä

Country Status (14)

Country Link
US (1) US6235535B1 (fr)
EP (1) EP0932830B1 (fr)
JP (1) JP3436374B2 (fr)
AT (1) ATE226323T1 (fr)
AU (1) AU722353B2 (fr)
CA (1) CA2257941A1 (fr)
DE (1) DE69716454T2 (fr)
DK (1) DK0932830T3 (fr)
ES (1) ES2181007T3 (fr)
FI (1) FI102922B1 (fr)
NO (1) NO986043L (fr)
NZ (1) NZ333472A (fr)
PT (1) PT932830E (fr)
WO (1) WO1998000714A1 (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9801120D0 (en) 1998-01-21 1998-03-18 Secr Defence Detection system
US6297059B1 (en) * 1998-06-22 2001-10-02 The Regents Of The University Of California Triggered optical biosensor
JP2003529319A (ja) * 1999-01-08 2003-10-07 キャロル ディ. ウエイス, HIV−1gp41を標的化する広範に中和する抗体を誘発する方法
US6627396B1 (en) * 1999-10-28 2003-09-30 The Regents Of The University Of California Influenza sensor
US6984494B2 (en) * 2000-08-15 2006-01-10 Genentech, Inc. Analytical method
AT410601B (de) * 2000-12-29 2003-06-25 Hoffmann La Roche Sensor zur lumineszenz-optischen bestimmung eines analyten sowie reagens, das nach dem fret-prinzip arbeitet
JP2004524528A (ja) * 2001-02-14 2004-08-12 ユニバーシティ オブ メリーランド,ボルチモア 放射減衰操作
US20020192721A1 (en) * 2001-03-28 2002-12-19 Engeneos, Inc. Modular molecular clasps and uses thereof
CA2448719A1 (fr) * 2001-06-09 2002-12-19 Glsynthesis Inc. Structures de lipides et utilisations correspondantes
US20030059811A1 (en) * 2001-06-14 2003-03-27 Hakim Djaballah Methods of screening for ligands of target molecules
US6713272B2 (en) * 2001-09-19 2004-03-30 The United States Of America As Represented By The Secretary Of The Navy Attachment of biomolecules to hydrophobic surfaces
WO2004011642A1 (fr) * 2002-03-21 2004-02-05 The Regents Of The University Of California Systeme generique d'ancrage d'une membrane
CA2482827A1 (fr) * 2002-04-30 2003-11-13 University Of Maryland, Baltimore Detection de fluorescence
US20040146959A1 (en) * 2002-09-09 2004-07-29 Graham Ronald J. Fluorescent enzyme assay methods and compositions
JP2005538377A (ja) * 2002-09-11 2005-12-15 シナメム コーポレイション 膜ベースアッセイ
JP4511363B2 (ja) * 2002-11-07 2010-07-28 エラスムス ユニフェルシテイト ロッテルダム 相互作用する分子を検出するためのfretプローブおよび方法
US20040171175A1 (en) * 2003-02-28 2004-09-02 Swanson Basil I. Process for conjugating biomolecules to hydrophobic membrane-incorporated molecules
US8741577B2 (en) * 2003-04-07 2014-06-03 Bio-Rad Laboratories Inc. Surface immobilised multilayer structure of vesicles
EP1687635A2 (fr) * 2003-11-26 2006-08-09 Applera Corporation Micelles renfermant des ligands et utilisation de celles-ci
EP1690089A1 (fr) * 2003-11-26 2006-08-16 Applera Corporation Procedes et compositions d'essai de liaison homogene fluorogene
WO2005054859A1 (fr) * 2003-12-01 2005-06-16 Fujirebio Inc. Biocapteur optique
EP1704257A2 (fr) * 2004-01-16 2006-09-27 Applera Corporation Essais fluorogeniques pour kinase et substrats
US20060035302A1 (en) * 2004-06-21 2006-02-16 Applera Corporation Kinase substrates with multiple phosphorylation sites
US7399607B2 (en) * 2004-09-22 2008-07-15 Allergan, Inc. Fluorescence polarization assays for determining clostridial toxin activity
US20060121553A1 (en) * 2004-10-29 2006-06-08 Applera Corporation Fluorogenic enzyme assay methods, kits and compositions using charge-balancers
WO2006074074A2 (fr) * 2004-12-30 2006-07-13 Applera Corporation Compositions, procedes et trousses pour des dosages enzymatiques en temps reel a l'aide de molecules chargees
US20060240571A1 (en) * 2005-04-20 2006-10-26 Zahner Joseph E Biosensors and methods for detecting agents based upon time resolved luminescent resonance energy transfer
US7923240B2 (en) * 2006-03-31 2011-04-12 Intel Corporation Photo-activated field effect transistor for bioanalyte detection
US20090270269A1 (en) * 2008-04-28 2009-10-29 Ashok Kumar Nano-scale fluoro-biosensors exhibiting a low false alarm rate for rapid detection of biological contaminants
CN102725637B (zh) 2010-01-25 2015-02-25 松下健康医疗控股株式会社 在自组装单层上固定a蛋白的方法
CN102918064B (zh) 2010-08-30 2015-03-11 松下健康医疗控股株式会社 在自组装单层上固定链霉亲和素的方法
CN103124786A (zh) 2010-10-19 2013-05-29 松下电器产业株式会社 将葡萄糖氧化酶固定在自组装膜上的方法
WO2012168988A1 (fr) * 2011-06-10 2012-12-13 パナソニック株式会社 Procédé de fixation d'anticorps à une monocouche auto-assemblée

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254096A (en) * 1979-10-04 1981-03-03 Bio-Rad Laboratories, Inc. Reagent combination for solid phase immunofluorescent assay
US4598051A (en) * 1980-03-12 1986-07-01 The Regents Of The University Of California Liposome conjugates and diagnostic methods therewith
US4605630A (en) * 1983-07-27 1986-08-12 Cooper Lipotech Inc. Large-liposome agglutination reagent and method
US5011771A (en) * 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
US4971916A (en) * 1987-07-29 1990-11-20 Abbott Laboratories Liposome based homogeneous immunoassay for diagnostic tests
GB8807488D0 (en) 1988-03-29 1988-05-05 Ares Serono Res & Dev Ltd Method of assay
US5094819A (en) * 1989-06-16 1992-03-10 Washington Research Foundation Fluorescence-based optical sensor and method for detection of lipid-soluble analytes
DE59005928D1 (de) 1989-11-21 1994-07-07 Bayer Ag Optischer Biosensor.
WO1993010226A1 (fr) * 1991-11-19 1993-05-27 North Carolina State University Dosage de diagnostic immunologique au moyen de liposomes portant des marqueurs sur leur surface exterieure
DE4319037A1 (de) 1993-06-08 1994-12-15 Bayer Ag Beschichtete Träger, Verfahren zu ihrer Herstellung und ihre Verwendung zur Immobilisierung von Biomolekülen an Oberlfächen von Festkörpern
WO1995008637A1 (fr) 1993-09-21 1995-03-30 Washington State University Research Foundation Dosage immunologique comportant un recepteur de canal d'ions conjugue a un ligand immobilise dans un film de lipides
US5650334A (en) * 1995-08-31 1997-07-22 First Medical, Inc. Fluorescent labelling compositions and methods for their use
AU710425B2 (en) * 1995-12-18 1999-09-23 Washington University Method for nucleic acid analysis using fluorescence resonance energy transfer
US5780319A (en) * 1996-04-19 1998-07-14 Pasteur Sanofi Diagnostics Immunoassays to detect antiphospholipid antibodies

Also Published As

Publication number Publication date
CA2257941A1 (fr) 1998-01-08
WO1998000714A1 (fr) 1998-01-08
FI102922B (fi) 1999-03-15
DE69716454T2 (de) 2003-08-14
EP0932830B1 (fr) 2002-10-16
NO986043D0 (no) 1998-12-22
FI962686A0 (fi) 1996-06-28
ATE226323T1 (de) 2002-11-15
US6235535B1 (en) 2001-05-22
DK0932830T3 (da) 2003-02-17
JP3436374B2 (ja) 2003-08-11
NO986043L (no) 1998-12-22
AU722353B2 (en) 2000-07-27
EP0932830A1 (fr) 1999-08-04
FI962686A (fi) 1997-12-29
DE69716454D1 (de) 2002-11-21
PT932830E (pt) 2003-02-28
JP2000515965A (ja) 2000-11-28
NZ333472A (en) 2000-01-28
AU3264797A (en) 1998-01-21
ES2181007T3 (es) 2003-02-16

Similar Documents

Publication Publication Date Title
FI102922B1 (fi) Fluoresenssiin perustuva immunomääritysmenetelmä
DK0645015T3 (da) Forbedringer ved eller i forbindelse med analytpåvisning.
TR200000565T2 (tr) Biyolojik örneklerdeki analiz bileşenlerinin hızlı analizi için yöntem
DK1111386T3 (da) Teststrimmel til bestemmelse af en analyt i en flydende pröve
ATE425266T1 (de) Aptamer-nanopartikelkonjugate und verwendungsverfahren zur detektion von zielanalyten
ATE393914T1 (de) Nachweis von biomolekülen unter verwendung poröser biosensoren und raman-spektroskopie
DE60317422D1 (de) Mediator-stabilisierende Verbindung und Methoden zur Verwendung zur Detektion elektrochemischer Analyte
GB9804083D0 (en) Immunoassays
ATE297950T1 (de) Testverfahren und reagenzien zur quantifizierung von hbnp
TR200000921T2 (tr) Bir sıvı mandıra ürünü içindeki analitlerin saptanması için tahlil cihazı
DK1513878T3 (da) Sammensætninger og fremgangsmåder til analyse af Apo B48 og Apo B100
TR199901569T2 (xx) T�berk�lozun te�hisi i�in bile�ikler ve y�ntemler.
ATE406578T1 (de) Candida-nachweis
DE50115064D1 (de) Sensor zur lumineszenz-optischen bestimmung eines analyten
DE69928507D1 (de) Festphasenverfahren und testsatz zur antigen- und antikörperprüfung in der blutgruppen-serologie
DE60130919D1 (de) Durchflussvorrichtung, diagnostischer kit diese enthaltend und gebrauch für den nachweis von analyten in einer probe
ATE330225T1 (de) Verfahren und testkit zum nachweis von analyten in einer probe
ATE431931T1 (de) Erstellung von digitalaufnahmen einzelner radialer immundiffusionstests
DE50203136D1 (de) Verfahren zum Nachweis von Analyten in Proben mittels Analysenelementen
EP2105741A3 (fr) Utilisation d'un virus exprimant un groupe caractéristique de liaison pour mesurer des analytes dans un échantillon
DE59910326D1 (de) Verwendung derivatisierter Reagenzien in Chemilumineszenz- und Elektrochemilumineszenz-Nachweisverfahren
ATE285075T1 (de) Detektion und quantifikation von vancomycin in den biologischen flüssigkeiten
Lv et al. A microchip with air sampling and chemiluminescence detection for analyzing iron in nature water and in whole blood
ATE305980T1 (de) Verwendung von abfangsonden beim nachweis von nukleinsäuren
DK1423708T3 (da) Sammensætninger og fremgangsmåder til bestemmelser af AA4RP

Legal Events

Date Code Title Description
MA Patent expired