ES8608887A1 - Procedimiento para la obtencion de preparados combinados antihipertensores y antianginicos a base de dihidropiridina y bloquear beta. - Google Patents
Procedimiento para la obtencion de preparados combinados antihipertensores y antianginicos a base de dihidropiridina y bloquear beta.Info
- Publication number
- ES8608887A1 ES8608887A1 ES545522A ES545522A ES8608887A1 ES 8608887 A1 ES8608887 A1 ES 8608887A1 ES 545522 A ES545522 A ES 545522A ES 545522 A ES545522 A ES 545522A ES 8608887 A1 ES8608887 A1 ES 8608887A1
- Authority
- ES
- Spain
- Prior art keywords
- mixture
- drug
- application
- manufacturing process
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
METODO DE PREPARACION DE COMPOSICIONES A BASE DE DIHIDROPIRIDINA Y BLOQUEADOR BETA, QUE TIENEN APLICACIONES FARMACOLOGICAS POR SU EFECTO ANTIHIPERTENSOR Y ANTIANGINICO. COMPRENDE LA REACCION DE UN ACIDO CETOCARBOXILICO DE FORMULA (I) O (II), CON UN ALDEHIDO DE FORMULA (III), EN PRESENCIA DE SALES DE ACETATO DE AMINAS COMO CATALIZADOR, FORMULAS EN LAS QUE R1-R5 PUEDEN SER VARIOS TIPOS DE RADICALES; TRATAMIENTO DEL ILIDEN-COMPUESTO FORMADO CON UNA ENAMINA ADECUADA PARA FORMAR UNA DIHIDROPIRIDINA; COMBINACION DE ESTA CON UN BLOQUEADOR BETA SIN EFECTO ANESTESICO LOCAL, Y TRANSFORMACION DE AMBOS COMPONENTES EN UNA FORMA DE APLICACION ADECUADA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843427402 DE3427402A1 (de) | 1984-07-25 | 1984-07-25 | Neues kombinationspraeparat, verfahren zu seiner herstellung und seine verwendung als arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
ES545522A0 ES545522A0 (es) | 1986-07-16 |
ES8608887A1 true ES8608887A1 (es) | 1986-07-16 |
Family
ID=6241524
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES545522A Expired ES8608887A1 (es) | 1984-07-25 | 1985-07-24 | Procedimiento para la obtencion de preparados combinados antihipertensores y antianginicos a base de dihidropiridina y bloquear beta. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0169470A3 (es) |
JP (1) | JPS6144816A (es) |
KR (1) | KR860000870A (es) |
AU (1) | AU576608B2 (es) |
CA (1) | CA1255596A (es) |
DE (1) | DE3427402A1 (es) |
DK (1) | DK338185A (es) |
ES (1) | ES8608887A1 (es) |
GR (1) | GR851823B (es) |
IL (1) | IL75873A (es) |
PT (1) | PT80852B (es) |
ZA (1) | ZA855584B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3424553A1 (de) * | 1984-07-04 | 1986-01-09 | Bayer Ag, 5090 Leverkusen | Feste arzneizubereitungen mit dihydropyridinen und verfahren zu ihrer herstellung |
DE3447170A1 (de) * | 1984-12-22 | 1986-07-03 | Bayer Ag, 5090 Leverkusen | Mischung unterschiedlicher dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
DE3610037A1 (de) * | 1986-03-21 | 1987-09-24 | Schering Ag | Nifedipinkombinationspraeparat |
IE59540B1 (en) * | 1987-01-09 | 1994-03-09 | Elan Corp | Sustained release capsule or tablet formulation |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2084017B (en) * | 1980-09-18 | 1984-08-22 | Sandoz Ltd | Pharmaceutical compositions effective against coronary heat disease and hypertension |
DE3419130A1 (de) * | 1984-05-23 | 1985-11-28 | Bayer Ag, 5090 Leverkusen | Nifedipinkombinationspraeparate und verfahren zu ihrer herstellung |
DE3419131A1 (de) * | 1984-05-23 | 1985-11-28 | Bayer Ag, 5090 Leverkusen | Dihydropyridinkombinationspraeparate und verfahren zu ihrer herstellung |
-
1984
- 1984-07-25 DE DE19843427402 patent/DE3427402A1/de not_active Withdrawn
-
1985
- 1985-06-26 CA CA000485285A patent/CA1255596A/en not_active Expired
- 1985-07-15 EP EP85108806A patent/EP0169470A3/de not_active Withdrawn
- 1985-07-22 IL IL75873A patent/IL75873A/xx unknown
- 1985-07-23 AU AU45285/85A patent/AU576608B2/en not_active Ceased
- 1985-07-23 KR KR1019850005239A patent/KR860000870A/ko not_active Application Discontinuation
- 1985-07-23 GR GR851823A patent/GR851823B/el unknown
- 1985-07-23 PT PT80852A patent/PT80852B/pt not_active IP Right Cessation
- 1985-07-24 ZA ZA855584A patent/ZA855584B/xx unknown
- 1985-07-24 JP JP60162170A patent/JPS6144816A/ja active Pending
- 1985-07-24 ES ES545522A patent/ES8608887A1/es not_active Expired
- 1985-07-24 DK DK338185A patent/DK338185A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DK338185D0 (da) | 1985-07-24 |
CA1255596A (en) | 1989-06-13 |
IL75873A0 (en) | 1985-11-29 |
JPS6144816A (ja) | 1986-03-04 |
ES545522A0 (es) | 1986-07-16 |
DK338185A (da) | 1986-01-26 |
ZA855584B (en) | 1986-03-26 |
DE3427402A1 (de) | 1986-01-30 |
EP0169470A3 (de) | 1988-11-02 |
EP0169470A2 (de) | 1986-01-29 |
AU4528585A (en) | 1986-01-30 |
IL75873A (en) | 1988-11-30 |
PT80852A (en) | 1985-08-01 |
KR860000870A (ko) | 1986-02-20 |
GR851823B (es) | 1985-11-26 |
PT80852B (pt) | 1987-11-30 |
AU576608B2 (en) | 1988-09-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK130293A (en) | Phenyl carbamates | |
MX9700273A (es) | Benzamidinas sustituidas, su preparacion y empleo como sustancias medicamentosas. | |
PL289487A1 (en) | Method of producing new aminophenol derivatives | |
UA39101C2 (uk) | ПОХІДНІ 11<font face="Symbol">b</font>-БЕНЗАЛЬДОКСИМ-ЕСТРА-4,9-ДІЄНУ, СПОСІБ ЇХ ОДЕРЖАННЯ І ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ З АНТИПРОГЕСТИНОВОЮ АКТИВНІСТЮ | |
EP0165458A3 (en) | (+)-ambrox, process for production thereof and use thereof | |
JPS6413070A (en) | Novel compound, manufacture and medicinal composition | |
PT80191A (en) | Process for preparing substituted benzopyrans useful as medicaments | |
ES8607271A1 (es) | Amidinohidrazonas | |
UA26403A (uk) | Похідhі n-заміщеhого 4-феhіл-4-піперидиhкарбоксаміду та їх фармацевтичhо прийhятhі солі, що проявляють аhестезувальhу та аhальгезувальhу дію, спосіб їх одержаhhя та фармацевтичhа композиція | |
HUT41784A (en) | Process for producing 1,8-naphtiridine derivatives and pharmaceutical compositions containing them as active agents | |
AU1413788A (en) | Dihydropyridinamides process for their preparation, and their use in medicaments | |
ES8608887A1 (es) | Procedimiento para la obtencion de preparados combinados antihipertensores y antianginicos a base de dihidropiridina y bloquear beta. | |
PT83472B (pt) | Processo para a preparacao de composicoes anti-inflamatorias aperfeicoadas contendo piroxicamo | |
IL75814A0 (en) | Dihydropyridines,their production and pharmaceutical compositions containing them | |
ES8305717A1 (es) | Procedimiento para la obtencion de derivados de 2-amino-3,4-dihidropiridina sustituidos. | |
HUT40648A (en) | Process for producing optically active substituted 1,4-dihydro-pyridines and pharmaceutical compositions containing them as active agents | |
MY100083A (en) | Diazepinoindoles, their production and pharmaceutical compositions containing them. | |
ZA852554B (en) | Novel substituted benzodioxole derivatives,processes for their manufacture and corresponding pharmaceutical compositions | |
ES8708226A1 (es) | Procedimiento para la produccion de derivados de 1,4-dihi- dropiridina | |
HUT37764A (en) | Process for producing 1,4-dihydro-pyrazines and pharmaceutical compositions containing them as active agents | |
ES8706660A1 (es) | Un procedimiento para preparar (aminoalquiltio)hidroxidibenzoxepinas | |
EG17329A (en) | Process for preparing of 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents | |
ES8606375A1 (es) | Un procedimiento para preparar un derivado de aminoprpilaminobleomicina | |
ES8606868A1 (es) | Procedimiento para la obtencion de derivados de la 1,4-dihi-dro-piridina | |
IT8448711A1 (it) | Composti 1,2,4 - triazolici procedimento per produrli e composizioni farmaceutiche che li contengono. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed |
Effective date: 19960506 |