ES8801912A1 - Procedimiento para la obtencion de benzopiranos sustituidos. - Google Patents

Procedimiento para la obtencion de benzopiranos sustituidos.

Info

Publication number
ES8801912A1
ES8801912A1 ES556864A ES556864A ES8801912A1 ES 8801912 A1 ES8801912 A1 ES 8801912A1 ES 556864 A ES556864 A ES 556864A ES 556864 A ES556864 A ES 556864A ES 8801912 A1 ES8801912 A1 ES 8801912A1
Authority
ES
Spain
Prior art keywords
medicines
preparation
benzopyrans
substituted
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES556864A
Other languages
English (en)
Other versions
ES556864A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES8801912A1 publication Critical patent/ES8801912A1/es
Publication of ES556864A0 publication Critical patent/ES556864A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Glass Compositions (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
  • Dental Preparations (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE BENZOPIRANOS SUSTITUIDOS, DE FORMULA GENERAL (I), Y SUS SALES DE ADICION FARMACEUTICAMENTE INOCUAS. CONSISTE EN HACER REACCIONAR COMPUESTOS DE FORMULA GENERAL (II) CON LAS AMINAS DE FORMULA GENERAL (III), EN PRESENCIA DE UN AGENTE ACEPTOR DE ACIDO, SIENDO R1 Y R2 IGUALES O DIFERENTES Y SIGNIFICAN HIDROGENO, ALQUILO O CICLOALQUILO; A REPRESENTA UN ENLACE SENCILLO O UN ENLACE DOBLE; R3, R4, R5 Y R6 SON IGUALES O DIFERENTES Y SIGNIFICAN HIDROGENO, HIDROXI, HALOGENO O ALQUILO; R7, R8, R9, R10 Y R11 SON IGUALES O DIFERENTES Y SIGNIFICAN HIDROGENO O ALQUILO; X SIGNIFICA UN ENLACE SENCILLO; Y R17 SIGNIFICA HIDROGENO O ALQUILO HASTA 6 ATOMOS DE CARBONO. DE APLICACION COMO AGENTES INFLUENCIADORES DEL SISTEMA CIRCULATORIO.
ES556864A 1984-03-31 1986-07-01 Procedimiento para la obtencion de benzopiranos sustituidos. Expired ES8801912A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843411993 DE3411993A1 (de) 1984-03-31 1984-03-31 Substituierte benzopyrane, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimittel

Publications (2)

Publication Number Publication Date
ES8801912A1 true ES8801912A1 (es) 1987-08-01
ES556864A0 ES556864A0 (es) 1987-08-01

Family

ID=6232185

Family Applications (2)

Application Number Title Priority Date Filing Date
ES541583A Expired ES8703448A1 (es) 1984-03-31 1985-03-26 Procedimiento para la obtencion de neuropiranos sustituibles.
ES556864A Expired ES8801912A1 (es) 1984-03-31 1986-07-01 Procedimiento para la obtencion de benzopiranos sustituidos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES541583A Expired ES8703448A1 (es) 1984-03-31 1985-03-26 Procedimiento para la obtencion de neuropiranos sustituibles.

Country Status (17)

Country Link
US (1) US4659737A (es)
EP (1) EP0157267B1 (es)
JP (1) JPS60224685A (es)
KR (1) KR850006194A (es)
AT (1) ATE38836T1 (es)
AU (1) AU4059485A (es)
DE (2) DE3411993A1 (es)
DK (1) DK144685A (es)
ES (2) ES8703448A1 (es)
FI (1) FI851261L (es)
GR (1) GR850799B (es)
HU (1) HUT38097A (es)
IL (1) IL74745A0 (es)
NO (1) NO851010L (es)
NZ (1) NZ211617A (es)
PT (1) PT80191B (es)
ZA (1) ZA852391B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4918092A (en) * 1983-12-21 1990-04-17 Merck Frosst Canada, Inc. Leukotriene antagonists
ES2044970T3 (es) * 1986-06-26 1994-01-16 Ciba Geigy Ag Procedimiento para la obtencion de compuestos hidrogenados del acido 1-benzooxacicloalquil-piridincarboxilico.
FR2618437B1 (fr) * 1987-07-23 1989-11-17 Rhone Poulenc Sante Nouveaux derives du benzopyranne, leur preparation et les medicaments qui les contiennent
DE3737195A1 (de) * 1987-11-03 1989-05-18 Bayer Ag Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5140039A (en) * 1988-01-15 1992-08-18 Abbott Laboratories Aminomethyl-thiochroman compounds
US5185364A (en) * 1988-01-15 1993-02-09 Abbott Laboratories Aminomethyl-chroman and -thiochroman compounds
EP0325964A1 (en) * 1988-01-15 1989-08-02 Abbott Laboratories Aminomethyl-chroman and -thiochroman compounds
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
US5264458A (en) * 1989-11-02 1993-11-23 Bayer Aktiengesellschaft Antithrombotic iso- and heterocyclic phenylsulphonamides
WO1992008712A1 (en) * 1990-11-08 1992-05-29 Yamanouchi Pharmaceutical Co., Ltd. Flavane derivative or salt thereof and novel production process
US5837702A (en) * 1993-10-07 1998-11-17 Bristol-Myers Squibb Co. 4-arylamino-benzopyran and related compounds
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
GB9801392D0 (en) * 1998-01-22 1998-03-18 Smithkline Beecham Plc Novel compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH648030A5 (de) * 1980-12-15 1985-02-28 Sandoz Ag Benzopyran-allylaminderivate, verfahren zu ihrer herstellung und ihre verwendung.
DE3300004A1 (de) * 1983-01-03 1984-07-12 Bayer Ag, 5090 Leverkusen Substituierte 4-aminomethylenchromane bzw. -chromene, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
AU4059485A (en) 1985-10-03
IL74745A0 (en) 1985-06-30
JPS60224685A (ja) 1985-11-09
HUT38097A (en) 1986-04-28
DE3411993A1 (de) 1985-10-10
ATE38836T1 (de) 1988-12-15
PT80191A (en) 1985-04-01
FI851261A0 (fi) 1985-03-28
ES8703448A1 (es) 1987-02-16
EP0157267A2 (de) 1985-10-09
EP0157267B1 (de) 1988-11-23
NO851010L (no) 1985-10-01
DK144685D0 (da) 1985-03-29
ZA852391B (en) 1985-11-27
EP0157267A3 (en) 1986-09-03
ES556864A0 (es) 1987-08-01
KR850006194A (ko) 1985-10-02
DK144685A (da) 1985-10-01
ES541583A0 (es) 1987-02-16
GR850799B (es) 1985-11-25
US4659737A (en) 1987-04-21
NZ211617A (en) 1987-10-30
FI851261L (fi) 1985-10-01
DE3566404D1 (en) 1988-12-29
PT80191B (en) 1987-03-18

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