ES8608887A1 - Procedimiento para la obtencion de preparados combinados antihipertensores y antianginicos a base de dihidropiridina y bloquear beta. - Google Patents

Procedimiento para la obtencion de preparados combinados antihipertensores y antianginicos a base de dihidropiridina y bloquear beta.

Info

Publication number
ES8608887A1
ES8608887A1 ES545522A ES545522A ES8608887A1 ES 8608887 A1 ES8608887 A1 ES 8608887A1 ES 545522 A ES545522 A ES 545522A ES 545522 A ES545522 A ES 545522A ES 8608887 A1 ES8608887 A1 ES 8608887A1
Authority
ES
Spain
Prior art keywords
mixture
drug
application
manufacturing process
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES545522A
Other languages
English (en)
Other versions
ES545522A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6241524&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8608887(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES545522A0 publication Critical patent/ES545522A0/es
Publication of ES8608887A1 publication Critical patent/ES8608887A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

METODO DE PREPARACION DE COMPOSICIONES A BASE DE DIHIDROPIRIDINA Y BLOQUEADOR BETA, QUE TIENEN APLICACIONES FARMACOLOGICAS POR SU EFECTO ANTIHIPERTENSOR Y ANTIANGINICO. COMPRENDE LA REACCION DE UN ACIDO CETOCARBOXILICO DE FORMULA (I) O (II), CON UN ALDEHIDO DE FORMULA (III), EN PRESENCIA DE SALES DE ACETATO DE AMINAS COMO CATALIZADOR, FORMULAS EN LAS QUE R1-R5 PUEDEN SER VARIOS TIPOS DE RADICALES; TRATAMIENTO DEL ILIDEN-COMPUESTO FORMADO CON UNA ENAMINA ADECUADA PARA FORMAR UNA DIHIDROPIRIDINA; COMBINACION DE ESTA CON UN BLOQUEADOR BETA SIN EFECTO ANESTESICO LOCAL, Y TRANSFORMACION DE AMBOS COMPONENTES EN UNA FORMA DE APLICACION ADECUADA.
ES545522A 1984-07-25 1985-07-24 Procedimiento para la obtencion de preparados combinados antihipertensores y antianginicos a base de dihidropiridina y bloquear beta. Expired ES8608887A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843427402 DE3427402A1 (de) 1984-07-25 1984-07-25 Neues kombinationspraeparat, verfahren zu seiner herstellung und seine verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
ES545522A0 ES545522A0 (es) 1986-07-16
ES8608887A1 true ES8608887A1 (es) 1986-07-16

Family

ID=6241524

Family Applications (1)

Application Number Title Priority Date Filing Date
ES545522A Expired ES8608887A1 (es) 1984-07-25 1985-07-24 Procedimiento para la obtencion de preparados combinados antihipertensores y antianginicos a base de dihidropiridina y bloquear beta.

Country Status (12)

Country Link
EP (1) EP0169470A3 (es)
JP (1) JPS6144816A (es)
KR (1) KR860000870A (es)
AU (1) AU576608B2 (es)
CA (1) CA1255596A (es)
DE (1) DE3427402A1 (es)
DK (1) DK338185A (es)
ES (1) ES8608887A1 (es)
GR (1) GR851823B (es)
IL (1) IL75873A (es)
PT (1) PT80852B (es)
ZA (1) ZA855584B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3424553A1 (de) * 1984-07-04 1986-01-09 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen mit dihydropyridinen und verfahren zu ihrer herstellung
DE3447170A1 (de) * 1984-12-22 1986-07-03 Bayer Ag, 5090 Leverkusen Mischung unterschiedlicher dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
DE3610037A1 (de) * 1986-03-21 1987-09-24 Schering Ag Nifedipinkombinationspraeparat
IE59540B1 (en) * 1987-01-09 1994-03-09 Elan Corp Sustained release capsule or tablet formulation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2084017B (en) * 1980-09-18 1984-08-22 Sandoz Ltd Pharmaceutical compositions effective against coronary heat disease and hypertension
DE3419130A1 (de) * 1984-05-23 1985-11-28 Bayer Ag, 5090 Leverkusen Nifedipinkombinationspraeparate und verfahren zu ihrer herstellung
DE3419131A1 (de) * 1984-05-23 1985-11-28 Bayer Ag, 5090 Leverkusen Dihydropyridinkombinationspraeparate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
AU4528585A (en) 1986-01-30
GR851823B (es) 1985-11-26
ES545522A0 (es) 1986-07-16
EP0169470A2 (de) 1986-01-29
JPS6144816A (ja) 1986-03-04
DK338185A (da) 1986-01-26
EP0169470A3 (de) 1988-11-02
CA1255596A (en) 1989-06-13
ZA855584B (en) 1986-03-26
PT80852B (pt) 1987-11-30
AU576608B2 (en) 1988-09-01
KR860000870A (ko) 1986-02-20
DE3427402A1 (de) 1986-01-30
PT80852A (en) 1985-08-01
IL75873A0 (en) 1985-11-29
DK338185D0 (da) 1985-07-24
IL75873A (en) 1988-11-30

Similar Documents

Publication Publication Date Title
PT82127A (en) Process for the preparation of phenyl carbamates
MX9700273A (es) Benzamidinas sustituidas, su preparacion y empleo como sustancias medicamentosas.
PL289487A1 (en) Method of producing new aminophenol derivatives
UA39101C2 (uk) ПОХІДНІ 11<font face="Symbol">b</font>-БЕНЗАЛЬДОКСИМ-ЕСТРА-4,9-ДІЄНУ, СПОСІБ ЇХ ОДЕРЖАННЯ І ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ З АНТИПРОГЕСТИНОВОЮ АКТИВНІСТЮ
EP0165458A3 (en) (+)-ambrox, process for production thereof and use thereof
JPS6413070A (en) Novel compound, manufacture and medicinal composition
EP0411733A3 (en) 11-beta-aryle-gona-4,9-dien-3-ones
PT80191A (en) Process for preparing substituted benzopyrans useful as medicaments
ES8607271A1 (es) Amidinohidrazonas
YU12000A (sh) Supstituisani 1,2,3,4,5,6-heksahidro-2,6-metano-3-benzazocin -10-oli, postupak za njihovo pripremanje i njihova primena kao lekova
HUT41784A (en) Process for producing 1,8-naphtiridine derivatives and pharmaceutical compositions containing them as active agents
AU1413788A (en) Dihydropyridinamides process for their preparation, and their use in medicaments
ES8608887A1 (es) Procedimiento para la obtencion de preparados combinados antihipertensores y antianginicos a base de dihidropiridina y bloquear beta.
PT83472B (pt) Processo para a preparacao de composicoes anti-inflamatorias aperfeicoadas contendo piroxicamo
EP0183538A3 (en) 2,2' -isopropylidine bis (tetrahydrofuran) and method of preparation
IL75814A0 (en) Dihydropyridines,their production and pharmaceutical compositions containing them
ES8305717A1 (es) Procedimiento para la obtencion de derivados de 2-amino-3,4-dihidropiridina sustituidos.
HUT40648A (en) Process for producing optically active substituted 1,4-dihydro-pyridines and pharmaceutical compositions containing them as active agents
MY100083A (en) Diazepinoindoles, their production and pharmaceutical compositions containing them.
JPS6470470A (en) Novel 1,2-diamino compound, manufacture and drug
ZA852554B (en) Novel substituted benzodioxole derivatives,processes for their manufacture and corresponding pharmaceutical compositions
ES8708226A1 (es) Procedimiento para la produccion de derivados de 1,4-dihi- dropiridina
HUT37764A (en) Process for producing 1,4-dihydro-pyrazines and pharmaceutical compositions containing them as active agents
EG17329A (en) Process for preparing of 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents
ES8606375A1 (es) Un procedimiento para preparar un derivado de aminoprpilaminobleomicina

Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506