FI101575B1 - Menetelmä reagenssin pitoisuuden mittaamiseksi reaktioseoksessa - Google Patents

Menetelmä reagenssin pitoisuuden mittaamiseksi reaktioseoksessa

Info

Publication number
FI101575B1
FI101575B1 FI922478A FI922478A FI101575B1 FI 101575 B1 FI101575 B1 FI 101575B1 FI 922478 A FI922478 A FI 922478A FI 922478 A FI922478 A FI 922478A FI 101575 B1 FI101575 B1 FI 101575B1
Authority
FI
Finland
Prior art keywords
reagent
concentration
reaction mixture
dye
measuring
Prior art date
Application number
FI922478A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI922478A0 (fi
FI922478A7 (fi
FI101575B (fi
Inventor
Richard Cornelius Driscoll
Timothy J Fischer
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI922478A0 publication Critical patent/FI922478A0/fi
Publication of FI922478A7 publication Critical patent/FI922478A7/fi
Application granted granted Critical
Publication of FI101575B1 publication Critical patent/FI101575B1/fi
Publication of FI101575B publication Critical patent/FI101575B/fi

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Plasma & Fusion (AREA)
  • Cell Biology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
FI922478A 1989-12-01 1992-05-29 Menetelmä reagenssin pitoisuuden mittaamiseksi reaktioseoksessa FI101575B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/443,953 US5068181A (en) 1989-12-01 1989-12-01 Method of monitoring reagent delivery in a scanning spectrophotometer
US44395389 1989-12-01
US9007068 1990-12-03
PCT/US1990/007068 WO1991008461A1 (en) 1989-12-01 1990-12-03 Method of monitoring reagent delivery in a scanning spectrophotometer

Publications (4)

Publication Number Publication Date
FI922478A0 FI922478A0 (fi) 1992-05-29
FI922478A7 FI922478A7 (fi) 1992-05-29
FI101575B1 true FI101575B1 (fi) 1998-07-15
FI101575B FI101575B (fi) 1998-07-15

Family

ID=23762872

Family Applications (1)

Application Number Title Priority Date Filing Date
FI922478A FI101575B (fi) 1989-12-01 1992-05-29 Menetelmä reagenssin pitoisuuden mittaamiseksi reaktioseoksessa

Country Status (14)

Country Link
US (1) US5068181A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0502983B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP2902108B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100210736B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE142018T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (2) AU655577B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2069887C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE69028312T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0502983T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2095310T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI101575B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3021261T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE75698B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1991008461A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (28)

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US5646046A (en) * 1989-12-01 1997-07-08 Akzo Nobel N.V. Method and instrument for automatically performing analysis relating to thrombosis and hemostasis
ES2121011T3 (es) * 1991-02-15 1998-11-16 Formulogics Inc Determinacion de contaminantes.
US5580744A (en) * 1992-04-27 1996-12-03 Avocet Medical, Inc. Test article and method for performing blood coagulation assays
US5344036A (en) * 1992-06-04 1994-09-06 Akzo N.V. Container system
US5447838A (en) * 1992-08-05 1995-09-05 Hybritech Incorporated Protein-dye conjugate for confirmation of correct dilution of calibrators
US5919707A (en) * 1994-12-22 1999-07-06 Nalco Chemical Company Monitoring of rolling oil emulsions
US6830934B1 (en) * 1999-06-15 2004-12-14 Lifescan, Inc. Microdroplet dispensing for a medical diagnostic device
US6521182B1 (en) * 1998-07-20 2003-02-18 Lifescan, Inc. Fluidic device for medical diagnostics
DE10257716B4 (de) 2002-12-11 2005-12-29 Institut für Textilchemie der Deutschen Institute für Textil- und Faserforschung Stuttgart Optischer Sensor zur Bestimmung von Farbstoffkonzentrationen in flüssigen Medien und Verfahren zu dessen Betrieb
US7283245B2 (en) * 2004-01-20 2007-10-16 General Electric Company Handheld device with a disposable element for chemical analysis of multiple analytes
US20060001551A1 (en) * 2004-06-30 2006-01-05 Ulrich Kraft Analyte monitoring system with wireless alarm
US8343074B2 (en) 2004-06-30 2013-01-01 Lifescan Scotland Limited Fluid handling devices
US20060002817A1 (en) * 2004-06-30 2006-01-05 Sebastian Bohm Flow modulation devices
US20060000709A1 (en) * 2004-06-30 2006-01-05 Sebastian Bohm Methods for modulation of flow in a flow pathway
US7929121B2 (en) * 2008-03-21 2011-04-19 Abbott Point Of Care, Inc. Method and apparatus for detecting and counting platelets individually and in aggregate clumps
EP2554987B1 (en) 2008-03-21 2014-04-16 Abbott Point Of Care, Inc. Method and apparatus for determining red blood cell indices of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells
CN102016686B (zh) * 2008-03-21 2015-03-25 艾博特健康公司 确定对生物样本成像的成像装置的焦点位置的方法和设备
CA2718992C (en) 2008-03-21 2013-04-30 Abbott Point Of Care, Inc. Method and apparatus for determining the hematocrit of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells
US8081303B2 (en) * 2008-03-21 2011-12-20 Abbott Point Of Care, Inc. Method and apparatus for analyzing individual cells or particulates using fluorescent quenching and/or bleaching
CA2720068C (en) * 2008-04-02 2013-11-19 Abbott Point Of Care, Inc. Virtual separation of bound and free label in a ligand assay for performing immunoassays of biological fluids, including whole blood
ES2597927T3 (es) * 2008-04-09 2017-01-24 Abbott Point Of Care, Inc. Procedimiento para medir el área de una muestra dispuesta dentro de una cámara de análisis
JP5539314B2 (ja) * 2008-04-09 2014-07-02 アボット ポイント オブ ケア インコーポレイテッド 薄厚チャンバに含まれる薄膜状体液試料中の極めて低レベルの分析物を検出する方法
US20100255605A1 (en) * 2009-04-02 2010-10-07 Abbott Point Of Care, Inc. Method and device for transferring biologic fluid samples
EP2430446A4 (en) * 2009-05-11 2012-12-05 Nexus Dx Inc METHOD AND COMPOSITIONS FOR DETECTING ANALYTES
ES2438841T3 (es) * 2009-12-31 2014-01-20 Abbott Point Of Care, Inc. Método y aparato para determinar el volumen celular medio de los glóbulos rojos en la sangre
WO2011116305A1 (en) 2010-03-18 2011-09-22 Abbott Point Of Care, Inc. Method and apparatus for optically determining at least one hemoglobin related parameter of a whole blood sample
CN102128796B (zh) * 2010-12-07 2012-07-25 桂林理工大学 一种测定硫酸庆大霉素的方法
US9476871B2 (en) 2012-05-02 2016-10-25 Diatech Oncology Llc System and method for automated determination of the relative effectiveness of anti-cancer drug candidates

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
US3059524A (en) * 1958-06-04 1962-10-23 Grassmann Wolfgang Method and apparatus for the continuous colorimetric determination of the individualcomponents of a mixture
US4204839A (en) * 1978-08-09 1980-05-27 Eastman Kodak Company Fluorimetric analysis method for bilirubin
US4274744A (en) * 1978-11-21 1981-06-23 Medico Electronic, Inc. Direct reading digital colorimeter
US4329149A (en) * 1980-03-06 1982-05-11 Hach Chemical Company Method for spectrophotometric compensation for colorimetric reagent variation
DE3019612A1 (de) * 1980-05-22 1981-11-26 Boehringer Mannheim Gmbh, 6800 Mannheim Stabilisiertes thrombinpraeparat
US4506626A (en) * 1981-11-02 1985-03-26 Schurman Richard H Apparatus for controlling the proportions of a fluid
US4543335A (en) * 1982-12-20 1985-09-24 Miles Laboratories, Inc. Device and method for the quantitative determination of heparin in mammalian blood plasma
US4849340A (en) * 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
US4911549A (en) * 1988-04-05 1990-03-27 Baxter International Inc. Heparin monitoring system and methodology

Also Published As

Publication number Publication date
US5068181A (en) 1991-11-26
AU6951291A (en) 1991-06-26
EP0502983B1 (en) 1996-08-28
ATE142018T1 (de) 1996-09-15
JP2902108B2 (ja) 1999-06-07
EP0502983A4 (en) 1993-05-05
EP0502983A1 (en) 1992-09-16
IE75698B1 (en) 1997-09-10
FI922478A0 (fi) 1992-05-29
FI922478A7 (fi) 1992-05-29
CA2069887C (en) 2004-02-10
WO1991008461A1 (en) 1991-06-13
IE904276A1 (en) 1991-06-05
FI101575B (fi) 1998-07-15
JPH05502723A (ja) 1993-05-13
CA2069887A1 (en) 1991-06-02
KR920704118A (ko) 1992-12-19
AU655577B2 (en) 1995-01-05
DE69028312D1 (de) 1996-10-02
KR100210736B1 (ko) 1999-07-15
AU1628795A (en) 1995-06-29
DE69028312T2 (de) 1997-01-16
ES2095310T3 (es) 1997-02-16
GR3021261T3 (en) 1997-01-31
DK0502983T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1997-01-20

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Legal Events

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MA Patent expired