ES8703448A1 - Procedimiento para la obtencion de neuropiranos sustituibles. - Google Patents

Procedimiento para la obtencion de neuropiranos sustituibles.

Info

Publication number
ES8703448A1
ES8703448A1 ES541583A ES541583A ES8703448A1 ES 8703448 A1 ES8703448 A1 ES 8703448A1 ES 541583 A ES541583 A ES 541583A ES 541583 A ES541583 A ES 541583A ES 8703448 A1 ES8703448 A1 ES 8703448A1
Authority
ES
Spain
Prior art keywords
medicines
preparation
benzopyrans
substituted
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES541583A
Other languages
English (en)
Other versions
ES541583A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES8703448A1 publication Critical patent/ES8703448A1/es
Publication of ES541583A0 publication Critical patent/ES541583A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Glass Compositions (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
  • Dental Preparations (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE BENZOPIRANOS SUSTITUIDOS. CONSISTE EN HACER REACCIONAR, A UNA TEMPERATURA ENTRE C50 Y 50JC, UNA AMINA DE FORMULA (II) CON CARBONIL COMPUESTO DE FORMULA (III), PARA OBTENER BENZOPIRANOS SUSTITUIDOS DE FORMULA (I) EN DONDE A ES UN ENLACE SENCILLO O DOBLE; R1 Y R2 SON ALQUILO, CICLOALQUILO, ARILO Y OTROS; R3, R4, R5 Y R6 SON H, HIDROXI, HALOGENO, ALQUILO, CICLOALQUILO, ARILO Y OTROS; R7, R8, R9, R10 Y R11 SON H O ALQUILO; X ES METILO SUSTITUIDO; R17 ES H, ALQUILO CON HASTA 6 ATOMOS DE CARBONO Y OTROS; Y R12, R13, R14, R15 Y R16 SON H, HIDROXI, HALOGENO, ALQUILO Y OTROS. TIENEN APLICACIONES FARMACOLOGICAS COMO INFLUENCIADORES DEL SISTEMA NERVIOSO.
ES541583A 1984-03-31 1985-03-26 Procedimiento para la obtencion de neuropiranos sustituibles. Expired ES8703448A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843411993 DE3411993A1 (de) 1984-03-31 1984-03-31 Substituierte benzopyrane, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimittel

Publications (2)

Publication Number Publication Date
ES8703448A1 true ES8703448A1 (es) 1987-02-16
ES541583A0 ES541583A0 (es) 1987-02-16

Family

ID=6232185

Family Applications (2)

Application Number Title Priority Date Filing Date
ES541583A Expired ES8703448A1 (es) 1984-03-31 1985-03-26 Procedimiento para la obtencion de neuropiranos sustituibles.
ES556864A Expired ES8801912A1 (es) 1984-03-31 1986-07-01 Procedimiento para la obtencion de benzopiranos sustituidos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES556864A Expired ES8801912A1 (es) 1984-03-31 1986-07-01 Procedimiento para la obtencion de benzopiranos sustituidos.

Country Status (17)

Country Link
US (1) US4659737A (es)
EP (1) EP0157267B1 (es)
JP (1) JPS60224685A (es)
KR (1) KR850006194A (es)
AT (1) ATE38836T1 (es)
AU (1) AU4059485A (es)
DE (2) DE3411993A1 (es)
DK (1) DK144685A (es)
ES (2) ES8703448A1 (es)
FI (1) FI851261L (es)
GR (1) GR850799B (es)
HU (1) HUT38097A (es)
IL (1) IL74745A0 (es)
NO (1) NO851010L (es)
NZ (1) NZ211617A (es)
PT (1) PT80191B (es)
ZA (1) ZA852391B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4918092A (en) * 1983-12-21 1990-04-17 Merck Frosst Canada, Inc. Leukotriene antagonists
ATE65084T1 (de) * 1986-06-26 1991-07-15 Ciba Geigy Ag Hydrierte 1-benzooxacycloalkylpyridincarbons|ureverbindungen.
FR2618437B1 (fr) * 1987-07-23 1989-11-17 Rhone Poulenc Sante Nouveaux derives du benzopyranne, leur preparation et les medicaments qui les contiennent
DE3737195A1 (de) * 1987-11-03 1989-05-18 Bayer Ag Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
ES2059828T3 (es) * 1988-01-15 1994-11-16 Abbott Lab Un procedimiento para la preparacion de un compuesto.
US5185364A (en) * 1988-01-15 1993-02-09 Abbott Laboratories Aminomethyl-chroman and -thiochroman compounds
US5140039A (en) * 1988-01-15 1992-08-18 Abbott Laboratories Aminomethyl-thiochroman compounds
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
US5264458A (en) * 1989-11-02 1993-11-23 Bayer Aktiengesellschaft Antithrombotic iso- and heterocyclic phenylsulphonamides
WO1992008712A1 (en) * 1990-11-08 1992-05-29 Yamanouchi Pharmaceutical Co., Ltd. Flavane derivative or salt thereof and novel production process
US5837702A (en) * 1993-10-07 1998-11-17 Bristol-Myers Squibb Co. 4-arylamino-benzopyran and related compounds
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
GB9801392D0 (en) * 1998-01-22 1998-03-18 Smithkline Beecham Plc Novel compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH648030A5 (de) * 1980-12-15 1985-02-28 Sandoz Ag Benzopyran-allylaminderivate, verfahren zu ihrer herstellung und ihre verwendung.
DE3300004A1 (de) * 1983-01-03 1984-07-12 Bayer Ag, 5090 Leverkusen Substituierte 4-aminomethylenchromane bzw. -chromene, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
NO851010L (no) 1985-10-01
ES8801912A1 (es) 1987-08-01
DE3411993A1 (de) 1985-10-10
NZ211617A (en) 1987-10-30
EP0157267A2 (de) 1985-10-09
FI851261L (fi) 1985-10-01
IL74745A0 (en) 1985-06-30
FI851261A0 (fi) 1985-03-28
EP0157267B1 (de) 1988-11-23
AU4059485A (en) 1985-10-03
ES541583A0 (es) 1987-02-16
KR850006194A (ko) 1985-10-02
ES556864A0 (es) 1987-08-01
PT80191B (en) 1987-03-18
PT80191A (en) 1985-04-01
US4659737A (en) 1987-04-21
DK144685D0 (da) 1985-03-29
DE3566404D1 (en) 1988-12-29
EP0157267A3 (en) 1986-09-03
GR850799B (es) 1985-11-25
HUT38097A (en) 1986-04-28
JPS60224685A (ja) 1985-11-09
ZA852391B (en) 1985-11-27
ATE38836T1 (de) 1988-12-15
DK144685A (da) 1985-10-01

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